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Aggregate Level (aggregate + level)
Selected AbstractsGerman Exchange Rate Exposure at DAX and Aggregate Levels, International Trade and the Role of Exchange Rate Adjustment CostsGERMAN ECONOMIC REVIEW, Issue 3 2007Horst Entorf Exchange rate exposure; macroeconomic risks; financial panel econometrics Abstract. This article analyses value changes of German stock market companies in response to movements of the US dollar. The approach followed in this work extends the standard means of measuring exchange rate exposure in several ways, e.g. by using multifactor modelling instead of augmented Capital Asset Pricing Model, application of moving window panel regressions and orthogonalization of overall market risk vis-à-vis currency risk. A further innovation lies in testing the theoretical implications of exchange rate adjustment costs (hedging costs) for firm values and economic exposure. Based on time series and panel data of German Deutsche Aktien Xchange companies, Deutsche Mark/dollar rates and macroeconomic factors, we find a rather unstable, time-variant exposure of German stock market companies. Dollar sensitivity is positively affected by the ratio of exports/gross domestic product (GDP) and negatively affected by imports/GDP. Moreover, as expected from theoretical findings, firm values and exchange rate exposure are significantly reduced by adjustment costs depending on the distance of the exchange rate from the expected long-run mean. [source] A Multilevel Analysis of Gender Differences in Psychological Distress Over TimeJOURNAL OF RESEARCH ON ADOLESCENCE, Issue 2 2009Amanda L. Botticello Females have higher rates of depression than males, a disparity that emerges in adolescence and persists into adulthood. This study uses hierarchical linear modeling to assess the effects of school context on gender differences in depressive symptoms among adolescents based on two waves of data from the National Longitudinal Study of Adolescent Health (N=9,709 teens, 127 schools). Analysis indicates significant school-level variation in both overall symptom levels and the average gender gap in depression net of prior symptoms and individual-level covariates. Aggregate levels of depressive symptomatology were positively associated with contextual-level socioeconomic status (SES) disadvantage. A cross-level contingency emerged for the relationship between gender and depressive symptoms with school SES and aggregate perceived community safety such that the gender "gap" was most apparent in contexts characterized by low SES disadvantage and high levels of perceived safety. These results highlight the importance of context to understanding the development of mental health disparities. [source] Lessons learned from the clinical reappraisal study of the Composite International Diagnostic Interview with LatinosINTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue 2 2009Margarita Alegria Abstract Given recent adaptations of the World Health Organization's World Mental Health Composite International Diagnostic Interview (WMH-CIDI), new methodological studies are needed to evaluate the concordance of CIDI diagnoses with clinical diagnostic interviews. This paper summarizes lessons learned from a clinical reappraisal study done with US Latinos. We compare CIDI diagnoses with independent clinical diagnosis using the World Mental Health Structured Clinical Interview for DSM-IV (WMH-SCID 2000). Three sub-samples stratified by diagnostic status (CIDI positive, CIDI negative, or CIDI sub-threshold for a disorder) based on nine disorders were randomly selected for a telephone re-interview using the SCID. We calculated sensitivity, specificity, and weight-adjusted Cohen's kappa. Weighted 12 month prevalence estimates of the SCID are slightly higher than those of the CIDI for generalized anxiety disorder, alcohol abuse/dependence, and drug abuse/dependence. For Latinos, CIDI-SCID concordance at the aggregate disorder level is comparable, albeit lower, to other published reports. The CIDI does very well identifying negative cases and classifying disorders at the aggregate level. Good concordance was also found for major depressive episode and panic disorder. Yet, our data suggests that the CIDI presents problems for assessing post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD). Recommendations on how to improve future versions of the CIDI for Latinos are offered. Copyright © 2009 John Wiley & Sons, Ltd. [source] The potential power of social policy programmes: income redistribution, economic resources and healthINTERNATIONAL JOURNAL OF SOCIAL WELFARE, Issue 2010Olle Lundberg Lundberg O, Fritzell J, Åberg Yngwe M, Kölegård ML. The potential power of social policy programmes: income redistribution, economic resources and health Int J Soc Welfare 2010: ,,: ,,,,,© 2010 The Author(s), Journal compilation © 2010 Blackwell Publishing Ltd and International Journal of Social Welfare. This Supplement includes a number of articles dealing with the role of social policy schemes for public health across the life course. As a key social determinant of health, poverty and its consequences have historically been at the forefront of the public health discussion. But also in rich countries today, economic resources are likely to be important for health and survival, both on an individual and an aggregate level. This introductory article serves as a background for the more specific analyses that follow. The focus is on why income and income inequality could have an effect on individual and population health. We discuss relationships between the individual and population levels and between income and health, and some of the possible mechanisms involved. We also present arguments for why welfare state institutions may matter. [source] Urban ecological footprints in AfricaAFRICAN JOURNAL OF ECOLOGY, Issue 4 2008Joy S. Clancy Abstract Africa's rate of urbanization is the highest in the world. This is relevant to ecologists working in Africa because urban growth is strongly associated with habitat destruction, and also creates new fields of study. The ecological footprint concept is used to illustrate how urban settlements in Africa impact on rural ecosystems. At an aggregate level, African countries have the lowest ecological footprints in the world. However, there is little available data for individual cities, so evidence is fragmented making concerted policy initiatives difficult. Wood fuel continues to be a major source of energy for urban households and there is a long running debate as to what extent providing wood fuel for urban use damages forest ecosystems. Growing evidence contests the assertion that urban wood fuel markets are responsible for forest degradation. Although there are other options available, the social consequences of switching energy sources need to be taken into account. Outright bans, for example on charcoal, would lead to a loss of livelihoods in rural and urban households, and may not solve deforestation as well as increasing fossil fuel use would increase the ecological footprint. Résumé Le taux d'urbanisation de l'Afrique est le plus élevé du monde. Cela concerne les écologistes qui travaillent sur ce continent parce que la croissance urbaine est étroitement liée à la destruction des habitats, et cela ouvre aussi de nouveaux champs d'étude. Le concept d'empreinte écologique est utilisé pour illustrer comment les installations urbaines en Afrique ont un impact sur les écosystèmes ruraux. Pris tous ensemble, ce sont les pays africains qui ont la plus légère empreinte écologique du monde. Cependant, nous disposons de peu de données pour des villes individuelles, de sorte que les renseignements sont fragmentés et qu'il est difficile de prendre des initiatives politiques concertées. Le bois de feu continue àêtre une des principales sources d'énergie pour les ménages urbains, et il existe un débat de longue haleine quant à savoir dans quelle mesure l'approvisionnement en bois pour la consommation urbaine endommage les écosystèmes forestiers. Des preuves de plus en plus évidentes remettent en question l'assertion selon laquelle les marchés urbains de bois de feu seraient responsables de la dégradation des forêts. Bien qu'il y ait d'autres options possibles, il faut prendre en compte les conséquences sociales du passage à d'autres sources d'énergie. Les interdictions totales, par exemple du charbon de bois, entraîneraient la perte des moyens de subsistance de ménages ruraux et urbains, et pourraient ne pas résoudre le problème de déforestation, tout comme l'utilisation accrue des combustibles fossiles augmenterait l'empreinte écologique. [source] Determining if disease management saves money: an introduction to meta-analysisJOURNAL OF EVALUATION IN CLINICAL PRACTICE, Issue 3 2007Ariel Linden DrPH MS Abstract Disease management (DM) programmes have long been promoted as a major medical cost-saving mechanism, even though the scant research that exists on the topic has provided conflicting results. In a 2004 literature review, the Congressional Budget Office stated that ,there is insufficient evidence to conclude that disease management programs can generally reduce the overall cost of health care services'. To address this question more accurately, a meta-analysis was warranted. Meta-analysis is the quantitative technique used to pool the results of many studies on the same topic and summarize them statistically. This method is also quite suitable for individual DM firms to assess whether their programmes are effective at the aggregate level. This paper describes the elements of a rigorous meta-analytic process and discusses potential biases. A hypothetical DM organization is then evaluated with a specific emphasis on medical cost-savings, simulating a case in which different populations are served, evaluation methodologies are employed, and diseases are managed. [source] Is Neoclassical Economics still Entrepreneurless?KYKLOS INTERNATIONAL REVIEW OF SOCIAL SCIENCES, Issue 3 2005Milo Bianchi Summary The paper reviews and evaluates some recent contributions on modeling entrepreneurship within a neoclassical framework, analyzing how, and to what extent, the fundamental ingredients suggested in the social science literature were captured. It is shown how these approaches are important in stressing the main elements of a complex picture, without being able to fully describe it. Each modeling attempt focuses only on one specific feature of entrepreneurship, and the entrepreneurial function, broadly perceived, eludes analytical tractability. As a consequence, the models can be useful in analyzing the effect of entrepreneurial behavior at an aggregate level, but not at explaining individual choices. From these observations, it is highlighted how a simplistic interpretation of the existing mainstream approaches incorporating entrepreneurship runs the risk of leading to distortionary policy interventions. [source] Sources of Mass Partisanship in BrazilLATIN AMERICAN POLITICS AND SOCIETY, Issue 2 2006David Samuels ABSTRACT Scholars believe that mass partisanship in Brazil is comparatively weak. Using evidence from a 2002 national survey, however, this study finds that the aggregate level of party identification actually falls only slightly below the world average and exceeds levels found in many newer democracies. Yet this finding is misleading, because the distribution of partisanship is skewed toward only one party, the PT. This trend results from a combination of party organization and recruitment efforts and individual motivation to acquire knowledge and become involved in politicized social networks. Partisanship for other parties, however, derives substantially from personalistic attachments to party leaders. This finding has implications for current debates about the status of parties in Brazil. Also important is the impact of the 2005 corruption scandal implicating the PT and President Lula da Silva's administration. [source] Modeling Socioeconomic Class in Variationist SociolinguisticsLINGUISTICS & LANGUAGE COMPASS (ELECTRONIC), Issue 5 2009Robin Dodsworth Modeling socioeconomic class has been a persistent challenge in the analysis of sociolinguistic variation. While early stratificational models formulated on the basis of socioeconomic indicators such as income, occupation, and area of residence revealed compelling patterns of linguistic variation, they were critiqued for their lack of explanatory power at the interactional level and for their marginalization of those without paid employment. Subsequent models have employed cross-disciplinary concepts such as the linguistic market, social networks, and communities of practice, prioritizing local social distinctions that are understood to reflect or even constitute abstract structural categories such as ,working class' or ,middle class'. It is argued that a full socioeconomic class paradigm for sociolinguistics would also theorize class at the aggregate level, and to this end, sociological class models may prove useful. Contemporary sociological class analysis at the level of social practice offers additional avenues for interfacing with sociology. [source] Does the Colour of the Cat Matter?MANAGEMENT AND ORGANIZATION REVIEW, Issue 1 2007The Red Hat Strategy in China's Private Enterprises abstract The proliferation of new property rights regimes in transitional economies provided an opportunity to examine the interaction between institutions and organizations. Some private enterprises in China developed the Red Hat strategy whereby they disguised their private ownership by registering as a public-owned organization. Drawing on a national survey, this study investigated how institutional variations, transaction costs and social embeddedness affected the firms' Red Hat strategy. The findings suggest that private firms preferred a fuzzy property rights arrangement in the early years of market transition. The temporal and regional variation of the institutional environment contributed to the adoption of the Red Hat strategy. High transaction costs , networking cost and resource constraints , were positively related to the adoption of the Red Hat strategy. Social embeddedness also played an important role. The reliance on transaction partners in the public sector increased the pressure to adopt the Red Hat, while connections with high-ranking cadres facilitated the process. However, private firms opted for clearly delineated property rights as the institutional environment improved. In turn, the decisions of individual firms affected the institutional environment at the aggregate level. The Red Hat strategy exemplifies the co-evolution of institutional change and organizational dynamics. [source] The Effects of the George W. Bush Presidency on Partisan AttitudesPRESIDENTIAL STUDIES QUARTERLY, Issue 2 2009GARY C. JACOBSON Evidence from the eight years of the George W. Bush administration confirms that the public standing of the president's party rises and falls in concert with popular evaluations of his job performance. Reactions to the president affect the favorability ratings of his party, party identification measured individually and at the aggregate level,particularly among younger voters,as well as the party's electoral performance. Bush's second term, which provoked the longest period of low and downward-trending approval ratings on record, thus inflicted considerable damage on the Republican Party's image, popular support, and electoral fortunes. [source] The Elasticity of Demand for Labour in AustraliaTHE ECONOMIC RECORD, Issue 240 2002Philip E. T. Lewis The elasticity of demand for labour at the aggregate level is an important parameter for macroeconomic analysis. In particular, policy issues concerning the impact of wage falls on employment and unemployment hinge on the size of this parameter. It is argued in the present paper that previous work on the elasticity of demand for labour in Australia has been unsatisfactory in a number of ways. A new set of estimates is provided that are derived using a better methodology than before. [source] Who Gambles in the Stock Market?THE JOURNAL OF FINANCE, Issue 4 2009ALOK KUMAR ABSTRACT This study shows that the propensity to gamble and investment decisions are correlated. At the aggregate level, individual investors prefer stocks with lottery features, and like lottery demand, the demand for lottery-type stocks increases during economic downturns. In the cross-section, socioeconomic factors that induce greater expenditure in lotteries are associated with greater investment in lottery-type stocks. Further, lottery investment levels are higher in regions with favorable lottery environments. Because lottery-type stocks underperform, gambling-related underperformance is greater among low-income investors who excessively overweight lottery-type stocks. These results indicate that state lotteries and lottery-type stocks attract very similar socioeconomic clienteles. [source] One little Lebanese cucumber is not going to break the bank: Price in the choice of fresh fruits and vegetablesAUSTRALIAN JOURNAL OF AGRICULTURAL & RESOURCE ECONOMICS, Issue 2 2002Kate M. Owen This paper reports on empirical research into individual consumer behaviour in the context of fresh fruit and vegetable purchases. The discussion draws on research results from two studies conducted around the actual shopping process. The findings suggest that consumers' price response behaviour may not be consistent with that predicted by economic theory and that this could be significant at the aggregate level. The existence of ,acceptable price ranges' points to the presence of price thresholds within which consumers are relatively insensitive to price movements. Also of relevance is that the primary influence of the budget constraint may be at a broader level rather than at the level of choosing particular products. [source] Effect of antibody solution conditions on filter performance for virus removal filter PlanovaÔ 20NBIOTECHNOLOGY PROGRESS, Issue 4 2010Tomoko Hongo-Hirasaki Abstract We investigated the effect of antibody solution conditions (ionic strength, pH, IgG concentration, buffer composition, and aggregate level (dimer content)) on filter performance for a virus removal filtration process using the PlanovaÔ 20N, a virus removal filter. Ionic strength and pH affected the filter flux. A consistent high flux was maintained at an ionic strength greater than 10 mM and at pH 4,8 under a typical buffer composition (sodium chloride, citrate, acetate, and phosphate). Optimum IgG concentration was 10,20 mg/mL allowing for high throughput (kg/m2 of IgG). Dimer content negligibly affected the flux level. Under high throughput conditions, virus spiking did not affect flux whereas a parvovirus logarithmic reduction value greater than 5 was maintained. From the results of zeta potential analyses for IgG and the membrane, we considered that electrostatic interactions between antibodies and the membrane affect filter performance (flux level and throughput). These results indicate that the PlanovaÔ 20N filter is applicable for a wide range of solution conditions typically used in antibody processing. © 2010 American Institute of Chemical Engineers Biotechnol. Prog., 2010 [source] SOCIAL SUPPORT, INEQUALITY, AND HOMICIDE: A CROSS-NATIONAL TEST OF AN INTEGRATED THEORETICAL MODEL,CRIMINOLOGY, Issue 3 2003TRAVIS C. PRATT Social support, institutional anomie, and macrolevel general strain perspectives have emerged as potentially important explanations of aggregate levels of crime. Drawing on insights from each of these perspectives in a cross-national context, the analyses show that 1) our measure of social support is inversely related to homicide rates, 2) economic inequality also maintains a direct relationship with homicide rates, and 3) social support significantly interacts with economic inequality to influence homicide rates. The implications of the analysis for ongoing discourse concerning the integration of these criminological theories and the implications for the development of effective crime control policies are discussed. [source] Estimating arable output using Durham Priory tithe receipts, 1341,1450ECONOMIC HISTORY REVIEW, Issue 2 2004BEN DODDS Research on English late medieval economic history has neglected the evidence of tithes as indicators of agrarian output. In this article, methods used by historians of continental Europe have been developed and applied to the Durham Priory accounting material in order to create the first series of tithe-based production indicators for medieval England. The data are manipulated, and presented, to provide insight into long- and short-term trends in aggregate levels of arable production. The series of indicators are then used to examine the evidence for falling output in the late middle ages in the light of our understanding of demographic, economic, and climatic factors. [source] Self-buffering antibody formulationsJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 8 2008Yatin R. Gokarn Abstract Monoclonal antibodies (mAbs) often require the development of high-concentration formulations. In such cases, and when it is desirable to formulate a mAb around pH 5.0, we explored a novel approach of controlling the formulation pH by harnessing the ability of mAbs to "self-buffer." Buffer capacities of four representative IgG2 molecules (designated mAb1 through mAb4) were measured in the pH 4,6 range. The buffer capacity results indicated that the mAbs possessed a significant amount of buffer capacity, which increased linearly with concentration. By 60,80 mg/mL, the mAb buffer capacities surpassed that of 10 mM acetate, which is commonly employed in formulations for buffering in the pH 4,6 range. Accelerated high temperature stability studies (50°C over 3 weeks) conducted with a representative antibody in a self-buffered formulation (50 mg/mL mAb1 in 5.25% sorbitol, pH 5.0) and with solutions formulated using conventional buffers (50 mg/mL mAb1 in 5.25% sorbitol, 25 or 50 mM acetate, glutamate or succinate, also at pH 5.0) indicated that mAb1 was most resistant to the formation of soluble aggregates in the self-buffered formulation. Increased soluble aggregate levels were observed in all the conventionally buffered (acetate, glutamate, and succinate) formulations, which further increased with increasing buffer strength. The long-term stability of the self-buffered liquid mAb1 formulation (60 mg/mL in 5% sorbitol, 0.01% polysorbate 20, pH 5.2) was comparable to the conventionally buffered (60 mg/mL in 10 mM acetate or glutamate, 5.25% sorbitol, 0.01% polysorbate 20, pH 5.2) formulations. No significant change in pH was observed after 12 months of storage at 37 and 4°C for the self-buffered formulation. The 60 mg/mL self-buffered formulation of mAb1 was also observed to be stable to freeze-thaw cycling (five cycles, ,20°C,,,room temperature). Self-buffered formulations may be a better alternative for the development of high-concentration antibody and protein dosage forms. © 2007 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 97: 3051,3066, 2008 [source] Drying-induced variations in physico-chemical properties of amorphous pharmaceuticals and their impact on stability (I): Stability of a monoclonal antibody,JOURNAL OF PHARMACEUTICAL SCIENCES, Issue 8 2007Ahmad M. Abdul-Fattah Abstract The present study was conducted to investigate the impact of drying method and formulation on the storage stability of IgG1. Formulations of IgG1 with varying levels of sucrose with and without surfactant were dried by different methods, namely freeze drying, spray drying, and foam drying. Dried powders were characterized by thermal analysis, scanning electron microscopy, specific surface area (SSA) analysis, electron spectroscopy for chemical analysis (ESCA), solid state FTIR, and molecular mobility measurements by both isothermal calorimetry and incoherent elastic neutron scattering. Dried formulations were subjected to storage stability studies at 40°C and 50°C (aggregate levels were measured by size exclusion chromatography initially and at different time points). Both drying method and formulation had a significant impact on the properties of IgG1 powders, including storage stability. Among the drying methods, SSA was highest and perturbations in secondary structure were lowest with the spray-dried preparations. Sucrose-rich foams had the lowest SSA and the lowest protein surface accumulation. Also, sucrose-rich foams had the lowest molecular mobility (both fast dynamics and global motions). Stability studies showed a log-linear dependence of physical stability on composition. Preparations manufactured by "Foam Drying" were the most stable, regardless of the stabilizer level. In protein-rich formulations, freeze-dried powders showed the poorest storage stability and the stability differences were correlated to differences in secondary structure. In stabilizer-rich formulations, stability differences were best correlated to differences in molecular mobility (fast dynamics) and total protein surface accumulation. © 2007 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 96:1983,2008, 2007 [source] Hierarchical related regression for combining aggregate and individual data in studies of socio-economic disease risk factorsJOURNAL OF THE ROYAL STATISTICAL SOCIETY: SERIES A (STATISTICS IN SOCIETY), Issue 1 2008Christopher Jackson Summary., To obtain information about the contribution of individual and area level factors to population health, it is desirable to use both data collected on areas, such as censuses, and on individuals, e.g. survey and cohort data. Recently developed models allow us to carry out simultaneous regressions on related data at the individual and aggregate levels. These can reduce ,ecological bias' that is caused by confounding, model misspecification or lack of information and increase power compared with analysing the data sets singly. We use these methods in an application investigating individual and area level sociodemographic predictors of the risk of hospital admissions for heart and circulatory disease in London. We discuss the practical issues that are encountered in this kind of data synthesis and demonstrate that this modelling framework is sufficiently flexible to incorporate a wide range of sources of data and to answer substantive questions. Our analysis shows that the variations that are observed are mainly attributable to individual level factors rather than the contextual effect of deprivation. [source] Free Speech and Multiculturalism In and Out of the AcademyPOLITICAL PSYCHOLOGY, Issue 1 2006Dennis Chong The debate over hate speech in the United States and the accompanying changes in the political culture of the university provides an opportune case to explore the impact of changing norms of free speech on political tolerance toward unpopular groups. I offer a theory of opinion change that identifies the population groups that should be most susceptible to the new norms against hate speech that originated on college campuses around the country in the 1980s. The predictions from this theory are tested using a battery of tolerance items asked repeatedly in General Social Surveys gathered between 1976 and 2000. The analysis shows that the intellectual campaign against hate speech has significantly reduced support for the free speech rights of racists. This retreat in levels of tolerance is most evident among college students who were educated since the mid-1980s, when debates over multiculturalism and political correctness reached their peak. At the same time, levels of tolerance for nonconformist ideas and lifestyles have remained generally high among today's college students and are almost always significantly higher than the national average. The general stability in aggregate levels of tolerance both in the general population and in various demographic groups only serves to highlight the few dramatic changes that have taken place. [source] | |||||||||||||||||||