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African Family (african + family)
Kinds of African Family Selected AbstractsFATHERS, SONS, AND THE STATE: Discipline and Punishment in a Wolof HinterlandCULTURAL ANTHROPOLOGY, Issue 1 2009DONNA L. PERRY ABSTRACT This essay builds on fieldwork in rural Senegal to examine three cases in which elder household heads called on gendarmes to physically discipline rebellious youths. These cases, which revolved around harsh acts of corporal punishment, invite inquiry into common assumptions about African families and states. The first assumption is the common dichotomy drawn between African youths, portrayed as modern and menacing, and African elders, portrayed as "traditional" and hence benign. The second assumption is the dichotomy drawn between the African family, conceived as solidary and nurturing, and the African state, conceived as alien and predatory. In examining these cases of discipline and punishment, this essay reveals the ever-shifting power relations that link Wolof household heads, dependent junior males, and state agents, and simultaneously introduces new questions about the morality of farmer,state relations and generational conflict. My analysis reveals the spatial geography of Senegal's youth crisis, which takes different forms in rural and urban locales. The anxiety of rural patriarchs is fed by a fear-mongering media obsessed with youthful anarchy in the cities, and a long-standing political rhetoric about the threat of rural out-migration. Elder men in the countryside, who experience diminishing household authority under neoliberalism, make proactive efforts to keep the urban youth crisis at bay. They seek to augment their domestic power by reestablishing links with a state that has long bolstered patriarchy but whose power is currently in decline. By lending patriarchs their coercive force, gendarmes attempt to accomplish through private, indirect means, what the postcolonial state is unable to do: maintain social order by reining in disruptive youths. The harsh disciplinary measures that gendarmes employ are not alien to Wolof culture, but integral to Wolof conceptions of child rearing. [source] Novel non-sense GCH1 mutation in a South African family diagnosed with dopa-responsive dystoniaEUROPEAN JOURNAL OF NEUROLOGY, Issue 3 2010S. Bardien Background:, Dopa-responsive dystonia (DRD), a movement disorder characterized by onset in early childhood and a dramatic response to low doses of levodopa, has been shown to be caused by a number of different mutations in the GCH1 gene. Methods:, We identified a South African family which presented with DRD in three family members. Polymerase chain reaction (PCR) primers were designed to span all six exons of GCH1 and the PCR products were screened for pathogenic mutations using direct sequencing. Results:, A novel non-sense mutation (c.233delT; p.I78fsX79) was identified in the DRD patients, which would produce a markedly truncated protein of only 78 amino acids. This mutation was also present in a number of asymptomatic family members. Conclusions:, A novel non-sense mutation in the GCH1 gene can be associated with DRD and reduced penetrance in South African patients. [source] A South African mixed ancestry family with Huntington disease-like 2: Clinical and genetic featuresMOVEMENT DISORDERS, Issue 14 2007Soraya Bardien PhD Abstract Huntington disease-like 2 (HDL2) is a neurodegenerative disorder caused by an expansion of a CTG repeat in the junctophilin-3 gene (JPH3). A limited number of HDL2 families have been reported, all of apparently Black African ancestry. We report on a South African family that presented with progressive dementia and a movement disorder affecting numerous family members. Genotyping of the JPH3 CTG repeat revealed pathogenic expansions in three affected individuals. Whereas HDL2 is thought to be clinically indistinguishable from Huntington disease (HD), 2 of the patients in this study presented with clinical symptoms that differed substantially from HD; one had myoclonus and the other had Parkinsonism. Moreover, brain magnetic resonance imaging scans of these patients showed imaging features atypical for HD. Mitochondrial DNA and Y-chromosome DNA analysis on a family member showed that his maternal and paternal ancestries are typical of that found among the South African mixed ancestry or colored population. A difference in the distribution of CTG repeats between Caucasian and Black individuals was detected. We conclude that the phenotype of HDL2 is broad and can differ from that of typical HD. The diagnosis therefore should be considered in a wide spectrum of neuropsychiatric and abnormal movement presentations. © 2007 Movement Disorder Society [source] A novel nonsense mutation in the EYA1 gene associated with branchio-oto-renal/branchiootic syndrome in an Afrikaner kindredCLINICAL GENETICS, Issue 1 2006JC Clarke Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder characterized by the associations of hearing loss, branchial arch defects and renal anomalies. Branchiootic (BO) syndrome is a related disorder that presents without the highly variable characteristic renal anomalies of BOR syndrome. Dominant mutations in the human homologue of the Drosophila eyes absent gene (EYA1) are frequently the cause of both BOR and BO syndromes. We report a South African family of Afrikaner descent with affected individuals presenting with pre-auricular abnormalities and either hearing loss or bilateral absence of the kidneys. Genetic analysis of the pedigree detected a novel EYA1 heterozygous nonsense mutation in affected family members but not in unaffected family members or a random DNA panel. Through mutational analysis, we conclude that this particular mutation is the cause of BOR/BO syndrome in this family as a result of a truncation of the EYA1 protein that ablates the critical EYA homologous region. To the best of our knowledge, this is the first case of BOR/BO syndrome reported in Africa or in those of the Afrikaner descent. [source] | ||||||||||