Home  About us  Contact
 

Enantioselective Michael Reactions (enantioselective + michael_reaction)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Enantioselective Michael Reaction of ,-Keto Esters Organocatalyzed by Recoverable Cinchona-Derived Dimeric Ammonium Salts.

CHEMINFORM, Issue 22 2010
Silvia Tari
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Cu(I) Tol-BINAP-Catalyzed Enantioselective Michael Reactions of Grignard Reagents and Unsaturated Esters.

CHEMINFORM, Issue 23 2007
Shun-Yi Wang
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

1,2-syn-Selective and Enantioselective Michael Reactions of Acyclic Enones with a Propionate-Derived Nucleophile Catalyzed by Oxazaborolidinone.

CHEMINFORM, Issue 3 2006
Toshiro Harada
No abstract is available for this article. [source]

Enantioselective Michael Addition of Aromatic Ketones to Nitroolefins Catalyzed by Bifunctional Thioureas and Mechanistic Insight

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 4 2010
Bai-Lin Li
Abstract A highly enantioselective Michael reaction of aromatic ketones with nitroolefins was accomplished in the presence of a chiral bifunctional primary amine,thiourea catalyst and 4-nitrobenzoic acid as the co-catalyst; the corresponding adducts were obtained in excellent enantioselectivities (up to 99,%,ee) and yields (up to 98,%). The catalytic mechanism of the Michael reaction was confirmed through the ESI-MS detection of proposed reaction intermediates and the 1H NMR detection of hydrogen bonding between thiourea and the nitroolefins. DFT calculations showed that chiral moieties of the thiourea impacted the yields and enantioselectivities of the adducts remarkably, which corresponds to the observed experimental results. [source]