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Enantioselective Mannich Reaction (enantioselective + mannich_reaction)
Selected AbstractsAsymmetric Synthesis of ,,,-Diaminophosphonic Acid Derivatives with a Catalytic Enantioselective Mannich ReactionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14-15 2009Robert Djiokeng Momo Abstract Optically active ,,,-diaminophosphonic acid derivatives were obtained from the catalytic enantioselective Mannich reaction of phosphoglycine Schiff bases with N -Boc-imines, generated in situ from ,-amido sulfones. [source] Phase-Transfer-Catalyzed Enantioselective Mannich Reaction of Malonates with ,-Amido SulfonesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 15 2006Francesco Fini Abstract The highly enantioselective reaction between in situ generated, Cbz-protected azomethines and malonates in the presence of 150 mol,% of potassium carbonate (50,% w/w) and 1 mol,% of quinine-derived quaternary ammonium bromides as phase-transfer organocatalysts has been developed. This study reports a novel approach for the asymmetric Mannich-type reaction and a wide range of azomethines, including those derived from enolizable aldehydes, is tolerated by the present system. The adducts, obtained in excellent yields with ee up to 98,%, are suitable precursors of optically pure ,-amino acids. [source] Tandem Metal and Organocatalysis in Sequential Hydroformylation and Enantioselective Mannich ReactionsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2009Serghei Chercheja Abstract Metal-catalysed hydroformylation is successfully combined with an organocatalysed stereoselective Mannich reaction in a tandem reaction sequence. This novel type of "tandem catalysis" allows access to complex molecular systems with high levels of enantioselectivity, using simple starting materials and an amino acid as the chiral catalyst. [source] ChemInform Abstract: Enantioselective Mannich Reactions with the Practical Proline Mimetic N-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide.CHEMINFORM, Issue 30 2009Hua Yang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Asymmetric Synthesis of ,,,-Diaminophosphonic Acid Derivatives with a Catalytic Enantioselective Mannich ReactionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14-15 2009Robert Djiokeng Momo Abstract Optically active ,,,-diaminophosphonic acid derivatives were obtained from the catalytic enantioselective Mannich reaction of phosphoglycine Schiff bases with N -Boc-imines, generated in situ from ,-amido sulfones. [source] Organocatalytic Asymmetric Synthesis of Protected ,,,-Diamino AcidsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 17 2009Zugui Shi Abstract In the presence of the readily available quinine-derived catalyst 4d, highly diastereo- and enantioselective Mannich reactions of tosyl-protected imines and ,-isothiocyanato imides proceeded to afford the protected ,,,-diamino acids, useful building blocks for natural products and biologically active compounds, in good to excellent yields. [source] | ||||||||||