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Emerging Applications (emerging + application)

Distribution by Scientific Domains
Chemistry30%
Polymers and Materials Science20%
Medical Sciences20%

Selected Abstracts

Assessment of the Vascularity of a Left Atrial Mass Using Myocardial Perfusion Contrast Echocardiography

ECHOCARDIOGRAPHY, Issue 5 2008
Sahar S. Abdelmoneim M.D. M.Sc.
Emerging applications of myocardial contrast echocardiography (MCE) include the evaluation of myocardial perfusion, the improvement of the definition of intracavitary structures, and evaluation of the relative perfusion of a cardiac mass. We present a case of a patient that was found incidentally to have a cardiac mass on transthoracic echocardiography. MCE was used to evaluate the vascularity of the mass. This case is compared with another patient with a left atrial thrombus, which represents an "avascular" cardiac mass by MCE. [source]

The Synthesis and Assembly of Polymeric Microparticles Using Microfluidics

ADVANCED MATERIALS, Issue 41 2009
Dhananjay Dendukuri
Abstract The controlled synthesis of micrometer-sized polymeric particles bearing features such as nonspherical shapes and spatially segregated chemical properties is becoming increasingly important. Such particles can enable fundamental studies on self-assembly and suspension rheology, as well as be used in applications ranging from medical diagnostics to photonic devices. Microfluidics has recently emerged as a very promising route to the synthesis of such polymeric particles, providing fine control over particle shape, size, chemical anisotropy, porosity, and core/shell structure. This progress report summarizes microfluidic approaches to particle synthesis using both droplet- and flow-lithography-based methods, as well as particle assembly in microfluidic devices. The particles formed are classified according to their morphology, chemical anisotropy, and internal structure, and relevant examples are provided to illustrate each of these approaches. Emerging applications of the complex particles formed using these techniques and the outlook for such processes are discussed. [source]

Survey of the year 2000 commercial optical biosensor literature

JOURNAL OF MOLECULAR RECOGNITION, Issue 5 2001
Rebecca L. Rich
Abstract We have compiled a comprehensive list of the articles published in the year 2000 that describe work employing commercial optical biosensors. Selected reviews of interest for the general biosensor user are highlighted. Emerging applications in areas of drug discovery, clinical support, food and environment monitoring, and cell membrane biology are emphasized. In addition, the experimental design and data processing steps necessary to achieve high-quality biosensor data are described and examples of well-performed kinetic analysis are provided. Copyright © 2001 John Wiley & Sons, Ltd. [source]

Painting and Printing Living Bacteria: Engineering Nanoporous Biocatalytic Coatings to Preserve Microbial Viability and Intensify Reactivity

BIOTECHNOLOGY PROGRESS, Issue 1 2007
Michael C. Flickinger
Latex biocatalytic coatings containing ,50% by volume of microorganisms stabilize, concentrate and preserve cell viability on surfaces at ambient temperature. Coatings can be formed on a variety of surfaces, delaminated to generate stand-alone membranes or formulated as reactive inks for piezoelectric deposition of viable microbes. As the latex emulsion dries, cell preservation by partial desiccation occurs simultaneously with the formation of pores and adhesion to the substrate. The result is living cells permanently entrapped, surrounded by nanopores generated by partially coalesced polymer particles. Nanoporosity is essential for preserving microbial viability and coating reactivity. Cryo-SEM methods have been developed to visualize hydrated coating microstructure, confocal microscopy and dispersible coating methods have been developed to quantify the activity of the entrapped cells, and FTIR methods are being developed to determine the structure of vitrified biomolecules within and surrounding the cells in dry coatings. Coating microstructure, stability and reactivity are investigated using small patch or strip coatings where bacteria are concentrated 102 - to 103 -fold in 5,75 ,m thick layers with pores formed by carbohydrate porogens. The carbohydrate porogens also function as osmoprotectants and are postulated to preserve microbial viability by formation of glasses inside the microbes during coat drying; however, the molecular mechanism of cell preservation by latex coatings is not known. Emerging applications include coatings for multistep oxidations, photoreactive coatings, stabilization of hyperthermophiles, environmental biosensors, microbial fuel cells, as reaction zones in microfluidic devices, or as very high intensity (>100 g·L -1 coating volume·h -1) industrial or environmental biocatalysts. We anticipate expanded use of nanoporous adhesive coatings for prokaryotic and eukaryotic cell preservation at ambient temperature and the design of highly reactive "living" paints and inks. [source]

Bifunctional Eu3+ -doped Gd2O3 nanoparticles as a luminescent and T1 contrast agent for stem cell labeling

CONTRAST MEDIA & MOLECULAR IMAGING, Issue 2 2010
Zhilong Shi
Abstract Magnetic resonance tracking of stem cells has recently become an emerging application for investigating cell,tissue interactions and guiding the development of effective stem cell therapies for regeneration of damaged tissues and organs. In this work, anionic Eu3+ -doped Gd2O3 hybrid nanoparticles were applied as a contrast agent both for fluorescence microscopy and T1 -weighted MRI. The nanoparticles were synthesized through the polyol method and further modified with citric acid to obtain anionic nanoparticles. These nanoparticles were internalized into human mesenchymal stem cells (hMSCs) as confirmed by confocal laser scanning microscopy and quantified by inductively coupled plasma,mass spectrometry. MTT assay of the labeled cells showed that the nanoparticles did not possess significant cytotoxicity. In addition, the osteogenic, adipogenic and chondrogenic differentiation of the hMSCs was not influenced by the labeling process. With MRI, the in vitro detection threshold of cells after incubation with nanoparticles at a Gd concentration of 0.5,mMfor 2,h was estimated to be about 10 000 cells. The results from this study indicate that the biocompatible anionic Gd2O3 nanoparticles doped with Eu3+ show promise both as a luminescent and T1 contrast agent for use in visualizing hMSCs. Copyright © 2010 John Wiley & Sons, Ltd. [source]

A new mixed finite element method for poro-elasticity

INTERNATIONAL JOURNAL FOR NUMERICAL AND ANALYTICAL METHODS IN GEOMECHANICS, Issue 6 2008
Maria Tchonkova
Abstract Development of robust numerical solutions for poro-elasticity is an important and timely issue in modern computational geomechanics. Recently, research in this area has seen a surge in activity, not only because of increased interest in coupled problems relevant to the petroleum industry, but also due to emerging applications of poro-elasticity for modelling problems in biomedical engineering and materials science. In this paper, an original mixed least-squares method for solving Biot consolidation problems is developed. The solution is obtained via minimization of a least-squares functional, based upon the equations of equilibrium, the equations of continuity and weak forms of the constitutive relationships for elasticity and Darcy flow. The formulation involves four separate categories of unknowns: displacements, stresses, fluid pressures and velocities. Each of these unknowns is approximated by linear continuous functions. The mathematical formulation is implemented in an original computer program, written from scratch and using object-oriented logic. The performance of the method is tested on one- and two-dimensional classical problems in poro-elasticity. The numerical experiments suggest the same rates of convergence for all four types of variables, when the same interpolation spaces are used. The continuous linear triangles show the same rates of convergence for both compressible and entirely incompressible elastic solids. This mixed formulation results in non-oscillating fluid pressures over entire domain for different moments of time. The method appears to be naturally stable, without any need of additional stabilization terms with mesh-dependent parameters. Copyright © 2007 John Wiley & Sons, Ltd. [source]

Small-scale free surface flows with breakup: Drop formation and emerging applications

AICHE JOURNAL, Issue 9 2002
Osman A. Basaran
First page of article [source]

Processing Routes to Macroporous Ceramics: A Review

JOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 6 2006
André R. Studart
Macroporous ceramics with pore sizes from 400 nm to 4 mm and porosity within the range 20%,97% have been produced for a number of well-established and emerging applications, such as molten metal filtration, catalysis, refractory insulation, and hot gas filtration. These applications take advantage of the unique properties achieved through the incorporation of macropores into solid ceramics. In this article, we review the main processing routes that can be used for the fabrication of macroporous ceramics with tailored microstructure and chemical composition. Emphasis is given to versatile and simple approaches that allow one to control the microstructural features that ultimately determine the properties of the macroporous material. Replica, sacrificial template, and direct foaming techniques are described and compared in terms of microstructures and mechanical properties that can be achieved. Finally, directions to future investigations on the processing of macroporous ceramics are proposed. [source]

Next-generation transport systems: 4th generation MSPPS

BELL LABS TECHNICAL JOURNAL, Issue 2 2006
James A. Kraeutler
Demand for Ethernet services is increasing exponentially worldwide. Improvements such as generic framing procedure (GFP) and virtual concatenation (VCAT) have been introduced, increasing the efficiency of synchronous optical network/synchronous digital hierarchy (SONET/SDH) transport for packet traffic. The growing volume of packet traffic necessitates further refinement of transport networking techniques toward a more packet-centric model that incorporates increased efficiency in handling packet traffic, and more packet-friendly optical networks; for example, multiprotocol label switching (MPLS) and generalized multiprotocol label switching (GMPLS) enabled networks. The most effective next-generation of multi-service provisioning platforms (MSPPs) must account for these realities and provide a solution for both bandwidth utilization and management capabilities while constituting a platform that can scale from last-mile access to metro core networks. These platforms should incorporate packet-based technologies including MPLS to provide a flexible and cost-effective mix of multi-service traffic engineering and encapsulation techniques, quality of service (QoS), security, and resiliency to providers competing in an increasingly packet-centric market. This paper explains how new transport systems are using novel architectures and exploiting new technologies to support emerging applications with network architectures best suited to the changing characteristics of the traffic they are required to carry. © 2006 Lucent Technologies Inc. [source]

A New, Yet Familiar, Lamellar Zeolite

CHEMCATCHEM, Issue 3 2010
Michael Tsapatsis Prof.
Compulsive layers: Lamellar zeolites are crystalline layered materials with porosity within the layers. A recent breakthrough regarding the synthesis of a new lamellar zeolite with the well-known ZSM-5 structure is highlighted in light of previous work on lamellar zeolites and the emerging applications of hierarchical zeolites and zeolitic layers, which include heterogeneous catalysis and zeolite membranes. [source]