ELECTROPHORESIS, Issue 23 2009
Article first published online: 3 DEC 200
Issue no. 23 has 18 contributions 11 of which have a "Focus on Non-Gel Proteomics" while the remaining 7 articles are concerned with "Gel-Based Proteomics". Part I assembles contributions on non-gel proteomics, and "provide the reader of ELECTROPHORESIS with a perspective of the current trends and innovative developments in proteomic separation methods and technologies" that are based on capillary and microchip formats. Part II consists of articles dealing with methodologies and applications of gel-based proteomics. This is expected to allow the reader to compare the effectiveness of both proteomics approaches. [source]

Cover Picture: Electrophoresis S1'09

ELECTROPHORESIS, Issue S1 2009
Article first published online: 10 JUN 200
This supplement Issue is to celebrate the 30th Anniversary of ELECTROPHORESIS. It consists of 26 contributions by experts in the field, and covering various aspects of electrophoresis, genomics, proteomics and microfluidics. The contributions have the character of review articles and cover relevant topics that were selected by considering high-impact milestone papers which have been published in the journal. [source]

Cover Picture: Electrophoresis 8/2008

ELECTROPHORESIS, Issue 8 2008
Article first published online: 17 APR 200
Regular issues provide a wide range of research and review articles covering all aspects of electrophoresis. Here you will find cutting-edge articles on methods and theory, instrumentation, nucleic acids, CE and CEC, miniaturization and microfluidics, proteomics and two-dimensional electrophoresis. On April 2 Professor Hjertén celebrated his 80th birthday, and it is an honor to take this opportunity to congratulate him on this special occasion and at the same time on his fruitful work. Stellan Hjertén's distinguished personality in research and life makes this celebration very special. It is therefore appropriate to devote a separate laudation in ELECTROPHORESIS to his achievements through which he has attained renown within the separation science community: indeed, he is considered undoubtedly to be the "Father of Capillary Electrophoresis". Professor Hjertén's preliminary work with Arne Tiselius motivated him to commit his career to electrophoresis: the development of free zone electrophoresis certainly revolutionized separation science, and since the construction of the first "capillary electrophoresis" equipment, one of the most cited works in this field carries his name. His friends were very keen to contribute manuscripts to this Issue, covering almost all areas in which Professor Hjertén has worked in his distinguished career. [source]

Evaluation of systemic oxidative status and mononuclear leukocytes DNA damage in children with caustic esophageal stricture

DISEASES OF THE ESOPHAGUS, Issue 4 2006
M. Kaya
SUMMARY., Esophageal stricture (ES) due to accidentally caustic digestions is a common problem in children. Mucosal damage and repeated dilatations lead to chronic inflammation and finally ES. We investigated the oxidative status and DNA damage of children with ES. Five children with ES were compared with the same age- and sex-matched healthy subjects. Oxidative status of plasma was evaluated by measuring myeloperoxidase (MPO) activity, and total peroxide (TP) level. Anti-oxidative status of the plasma was evaluated by measuring catalase (CAT) activity, and total antioxidant response (TAR). We used the Single Cell Gel Electrophoresis (also called Comet Assay) to measure DNA strand break in peripheral blood mononuclear leukocytes. Mean MPO activity and TP levels in the ES group were significantly higher than the control group (0.83 ± 0.35, 0.09 ± 0.03 and 0.98 ± 0.38, 0.34 ± 0.20, P = 0.009 and P = 0.047 respectively). There was no significant difference in CAT activity and TAR levels between the two groups (P = 0.347). DNA damage in patients with ES was increased compared to control subjects (108.8 ± 51.2 and 57.6 ± 31.2 arbitrary units, respectively), but this difference was not significant statistically (P= 0.09). This study shows that systemic oxidative stress and alteration at the nuclear level occur in patients with ES, as a result of multiple dilatations and tissue injury. On the other hand, these results support that patients with ES may benefit from antioxidant treatment. [source]

Comparison of the Electrochemical Behavior of the High Molecular Mass Cadmium Proteins in Arabidopsis thaliana and in Vegetable Plants on Using Preparative Native Continuous Polyacrylamide Gel Electrophoresis (PNC-PAGE)

ELECTROANALYSIS, Issue 1 2006
Bernd Kastenholz
Abstract In Arabidopsis cytosol (supernatant) and in supernatants of vegetable plants high molecular mass cadmium proteins with molecular mass 200,kDa were isolated by using preparative native continuous polyacrylamide gel electrophoresis (PNC-PAGE). Because of a different electrochemical behavior of the Cd proteins in Arabidopsis and endive supernatants on using the same PAGE method, it is concluded that the high molecular mass cadmium proteins of Arabidopsis and endive possess different isoelectric points. Consequently, different chemical structures of the Cd proteins with molecular mass 200,kDa are present in Arabidopsis thaliana and in endive. During the electrophoretic separation of vegetable metalloproteins by using the Model 491 Prep Cell from BioRad, electroanalytical processes like electrode reactions may play an important role. [source]

Coupling Capillary Electrophoresis and Pulsed Electrochemical Detection

ELECTROANALYSIS, Issue 13 2005
Carlos
Abstract Pulsed electrochemical detection (PED) is an excellent method for detection of analytes that normally foul electrodes. In PED, the detection electrode is first cleaned at a high positive potential, then reactivated at a negative potential dissolving the surface oxide, and finally used to oxidize the analyte at a moderate positive potential. Due to the advantages and versatility of PED, many different variations of the detection waveform can be found in literature. This review focuses on application of PED to CE and in particular, the most commonly used modes: pulsed amperometric detection (PAD) and integrated pulsed amperometric detection (iPAD). [source]

Contactless Conductivity Detection in Capillary Electrophoresis: A Review

ELECTROANALYSIS, Issue 24 2004
Pavel Kubá
Abstract The popularity of contactless conductivity detection in capillary electrophoresis has been growing steadily over the last few years. Improvements have been made in the design of the detector in order to facilitate its handling, to allow easy incorporation into available instruments or to achieve higher sensitivity. The understanding of its fundamental working principles has been advanced and the detection approach has also been transferred to lab-on-chip devices. The range of applications has been extended greatly from the initial work on small inorganic ions to include organic species and biomolecules. Concurrent determination of cations and anions by dual injection from opposite ends has been demonstrated as well as sample introduction by using flow-injection systems for easy automation of the process. [source]

Determination of Reserpine in Urine by Capillary Electrophoresis with Electrochemiluminescence Detection

ELECTROANALYSIS, Issue 3 2004
Weidong Cao
Abstract A fast and sensitive approach to detect reserpine in urine using micellar electrokinetic capillary chromatography with electrochemiluminescence (ECL) of Ru(bpy)32+ detection is described. Using a 25,,m i.d. capillary as separation column, the ECL detector was coupled to the capillary in the absence of an electric field decoupler. Field-amplified injection was used to minimize the effect of ionic strength in the sample and to achieve high sensitivity. In this way, the sample was analyzed directly without any pretreatment. The method was validated for reserpine in the urine over the range of 1×10,6,1×10,4,mol/L with a correlation coefficient of 0.996. The RSD for reserpine at a level of 5,,mol/L was 4.3%. The LOD (S/N=3) was estimated to be 7.0×10,8,mol/L. The average recoveries for 10,,mol/L reserpine spiked in human urine were 94%. [source]

Cover Picture: Electrophoresis 19'2010

ELECTROPHORESIS, Issue 19 2010
Article first published online: 29 SEP 2010
Issue no. 19 is a special issue on "CE and CEC Innovations" comprising 1 Fast Track manuscript and 20 manuscripts distributed over 5 separate parts. Part I has 5 research articles on novel trends in CEC. Part II has 4 research articles dealing with innovative methodologies. Part III reports a variety of interactive CE systems described in 5 research articles. Proteins and biomarkers are treated in 3 research articles making up part IV. The last 3 articles in this issue (Part V) are on detection approaches. The FAST TRACK article describes "An automated capillary electrophoresis system for high speed separation of DNA fragments based on a short capillary". [source]

Cover Picture: Electrophoresis 18'2010

ELECTROPHORESIS, Issue 18 2010
Article first published online: 20 SEP 2010
Issue no. 18 is a special issue on "Miniaturization in Asia-Pacific" comprising 21 manuscripts distributed over 5 separate parts. Part I has 1 review article on microfluidics gradient platform for controlling cellular behavior. Part II has 6 research articles dealing with various basic technologies in microfluidics. Part III reports a variety of detection approaches described in 6 research articles. DNA and protein analysis using microfluidics are treated in 3 research articles making up part IV. The last 5 articles in this issue (Part V) are on cell analysis. [source]

Cover Picture: Electrophoresis 16'2010

ELECTROPHORESIS, Issue 17 2010
Article first published online: 7 SEP 2010
Issue no. 17 is a regular issue comprising 18 manuscripts distributed over 5 separate parts. Part I has 7 research articles on some aspects of proteins and cell separations. Part II has 3 research articles on nucleic acid research including cloning/amplification, gene regulation and STR analysis. Part III offers ways of measuring diffusion and binding constants in two separate articles. Concentration and detection approaches are treated in 4 research articles making up Part IV. The last two articles in this issue (Part V) are on CEC and EKC describing a mixed mode monolithic stationary phase and a cyclodextrin-modified MEEKC. Featured articles include: Lamp-based wavelength-resolved fluorescence detection for protein capillary electrophoresis: Set-up and detector performance ((doi: 10.1002/elps.201000246)) Electromigration diffusivity spectrometry: A way for simultaneous determination of diffusion coefficients from mixed samples ((doi: 10.1002/elps.201000252)) Sample stacking capillary electrophoretic microdevice for highly sensitive mini Y short tandem repeat genotyping ((doi: 10.1002/elps.201000270)) [source]

Cover Picture: Electrophoresis 16'2010

ELECTROPHORESIS, Issue 16 2010
Article first published online: 19 AUG 2010
Issue no. 16 is a regular issue with an Emphasis on "Proteins and Proteomics" comprising 20 manuscripts distributed over 4 separate parts. Part I has 7 research articles on various aspects of proteins and proteomics including combinatorial peptide ligand library for accessing low abundance proteins, analysis of membrane proteins, proteomic profiling of human colon cancer cells, quantitative determinations of biomarkers in clinical diagnostics, recombinant factor VIII, analysis of E. coli soluble proteins, and a weakly basic amino-reactive fluorescent label for IEF of proteins and chip electrophoresis. Part II has 2 research articles dealing with the CE analysis of magnetic nanoparticles and a microfluidic magnetic bead impact for cell stimulation. Part III consists of 2 research articles dealing with on-line preconcentration in CE. Instrumentation, devices and various methodologies are described in 9 research articles, which make the content of Part IV. Featured articles include: Combinatorial peptide ligand library plasma treatment: Advantages for accessing low-abundance proteins ((doi: 10.1002/elps.201000188)) Precautions to improve the accuracy of quantitative determinations of biomarkers in clinical diagnostics ((doi: 10.1002/elps.201000243)) Rapid identification of Candida albicans in blood by combined capillary electrophoresis and fluorescence in situ hybridization ((doi: 10.1002/elps.201000138)) [source]

Cover Picture: Electrophoresis 14'2010

ELECTROPHORESIS, Issue 14 2010
Article first published online: 21 JUL 2010
Issue no. 14 is a "mini special issue" on "Microscale Separation Methods for Metabolomics" comprising 9 manuscripts on metabolomics and 12 manuscripts on various topics in nucleic acids, biomarkers, proteomics, miniaturization, etc. Part I has 9 manuscripts on metabolomics featuring new technological developments and the potential of CE-MS, targeted analysis of one class of metabolites and non-targeted analysis, and data interpretation that is essential to acquire useful biological information. In short, the importance of CE and, generally, of microscale separation methods for metabolomics is rapidly increasing and the papers published in this issue give an overview of this field. Part II has 2 research papers on biomarkers while Part III is on various aspects of nucleic acids including but not limited to genotyping, PCR, SSCP, PCR and detection of DNA. Part IV describes various aspects of fundamentals and methodology in microfluidics, cell lysates by 2-DE, CE-LIF of plasmid DNA, whole blood assay of trypsin activity, etc. [source]

Cover Picture: Electrophoresis 13'2010

ELECTROPHORESIS, Issue 13 2010
Article first published online: 30 JUN 2010
Issue no. 13 is a special issue on "Food and Beverage Analysis" comprising 23 contributions distributed over four distinct parts. Part I "presents six review papers, five of them are focused on the use of capillary electromigration techniques for detecting enantiomers, nucleosides, nucleotides, pesticides and contaminants in foods as well as foodborne pathogens". The sixth review deals with the application of two-dimensional electrophoresis to investigate food allergens. A series of original contributions on the use of CE, CEC and MEKC in the analysis of food constituents are grouped in Part II. Part III presents "Works on the detection of genetically modified foods by CGE and the analysis of antibiotics and antioxidants by microemulsion electrokinetic chromatography". Finally, Part IV is on the use of CE-MS to analyze endocrine disruptors and polyphenols in different food matrices, and on the speciation analysis of arsenic and selenium compounds in different foodstuffs by capillary electrophoresis-inductively coupled plasma-mass spectrometry. [source]

Cover Picture: Electrophoresis 12'2010

ELECTROPHORESIS, Issue 12 2010
Article first published online: 18 JUN 2010
Issue no. 12 is a regular issue comprising 19 contributions distributed over five distinct parts. Part I has 7 articles describing novel methodologies pertaining to proteins and proteomics. Part II has 3 research papers on CEC stationary phases and CEC-MS. Part III is on detection approaches including a review article on the advances and applications of chemiluminescence coupled to CE. Part IV has two papers on enantioseparations, and Part V has four contributions on aptamers, human genetic, preparative FFE and microchannels. Featured articles include: Simplified method for concentration of mitochondrial membrane protein complexes ((10.1002/elps.201000019)) Analysis of low-molecular mass aldehydes in drinking waters through capillary electrophoresis with laser-induced fluorescence detection ((10.1002/elps.200900734)) Selection of aptamers for signal transduction proteins by capillary electrophoresis ((10.1002/elps.200900543)) [source]

Cover Picture: Electrophoresis 11'2010

ELECTROPHORESIS, Issue 11 2010
Article first published online: 26 MAY 2010
Issue no. 11 is a special issue on "Bioanalysis" comprising 18 manuscripts distributed over six distinct parts. Part I has 3 review articles describing a novel approach for biopolymer focusing, free flow electrophoresis and mass spectrometry analysis of deamidation of proteins. Part II has 2 research papers on some fundamentals and methodology. Part III is on microRNA while Part IV is on protein and protein complex analysis using CE and microfluidics. Part V, which is on gel based protein analysis and proteomic profiling, has 7 contributions making the bulk of the special issue. Finally, Part VI is on metabolic and toxicological profiling and has 3 contributions. [source]

Cover Picture: Electrophoresis 10'2010

ELECTROPHORESIS, Issue 10 2010
Article first published online: 18 MAY 2010
Issue no. 10 is a regular issue comprising 19 manuscripts distributed over four distinct parts. Part I is on microfluidics and miniaturized systems and has 5 articles; Part II is on nucleic acids with 4 articles on restriction endonuclease fingerprinting, mutation detection and DNA separation and detection; Part III has 7 articles on monolithic stationary phases for CEC, single walled carbon nanohorns as pseudo-stationary phases for CEC and EKC, MEEKC, cyclodextrin-modified gold nanoparticles for enantioseparations by CEC, use of divalent dipeptides as counter ions in CE and capillary coating for CE of proteins; and Part IV has 3 articles on proteomics methodologies. Featured articles include: Microfluidic preparative free-flow isoelectric focusing in a triangular channel: System development and characterization ((10.1002/elps.200900577)) Separation and recovery of nucleic acids with improved biological activity by acid-degradable polyacrylamide gel electrophoresis ((10.1002/elps.200900783)) Evaluation of the performance of single-walled carbon nanohorns in capillary electrophoresis ((10.1002/elps.200900628)) The inter- and intra-operator variability in manual spot segmentation and its effect on spot quantitation in two dimensional electrophoresis analysis. ((10.1002/elps.200900674)) [source]

Cover Picture: Electrophoresis 9'2010

ELECTROPHORESIS, Issue 9 2010
Article first published online: 26 APR 2010
Issue no. 9 is a special issue on "CEC and EKC" comprising one "Fast Track" article and 21 articles distributed over two distinct parts. "Part I groups 13 contributions on enantioseparations in CE, CEC and capillary LC using various chiral selectors and their applications to a wide range of chiral species, while Part II assembles 8 papers on various methodological aspects and applications of EKC, CEC and CE". The "Fast Track" paper describes enhanced selectivity in CZE with multi-chiral selector systems. [source]

Cover Picture: Electrophoresis 8'2010

ELECTROPHORESIS, Issue 8 2010
Article first published online: 20 APR 2010
Issue no. 8 is a regular issue comprising19 manuscripts distributed over four distinct parts. Part I is on proteins and proteomics and has 5 articles; Part II is on nucleic acids with 5 articles on DNA purification, sequencing, genotyping and differential gene expression; Part III has 4 articles on droplet dispensing and particle separation; Part IV is on various methodologies and applications assembling 5 articles on improved sample preparation method for glycan analysis by CE, measurement of intracellular accumulation chemotherapeutic drugs in cancerous cells, metabolic monitoring in microfluidic cell arrays, microchip electrophoresis for continuous monitoring of microdialysis samples, and determination of glyphosate and its metabolites in plant materials by CE. Featured articles include: Delta2D and Proteomweaver: Performance evaluation of two different approaches for two-dimensional electrophoresis analysis. ((10.1002/elps.200900766)) A Multidimensional Electrophoretic System of Separation for the Analysis of Gene Expression (MESSAGE). ((10.1002/elps.200900624)) Particle trapping using dielectrophoretically patterned carbon nanotubes. ((10.1002/elps.200900717)) [source]

Cover Picture: Electrophoresis 7'2010

ELECTROPHORESIS, Issue 7 2010
Article first published online: 26 MAR 2010
Issue no. 7 is a special issue on CE-MS consisting of "19 manuscripts subdivided into three major categories: one devoted to instrumental and methodical advances, two providing an insight into up-to-date applications from the fields of technical and natural products, food and environmental analysis on the one hand and biomedical and pharmaceutical analysis on the other hand. Diverse approaches how CE-MS can be employed for the solution of various analytical problems can be found in these papers. Different modes of electroseparation techniques in the capillary format such as CZE, CEC or MEEKC are coupled to various MS instruments ranging from simple quadrupole MS instruments to state of the art QTOF's, using a range of interfaces such as ESI, ICP or APPI. So this special issue will again try to present an overview of current trends and developments in the fields of CE-MS" [source]

Cover Picture: Electrophoresis 6'2010

ELECTROPHORESIS, Issue 6 2010
Article first published online: 22 MAR 2010
Issue no. 6 is a regular issue consisting of 18 full research papers. The first paper is a "Fast Track" contribution involving microchip electrophoresis of Alu elements for gender determination and inference of human ethnic origin. The remaining 17 papers are distributed over 5 different parts: Part I is on some trends in CEC; Part II deals with enantioseparations; Part III describes some novel detection approaches; Part IV has investigations on proteomics and proteins; Part V tackles the subjects related to pathogens, bacteria and the binding of aptamers to small solutes. [source]

Cover Picture: Electrophoresis 5'2010

ELECTROPHORESIS, Issue 5 2010
Article first published online: 26 FEB 2010
Issue no. 5 is a Special issue on "Fundamentals of Electrophoresis". Part I has 5 review articles on the various fields of electrophoresis. Separation in nano-channels is treated in 3 articles in Part II. Part III has 3 research papers on computer simulation of electromigration and Part IV also has 3 articles on stacking and focusing. Interaction in electrophoretic systems is the subject of Part V which has 6 research papers. Finally, electroosmotic flow is described in 1 paper in part VI. [source]

Cover Picture: Electrophoresis 4'2010

ELECTROPHORESIS, Issue 4 2010
Article first published online: 16 FEB 2010
Issue no. 4 is a regular issue with Emphasis on "Bioanalysis". Part I has 12 articles on bioanalysis featuring methodologies for proteomics, proteins, peptides and nucleic acids. Part II has 5 papers on interactive CE, e.g., MEEKC, MEKC and ACE. The remaining 2 articles make up Part III, and are concerned with the regulation of flow in microfluidics and sensitivity enhancement in CEC. Featured articles include: Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in gel electrophoresis. ((10.1002/elps.200900441.R1)) An effective SCAR-PCR method derived from restriction site amplified polymorphism (RSAP) for the identification of female Schistosoma japonicum of zoonotic significance. ((10.1002/elps.200900615.R1)) Rapid and sensitive DNA targets detection using enzyme amplified electrochemical detection based on microchip. ((10.1002/elps.200900538.R1)) [source]

Cover Picture: Electrophoresis 3'2010

ELECTROPHORESIS, Issue 3 2010
Article first published online: 29 JAN 2010
Issue no. 3 is a regular issue with Emphasis on "Proteins and Proteomics". The first part has 8 articles on proteins and proteomics covering various topics, e.g. preparative divergent flow IEF, multichannel gel electrophoresis, capillary gel electrophoresis, nanoparticle-based CE of proteins, 2-DE in a radial gel format, depletion of high abundance proteins, and proteomic investigation of fetal brain and lentil seed. The remaining 10 articles are concerned with nucleic acids, gene expression, methodologies and application. Featured articles include: Preparative divergent flow IEF without carrier ampholytes for separation of complex biological samples ((10.1002/elps.200900484)) SDS-PAGE and two-dimensional maps in a radial gel format ((10.1002/elps.200900526)) Analysis of Effect of Electrolyte Types on Electrokinetic Energy Conversion in Nanoscale Capillaries ((10.1002/elps.200900409)) A simple method to determine the surface charge in microfluidic channels ((10.1002/elps.200900603)) [source]

Cover Picture: Electrophoresis 2'2010

ELECTROPHORESIS, Issue 2 2010
Article first published online: 18 JAN 2010
Issue no. 2 has 19 contributions including one Fast Track contribution on "Thermophoresis of ssDNA". The remaining 18 articles cover a wide variety of investigation involving nucleic acids, cells, viruses, interactive CE, detection methodologies in CE, enantioseparations, and studies on proteins and proteomics. Further selected articles include: Capillary electrophoresis of bone marrow stromal cells with uptake of heparin-functionalized poly(lactide-co-glycolide) nanoparticles during differentiation towards neurons. ((10.1002/elps.200900336)) Ghrelin-liposome interactions. Characterization of liposomal formulations of an acylated 28-amino acid peptide using capillary electrophoresis. ((10.1002/elps.200900394)) [source]

Cover Picture: Electrophoresis 1'2010

ELECTROPHORESIS, Issue 1 2010
Article first published online: 28 DEC 200
Issue no. 1 has 17 "comprehensive and critical reviews written by experts in the fields of CE and CEC. The six review articles in Part I provide an in-depth description of the latest developments in different methodologies and their applications, e.g. surface modification in microfluidics, determination of binding constants in CE, enhanced sensitivity in chiral CE, coupling SPE-CE, CE and MCE in microdialysis, and electrophoretically mediated microanalysis. Part II reviews CE and CEC of biomolecules such as amino acids, peptides and proteins. Part III is on recent progress made in inorganic species, food, antibiotics, and phytochemical analyses and forensic sciences." [source]

Recent advances in the application of capillary electromigration methods for food analysis and Foodomics

ELECTROPHORESIS, Issue 1 2010
Miguel Herrero
Abstract The use of capillary electromigration methods to analyze foods and food components is reviewed in this work. Papers that were published during the period April 2007 to March 2009 are included following the previous review by García-Cañas and Cifuentes (Electrophoresis, 2008, 29, 294,309). These works include the analysis of amino acids, biogenic amines, peptides, proteins, DNAs, carbohydrates, phenols, polyphenols, pigments, toxins, pesticides, vitamins, additives, small organic and inorganic ions and other compounds found in foods and beverages, as well as those applications of CE for monitoring food interactions and food processing. The use of microchips, CE-MS, chiral-CE as well as other foreseen trends in food analysis are also discussed including their possibilities in the very new field of Foodomics. [source]

Cover Picture: Electrophoresis 24'2009

ELECTROPHORESIS, Issue 24 2009
Article first published online: 10 DEC 200
Issue no. 24 has 20 contributions on "Miniaturization". This special issue of Miniaturization "features reports on the latest developments in miniaturized systems focused on Instrumentation, Bioanalysis, and Column Technology and Microfluidic Protocols". In addition, the issue presents a Fast Track article describing a microwell array device with integrated microfluidic components for enhanced single-cell analysis. [source]

Cover Picture: Electrophoresis 23'2009

Cover Picture: Electrophoresis 22'2009

ELECTROPHORESIS, Issue 22 2009
Article first published online: 25 NOV 200
Issue no. 22 is a Special Issue on "CE and CEC Innovations" consisting of 24 important contributions in various areas of CE and CEC that are grouped into five different parts. Part I has 7 articles on novel "Stationary Phases for CEC". Part II is on "CE of Microorganisms and their Components and Interactions", and has 4 research articles. "Enantioseparations" constitute part III and has 3 research articles dealing with different chiral species and chiral CE systems. Part IV has 3 contributions on "Detection Approaches in CE". Part V is on "Capillary Coating, Affinity and Separation Media , Applications" and contains 7 research articles dealing with the separations of proteins, lipoproteins, bioactive inflammatory cytokines, inorganic and small organic anions, non-steroidal anti-inflammatory drugs, cell culture media and ancient DNA samples." [source]