Home About us Contact
|
Home About us Contact | ||
|
|
||
Drug Addicts (drug + addict)
Selected AbstractsDrug addicts in therapy,changes in life space in the course of one yearJOURNAL OF COMMUNITY & APPLIED SOCIAL PSYCHOLOGY, Issue 5 2002Marcella Ravenna Abstract In a residential community treatment setting, moods and emotional states of drug addicts were explored over a 1-year period. The specific form of treatment of heroin addiction employed in the communities is based on the importance of interpersonal relationships for psychosocial transition. Twenty-nine participants reported current mood, emotions, attributions, and motive activation using a time-sampling diary for 2 weeks at the beginning of the treatment, and 6 and 12 months later. Results show an increase in positive emotions, and in subjective strength and freedom. Furthermore, participants report higher self-esteem and use less fatalistic attributions. This is interpreted as indicating successful transition processes in terms of higher autonomy, a more extended life space and increased levels of realism. Copyright © 2002 John Wiley & Sons, Ltd. [source] FS09.1 Diacetylmorphine (heroin) allergyCONTACT DERMATITIS, Issue 3 2004Aliet J Hogen Esch Since heroin is delivered to a selected group of drug addicts under supervision of nurses in the Netherlands, we reported about several nurses who presented with work-related eczema and positive patch tests to heroin. To investigate the prevalence of heroin contact allergy among all workers in this heroin delivery project, a study was started using questionnaires. Altogether 31 nurses reported work-related complaints out of 100 who returned questionnaires. Besides reports of eczema, mainly of eyelids (probably airborne) and hands, there were mucosal and respiratory complaints. Patch tests were performed in 25 nurses with complaints; in 9 of them a heroin contact allergy could be confirmed. In 6 out of these 9 nurses this was combined with mucosal or respiratory complaints. There were also 6 nurses with mucosal or respiratory complaints without a contact allergy. Contact dermatitis from opioids, such as morphine and codeine, has been documented among opioid industry workers, nurses, doctors, pharmacists, and in patients. In conclusion heroin appears to be a potent contact allergen, causing contact dermatitis. Mucosal and respiratory complaints however, cannot be explained by this contact allergy; they might be caused by a type-1-allergy to heroin, or by a direct histamine liberating effect. Opioids are known histamine liberators causing urticaria, rhinitis and anaphylactoid reactions; therefore intracutaneous tests with heroin are unreliable. In an ongoing research project it will be attempted to detect specific IgE to heroin in the 12 workers with mucosal or respiratory complaints; within the next few months results will be available. [source] Puffy hand syndrome due to drug addiction: a case,control study of the pathogenesisADDICTION, Issue 9 2006Valérie Andresz ABSTRACT Aim We studied the pathogenesis of puffy hand syndrome of intravenous drug use. We hypothesized that injections of high-dose sublingual buprenorphine, instead of the recommended sublingual administration, could play an important role in lymphatic obstruction and destruction. Design and participants We set up a case,control study in substitution centres, recruiting intravenous drug addicts with and without puffy hands, respectively. The subjects were asked to answer anonymously a questionnaire of 40 items comprising social and demographic status, history of illicit drugs use, buprenorphine misuse and injection practices. Findings We included 33 cases and 33 controls, mean age of 34 years. They were past heroin users, mainly methadone-substituted. In multivariate analysis, sex (women) (OR = 8.9, P = 0.03), injections in the hands (OR = 5.9, P = 0.03), injections in the feet (OR = 6.5, P = 0.01) and the absence of tourniquet (OR = 7.0, p = 0.02) were significant risk factors for puffy hand syndrome. In 69.7% of the cases and 59.4% of the controls, respectively, there was a high-dose sublingual buprenorphine misuse, although it appeared not to be a significant risk factor for puffy hand syndrome. Conclusions Injection practices are likely to cause puffy hands syndrome, but buprenorphine misuse should not be considered as a significant risk factor. However, intravenous drug users must still be warned of local and systemic complications of intravenous drug misuse. [source] Nurses' perception of the quality of care they provide to hospitalized drug addicts: Testing the Theory of Reasoned ActionINTERNATIONAL JOURNAL OF NURSING PRACTICE, Issue 6 2009Merav Ben Natan PhD RN A correlational design was used to examine nursing staff attitudes and subjective norms manifested in intended and actual care of drug users based on the Theory of Reasoned Action. One hundred and thirty-five nursing staff from three central Israeli hospitals completed a questionnaire examining theory-based variables as well as sociodemographic and professional characteristics. Most respondents reported a high to very high level of actual or intended care of drug users. Nurses' stronger intentions to provide quality care to drug users were associated with more positive attitudes. Nursing staff members had moderately negative attitudes towards drug users. Nurses were found to hold negative stereotypes of drug addict patients and most considered the management of this group difficult. Positive attitudes towards drug users, perceived expectations of others and perceived correctness of the behaviour are important in their effect on the intention of nurses to provide high-quality care to hospitalized patients addicted to drugs. [source] Drug addicts in therapy,changes in life space in the course of one yearJOURNAL OF COMMUNITY & APPLIED SOCIAL PSYCHOLOGY, Issue 5 2002Marcella Ravenna Abstract In a residential community treatment setting, moods and emotional states of drug addicts were explored over a 1-year period. The specific form of treatment of heroin addiction employed in the communities is based on the importance of interpersonal relationships for psychosocial transition. Twenty-nine participants reported current mood, emotions, attributions, and motive activation using a time-sampling diary for 2 weeks at the beginning of the treatment, and 6 and 12 months later. Results show an increase in positive emotions, and in subjective strength and freedom. Furthermore, participants report higher self-esteem and use less fatalistic attributions. This is interpreted as indicating successful transition processes in terms of higher autonomy, a more extended life space and increased levels of realism. Copyright © 2002 John Wiley & Sons, Ltd. [source] Diary reports on emotional experiences in the onset of a psychosocial transition: becoming drug-freeJOURNAL OF COMMUNITY & APPLIED SOCIAL PSYCHOLOGY, Issue 1 2001Marcella Ravenna Abstract The process of becoming drug free is viewed as a psychosocial transition in the life of drug addicts. A specific form of treatment of heroin addiction within residential communities is based on the importance of interpersonal relationships for change. Well-being of 65 drug addicts during the first 2 weeks in a residential community is explored using a time-sampling diary which was completed four times a day. The influence of subjects' history, situational context, and motive activation on well-being and emotions is investigated. Results show that well-being and emotions differ mainly according to subjects' history, but not , at least at the beginning of treatment within the community , according to situations. This is interpreted as a ,state of shock' in the new environment and highlights the necessity for special individual care for subjects with a long drug career. Copyright © 2001 John Wiley & Sons, Ltd. [source] High-Alcohol Preferring Mice Are More Impulsive Than Low-Alcohol Preferring Mice as Measured in the Delay Discounting TaskALCOHOLISM, Issue 7 2009B. G. Oberlin Background:, Repeated studies have shown that high impulsivity, when defined as the tendency to choose small immediate rewards over larger delayed rewards, is more prevalent in drug addicts and alcoholics when compared with nonaddicts. Assessing whether impulsivity precedes and potentially causes addiction disorders is difficult in humans because they all share a history of drug use. In this study, we address this question by testing alcohol-naïve mice from lines showing heritable differences in alcohol intake. Methods:, Replicated selected lines of outbred high-alcohol preferring (HAP) mice were compared to a low-alcohol preferring (LAP) line as well as the low-drinking progenitor line (HS/Ibg) on an adjusting amount delay discounting (DD) task. The DD task employs 2 levers to present subjects with a choice between a small, immediate and a large, delayed saccharin reward. By adjusting the quantity of the immediate reward up and down based on choice behavior, the task allows an estimate of how the subjective value of the delayed reinforcer decreases as delays increase. Latency to respond was also measured for each trial. Results:, Both HAP2 and HAP1 lines of mice were more impulsive than the LAP2 and HS/Ibg lines, respectively. Hyperbolic curve-fitting confirmed steeper discounting in the high-alcohol drinking lines. In addition, the high-alcohol drinking lines demonstrated greater within-session increases in reaction times relative to the low-alcohol drinking lines. No other differences (consumption of saccharin, total trials completed) consistently mapped onto genetic differences in alcohol drinking. Conclusions:, Alcohol-naïve outbred mice selected for high-alcohol drinking were more impulsive with saccharin reinforcers than low-alcohol drinkers. These data are consistent with results seen using inbred strain descendents of high-alcohol drinking and low-alcohol drinking rat lines, and suggest that impulsivity is a heritable difference that precedes alcoholism. [source] The effect of additives on naltrexone hydrochloride release and solvent removal rate from an injectable in situ forming PLGA implantPOLYMERS FOR ADVANCED TECHNOLOGIES, Issue 5 2006Raheleh Bakhshi Abstract Biodegradable in situ forming drug delivery systems for naltrexone release are promising for post-treatment of drug addicts. The effect of two different additives, glycerol and ethyl heptanoate, on the naltrexone hydrochloride release and solvent removal from a poly(DL -lactide-co-glycolide) (PLGA) injectable implant is presented in this article. The experimental results showed that the in vitro initial release of the drug was decreased in the presence of these additives. Ethyl heptanoate was, however, more effective than glycerol and increasing the amount of additives in PLGA solution up to 5% (w/w) resulted in a decrease of initial naltrexone release rate up to 50%. The morphological evaluation of implants using scanning electron microscopy indicated that the additives generated a less porous structure together with a finger-like to sponge-like transition. The solvent removal profiles of injectable implants, which can be well described by thermogravimetric and morphological analysis, were in good agreement with drug release profiles. Copyright © 2006 John Wiley & Sons, Ltd. [source] Potentials of ion trap collisional spectrometry for liquid chromatography/electrospray ionization tandem mass spectrometry determination of buprenorphine and nor -buprenorphine in urine, blood and hair samplesRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 8 2006Donata Favretto A liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method has been developed for the analysis of buprenorphine (BUP) and nor -buprenorphine (NBUP) in biological fluids. Analytes are isolated from urine and blood, after addition of d4 -buprenorphine (d4 -BUP) as internal standard, by solid-phase extraction. Preparation of hair involves external decontamination, mechanical pulverization, overnight incubation in acidic medium, and neutralization prior to extraction. Enzymatic hydrolysis with , -glucuronidase may be performed to distinguish between free and total BUP. Chromatographic separation is accomplished by gradient elution on a cyanopropyl 2.1,×,150,mm column. Positive ion ESI and MS analyses are carried out in an ion trap mass spectrometer. The use of this mass analyzer allows effective collisional experiments to be performed on ESI-generated MH+ species. Abundant product ions are produced, which can be monitored together with precursor ions without losing sensitivity. Thus, assay selectivity is definitely increased with respect to LC/ESI-MS/MS methods in which only precursor ions are monitored. The method has good linearity (calibration curves were linear in the range 0.1,10,ng/mL in urine and blood, in the range 10,160,pg/mg in hair) and limits of detection of 0.05,ng/mL for both BUP and NBUP in blood and urine samples, of 4,pg/mg for both analytes in hair. Both intra- and inter-assay precision and accuracy were satisfactory at three concentrations studied: relative standard deviations were <13.7% in urine, <17.3% in blood, <17.8% in hair; percent deviation of the mean from the true value was always <10.5% in urine and blood, <16.1% in hair. The method can be used to determine both analytes in the urine and hair of drug addicts on replacement therapy, and in post-mortem blood specimens when there is suspicion of drug-related death. Copyright © 2006 John Wiley & Sons, Ltd. [source] Surfing in the Third Millennium: Commodifying the Visual ArgotTHE AUSTRALIAN JOURNAL OF ANTHROPOLOGY, Issue 3 2002David Lanagan The practice of surfing has often been at odds with the mores of wider society, to the point where surfers have been described in the media as rotten, long-haired, unwashed drug addicts, or as jobless junkies. However, in recent years there has been an increase in the popularity of surfing and an increase in the consumption of surfing related commodities. This increase in popularity is largely due to the marketing practices of the business interests that are involved in surfing, which has appropriated its images and sold them to a rapidly expanding and lucrative market. This paper will outline how the commodification of surfing's visual style, and the meanings that are symbolised by this development, have had a three-fold effect on the sport. First, surfing has been shifted away from the beach into quite different contexts; second, surfing as understood by the wider society has been altered and; third, the commodifying practices of business interests have transferred the symbolic ownership of the sport from surfers to surfing capital. [source] | ||||||||||