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Domino Reaction (domino + reaction)

Distribution by Scientific Domains
Chemistry100%
Distribution within Chemistry
Organic Chemistry82%
General & Introductory Chemistry17%

Kinds of Domino Reaction

  • Catalyze domino reaction
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    Selected Abstracts

    A Versatile Synthesis of Annulated Carbazole Analogs Involving a Domino Reaction of Bromomethylindoles with Arenes/Heteroarenes

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 4 2009
    Vasudevan Dhayalan
    Abstract A ZnBr2 -mediated arylation of aryl/heteroaryl methyl bromides with arenes at 80 °C led to the formation of arylated products, which underwent subsequent 1,5-sigmatropic rearrangement followed by electrocyclization and aromatization with loss of a diethylmalonate unit to afford the corresponding annulated products. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]

    Laccase from Basidiomycetous Fungus Catalyzes the Synthesis of Substituted 5-Deaza-10-oxaflavins via a Domino Reaction

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 4 2009
    Mazaahir Kidwai
    Abstract The present investigation provides a simple and convenient route for the synthesis of substituted 5-deaza-10-oxaflavins owing to their importance as probable redox coenzymes. The reaction of ,,,-unsaturated derivatives of barbituric acid and dimedone with catechol or 1,4-hydroquinones was catalyzed using laccase in aqueous medium. Quinones, generated in situ by the oxidation of the corresponding catechol or 1,4-hydroquinones, underwent a domino reaction with chalcones to produce 5-deaza-10-oxaflavins and tetrahydroxanthen-1-ones. [source]

    Palladium(II)-Catalyzed Domino Reaction of 2-(1-Alkynyl)-2-alken-1-ones with Nucleophiles: Scope, Mechanism and Synthetic Application in the Synthesis of 3,4-Fused Bicyclic Tetrasubstituted Furans

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 4 2009
    Yuanjing Xiao
    Abstract Described herein is the development of a palladium(II)-catalyzed two- or three-component reaction of 2-(1-alkynyl)-2-alken-1-ones with nucleophiles and allylic chlorides. Various types of nucleophiles such as O- , N- , C -based nucleophiles and olefin-tethered O- , N- , C -based nucleophiles were investigated. The scope, mechanism and application of this Pd(II)-catalyzed domino reaction were studied. In these transformations, the palladium catalyst exhibits a dual role, serving simultaneously as a Lewis acid and a transition metal. Two possible reaction pathways (cross-coupling reaction vs. Heck reaction) from the same intermediate furanylpalladium species were observed. The reaction pathway is dependent on the property of the nucleophile and the length of the tethered chain as well. When olefin-tethered O -based nucleophiles were used, only the cross-coupling reaction pathway was observed, in contrast, both reaction pathways were observed when olefin-tethered C -based nucleophiles were employed. The product ratio is dependent on the length of the tethered chain. Furthermore, ring-closing metathesis (RCM) of corresponding furans with CC bonds provides an easy method for the preparation of functionalized oxygen-heterocycles , 3,4-fused bicyclic furans. It is also noteworthy that allylic chloride can be as an oxidant besides its well known function as an alkylating reagent. [source]

    Domino Reaction of Acyclic ,,,-Dialkenoylketene S,S -Acetals and Diamines: Efficient Synthesis of Tetracyclic Thieno[2,3- b]thiopyran-Fused Imidazo[1,2- a]pyridine/Pyrido[1,2- a]pyrimidines

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 14 2006
    Fushun Liang
    Abstract A series of unusual fused tetraheterocyclic compounds 3, consisting of a thiopyran (ring A), a thiophene (ring B), a pyridine (ring C), and an imidazole or a pyrimidine (ring D) core, with a bridgehead nitrogen and an angular methyl group, were successfully synthesized by a catalyst-free, one-pot, two-component domino reaction of 4-(4-methyl-1,3-dithiol-2-ylidene)-1,7-bis(aryl/heteroaryl)hepta-1,6-diene-3,5-dione 2 and diamines. In this reaction, up to five new bonds were formed accompanied by the CS bond cleavage of the 1,3-dithiole ring of 2, with water as the only by-product. [source]

    A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H- Indazoles,

    ANGEWANDTE CHEMIE, Issue 37 2009
    Nis Halland Dr.
    Praktisch und sehr nützlich ist die Reaktion einfach zugänglicher (2-Chlorphenyl)acetylen- und Hydrazinsubstrate, die in wenigen Stunden unter sehr milden Reaktionsbedingungen zu substituierten 2H -Indazolen führt (siehe Schema; DMF=N,N -Dimethylformamid). Die katalysierte Dominosequenz umfasst eine regioselektive Kupplung mit anschließender intramolekularer Hydroaminierung und Isomerisierung der gebildeten exocyclischen Bindung. [source]

    ChemInform Abstract: Unexpected Domino Reaction via Pd-Catalyzed Sonogashira Coupling of Benzimidoyl Chlorides with 1,6-Enynes and Cyclization to Synthesize Quinoline Derivatives.

    CHEMINFORM, Issue 24 2010
    Guo-Lin Gao
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: A General and Mild Palladium-Catalyzed Domino Reaction for the Synthesis of 2H-Indazoles.

    CHEMINFORM, Issue 3 2010
    Nis Halland
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Asymmetric Organocatalytic Four-Component Quadruple Domino Reaction Initiated by Oxa-Michael Addition of Alcohols to Acrolein.

    CHEMINFORM, Issue 48 2009
    Fang-Lin Zhang
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Azirino[c]imidazolyl Ylides in the Domino Reaction of 2,2-Dialkyl-4,6-diaryl-1,3-diazabicyclo[3.1.0]hex-3-enes with Dichlorocarbenes.

    CHEMINFORM, Issue 23 2009
    4-diazabicyclo [4.1.0]hept-2-enes., 5-diaryl-, 6RS)-4- (Alk-1-enyl)-, 7-trichloro-, Synthesis of (1RS
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Multicomponent Domino Reaction Promoted by Mg(ClO4)2: Highly Efficient Access to Functionalized 1,4-Dihydropyridines.

    CHEMINFORM, Issue 50 2008
    Giuseppe Bartoli
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    Triethyl Phosphite Mediated Domino Reaction: Direct Conversion of ,-Nitroalkenes into N-Heterocycles.

    CHEMINFORM, Issue 35 2007
    Elena Merisor
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    A Multicomponent Domino Reaction and in situ Aerobic Oxidation Sequence for the First One-Pot Synthesis of Polycyclic Benzimidazoles from 1,3-Dicarbonyl Derivatives.

    CHEMINFORM, Issue 48 2006
    Frederic Lieby.Muller
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    A Highly Efficient Synthesis of 1,2,3,4-Tetrahydroquinolines by Molecular Iodine Catalyzed Domino Reaction of Anilines with Cyclic Enol Ethers.

    CHEMINFORM, Issue 40 2006
    Xu-Feng Lin
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    Domino Reaction of 2,3-Epoxy-1-alcohols and PIFA in the Presence of H2O and the Concise Synthesis of (+)-Tanikolide.

    CHEMINFORM, Issue 1 2006
    Yasuyuki Kita
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Acid-Catalyzed Condensation of 1,3,5-Triphenylpentane-1,5-dione with Benzaldehyde , A New Domino Reaction.

    CHEMINFORM, Issue 45 2004
    N. P. Bagrina
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Highly Substituted Furans from 2-Propynyl-1,3-dicarbonyls and Organic Halides or Triflates via the Oxypalladation-Reductive Elimination Domino Reaction.

    CHEMINFORM, Issue 43 2003
    Antonio Arcadi
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Indium-Mediated Domino Reaction of Nitroarenes with 2,3-Dihydrofuran in Water: An Efficient Synthesis of 1,2,3,4-Tetrahydroquinoline Derivatives.

    CHEMINFORM, Issue 31 2003
    Liang Chen
    Abstract For Abstract see ChemInform Abstract in Full Text. [source]

    Stereoselective Synthesis of Bicyclic Nitrocyclopropanes by a Radical,Anion Domino Reaction

    CHEMISTRY - A EUROPEAN JOURNAL, Issue 40 2009
    Akio Kamimura Prof.
    A novel one-step radical-ionic cyclopropanation was carried out to prepare aza- or oxabicyclo[3.1.0]hexane from ,-nitroamides or ,-nitroethers in a stereoselective manner (see scheme). The present procedure involves a higher-order domino process that includes one-electron oxidation, radical cyclization,intramolecular SN2 reaction. [source]

    Multicomponent Access to Functionalized Mesoionic Structures Based on TFAA Activation of Isocyanides: Novel Domino Reactions

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 5 2009
    María José Arévalo
    Abstract The reactions of azines (isoquinolines, pyridine) with TFAA and isocyanides in a new domino process yield mesoionic acid fluorides with an imidazo[1,2- a]azine core. This multicomponent reaction has a general character, tolerating a wide range of substitution patterns on each component, and displays an unprecedented arrangement of reaction pathways. The protocol allows the incorporation of a fourth synthetic input by the reaction of a suitable nucleophile (alcohols, thiols, amines) with the acid fluoride moiety.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]

    Synthesis of 1,3-Difunctionalized Cyclopentenes and 1,3,5-Trifunctionalized Cyclohexanes by Silicon-Induced Domino Reactions

    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 6 2003
    Frank Tries
    Abstract A novel domino process based on a 1,4-C,O shift of a silyl group (4 , 3) and a Michael-induced ring-closure reaction (3 , 2) is investigated. Specifically, attack of carbanions 5 on vinyloxiranes 6 usually occurs on the oxirane unit to give the desired silyl shift. When starting from vinyloxiranes 6a and 6b, however, the reaction stops at this stage to give silyl ethers 7. Sulfur (6c) or silicon activation (6d,f) of the C=C unit is required to yield cyclopentenes 1a,d. Analogously, carbanion 5a and allyloxiranes 15 give cyclization products 19,22, particularly if the ring-closure step is supported by silicon substitution. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003) [source]

    Alkynyl Group as Activating Group: Base-Catalyzed Diastereoselective Domino Reactions of Electron-Deficient Enynes

    ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009
    Wenbo Li
    Abstract This paper describes a base-catalyzed domino reaction of electron-deficient enynes with malonate-derived ,,,-unsaturated esters and ketones, which provides a rapid, stereoselective access to multi-functionalized cyclopentanes and inden-5(6,H)-ones in high yields. In this reaction, the alkynyl group of the enyne acts as an activating group rather than a reacting group. [source]

    ChemInform Abstract: Combinatorial Synthesis of Substituted Thieno[3,2-b]pyridines and Other Annulated Heterocycles via New SNS,Thorpe,Ziegler,Thorpe,Guareschi Domino Reactions.

    CHEMINFORM, Issue 24 2010
    Anatoliy M. Shestopalov
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Triethylamine-Catalyzed Domino Reactions of 1,3-Thiazolidinedione: A Facile Access to Functionalized Dihydrothiophenes.

    CHEMINFORM, Issue 8 2010
    Jing Sun
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Microwave-Assisted Domino Reactions: Function-Compatibility, Modulation, and Greening Efforts.

    CHEMINFORM, Issue 51 2008
    Andrei Corbu
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Pd(OAc)2 -Catalyzed Domino Reactions of 1,2-Dihaloarenes and 2-Haloaryl Arenesulfonates with Grignard Reagents: Efficient Synthesis of Substituted Fluorenes.

    CHEMINFORM, Issue 34 2008
    Cheng-Guo Dong
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    ChemInform Abstract: Exploring Modular Domino Reactions: Competing Processes Based on the Nature of the Angular Substituent.

    CHEMINFORM, Issue 14 2008
    Zobida Elkhayat
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

    Highly Diastereoselective Ionic/Radical Domino Reactions: Single Electron Transfer Induced Cyclization of Bis-sulfoxides.

    CHEMINFORM, Issue 47 2007
    Jean-Philippe Goddard
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    Thermally Induced Cyclobutenone Rearrangements and Domino Reactions.

    CHEMINFORM, Issue 16 2007
    David C. Harrowven
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    Asymmetric Synthesis of Highly Functionalized Tetrahydrothiophenes by Organocatalytic Domino Reactions.

    CHEMINFORM, Issue 12 2007
    Sven Brandau
    Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

    PdCl2 -Catalyzed Domino Reactions of 2-Alkynylbenzaldehydes with Indoles: Synthesis of Fluorescent 5H -Benzo[b]carbazol-6-yl Ketones

    CHEMISTRY - A EUROPEAN JOURNAL, Issue 16 2010
    Ri-Yuan Tang
    Synthetic methods: A new, selective Pd-catalyzed domino reaction of 2-alkynylbenzaldehydes with indoles has been developed for the synthesis of 5H -benzo[b]carbazol-6-yl ketones. The isobenzopyrylium complex is trapped by indole at room temperature to give 3-(1H -isochromen-1-yl)-1H -indoles, which can be transformed into 5H -benzo[b]carbazol-6-yl ketones by raising the temperature (see scheme). These ketones exhibit intense fluorescence and interact with metal ions to enhance the fluorescence intensity. [source]