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Direction Opposite (direction + opposite)
Selected AbstractsNovel negatively charged tentacle-type polymer coating for on-line preconcentration of proteins in CEELECTROPHORESIS, Issue 4 2009Liang Xu Abstract A novel negatively charged tentacle-type polymer-coated capillary column was fabricated and applied for on-line extraction and preconcentration of proteins. The polymer coating was prepared by glycidyl-methacrylate graft polymerization in a silanized capillary column and the following sulfonic acid group functionalization. It had high surface area and offered high phase ratio for protein adsorption. In addition, the polymer-coated capillary column provided more stable EOF than a bare uncoated capillary. These features of the polymer coating facilitated the extraction of proteins through electrostatic interactions. This was used to extract proteins. The extracted analytes were then desorbed and focused by EOF in the direction opposite to the sample injection flow for subsequent CE. With this procedure, over 1500-fold sensitivity enhancement was realized for myoglobin (MB) as compared with a normal capillary zone electrophoresis. By comparison of the peak areas of the enriched protein, it was found that the polymer-coated column could capture proteins about 30 times more than the uncoated column. In addition, the separation of a protein mixture containing 0.4,,g/mL of MB and 0.4,,g/mL of insulin was demonstrated by the on-line preconcentration and electrophoretic separation with the polymer-coated column. [source] Concurrent action observation modulates practice-induced motor memory formationEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 3 2008K. Stefan Abstract Motor practice is associated with the formation of elementary motor memories. Here we tested in human subjects the hypothesis that observation of a motor training associated with physical practice will modulate the encoding process of a motor memory relative to physical practice alone. Voluntary thumb motions were practiced (i) alone in a direction opposite to the baseline direction of transcranial magnetic stimulation (TMS)-evoked movements (physical practice, PP) and in combination with observation of synchronous movements that were either (ii) directionally congruent (same direction, PP + AOc) or (iii) non-congruent (opposite direction, PP + AOnc) to the practiced ones. We evaluated the following measures of motor memory formation: percentage of TMS-evoked thumb movements falling in the direction of practiced motions, acceleration of TMS-evoked movements along the principal movement axis and corticomuscular excitability of training muscles as indexed by motor-evoked potential amplitudes. Both PP and PP + AOc, but not PP + AOnc, significantly increased the percentage of TMS-evoked movements falling in the practiced direction, changed the compound acceleration vector into the trained direction and enhanced the motor-evoked potential amplitudes in the training agonist muscle. The percentage of TMS-evoked movements falling in the practiced direction increased significantly more after PP + AOc than after PP. Across all measures of motor memory formation, PP + AOc was most efficacious, followed by PP and PP + AOnc. Action observation modulates practice effects on formation of a motor memory. Strengthening of the process of motor memory encoding depends on the directional congruency of the observed model. [source] Knowledge Transfer and Collaboration in Distributed U.S.-Thai TeamsJOURNAL OF COMPUTER-MEDIATED COMMUNICATION, Issue 4 2005Saonee Sarker This article reports on a study that investigates factors influencing knowledge transfer in the context of cross-cultural distributed teams engaged in information systems development. The goal was to examine the validity of a four-factor framework of knowledge transfer (the "4 C Framework"), which proposes that capability, credibility, communication, and culture of the source significantly affects knowledge transfer. The framework is examined in the context of US-Thai distributed teams, as well as within the local subgroups. Results support the role of credibility and communication on knowledge transfer in the cross-cultural distributed teams, and within the local subgroups. Capability was not found to be related to knowledge transfer either in the distributed teams or within the local subgroups. Finally, culture of the source did affect knowledge transfer in the distributed teams, although in a direction opposite to that hypothesized. [source] ERP correlates of online monitoring of auditory feedback during vocalizationPSYCHOPHYSIOLOGY, Issue 6 2009Colin S. Hawco Abstract When speakers hear the fundamental frequency (F0) of their voice altered, they shift their F0 in the direction opposite the perturbation. The current study used ERPs to examine sensory processing of short feedback perturbations during an ongoing utterance. In one session, participants produced a vowel at an F0 of their own choosing. In another session, participants matched the F0 of a cue voice. An F0 perturbation of 0, 25, 50, 100, or 200 cents was introduced for 100 ms. A mismatch negativity (MMN) was observed. Differences between sessions were only found for 200-cent perturbations. Reduced compensation when speakers experienced the 200-cent perturbations suggests that this larger perturbation was perceived as externally generated. The presence of an MMN, and no earlier (N100) response suggests that the underlying sensory process used to identify and compensate for errors in mid-utterance may differ from feedback monitoring at utterance onset. [source] Normal Development of the Muscular Region of the Interventricular Septum.ANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 3 2009Summary In a first paper, we concluded that the muscular region of the interventricular septum is developed by the trabecular branches and showed evidence that the developing interventricular septum elongates in a direction opposite to that of atria. Nevertheless, to date the literature is lacking precise information on the importance of myocardial proliferation not only in this process but also in the morphogenesis of the ventricular cavities. The aim of this study was to determine the spatial and temporal distribution of high-intensity foci of cycling myocytes in the ventricular region of the heart of chicken embryos during cardiac septation. Histological studies, detection of the proliferating cell nuclear antigen by light and confocal microscopy and flow cytometric analysis were carried out. The results corroborate that the developing interventricular septum grows in a direction opposite to that of atria. A remoulding mechanism that results in fenestrated trabecular sheets and trabecular branching is discussed. Our findings allowed us to summarize the normal morphogenesis of the muscular region of the interventricular septum in a way that is different from that suggested by other researchers. [source] The relationship between attention deficit hyperactivity disorder, conduct disorder, and psychopathy in adolescent male and female detaineesBEHAVIORAL SCIENCES & THE LAW, Issue 4 2009Kathrin Sevecke M.D. Although ADHD and CD are apparent risk factors for adult psychopathy, there are three distinct perspectives regarding their relationships to psychopathy: (1) ADHD may contribute uniquely to the development of psychopathy or (2) its contribution may reflect its high comorbidity with CD. Alternatively, (3) the comorbid presence of ADHD and CD may confer unique risk for the development of psychopathy. Although prior adult studies have yielded conflicting findings, no prior studies of adolescents address this issue. We examined these three hypotheses and the possibility of sex differences using cross-sectional analyses in 90 male and 123 female incarcerated adolescents. Among males the influence of ADHD was largely attributable to the overlap between ADHD and CD, whereas among females ADHD contributed independently to psychopathy scores and to scores on several dimensions of psychopathy. In addition, among females, the ADHD,×,CD interaction was significant for the total score and the antisocial component of psychopathy and in a direction opposite to that predicted by the comorbid subtype hypothesis. These findings indicate that there may be sex-specific pathways to elevations in psychopathic traits and suggest that the comorbid subtype hypothesis is probably not correct for either boys or girls. Copyright © 2009 John Wiley & Sons, Ltd. [source] Strategic and Contextual Influences on Firm Growth: An Empirical Study of FranchisorsJOURNAL OF SMALL BUSINESS MANAGEMENT, Issue 2 2002Gary J. Castrogiovanni This study examined five-year growth patterns among a sample of 246 franchise networks in order to identify factors associated with network growth. Two strategic factors and two contextual factors were significantly related to growth. Among those four significant factors, however, two of the relationships were in directions opposite of those hypothesized. The most likely explanations of these findings, taken together, suggest that both strategy and context exert influences on growth, though strategic influences may be greater than contextual ones. [source] | |||||||||||||