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Different Standards (different + standards)
Selected AbstractsDoes the Emergency Exception from Informed Consent Process Protect Research Subjects?ACADEMIC EMERGENCY MEDICINE, Issue 11 2005Nicole M. Delorio MD Abstract Although subject protection is the cornerstone of medical ethics, when considered in the context of research using emergency exception from informed consent, its success is debatable. The participants of a breakout session at the 2005 Academic Emergency Medicine Consensus Conference discussed the issues surrounding subject protection and advanced the following recommendations. 1) There are no outcome measures that define "protection"; therefore, it is not currently known whether or not subjects are protected under the current rules. 2) Care must be taken to protect not only the individual from harm during research but also to protect society from unregulated research in other countries and an inability to appropriately advance medical knowledge. 3) Some surrogate markers/methods of protection whose efficacies are debatable include data safety monitoring board activity, the community consultation and public notification (CC/PN) process, and institutional review board approval. 4) Minimal-risk studies should be held to different standards of protection than those that involve more significant risk to the subject. 5) A handful of studies have been published regarding community consultation and notification, and the majority are case studies. Those that are specifically designed to discover the most successful methods are hindered by a lack of formal outcomes measures and tend to have negative results. 6) Follow-up data from the CC/PN process should be disclosed to the Food and Drug Administration and incorporated into study designs. 7) Focus groups and/or random-digit dialing have been suggested as promising methods for fulfilling the CC/PN requirements. 8) Studies need to be funded and performed that formally investigate the best means of CC/PN. 9) More funding for this research should be a priority in the emergency medicine and critical care communities. More data regarding terminated studies should be made available to the research community. 10) Quantifiable markers of success for CC/PN must be validated so that research may determine the most successful methods. 11) Data regarding subjects' and family members' experiences with exception from informed consent studies need to be obtained. [source] Interaction equations for multiaxial fatigue assessment of welded structuresFATIGUE & FRACTURE OF ENGINEERING MATERIALS AND STRUCTURES, Issue 11 2004M. BÄCKSTRÖM ABSTRACT Multiaxial fatigue data from 233 welded test specimens taken from eight different studies have been evaluated based on three published interaction equations for normal and shear stress. The interaction equations were obtained from SFS 2378, Eurocode 3 and International Institute of Welding (IIW) recommendations. Fatigue classes for normal and shear stress were obtained directly from the design guidance documents. Additionally, mean fatigue strengths were determined by regression analysis of bending only and torsion only data for different specimen types. In some cases, the S,N slopes assumed by the different standards were not appropriate for the test data. Specimens that showed significantly different cracking locations or cracking mode between bending and torsion were not easily correlated by the interaction equations. Interaction equations work best in cases where both the normal stress and the shear stress tend to produce crack initiation and growth in the same location and in the same direction. The use of a damage summation of 0.5 for non-proportional loading as recommended by IIW was consistent with experimental observations for tube-to-plate specimens. Other codes used a damage sum of unity. [source] ISO 14001 EMS standard registration decisions among Canadian organizationsAGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 4 2003Emmanuel K. Yiridoe This study characterized the costs and benefits associated with adopting ISO 14001 environmental management system (EMS) standard, based on a survey of ISO 14001-registered organizations in Canada. Decision makers are contemplating whether it is necessary to register to one or more of the ISO and other international standards and, if so, which ones. Furthermore, an organization that has registered separate departments to different standards and contemplates integrating such standards across the different units may be interested in attributes of particular units that will facilitate integration. Discriminant analysis was conducted to characterize the factors that distinguish between organizations that adopted ISO 14001 alone (single standard), versus those that registered to ISO 14001 along with other quality, health, and safety standards (i.e., multiple standards). The most important factor that motivated adoption to ISO 14001 was to establish a positive environmental profile, thereby promoting goodwill and integrity. Internal factors tended to dominate the motivations for adopting ISO 14001, supporting the hypothesis that external benefits may not be fully realized due to market and policy failure. Internal costs associated with registration depended on the size of the organization and ranged, on average, from CND$17,000 (for organizations with less than 100 employees), to CND$42,000 (for organizations with more than 500 employees). External costs depended more on the type (i.e., sector of the Canadian economy) than on size of the organization. The most important variable that distinguished between Canadian organizations that adopted ISO 14001 alone versus those that adopted ISO 14001 and other standards was whether the organization had an international orientation, that is, those with more than 50% of services or exports to other countries. [EconLit citations: L150, L200, Q290]. © 2003 Wiley Periodicals, Inc. Agribusiness 19: 439,457, 2003. [source] A collaborative study to establish the 7th International Standard for Factor VIII ConcentrateJOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 1 2005S. Raut Summary., A candidate concentrate, preparation N (99/678), was assayed and calibrated, as a potential replacement, against four established factor (F) VIII concentrate standards: the current WHO 6th International Standard (IS) (97/616), the previous 5th IS (88/640), the Mega 1 standard and Ph. Eur. BRP Batch 2 standard, in a collaborative study involving 38 laboratories. All laboratories were instructed to use the ISTH/SSC recommendations, including predilution of concentrates in FVIII-deficient plasma. Several laboratories performed more than one assay method and altogether there were 27 sets of assays with the one-stage method, 31 with the chromogenic method, and 18 with both methods. There was good agreement between laboratories using each of the two methods for comparison of preparation N against the four established standards, with overall potencies by one-stage and chromogenic methods differing only by less than 2%. However, there were significant differences in potencies relative to the different standards, ranging from 10.1 IU per ampoule against the Ph. Eur.BRP2 to 11.4 against the WHO 6th IS. Accelerated degradation studies showed that the proposed standard is very stable, with a predicted loss of activity per year of less than 0.001% at the recommended storage temperature of ,20 °C. Various options for potency of preparation N were considered by the participants and by members of the ISTH/SSC FVIII/FIX Subcommittee. In November 2003, preparation N (NIBSC 99/678) was proposed to and accepted by the Expert Committee on Biological Standardization of the World Health Organization to be the 7th International Standard for Factor VIII Concentrate with an assigned potency of 11.0 IU per ampoule. [source] Integrated wide,narrow band antenna for multiband applicationsMICROWAVE AND OPTICAL TECHNOLOGY LETTERS, Issue 2 2010E. Ebrahimi Abstract In this article, a novel integration concept is introduced for multiband antennas. An integrated wide,narrow band antenna is presented, which is composed of a shorted microstrip patch integrated to a coplanar waveguide fed ultrawideband monopole antenna. The patch is printed on the reverse side of the substrate using the monopole antenna as a ground plane. A prototype of the antenna is fabricated and verified. This antenna adds the possibility to operate in two of different standards or frequency bands at any given time. © 2009 Wiley Periodicals, Inc. Microwave Opt Technol Lett 52: 425,430, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.24926 [source] Use of models to assess the reduction in contamination of water bodies by agricultural pesticides through the implementation of policy instruments: a case study of the Voluntary Initiative in the UKPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 12 2006James Garratt Abstract Through normal agricultural use, pesticides may reach environmental water bodies via several routes of entry. Various policies and initiatives exist to reduce the effects of pesticides in the environment. One such initiative in place in the UK is the Voluntary Initiative (VI). The VI is a voluntary scheme put forward by the Crop Protection Association with other crop protection and farming organisations to reduce the environmental impacts of pesticides. Mathematical models of pesticide fate can usefully be applied to examine the impact of factors influencing the contamination of water bodies by pesticides. The work reported here used water quality models to examine how changes in farmer behaviour could potentially impact pesticide contamination of environmental water bodies. As far as possible, uncalibrated, standard regulatory models were used. Where suitable models were not available, simple models were defined for the purposes of the study and calibrated using literature data. Scenarios were developed to represent different standards of practice with respect to pesticide user behaviour. The development of these scenarios was guided by the Crop Protection Management Plan (CPMP) aspect of the VI. A framework for the use of modelling in the evaluation of the VI is proposed. The results of the modelling study suggest that, in several areas, widespread adoption of the measures proposed in the VI could lead to reductions in pesticide contamination of environmental water bodies. These areas include pesticide contamination from farmyards, spray drift and field runoff. In other areas (including pesticide leaching to groundwater and contamination of surface water from field drains) the benefits that may potentially be gained from the VI are less clear. A framework to evaluate the VI should take into consideration the following aspects: (1) groundwater is more at risk when there is a combination of leachable compounds, vulnerable soils, shallow groundwater and high product usage; (2) surface water contamination from drains is most likely when heavy rain falls soon after application, the soils are vulnerable and product usage is high; (3) surface water contamination from drift is most likely when the distance between the spray boom and water body is small and product usage is high; (4) surface water contamination from farmyards is dependent on the nature of the farmyard surface, the competence of the spray operator and the level of product usage. Any policy or initiative to reduce pesticide contamination should be measured against farmer behaviour in these areas. © Crown copyright 2006. Reproduced with the permission of Her Majesty's Stationery Office. Published by John Wiley & Sons, Ltd. [source] Use of high-performance liquid chromatography/electrospray ionization collision-induced dissociation mass spectrometry for structural identification of monohydroxylated progesteronesRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 23 2004Min-Jung Kang For the structural identification of monohydroxylated progesterones synthesized by microorganisms, a method was developed using a combination of high-performance liquid chromatography and electrospray ionization collision-induced dissociation mass spectrometry (HPLC/ESI-CIDMS). The retention times and MS/MS spectra of 11 different standards at 30,eV were collected and compared. The identification of D-ring-hydroxylated progesterones (15, -, 16, -, 17, - and 21-OH-P) using ESI-CIDMS was not possible. However, they were separated chromatographically using a 65:35 mixture of water and acetonitrile containing 0.5% acetic acid. The other hydroxylated progesterones (2, -, 6, -, 7, -, 9, -, 11, -, 11, -, and 19-OH-P) could be identified by comparison of eight fragments. The complete separation of 11 standards was achieved chromatographically. The developed assay was evaluated by the identification of monohydroxylated progesterones produced by CYP106A2 from Bacillus megaterium ATCC 13368. Copyright © 2004 John Wiley & Sons, Ltd. [source] The Role of Resource Access, Market Considerations, and the Nature of Innovation in Pursuit of Standards in the New Product Development ProcessTHE JOURNAL OF PRODUCT INNOVATION MANAGEMENT, Issue 5 2003Arvind Sahay Standards influence new product development (NPD) in high-technology markets. However, existing work on standards has focused exclusively on one aspect of standards,compatibility standards. This article has the following goals. First, we delineate the concept of customer interface standards as distinct from compatibility standards. This distinction is important from a product development and technology adoption perspective. Second, we propose and show that antecedent factors may motivate a firm differently about the emphasis that the firm should put on a type of standard (compatibility or customer interface) that it follows. For example, we propose that appropriability regime affects pursuit of customer interface standards and compatibility standards differently. Finally, we illustrate how resource access and the nature of the innovation also influence a firm's decision to pursue a standard type. Finally, we propose that pursuit of different standards (customer interface or compatibility) affects the NPD process in terms of (1) sourcing and dissemination of technology and (2) the customer utility for the product, which influences adoption. We collected perceptual data from a sample of marketing and technology managers in high-tech industries in the UK using both formative and reflective scales to measure the constructs. Analysis of the data using LISREL supports our contention that compatibility standards and customer interface standards are distinct constructs and that appropriability regime influences compatibility standards and customer interface standards differently. We also find that pursuit of compatibility standards helps a firm to create direct externalities pursuit of customer interface standards helps firms to develop indirect network externalities and technological advantage in the market. Our findings have the following implications. First, managers need to account explicitly for the difference between compatibility and customer interface standards, as resource allocation decisions during the NPD process will determine where a firm puts more focus. The choices made by the firm,as to whether it pursues compatibility standards or customer interface standards,will determine the type of advantage that it can gain in the market. Given a firm's situation at a point in time, a greater focus on one standard type rather than the other may be the right approach. Such choices will influence resource allocation in the product development process. [source] Sustainability report in small enterprises: case studies in Italian furniture companiesBUSINESS STRATEGY AND THE ENVIRONMENT, Issue 3 2009Francesca Borga Abstract The recent evolution of the economic and social context has led enterprises to consider and assess corporate environmental and social impacts integrated with the traditionally measured economic and operating performances. ,,From this point of view, the international debate on the advantages given by the firms' adoption of socially responsible behaviour has been developed; the increasing consciousness of the social character in enterprises' activities has enlarged the interest in communication. For this reason, several different standards have been developed in order to transmit, to the stakeholders, data, information and approaches about environmental, social and sustainability topics related to the firm's activities. In this dynamic context, the features of SMEs require specific guidelines, which address the contents of an SME-oriented sustainability report. ,,In this perspective the aim is to design guidelines able to meet with these SMEs' requirements; seven case studies, on Italian furniture small enterprises, complete the study. Copyright © 2006 John Wiley & Sons, Ltd and ERP Environment. [source] | ||||||||||||||||