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Different Reasons (different + reason)
Kinds of Different Reasons Selected AbstractsDoes treatment of varicocele improve male fertility?ANDROLOGIA, Issue 3 2002W. Krause Summary. Treatment of varicocele is suggested in infertile men if sperm parameter values are abnormal. The effectiveness of the treatment with respect to fertility remains to be clarified. A multicentre, prospective randomized study on varicocele treatment in infertile men to demonstrate the superiority of sclerotization of the varicocele in preventing persistence, was started in 1995 with the collaboration of 15 German andrological centres. The primary endpoint was the incidence of pregnancy 1 year after randomisation. The number of cases needed to achieve the goal of the study was calculated at 460. However, three years after starting the study, only 67 patients had been randomized. Different reasons contributed to the poor recruitment. There was no significant increase in pregnancy rate in the treated group, compared to the controls, the confidence interval being 20.8% to 15.7%. The authors would like to encourage further collaborative study groups to start another prospective, randomized study with the aim of avoiding the costs and risks of varicocele treatment when its success remains unclear. [source] Organization, Management and Delegation in the French Water IndustryANNALS OF PUBLIC AND COOPERATIVE ECONOMICS, Issue 4 2001Jihad C. Elnaboulsi The water industry is largely a natural monopoly. Water distribution and sewerage services are characterized by networks and its natural monopoly derives from the established local networks of drinking water and sewers: they are capital intensive with sunk costs and increasing returns to scale. In France, local communities have a local requirement of providing public services under optimum conditions in terms of techniques and cost-effectiveness, and subject to respect different kind of standards in terms of water quality and level of services. They are responsible for producing and distributing drinking water, and collecting and treating wastewater. Furthermore, the French water utilities are required to be financially self-sufficient. Rate-setting varies across regions and local territories due to a variety of organizational features of services and availability of water resources. The management of these local public services can be public or private: local governments have the right, by the constitution, to delegate water service management to private companies which operate under the oversight of local municipal authorities. Today, nearly 80 per cent of the French population receive private distributed water. Different reasons are responsible for the poor performance and low productivity of most French public water utilities: technical and operational, commercial and financial, human and institutional, and environmental. Thus, many water public utilities have looked for alternative ways to provide water and sanitation services more efficiently, to improve both operational and investment efficiency, and to attract private finance. The purpose of this paper is to present the French organizational system of providing drinking water services, and collecting and treating wastewater services: legal aspects, contracts of delegation, and competition. [source] The emergence of the chordate body plan: some puzzles and problemsACTA ZOOLOGICA, Issue 1 2010Thurston C. Lacalli Abstract Lacalli, T.C. 2010. The emergence of the chordate body plan: some puzzles and problems. ,Acta Zoologica (Stockholm) 91: 4,10 Rather than being sessile filter feeders, ancestral chordates are now thought to have evolved from more active benthic animals, possibly hemichordate-like, that took to swimming, to generate something resembling modern amphioxus. This general picture conceals a number of specific problems that underline how little we understand the transition in detail. I will address three. First, and closest to resolution is the issue of dorsoventral inversion, which has implications for understanding how an internalized brain evolved. This is because the mouth, dorsal after inversion, has first to be moved out of the way. Its migration down the left side of the head during amphioxus development may be a recapitulation of this event. Two other puzzles, both further from resolution are: (1) the significance, if any, of the neurenteric canal, which may be telling us something important about the true nature of deuterostomy, specifically whether hemichordates and echinoderms are deuterostomes for a different reason than chordates, and (2) whether the functional digestive tract of chordates is a secondary replacement of an earlier structure whose fate remains unexplained. Resolving these latter two issues will require a better understanding of molecular level events during development in protochordates and their immediate invertebrate relatives. [source] The Disparate Nature of Targeted Repurchases: Evidence from Long-Run PerformanceJOURNAL OF BUSINESS FINANCE & ACCOUNTING, Issue 1-2 2007Saeyoung Chang Abstract:, We examine the announcement stock returns and long-run performance of 352 targeted repurchases from 1979 to 1998. For those repurchases of blocks that are non-control related we find a positive announcement stock price response and positive long-run stock performance indicating that these repurchases are timed to occur when the company's shares are undervalued and that the market underreacts to this signal. In contrast, for those repurchases of blocks that are control related we find a negative announcement stock price response and insignificant long-run stock performance indicating that these repurchases occur for a different reason. We conclude that control related repurchases are utilized solely to dismiss potential takeover bids and are not timed when the stock is undervalued. [source] The Clerk, the Thief, His Life as a Baker: Ashton Embry and the Supreme Court Leak ScandalJOURNAL OF SUPREME COURT HISTORY, Issue 1 2002John B. Owens On December 16, 1919, Ashton Fox Embry, law clerk to Supreme Court Justice Joseph McKenna, abruptly resigned from the position he had held for almost nine years. His explanation? His fledgling bakery business required his undivided attention. Newspapers that morning hinted at a different reason: Embry resigned because he had conspired with at least three individuals to use inside knowledge of upcoming U.S. Supreme Court decisions to profit on Wall Street.2 A grand jury returned an indictment against Embry and his associates a few months later, and Embry's argument that he had committed no crime ultimately reached the Supreme Court, the very institution he was accused of betraying. Despite the sensational headlines and fierce legal battle arising from his indictment, the United States Attorney quietly dismissed Embry's case in 1929, almost ten years after the story had broken. Few Court scholars have ever heard of Embry, and the memory of Embry, much like the case against him, has disappeared with time.3 This article unravels the "Supreme Court Leak Case" by reconstructing what happened almost eighty years ago. [source] Addressing Association Entropy by Reconstructing Guanidinium Anchor Groups for Anion Binding: Design, Synthesis, and Host,Guest Binding Studies in Polar and Protic SolutionsCHEMISTRY - A EUROPEAN JOURNAL, Issue 20 2008Vinod Abstract The bicyclic hexahydropyrimidino[1,2a]pyrimidine cationic scaffold has a well-known capacity to bind a variety of oxoanions (phosphates, carboxylates, squarates, phosphinates). Based on this feature, the parent host was supplemented with sec -carboxamido substituents to generate compounds 1,3 in an effort to improve the anion-binding affinity and selectivity and to learn about the role and magnitude of entropic factors. Bicyclic guanidinium compounds were prepared by a convergent strategy via the corresponding tetraester 22 followed by catalytic amidation. Host,guest binding studies with isothermal titration calorimetry in acetonitrile probed the behavior of artificial hosts 1,3 in comparison with the tetraallylguanidinium compound 4 on binding p -nitrobenzoate, dihydrogenphosphate, and 2,2,-bisphenolcyclophosphate guests that showed enhanced affinities in the 105,106,M,1 range. Contrary to expectation, better binding emerges from more positive association entropies rather than from stronger enthalpic interactions (hydrogen bonding). In an NMR spectroscopy titration in DMSO, o -phthalate was sufficiently basic to abstract a proton from the guanidinium function, as confirmed by an X-ray crystal structure of the product. The novel carboxamide-appended anchor groups also bind carboxylates and phosphates, but not hydrogen sulfate in methanol with affinities in excess of 104,M,1. The energetic signature of the complexation in methanol is inverted with respect to acetonitrile solvent and shows a pattern of general ion pairing with strong positive entropies overcompensating endothermic binding enthalpies. This study provides an example of the fact that bona fide decoration of a parent guanidinium anchor function with an additional binding functionality may provide the desired enhancement of the host,guest affinity, yet for a different reason than that implemented by design as guided by standard molecular modeling. [source] The notion of ,phonology' in dyslexia research: cognitivism,and beyondDYSLEXIA, Issue 3 2007Per Henning Uppstad Abstract Phonology has been a central concept in the scientific study of dyslexia over the past decades. Despite its central position, however, it is a concept with no precise definition or status. The present article investigates the notion of ,phonology' in the tradition of cognitive psychology. An attempt is made to characterize the basic assumptions of the phonological approach to dyslexia and to evaluate these assumptions on the basis of commonly accepted standards of empirical science. First, the core assumptions of phonological awareness are outlined and discussed. Second, the position of Paula Tallal is presented and discussed in order to shed light on an attempt to stretch the cognitive-psychological notion of ,phonology' towards auditory and perceptual aspects. Both the core assumptions and Tallal's position are rejected as unfortunate, albeit for different reasons. Third, the outcome of this discussion is a search for what is referred to as a ,vulnerable theory' within this field. The present article claims that phonological descriptions must be based on observable linguistic behaviour, so that hypotheses can be falsified by data. Consequently, definitions of ,dyslexia' must be based on symptoms; causal aspects should not be included. In fact, we claim that causal aspects, such as ,phonological deficit', both exclude other causal hypotheses and lead to circular reasoning. If we are to use terms such as ,phonology' and ,phoneme' in dyslexia research, we must have more precise operationalizations of them. Copyright © 2007 John Wiley & Sons, Ltd. [source] A single question for the rapid screening of restless legs syndrome in the neurological clinical practiceEUROPEAN JOURNAL OF NEUROLOGY, Issue 9 2007R. Ferri The purposes of this study were to validate the use of a single standard question for the rapid screening of restless legs syndrome (RLS) and to analyze the eventual effects of the presence of RLS on self-assessed daytime sleepiness, global clinical severity and cognitive functioning. We evaluated a group of 521 consecutive patients who accessed our neurology clinic for different reasons. Beside the answer to the single question and age, sex, and clinical diagnosis, the following items were collected from all patients and normal controls: the four criteria for RLS, the Epworth Sleepiness Scale (ESS), the Clinical Global Impression of Severity (CGI-S), and the Mini-Mental State evaluation. RLS was found in 112 patients (70 idiopathic). The single question had 100% sensitivity and 96.8% specificity for the diagnosis of RLS. ESS and CGI-S were significantly higher in both RLS patient groups than in normal controls. RLS severity was significantly higher in idiopathic than in associated/symptomatic RLS patients. RLS can be screened with high sensitivity and good reliability in large patient groups by means of the single question; however, the final diagnosis should always be confirmed by the diagnostic features of RLS and accompanied by a careful search for comorbid conditions. [source] A New Carrier for Selective Removal of Heavy Metal Ions from Aqueous Solutions through Bulk Liquid MembranesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 18 2004Nicoletta Spreti Abstract The carrier-mediated transport of heavy metal ions through bulk liquid membranes has been examined: toxic Hg2+, Cd2+ and Pb2+ ions were studied, along with Cu2+ ions for comparative purposes. The ability of a new carrier, 2,2,-bis(p -octyloxybenzyl)diethylenetriamine (bis- pODET), to complex and transport all the selected metal ions is reported. Differing affinities of the carrier for the different metal ions and the different experimental conditions required for their release into the receiving phase allowed the selective separation of equimolar binary mixtures. For Hg2+/Cd2+ and Hg2+/Pb2+ mixtures, two different separation methods were performed, while the inefficacy of the separation of Cd2+/Pb2+ and Hg2+/Cu2+ mixtures was for two different reasons: (i) the carrier is able to extract the metal ions with similar levels of ability, and (ii) the carrier metal ion complexes require the same acidity of the receiving phase to release the metal ions. The capability of the carrier to transport Hg2+ efficiently in consecutive cycles is also reported: over 90% of the metal ions were transferred into the receiving phase for three consecutive processes. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004) [source] Beyond Multilingualism: On Different Approaches to the Handling of Diverging Language Versions of a Community LawEUROPEAN LAW JOURNAL, Issue 1 2010Theodor Schilling This article deals with a problem created by the EU's multilingualism, the fallibility of translators and the ruses of politicians: for different reasons, it is quite common that equally authentic language versions of a Community law have different meanings if taken on their own. While the ECJ's uniform interpretation approach to this problem, which must be seen as required under the non-discrimination principle, has permitted equitable results in those cases decided by the ECJ, it would not be adequate for the simplest type of case, ie that a citizen has every reason to trust her own language version of a law. In such a case, her legitimate expectations in the equal authenticity of that version requires protection. De lege lata the article therefore proposes, in the interest of generally equitable solutions, a balancing, in the individual case, of the protection of legitimate expectations and the non-discrimination principle. De lege ferenda it proposes a more radical solution, ie that there be only one authentic version of every Community law. [source] Massive use of chemotherapy influences life traits of parasitic nematodes in domestic ruminantsFUNCTIONAL ECOLOGY, Issue 5 2001V. Leignel Summary 1,The size of nematodes is an operational indicator of fecundity. The variation in size due to chemotherapy was studied with a benzimidazole anthelmintic in susceptible and resistant nematodes. Teladorsagia circumcincta circumcincta (Stadelmann 1894), a nematode endoparasite of sheep and goats, was investigated as many components of its fitness are already known. 2,Susceptible worms submitted to increasing selective pressure by anthelmintics increased in size (by 6,10%); it was hypothesized that this was partly under the control of sheep, as treated lambs may mount and maintain a better response when infected (premunition). 3,The resistant worms, whatever the anthelmintic pressure, were always 3% larger than susceptible ones. 4,Thus, size may increase in susceptible worms and resistant worms for very different reasons. If resistance does not emerge, massive chemotherapy should lead to larger nematodes, and hence to more fertile worms. [source] An exploratory study of operational reasons to budgetACCOUNTING & FINANCE, Issue 4 2009Prabhu Sivabalan M00 Abstract Budgets are used widely but criticized, mainly for performance evaluation reasons. We find that organizations regard budgets as more important for planning and control than evaluation, thus proposing a rationale for their continued use irrespective of evaluation-based criticisms. This finding is also important, because most extant budget research focuses on evaluation, suggesting a potential disconnect between budget research and practice. We also find that rolling forecasts are used in tandem with the annual budget in most organizations, and for the same reasons. This was unexpected, as coexistence suggests their adoption for different reasons. [source] Pediatrics Access Problems in hemodialysis with a permanent central venous catheterHEMODIALYSIS INTERNATIONAL, Issue 1 2005J. Muscheites Hemodialysis is a common treatment of chronic renal failure, also in childhood. Due to the high standard of technique there are only few contraindications for this treatment at present. Limitations are given by the vessel access. But in the last years, hemodialysis has been made practicable by the permanent central venous catheter, however, with more problems. As an example for potential complications in the treatment with the permanent catheter we present an unusual case report about a twenty-one- year-old girl suffering from chronic renal failure due to reflux nephropathy, Prader-Willi- syndrome, myelonatrophia of undetermined origin with spastic diplegia of the legs, and increasing sphincter ani dysfunction. We started the renal replacement therapy when the girl was 15 years old. It was not possible to create an AV fistula due to very small vessels. Two Gore-Tex ® implants were clotted in absence of thrombophilia. Afterwards, the hemodialysis was performed by a permanent central venous catheter. The catheter had to be changed 15 times. The reasons for changing the catheter were problems of flow during hemodialysis due to clotting, dislocations, spontaneous removing of the catheter by herself, and infections. Altogether a sepsis occurred four times. The first transplantation failed due to a rupture of the transplanted kidney. A second transplantation was not possible because of the high BMI. Intermittently, the girl was treated with peritoneal dialysis (PD) in the hospital, because the PD couldn't be done at home due to different reasons. Only on weekends could the girl go home. The PD had to be finished after 6 months due to a severe psychotic syndrome. The girl died at age 21, caused by a sepsis following the 15th change of the catheter. A huge problem of frequent catheter changing is the limited availability of vessel accesses , the limits of treatment by hemodialysis. [source] The Christian Religion in Modern European and World History: A Review of The Cambridge History of Christianity, 1815,2000HISTORY COMPASS (ELECTRONIC), Issue 6 2008David Lindenfeld Volumes 8 and 9 of the Cambridge History, representing the work of 72 scholars, reflect two major recent historiographical trends: 1) the increased attention paid to religion in modern European history, and 2) the increasing importance of Christianity in as a topic in world history. While these volumes serve to summarize the work already done in the first field, with articles on a wide variety of European countries, they should significantly move the second field forward by bringing together the work of specialists on many different parts of the world in a single place. Volume 8 summarizes scholarship on the Western religious revivals of the nineteenth century, both Catholic and Protestant. By integrating religion and politics, it also presents a more complex picture of the formation of European national identities than Benedict Anderson's Imagined Communities suggests. One third of the volume is devoted to the spread of Christianity to the non-Western world. In Volume 9, the European and world history perspectives are more evenly interspersed. Major themes include the papacy, ecumenism, colonialism, Pentecostalism, and the independent churches of Africa and Asia. The 1960s emerge as a turning point, if for different reasons in different parts of the world. This was the decisive period of secularization in Europe, and the final section documents the social and cultural impact of that shift, particularly on the arts. Although there are inevitable gaps in coverage, these volumes will serve as an invaluable research tool for years to come. [source] Scan profiles for neutron spectrometers.JOURNAL OF APPLIED CRYSTALLOGRAPHY, Issue 5 2003The recent development of neutron collimators with rectangular transmission profiles (intensity versus angular divergence) extends hope of improved count rates on neutron scattering instruments. It is usually assumed that a more effective use of beam angular spread in these devices should increase count rates by about a factor of two. However, real beams have both angular and wavevector spread and both these spreads are governed by the allowed collimation. In this extended view, the gains from ideal rectangular-profile elements (angle filters) are shown to be much larger (about a factor of four). The mirror reflections used to achieve the rectangular profiles in real devices complicate the resolution effects. Specifically, the reflections disturb the wavevector,angular divergence correlation in the beams, leading to unusual peak shapes characterized by triple peaks on powder diffractometers. Thus, these reflecting collimators are likely to be universally useful only before the monochromator and immediately preceding the detector, where wavevector,angle correlations have no effect. This reduces the potential gains to a factor of two or so. Note that the gains are as previously expected but for quite different reasons than imagined. This remains a very significant gain in a field where most work is intensity-limited. [source] Reasons for therapy termination in a university psychology clinicJOURNAL OF CLINICAL PSYCHOLOGY, Issue 9 2002Kimberly Renk This study examined the reasons for therapy termination documented by graduate student therapists. The closed case files of individual adult clients who had terminated their therapy experience at a university-based psychology clinic were reviewed. Results indicated that the most frequent reasons for termination documented by graduate student therapists were that clients stopped attending therapy sessions without providing their therapists with notice or reason and that clients reached a satisfactory termination point in their therapy experience. A substantial number of clients terminated therapy because of difficulties unrelated to therapy, seeking services elsewhere, or dissatisfaction with therapy services. Level of depressive symptomatology and the number of sessions attended differed across clients who had different reasons for termination. By addressing such client concerns early in the therapy experience, premature termination may be prevented. © 2002 Wiley Periodicals, Inc. J Clin Psychol 58: 1173,1181, 2002. [source] Structural change and market power in the U.S. food manufacturing sectorAGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 2 2009Kyle W. Stiegert This study develops an intertemporally linked market model to explore the relationships between price-cost margins, market concentration, and advertising outlay. The study used data from 48 four-digit SIC (standardized industrial classification) codes for the Food and Tobacco Processing Industries during the 1970s, 1980s, and 1990s. The authors' findings provide evidence that both high and low levels of performance provide signals to industries to consolidate, but for obvious and different reasons. Further, increased consolidation leads to increased entry barriers (advertising) and higher profits to the industry. Our findings are supportive of both Chicago and Traditionalist Schools of thought about antitrust enforcement: Neither emerges in a dominant position. Endogeneity issues and findings within the intertemporal structure cast considerable doubt about overly simplistic structure,performance paradigms of firm behavior. [JEL Code: L11, L40, L66]. © 2009 Wiley Periodicals, Inc. [source] Maximum likelihood estimation of bivariate logistic models for incomplete responses with indicators of ignorable and non-ignorable missingnessJOURNAL OF THE ROYAL STATISTICAL SOCIETY: SERIES C (APPLIED STATISTICS), Issue 3 2002Nicholas J. Horton Summary. Missing observations are a common problem that complicate the analysis of clustered data. In the Connecticut child surveys of childhood psychopathology, it was possible to identify reasons why outcomes were not observed. Of note, some of these causes of missingness may be assumed to be ignorable, whereas others may be non-ignorable. We consider logistic regression models for incomplete bivariate binary outcomes and propose mixture models that permit estimation assuming that there are two distinct types of missingness mechanisms: one that is ignorable; the other non-ignorable. A feature of the mixture modelling approach is that additional analyses to assess the sensitivity to assumptions about the missingness are relatively straightforward to incorporate. The methods were developed for analysing data from the Connecticut child surveys, where there are missing informant reports of child psychopathology and different reasons for missingness can be distinguished. [source] Up and Down with the Agrarian Question: Issue Attention and Land Reform in Contemporary BrazilPOLITICS & POLICY, Issue 4 2008Gabriel Ondetti The two most recent Brazilian presidents have both surprised observers with their land reform programs but for very different reasons. Despite presiding over a center-right government with strong ties to large landowners and a state-shrinking economic program, Fernando Henrique Cardoso implemented easily the largest rural land redistribution in Brazilian history. As the leader of a leftist party and a historic champion of radical land reform, Luiz Inácio Lula da Silva seemed to have sterling pro-land reform credentials. Yet Lula's program has, by some key measures, fallen well short of Cardoso's. This article attempts to explain these two anomalous outcomes. Drawing on Downs' concept of the "issue-attention cycle," it argues that the trajectory of land reform under Cardoso and Lula largely reflects the impact of a variable rarely cited in analyses of Brazilian politics: public issue saliency. This argument holds implications for both the future of land reform in Brazil and our broader understanding of the Brazilian political system. [source] Uncertain Aims and Tacit Negotiation: Birth Control Practices in Britain, 1925,50POPULATION AND DEVELOPMENT REVIEW, Issue 2 2000Kate Fisher Evidence from oral history interviews is used to suggest the need to reevaluate our understanding of the dynamics of fertility decisions and behavior in the first half of the twentieth century. Those interviewed stressed their vague and haphazard approach to contraceptive use, in sharp contrast to the dominant depiction in studies of fertility decline that emphasize the degree to which individuals made deliberate and calculated choices about family size based on an assessment of the costs and benefits of childrearing. Details of individual contraceptive strategies elucidate the complexities of birth control behavior: couples, lacking explicit aims for family limitation, adopted diverse methods of birth control, using them for different reasons, at different times, with varying degrees of determination and confidence and frequently with very little direct discussion or planning. Explicit articulation of aims was not a necessary prerequisite of the spread of birth control; accepted gender roles meant that responsibilities and obligations emerged gradually and tacitly. As a result, nevertheless, low fertility was effectively achieved. [source] State Saving Behavior: Effects of Two Fiscal and Budgetary InstitutionsPUBLIC BUDGETING AND FINANCE, Issue 3 2008YILIN HOU This paper explores how state saving behavior is affected by two fiscal/budgetary institutions,budget stabilization funds (BSF) and balanced budget requirements (BBR). While adopted for different reasons, BSF and BBR could have significant effects on state savings behavior depending on their design features. We empirically examine the effects of BSF and BBR using a panel data set that covers three business cycles, controlling for budgetary institutions, state economy, social services, politics, and business cycles. The paper finds that adopting BSF and BBR can raise savings by 2 and 3 percentage points, respectively; however, the effects depend crucially on the devices' design. [source] Not so fast: Speed effects on forelimb kinematics in cercopithecine monkeys and implications for digitigrade postures in primatesAMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, Issue 1 2009Biren A. Patel Abstract Terrestrial mammals are characterized by their digitigrade limb postures, which are proposed to increase effective limb length (ELL) to achieve preferred or higher locomotor speeds more efficiently. Accordingly, digitigrade postures are associated with cursorial locomotion. Unlike most medium- to large-sized terrestrial mammals, terrestrial cercopithecine monkeys lack most cursorial adaptations, but still adopt digitigrade hand postures. This study investigates when and why terrestrial cercopithecine monkeys adopt digitigrade hand postures during quadrupedal locomotion. Three cercopithecine species (Papio anubis, Macaca mulatta, Erythrocebus patas) were videotaped moving unrestrained along a horizontal runway at a range of speeds (0.4,3.4 m/s). Three-dimensional forelimb kinematic data were recorded during forelimb support. Hand posture was measured as the angle between the metacarpal segments and the ground (MGA). As predicted, a larger MGA was correlated with a longer ELL. At slower speeds, subjects used digitigrade postures (larger MGA), however, contrary to expectations, all subjects used more palmigrade hand postures (smaller MGA) at faster speeds. Digitigrade postures at slower speeds may lower cost of transport by increasing ELL and step lengths. At higher speeds, palmigrade postures may be better suited to spread out high ground reaction forces across a larger portion of the hand thereby potentially decreasing stresses in hand bones. It is concluded that a digitigrade forelimb posture in primates is not an adaptation for high speed locomotion. Accordingly, digitigrady may have evolved for different reasons in primates compared to other mammalian lineages. Am J Phys Anthropol 2009. © 2009 Wiley-Liss, Inc. [source] The influence of gastroesophageal reflux in the lung: A case,control studyRESPIROLOGY, Issue 5 2010Kornelija MISE ABSTRACT Background and objective: Many researchers have investigated the pH of exhaled breath condensate but direct measurement of pH in the lung has not been performed in vivo in humans. We hypothesized that the pH measured directly in the lung would differ between healthy subjects and patients with gastroesophageal reflux disease (GERD). We also wished to determine whether an acidic environment in the lung influences pulmonary function and DLCO, and whether microaspiration of gastric contents directly influences non-specific inflammation in the lung. Methods: The patients were otherwise healthy individuals who had been newly diagnosed with GERD. The control subjects were mostly volunteers who underwent bronchoscopy for different reasons. For all subjects (n = 63) a medical history was taken, and physical examination, oesophagogastroduodenoscopy, fibre-optic bronchoscopy and pulmonary function testing were performed. Results: In patients with GERD the average pH in the lung was 5.13 ± 0.43; this was significantly lower than the pH in the lung of controls 6.08 ± 0.39 (P = 0.001). Patients with GERD had lower FEV1% (P = 0.035), PEF (P = 0.001), FEF50% (P = 0.002) and FEF25% (P = 0.003), while the differences in FVC% and FEF75% were not significant. DLCO (P = 0.003), as well as transfer coefficient of the lung (P = 0.001), was lower in patients with GERD. LDH levels in bronchoalveolar aspirate were higher in the patients with GERD (P = 0.001). Conclusions: This study found evidence of cell and tissue injury in the lung, a lowering of pH and higher bronchoalveolar aspirate LDH levels in patients with GERD compared with healthy subjects. These findings suggest that pulmonary function, and especially DLCO, should be evaluated in patients presenting with GERD. [source] Identifying Compact Symmetric Objects from the VLBA Imaging and Polarization SurveyASTRONOMISCHE NACHRICHTEN, Issue 2-3 2009S.E. Tremblay Abstract Compact Symmetric Objects (CSOs) are small (less than 1 kpc) radio sources which have symmetric double lobes or jets. The dominant theory for the small size of these objects is that they are young radio sources which could grow into larger radio galaxies, but the currently small population of known CSOs makes it difficult to definitively determine whether or not this is the case. While a greater number of Gigahertz peaked sources can be identified by sifting through spectral surveys, this yields none of the dynamics of the sources, and also brings Quasars into the sample, which although interesting are peaked around 1 Gigahertz for very different reasons. We have used the 5 GHz VLBA Imaging and Polarization Survey (VIPS) to identify 103 CSO candidates morphologically, and are following up on these sources with multifrequency VLBA observations to confirm CSO identifications and to study their dynamics. The identification of candidates from within the survey will be discussed, as well as preliminary results from the follow-up observations (© 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Schutz und Instandsetzung von Betonbauteilen mit genormten Produkten nach EN 1504BETON- UND STAHLBETONBAU, Issue 10 2006M. Raupach Prof. Dr.-Ing. Die Europäische Normenreihe EN 1504 für Schutz und Instandsetzung von Betonbauteilen steht unmittelbar vor ihrer Fertigstellung. Sie besteht aus 10 Hauptnormen und 62 zugehörigen Europäischen Prüfnormen. Die Hauptnormen EN 1504-2 bis 7 regeln die Produktgruppen Oberflächenschutzsysteme, Mörtel, Klebstoffe für Verstärkungen, Riß- und Hohlraumfüllstoffe, Ankermörtel sowie die Stahlbeschichtungen. Die Prinzipien für den Gebrauch der Produkte sowie die Anwendung der Produkte auf der Baustelle mit zugehöriger Qualitätssicherung sind in den Teilen 9 und 10 enthalten. Ferner ist die Qualitätssicherung der Produkte in Teil 8 geregelt. Somit liegt in Kürze ein umfassendes Normenwerk für Schutz und Instandsetzung von Betonbauteilen vor. Derzeit wird beraten, wie dieses Normenwerk in Deutschland eingeführt wird. Aus verschiedenen Gründen wurde beschlossen, daß die Teile für Planung und Anwendung in Deutschland nicht eingeführt werden, weil mit den bestehenden Richtlinien des DAfStb "Schutz und Instandsetzung von Betonbauwerken" sowie der ZTV-ING langjährig bewehrte Regelwerke vorliegen. Um die Europäisch zukünftig mit CE-Zeichen markierten Produkte für Schutz und Instandsetzung von Betonbauwerken verwenden zu können, wurden für den Oberflächenschutz, die Mörtel, Rißfüllstoffe und die Stahlbeschichtungen inzwischen entsprechende Restnormen (DIN V 18026 bis 18028) erarbeitet, während die Kleber und Ankermörtel wie bisher in Zulassungen geregelt werden. In diesem Beitrag wird beschrieben wie zukünftig in Deutschland Schutz und Instandsetzung von Betonbauteilen mit genormten Produkten nach EN 1504 erfolgen soll. Repair and protection of concrete structures using products according to the standard EN 1504 The European series of standards EN 1504 for protection and repair of concrete structures is actually more or less finished. It consists of 10 main standards and 62 European test standards. The main standards EN 1504-2 to 7 refer to the product classes surface protection systems, mortars, adhesives for strengthening, materials for filling of cracks and voids, anchoring products as well as protection materials for the steel surface. The principles for the use of the products and systems as well as the application of the products on site including quality assurance are regulated in parts 9 and 10. Furthermore the quality assurance for the products is described in part 8. In this way within the next months an extensive set of standards for protection and repair of concrete structures is available. Actually it is discussed, how this set of standards will be introduced in Germany. Due to different reasons it has been decided, that the parts for design and application will not be introduced in Germany, because the existing standards of the DAfStb "Protection and repair of concrete structures" as well as the ZTV-ING have been used successfully for several years. To be able to use the European CE-marked products for protection and repair of concrete structures in future in Germany, for surface protection, mortars, materials for filling of cracks and voids as well as steel coatings in the meantime additional standards (DIN V 18026 to 18028) have been worked out, while the adhesives and anchoring products will be handled via approvals as before. This paper describes, how protection and repair of concrete structures will be carried out in Germany with CE-marked products according to EN 1504. [source] Climatic variability and the evolution of insect freeze toleranceBIOLOGICAL REVIEWS, Issue 2 2003BRENT J. SINCLAIR ABSTRACT Insects may survive subzero temperatures by two general strategies: Freeze-tolerant insects withstand the formation of internal ice, while freeze-avoiding insects die upon freezing. While it is widely recognized that these represent alternative strategies to survive low temperatures, and mechanistic understanding of the physical and molecular process of cold tolerance are becoming well elucidated, the reasons why one strategy or the other is adopted remain unclear. Freeze avoidance is clearly basal within the arthropod lineages, and it seems that freeze tolerance has evolved convergently at least six times among the insects (in the Blattaria, Orthoptera, Coleoptera, Hymenoptera, Diptera and Lepidoptera). Of the pterygote insect species whose cold-tolerance strategy has been reported in the literature, 29% (69 of 241 species studied) of those in the Northern Hemisphere, whereas 85%(11 of 13 species) in the Southern Hemisphere exhibit freeze tolerance. A randomization test indicates that this predominance of freeze tolerance in the Southern Hemisphere is too great to be due to chance, and there is no evidence of a recent publication bias in favour of new reports of freeze-tolerant species. We conclude from this that the specific nature of cold insect habitats in the Southern Hemisphere, which are characterized by oceanic influence and climate variability must lead to strong selection in favour of freeze tolerance in this hemisphere. We envisage two main scenarios where it would prove advantageous for insects to be freeze tolerant. In the first, characteristic of cold continental habitats of the Northern Hemisphere, freeze tolerance allows insects to survive very low temperatures for long periods of time, and to avoid desiccation. These responses tend to be strongly seasonal, and insects in these habitats are only freeze tolerant for the overwintering period. By contrast, in mild and unpredictable environments, characteristic of habitats influenced by the Southern Ocean, freeze tolerance allows insects which habitually have ice nucleators in their guts to survive summer cold snaps, and to take advantage of mild winter periods without the need for extensive seasonal cold hardening. Thus, we conclude that the climates of the two hemispheres have led to the parallel evolution of freeze tolerance for very different reasons, and that this hemispheric difference is symptomatic of many wide-scale disparities in Northern and Southern ecological processes. [source] Low rates of colorectal, cervical, and breast cancer screening in Asian Americans compared with non-Hispanic whitesCANCER, Issue 1 2006Cultural influences or access to care? Abstract BACKGROUND Asian Americans have lower cancer screening rates compared with non-Hispanic whites (NHWs). Little is known about mechanisms that underlie disparities in cancer screening. The objectives of the current study were 1) to determine the relation between nativity, years in the United States, language, and cancer screening in NHWs and Asian Americans, independent of access to care and 2) to determine whether Asians reported different reasons than NHWs for not obtaining cancer screening. METHODS This population-based study included 36,660 NHWs, 1298 Chinese, 944 Filipinos, 803 Koreans, 857 Vietnamese, and 1036 Other Asians from the 2001 California Health Interview Survey. The main study outcomes were 1) self-reported colorectal, cervical, and breast cancer screening and 2) reasons for not obtaining cancer screening. RESULTS After adjusting for access to care, several Asian subgroups still had significantly lower rates of all types of cancer screening compared with NHWs. Adjusting for nativity, years in the United States, and English language attenuated the relation between Asian ethnicity and lower rates of colorectal and breast cancer screening. When they were asked what the most important reason was for not having each screening test, foreign-born Asians were significantly more likely than United States-born NHWs to report that they "didn't have problems/symptoms" (P<.01). CONCLUSIONS Nativity, years in the United States, and English language may be markers of cultural differences that are mediating cancer screening disparities. Foreign-born Asians may believe that cancer screening is in response to symptoms rather than tests that are used prior to the development of symptoms. Health education messages must consider how to communicate effectively that "cancer screening is valuable, because it finds cancer before it is advanced enough to cause symptoms." Cancer 2006. © 2006 American Cancer Society. [source] Experience with adalimumab for the treatment of non-infectious uveitisACTA OPHTHALMOLOGICA, Issue 2009B DOBNER Purpose Objective: The aim of this study has been to assess the efficacy of adalimumab (ADA) in patients with uveitis in 3 centers. Methods In a retrospective study we identified patients from all instituitions´databases, who were treated with ADA in an average period of 20.16 months (range 1.3-45 months). The 5 criteria that the efficacy of ADA had been judged on are: reduction of macular edema by OCT, visual acuity, anterior chamber cells, reduction of flares and a reduction of prednisone dose during the treatment. At least one of the criteria had to be improved and none of the others worsened to declare treatment as effective. Results Of the 61 patients who were treated with ADA, 38 were treated for uveitis and systemic disease, 3 primarily for active systemic disease and 20 primarily for active uveitis. 15 patients had been treated before with etanercept and 11 with infliximab, with insufficient response. We saw an improvement in 49 out of these 61 patients (80,3%) in 1 or more criteria and worsening in none, 5 patients did not meet improvement criteria and were given additional or alternative treatment, three of them mainly due to activity of systemic disease. 14 out of 49 (28,6%)Patients showed an Improvement in every criteria, the other patients showed increasing in at least one criteria, the other criterias remained stable. At the last follow-up there were 50 (81,9%) patients still on ADA treatment. 11 patients stopped ADA treatment for different reasons (inefficacy, active systemic disease, pregnancy etc.). Conclusion In this retrospective study we judged that the treatment with ADA in patients with uveitis with or without systemic disease was effective in 80,3%. Clinical trials are warrented Commercial interest [source] The reasons why young children are placed for adoption: findings from a recently placed sample and a discussion of implications for subsequent identity developmentCHILD & FAMILY SOCIAL WORK, Issue 4 2000E. Neil It is widely accepted that the processing of identity issues can be problematic for some adopted children. Needing to know why placement for adoption was necessary is often central to adopted people's identity concerns. Adoption practices have altered and children are now placed for adoption for different reasons and from different backgrounds than were children in the past. This study aims to present an up to date picture of the reasons why children are placed for adoption. Using information from questionnaires completed by social workers, the circumstances of a sample of 168 young (mean age at placement = 18 months), recently adopted children are examined. Children fall into three groups according to the reason for their adoption: relinquished infants (14%), those whose parents had requested adoption in complex circumstances (24%), and those children required to be adopted by social services and the courts (62%). Child and birthparent characteristics and openness arrangements are examined and are found to differ significantly between the three groups, indicating that children will have different types of information to appraise and differing capacities to make sense of their personal histories. Because of the multiplicity of difficulties in children's backgrounds, it is concluded that resolving identity issues is likely to be challenging for many children, and professionals will need to take this into account when working with adopters and birth relatives. [source] | ||||||||||||||||||||||||||||