Diagnosis

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of Diagnosis

  • accurate diagnosis
  • accurate preoperative diagnosis
  • additional diagnosis
  • adhd diagnosis
  • admission diagnosis
  • aid diagnosis
  • alcohol-related diagnosis
  • allergy diagnosis
  • alternative diagnosis
  • antemortem diagnosis
  • antenatal diagnosis
  • anxiety diagnosis
  • appropriate diagnosis
  • asd diagnosis
  • asthma diagnosis
  • benign diagnosis
  • biopsy diagnosis
  • breast cancer diagnosis
  • cancer diagnosis
  • cardiac diagnosis
  • caries diagnosis
  • cd diagnosis
  • certain diagnosis
  • cf diagnosis
  • child diagnosis
  • clinical diagnosis
  • clinician diagnosis
  • common diagnosis
  • comorbid diagnosis
  • computer-aided diagnosis
  • conclusive diagnosis
  • concurrent diagnosis
  • confirmed diagnosis
  • consensus diagnosis
  • correct diagnosis
  • ct diagnosis
  • current diagnosis
  • cytologic diagnosis
  • cytological diagnosis
  • cytopathological diagnosis
  • definite diagnosis
  • definitive diagnosis
  • delayed diagnosis
  • dementia diagnosis
  • dependence diagnosis
  • depression diagnosis
  • diabetes diagnosis
  • different diagnosis
  • differential diagnosis
  • difficult diagnosis
  • disease diagnosis
  • disorder diagnosis
  • doctor diagnosis
  • dsm diagnosis
  • dsm-iii-r diagnosis
  • dsm-iv diagnosis
  • dual diagnosis
  • early diagnosis
  • early pregnancy diagnosis
  • early prenatal diagnosis
  • echocardiographic diagnosis
  • effective diagnosis
  • endoscopic diagnosis
  • environmental diagnosis
  • established diagnosis
  • exact diagnosis
  • failure diagnosis
  • false negative diagnosis
  • false positive diagnosis
  • false-negative diagnosis
  • false-positive diagnosis
  • faster diagnosis
  • fault diagnosis
  • final diagnosis
  • final histological diagnosis
  • firm diagnosis
  • first diagnosis
  • formal diagnosis
  • frequent diagnosis
  • gastrointestinal diagnosis
  • genetic diagnosis
  • hcc diagnosis
  • headache diagnosis
  • health diagnosis
  • histologic diagnosis
  • histological diagnosis
  • histological differential diagnosis
  • histopathologic diagnosis
  • histopathological diagnosis
  • hiv diagnosis
  • i diagnosis
  • icd-10 diagnosis
  • ii diagnosis
  • illness diagnosis
  • imaging diagnosis
  • immediate diagnosis
  • important diagnosis
  • important differential diagnosis
  • improved diagnosis
  • incorrect diagnosis
  • initial diagnosis
  • intraoperative diagnosis
  • invasive prenatal diagnosis
  • laboratory diagnosis
  • late diagnosis
  • lifetime diagnosis
  • likely diagnosis
  • lung cancer diagnosis
  • lymphoma diagnosis
  • major diagnosis
  • malignant diagnosis
  • md diagnosis
  • medical diagnosis
  • medicine diagnosis
  • melanoma diagnosis
  • mental health diagnosis
  • mental illness diagnosis
  • microbiological diagnosis
  • migraine diagnosis
  • missed diagnosis
  • molecular diagnosis
  • molecular prenatal diagnosis
  • morphological diagnosis
  • mri diagnosis
  • multiple diagnosis
  • nanda diagnosis
  • negative diagnosis
  • neuropathological diagnosis
  • new diagnosis
  • non-invasive diagnosis
  • noninvasive diagnosis
  • nursing diagnosis
  • objective diagnosis
  • one diagnosis
  • operational diagnosis
  • original diagnosis
  • other diagnosis
  • other psychiatric diagnosis
  • pathologic diagnosis
  • pathological diagnosis
  • patient diagnosis
  • pd diagnosis
  • personality disorder diagnosis
  • physical diagnosis
  • physician diagnosis
  • positive diagnosis
  • possible diagnosis
  • possible differential diagnosis
  • pre-implantation genetic diagnosis
  • pre-operative diagnosis
  • precise diagnosis
  • pregnancy diagnosis
  • preimplantation genetic diagnosis
  • preliminary diagnosis
  • prenatal diagnosis
  • preoperative diagnosis
  • presumed diagnosis
  • presumptive diagnosis
  • pretransplant diagnosis
  • previous diagnosis
  • primary diagnosis
  • principal diagnosis
  • prior diagnosis
  • probable diagnosis
  • prompt diagnosis
  • proper diagnosis
  • prostate cancer diagnosis
  • provisional diagnosis
  • psychiatric diagnosis
  • ptsd diagnosis
  • radiographic diagnosis
  • radiological diagnosis
  • rapid diagnosis
  • rapid prenatal diagnosis
  • real-time diagnosis
  • recent diagnosis
  • referral diagnosis
  • reliable diagnosis
  • routine diagnosis
  • same diagnosis
  • secondary diagnosis
  • serological diagnosis
  • sonographic diagnosis
  • species diagnosis
  • specific diagnosis
  • standard diagnosis
  • stroke diagnosis
  • subsequent diagnosis
  • surgical diagnosis
  • suspected diagnosis
  • tentative diagnosis
  • timely diagnosis
  • tissue diagnosis
  • tumor diagnosis
  • tumour diagnosis
  • ultrasonographic diagnosis
  • ultrasound diagnosis
  • underlying diagnosis
  • unequivocal diagnosis
  • urodynamic diagnosis
  • vivo diagnosis

  • Terms modified by Diagnosis

  • diagnosis being
  • diagnosis code
  • diagnosis difficult
  • diagnosis group
  • diagnosis groups
  • diagnosis other
  • diagnosis rate
  • diagnosis relate groups
  • diagnosis system
  • diagnosis tool

  • Selected Abstracts


    THREE CASES OF NODULAR FASCIITIS: PRIMARY DIAGNOSES BY FINE NEEDLE ASPIRATION CYTOLOGY

    CYTOPATHOLOGY, Issue 5 2001
    O. Aydin
    No abstract is available for this article. [source]


    CHANGE OF DIAGNOSES IN PROBABLE AND POSSIBLE MILD COGNITIVE IMPAIRMENT: THE ITALIAN LONGITUDINAL STUDY ON AGING

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 9 2007
    Vincenzo Solfrizzi MD
    No abstract is available for this article. [source]


    DIAGNOSIS AND CLINICAL COURSE OF ULCERATIVE GASTRODUODENAL LESION ASSOCIATED WITH ULCERATIVE COLITIS: POSSIBLE RELATIONSHIP WITH POUCHITIS

    DIGESTIVE ENDOSCOPY, Issue 4 2010
    Takashi Hisabe
    Background and Aim:, Ulcerative colitis (UC) is not only characterized by pathological lesions localized to colonic mucosa, but also to various complications involving other organs, including postoperative pouchitis. Among these complications, diffuse gastroduodenitis with lesions resembling colonic lesions has been reported, albeit rarely. The aim of the present study was to attempt to characterize the lesions of the upper gastrointestinal tract occurring as a complication of UC, and to assess the frequency and clinical course of these lesions. Methods:, A total of 322 UC patients who had undergone upper gastrointestinal endoscopy were retrospectively analyzed. We assessed the frequency of endoscopic findings, including diffuse gastroduodenal lesions resembling colonic lesions. Ulcerative gastroduodenal lesion (UGDL) associated with UC was diagnosed if lesions satisfied the following criteria: (i) improvement of the lesions with treatment of UC; and/or (ii) resemblance to UC in pathological findings. Results:, UGDL satisfying the aforementioned criteria was found in 15 (4.7%) of 322 patients. All the 15 patients had UGDL accompanied by pancolitis or after proctocolectomy. Frequency in 146 patients with pancolitis was 6.2% (nine patients) and that in 81 patients who had undergone proctocolectomy was 7.4% (six patients). Four patients with diffuse ulcerative upper-gastrointestinal mucosal inflammation (DUMI) had pouchitis. In all patients except one, the lesions resolved easily with medical treatment. Conclusions:, In more than half of the post-proctocolectomy patients, UGDL was related to the occurrence of pouchitis. The existence of characteristic UGDL must be taken into account in the diagnosis and treatment of UC, and UGDL is possibly related to the occurrence of pouchitis. [source]


    ENDOSCOPIC DEFINITION OF ESOPHAGOGASTRIC JUNCTION FOR DIAGNOSIS OF BARRETT'S ESOPHAGUS: IMPORTANCE OF SYSTEMATIC EDUCATION AND TRAINING

    DIGESTIVE ENDOSCOPY, Issue 4 2009
    Norihisa Ishimura
    The diagnosis of Barrett's esophagus (BE) requires an accurate recognition of the columnar-lined esophagus at endoscopy. However, a universally accepted standardized endoscopic grading system of BE was lacking prior to the development of the Prague ,circumferential and maximal' criteria. In this system, the landmark for the esophagogastric junction (EGJ) is the proximal end of the gastric folds, not the distal end of the palisade vessels, which are used to endoscopically identify the EGJ in Japan. Although the circumferential and maximal criteria are clinically relevant, an important shortcoming of this system may be failure to identify short-segment BE, a lesion that is found frequently in the Japanese. To compare the diagnostic yield for BE when using the palisade vessels versus gastric folds as a landmark for the EGJ, we evaluated interobserver diagnostic concordance. The endoscopic identification of the EGJ using both landmarks resulted in unacceptably low kappa coefficients of reliability. However, there was a statistically significant improvement after the participants were thoroughly trained in identification of the EGJ during the endoscopic study. Although it remains controversial which landmark is better for the endoscopic diagnosis of BE, it is important to systematically educate and train endoscopists in order to improve diagnostic consistency in patients with BE. [source]


    EARLY DIAGNOSIS OF SMALL PANCREATIC CANCER: ROLE OF ENDOSCOPIC ULTRASONOGRAPHY

    DIGESTIVE ENDOSCOPY, Issue 2009
    Atsushi Irisawa
    Advanced pancreatic cancer is a major cause of cancer-related death. However, if surgery achieves clear margins and negative lymph nodes, the prognosis for survival can be prolonged. Therefore, early diagnosis , as early as possible , is important for improving overall survival and quality of life in patients with pancreatic cancer. Because of higher imaging resolution near the pancreas through the gastroduodenal wall, endoscopic ultrasonography enables detection of subtle pancreatic abnormalities. In fact, many investigators have reported the high ability of EUS not only for detection of small lesions but also recognition of chronic pancreatitis, which is the risky status of pancreatic cancer. As a tool for early diagnosis of pancreatic cancer, EUS is a highly anticipated modality. [source]


    DIAGNOSIS OF COLONIC ADENOMAS BY NEW AUTOFLUORESCENCE IMAGING SYSTEM: A PILOT STUDY

    DIGESTIVE ENDOSCOPY, Issue 2007
    Noriya Uedo
    Detection and removal of adenoma by colonoscopy is an important means of preventing cancer. Autofluorescence endoscopy can visualize flat or isochromatic tumor that was not detectable by white light endoscopy by the difference in tissue fluorescence properties. Recently, a new autofluorescence imaging system (AFI, Olympus Medical Systems) using a combination of autofluorescence and reflection imaging has been developed. The purpose of the present paper was to investigate its feasibility in detection of colonic adenoma in a clinical setting. A total of 64 patients were randomly assigned to AFI or white light groups, and the distal sigmoid colon and the rectum was observed under autofluorescence or white light followed by the other mode of observation by a different endoscopist. The diagnostic ability of each method for detection of neoplasms was compared in relation to the histology as a reference standard. Sensitivity and specificity of AFI for detection of neoplastic polyps was 84% and 60%, respectively, and were similar to those of white light colonoscopy: 90% and 64%. Conventional colonoscopy overlooked more flat lesions including one adenocarcinoma. AFI has the potential to detect more flat lesions but efficacy was unable to be demonstrated in the restricted population. Further investigations are needed to determine optimum usage. [source]


    MAGNIFYING COLONOSCOPY FOR THE DIAGNOSIS OF INFLAMMATORY CHANGES IN ULCERATIVE COLITIS

    DIGESTIVE ENDOSCOPY, Issue 3 2006
    Satoshi Sugano
    Background:, Endoscopic observation is the most effective method for the evaluation of staging in ulcerative colitis (UC). However, in cases with very mild inflammatory activity, histopathological diagnosis may also be required. Unfortunately, biopsy-related accidents are not uncommon. As an alternative, we have used a magnifying colonoscope commonly used for tumor diagnosis to examine in detail the colon mucosa of UC patients in clinical remission, and then compared these findings relative to conventional endoscopy using histopathological diagnosis. Subjects and Methods:, Among UC cases examined by colonoscopy between April 2000 and April 2005, 27 cases without hematochezia for at least 1 month were enrolled in this study. Following observations of inflammatory changes using conventional colonoscopy, magnifying observation and biopsies at a total of 144 sites were evaluated. Using histopathological standards, acute-phase inflammation was indicated by the presence of neutrophil infiltration, whereas chronic-phase inflammation was indicated by infiltration of lymphocytes, plasma cells and eosinophils. Results:, Indicators of significant inflammation by conventional observation was erosion. Under magnification, inflammation appears as superficial defects in mucosa and small whitish spots. When the presence of infiltrating neutrophils was used as a positive histological marker for inflammation, there was no difference in the accuracy of diagnosis by conventional observation (95.1%) versus magnifying observation (97.2%). In contrast, when lymphocyte infiltration was used as a marker, the accuracy of diagnosis increased significantly (88.2%) using magnifying observation relative to conventional observation (61.1%). Conclusions:, Magnifying endoscopy can be used effectively in the evaluation of minute mucosal changes in cases of UC remission. [source]


    ENDOSCOPIC DIAGNOSIS OF INTRAEPITHELIAL SQUAMOUS NEOPLASIA IN HEAD AND NECK AND ESOPHAGEAL MUCOSAL SITES

    DIGESTIVE ENDOSCOPY, Issue 2006
    Manabu Muto
    In the multistep process of squamous epithelial carcinogenesis, squamous epithelial dysplasia has been considered to be a preinvasive stage of squamous cell carcinoma. If we could distinguish a dysplasia at high risk, such lesions could be targets for local treatment such as endoscopic mucosal resection to avoid the transformation to invasive carcinoma. Narrow-band imaging, a new optical technology, is useful to identify the cancerous lesion compared to conventional white light image. In addition, narrow-band imaging combined with magnifying endoscopy makes it possible to visualize the changes of microvascular architecture occurring in the epithelium. To evaluate whether these endoscopic findings are reliable to diagnose a dysplasia at high risk, a prospective study on the basis of the standards for reporting diagnostic accuracy initiative is needed. If endoscopic assessment of intraepithelial squamous neoplasia is reliable, it would be of benefit to the patients' outcome and improve cost effectiveness of care because of the avoidance of developing invasive carcinoma and the reduction of unnecessary biopsies. [source]


    WHAT KIND OF BENEFIT DO WE EXPECT FOR PERORAL PANCREATOSCOPY IN THE DIAGNOSIS OF INTRADUCTAL PAPILLARY MUCINOUS TUMOR OF THE PANCREAS?

    DIGESTIVE ENDOSCOPY, Issue 2006
    Taketo Yamaguchi
    Intraductal papillary mucinous tumor (IPMT) of the pancreas is characterized by slow growth and a relatively favorable prognosis, however, invasive cancer originating in an IPMT is associated with a poor prognosis. Although various parameters in imaging modalities have been advocated to differentiate between benign IPMN and malignant ones, it is not easy to obtain definite diagnosis based on these parameters. Peroral pancreatoscopy (POPS) allows a clear and direct visualization of the pancreatic duct, providing useful information regarding tumor nature in IPMT. The authors have studied the usefulness of POPS in the diagnosis of IPMT. Nevertheless, its usefulness is not necessarily widely accepted and the significance of POPS is still controversial. In this review, the authors intended to address the diagnostic value of POPS and to clarify its role in the diagnosis of IPMT. The authors think treatment of IPMT can be improved by introducing POPS because the determination of surgical procedure as well as the area of resection based on the preoperative diagnosis of the involvement of the main pancreatic duct and branch duct is inevitable. [source]


    ENDOSCOPIC TRANSPAPILLARY CATHETERIZATION INTO THE GALLBLADDER FOR DIAGNOSIS OF GALLBLADDER CARCINOMA

    DIGESTIVE ENDOSCOPY, Issue 2 2006
    Naohito Uchida
    It is often difficult to determine the precise nature of lesions in the gallbladder by radiographic, endoscopic and ultrasonographic methods. The approach to the gallbladder by a percutaneous transhepatic route has been reported. However, there is a possibility of seeding tumor cells into the peritoneal cavity and liver in a percutaneous procedure. On the contrary, transpapillary route can be performed without a possibility of seeding. The double-contrast cholecystography, intragallbladder sonography, direct biopsy of gallbladder lesions and cytology using gallbladder bile have been performed by the procedure of the transpapillary catheterization into the gallbladder. Confirming malignancy by histopathological diagnosis is desirous for determining therapeutic strategy in gallbladder carcinoma. Gathering gallbladder bile is comparatively easier than biopsy of the lesion using the transpapillary catheterization into the gallbladder. Examination of telomerase-related molecules is useful for diagnosis of pancreatic carcinoma. Usefulness of combination assay of human telomerase reverse transcriptase mRNA (hTERT mRNA) and cytology using gallbladder bile obtained by transpapillary catheterization is reported here. However, it would appear that hTERT mRNA is less important in the diagnosis of gallbladder carcinoma than in that of pancreatic carcinoma. When the molecular biological substances with higher sensitivity are found, the reliance of the combination assay of the molecular biological substances and cytology will be established. [source]


    BILIOPANCREATIC ENDOSCOPY FOR DIAGNOSIS and TREATMENT: WHAT IS NECESSARY TO STANDARDIZE BILIOPANCREATIC ENDOSCOPY IN JAPAN

    DIGESTIVE ENDOSCOPY, Issue 2002
    Hiroyuki Maguchi
    No abstract is available for this article. [source]


    EARLY GASTRIC CANCER: USEFULNESS OF INDEX OF HEMOGLOBIN ENHANCED IMAGING FOR THE DIAGNOSIS OF POORLY DIFFERENTIATED ADENOCARCINOMA

    DIGESTIVE ENDOSCOPY, Issue 2002
    Junko Fujisaki
    No abstract is available for this article. [source]


    MAGNIFYING ENDOSCOPY FOR THE DIAGNOSIS OF EARLY GASTRIC CANCER

    DIGESTIVE ENDOSCOPY, Issue 2002
    Yasumasa Niwa
    Magnifying endoscopy of stomach cancer requires observation of minute structure and minute vessel patterns of the mucosal surface. The small pits, various-sized pits, irregularly branched pits and irregular vessels were found to be characteristics as the surface structure of early gastric cancer. Small pits were commonly observed on the differentiated type of early gastric cancer (88%) compared with the undifferentiated type (50%). We found it important to analyze not only the minute vessel patterns, but also the minute surface structure to ensure magnifying endoscopic observation using 0.1% indigo-carmine and the binarized images would be effective in determining the margin of the lesion. The relationship between the findings of magnifying endoscopy in cancer and the histology should now be investigated. Applying the techniques mentioned above, more delicate observation in the regular endoscopy and prudent photographing to obtain clear images might be promoted. Thus, this would contribute to endoscopy with a concept similar to optical biopsy, and which can depend on the usual biopsy methods. [source]


    RECENT PROGRESS IN ENDOSCOPY-BASED DIAGNOSIS OF HELICOBACTER PYLORI INFECTION

    DIGESTIVE ENDOSCOPY, Issue 1 2001
    Tadashi Sato
    Numerous invasive and non-invasive tests are available in the detection of Helicobacter pylori. Endoscopy-based tests that include rapid urease test, histological examination and culture are important generally in the assessment of H. pylori status before eradication therapy. Recently, several new endoscopy-based diagnostic methods have been developed aiming at rapid and accurate detection of the organisms. It would be possible to diagnose H. pylori infection in treated patients by using these new highly sensitive tests. Although the diagnosis of H. pylori infection itself is possible by using non-invasive diagnostic tests, endoscopy-based tests provide not only the diagnosis of the organisms, but also the exclusive information such as treatment indications and the susceptibility for the antimicrobial drugs. Recently, new triple therapy including clarithromycin has been widely performed in Japan. Along with an increase in the prevalence of the antibiotic-resistant strains, culture may become a more important diagnostic method in the future. The inappropriate application of the tests may increase the potential risk of the misdiagnosis and the treatment failures. The diagnostic method should be selected by taking into account the circumstances in which a diagnosis is to be performed. [source]


    The effect of concurrent pain on the management of patients with depression: an analysis of NHS healthcare resource utilisation using the GPRD database

    INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 5 2009
    L. Watson
    Summary Introduction:, Patients with depression frequently report painful physical symptoms. However, there are scant data from the UK concerning differences in primary and secondary care resource use between depressed patients with and without pain treated in general practice. Methods:, Patients with depression codes were identified from the General Practice Research Database (GPRD) excluding those with psychoses. The observation period was 1st January 2000,31st December 2006. Patients were further categorised into three groups: (i) no painful physical symptom codes ever in the observation period (NO PAIN); (ii) patients with no other diagnostic or test codes 30 days either side of a pain code (PAIN MINUS DIAGNOSIS) and (iii) patients with pain codes and other diagnostic codes (PAIN PLUS DIAGNOSIS). Rates of general practitioner (GP) visits, antidepressant and concomitant prescribing and switching, secondary care referrals and diagnostic tests were reported per group with 95% confidence limits (CI). Results:, A total of 145,784 patients with depression aged 18,50 years were selected. Of these, 48,615 (33.3%) were classed as NO PAIN, the remaining 66.6% having pain. PAIN MINUS DIAGNOSIS patients constituted 5654 (5.8%) of those with pain. PAIN MINUS DIAGNOSIS and PAIN PLUS DIAGNOSIS had a significantly higher rate of GP visits than NO PAIN patients, 10.37 (95% CI 10.23, 10.52); 11.15 (11.11,11.20) and 7.04 (7.00, 7.08) respectively. Inter and intraclass drug switching was high with 13% of PAIN MINUS DIAGNOSIS and 14% of PAIN PLUS DIAGNOSIS patients having three or more switches compared with 7% of NO PAIN patients. Referral rates to secondary care were significantly higher in both pain groups compared with patients with no pain. Diagnostic testing was significantly greater in PAIN MINUS DIAGNOSIS and PAIN PLUS DIAGNOSIS groups than NO PAIN patients for all test types, with X-rays being the most common test; 3.85 (3.69,4.00); 2.77 (2.74,2.80); 0.91 (0.89, 0.94) respectively. Conclusion:, Patients in general practice diagnosed with depression and concurrent painful physical symptoms have higher resource use in primary and secondary care. [source]


    COGNITIVE SYNDROME OF THE THALAMUS: A MISLEADING DIFFERENTIAL DIAGNOSIS OF ALZHEIMER'S DISEASE

    JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 10 2008
    Emilie Beaufils MD
    No abstract is available for this article. [source]


    DEFINITIVE DIAGNOSIS OF EARLY ENAMEL AND DENTINAL CRACKS BASED ON MICROSCOPIC EVALUATION

    JOURNAL OF ESTHETIC AND RESTORATIVE DENTISTRY, Issue 7 2003
    Joel H. Berg DDS
    [source]


    OBTURATOR INTERNUS PYOMYOSITIS: A DIFFERENTIAL DIAGNOSIS FOR SEPTIC ARTHRITIS OF THE HIP

    JOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 9-10 2005
    Shobha Iyer MBBS
    No abstract is available for this article. [source]


    ANTI-SULFATIDE IgM ANTIBODIES DETECTED IN A PATIENT DIAGNOSIS OF MOTOR NEURON DISEASE

    JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, Issue 1 2002
    Article first published online: 11 MAR 200
    D'Avino C., Del Corona A., Bacci A., Calabrese R., Siciliano G. Department of Neuroscience-Clinical Neurology-University of Pisa-Italy Case report. The patient, a 66-year-old man with a 5-year diagnosis of diabetes mellitus, in Sep. 2000 started complaining of language disturbances as rhinolalia. In Jan. 2001, because of generalized fatigue and difficulties in walking, he was hospitalized in Internal Medicine and a diagnosis of diabetic angiopathy and neuropathy was made. Since discharge patient clinical conditions gradually deteriorated and a neurological evaluation showed tongue atrophy, dysarthria, dysphagia, fasciculations in the four limbs, increased deep tendon reflexes with bilateral foot clonus and paraparetic spastic deambulation. He underwent spinal MRI that showed mild arthrosic abnormalities in cervical spinal cord and limb EMG that showed denervation spontaneous activity with neurogenic MUAP modifications, with normal sensory and motor conduction velocity. MEP showed bilateral pyramidal track involvement. A significantly increased anti-sulphatide IgM antibodies titer (1:32,000) in the serum was detected. The diagnosis at discharge was "probable motor neuron disease" and the patient is under riluzole therapy at the moment. Discussion. Anti-sulfatide IgM antibodies are currently associated with several subtypes of peripheral neuropathy. In most cases it is a chronic dysimmune sensory or sensorimotor neuropathy in which electrophysiological and morphological studies are usually con- sistent with a predominant demyelination frequently associated with prominent axonal loss. Although rare, an association between motor neuron disease and IgM anti-sulfatide has been described in a recent paper by Latov and coworkers that reviewed electrophysiologic, morphologic and laboratory data of 25 patients with elevated antisulfatide antibodies. It seems interesting to follow-up the clinical course of the patient, the response to therapy and its correlation to antibodies titer, while the opportunity of high dose IVIg therapy is under discussion at the moment. [source]


    EPIDIDYMAL TUBERCULOSIS: PRESENTATIONS AND DIAGNOSIS

    ANZ JOURNAL OF SURGERY, Issue 6 2007
    Pranshu Bhargava MB BS
    No abstract is available for this article. [source]


    A CASE-BASED DECISION SUPPORT SYSTEM FOR INDIVIDUAL STRESS DIAGNOSIS USING FUZZY SIMILARITY MATCHING

    COMPUTATIONAL INTELLIGENCE, Issue 3 2009
    Shahina Begum
    Stress diagnosis based on finger temperature (FT) signals is receiving increasing interest in the psycho-physiological domain. However, in practice, it is difficult and tedious for a clinician and particularly less experienced clinicians to understand, interpret, and analyze complex, lengthy sequential measurements to make a diagnosis and treatment plan. The paper presents a case-based decision support system to assist clinicians in performing such tasks. Case-based reasoning (CBR) is applied as the main methodology to facilitate experience reuse and decision explanation by retrieving previous similar temperature profiles. Further fuzzy techniques are also employed and incorporated into the CBR system to handle vagueness, uncertainty inherently existing in clinicians reasoning as well as imprecision of feature values. Thirty-nine time series from 24 patients have been used to evaluate the approach (matching algorithms) and an expert has ranked and estimated similarity. On average goodness-of-fit for the fuzzy matching algorithm is 90% in ranking and 81% in similarity estimation that shows a level of performance close to an experienced expert. Therefore, we have suggested that a fuzzy matching algorithm in combination with CBR is a valuable approach in domains, where the fuzzy matching model similarity and case preference is consistent with the views of domain expert. This combination is also valuable, where domain experts are aware that the crisp values they use have a possibility distribution that can be estimated by the expert and is used when experienced experts reason about similarity. This is the case in the psycho-physiological domain and experienced experts can estimate this distribution of feature values and use them in their reasoning and explanation process. [source]


    Investigation of prolonged neonatal jaundice

    ACTA PAEDIATRICA, Issue 6 2000
    S Hannam
    Jaundice persisting beyond 14 d of age (prolonged jaundice) can be a sign of serious underlying liver disease. Protocols for investigating prolonged jaundice vary in complexity and the yield from screening has not been assessed. In order to address these issues, we carried out a prospective study of term infants referred to our neonatal unit with prolonged jaundice over an 18 mo period. Infants were examined by a paediatrician and had the following investigations: a total and conjugated serum bilirubin, liver function tests, full blood count, packed cell volume, group and Coombs' test, thyroid function tests, glucose-6-phosphate dehydrogenase levels and urine for culture. One-hundred-and-fifty-four infants were referred with prolonged jaundice out of 7139 live births during the study period. Nine infants were referred to other paediatric specialties. One infant had a conjugated hyperbilirubinaemia, giving an incidence of conjugated hyperbilirubinaemia of 0.14 per 1000 live births. Diagnoses included: giant cell hepatitis (n= 1), hepatoblastoma (n= 1), trisomy 9p (n= 1), urinary tract infections (n= 2), glucose-6-phosphate dehydrogenase deficiency (n= 3) and failure to regain birthweight (n= 1). Conclusions: In conclusion, a large number of infants referred to hospital for prolonged jaundice screening had detectable problems. The number of investigations may safely be reduced to: a total and conjugated bilirubin, packed cell volume, glucose-6-phosphate dehydrogenase level (where appropriate), a urine for culture and inspection of a recent stool sample for bile pigmentation. Clinical examination by a paediatrician has a vital role in the screening process. [source]


    Evaluation of Right Ventricular Fibrosis in Adult Congenital Heart Disease Using Gadolinium-enhanced Magnetic Resonance Imaging: Initial Experience in Patients with Right Ventricular Loading Conditions

    CONGENITAL HEART DISEASE, Issue 5 2006
    Lopa P. Hartke MD
    ABSTRACT Objective., Gadolinium-enhanced cardiac magnetic resonance imaging has been used to show myocardial fibrosis, a finding that appears as late gadolinium enhancement. Its role in the evaluation of right ventricular fibrosis in congenital heart disease is unclear. The purpose of this study was to demonstrate late gadolinium enhancement of the right ventricle in adult and adolescent congenital heart disease and to investigate the relationship between this enhancement and clinical and pathophysiological data. Design., In total, 24 patients, 16 patients with congenital heart disease and right ventricular loading conditions and 8 controls, underwent gadolinium-enhanced viability imaging. Diagnoses varied and included repaired, palliated, and unrepaired lesions. The presence and extent of right ventricular late gadolinium enhancement was compared with patient clinical and hemodynamic data. Exact Wilcoxon tests, Fisher's exact tests, and Spearman's rank correlation were used to compare variables. Results., Nine of 16 patients (56%) were found to have right ventricular late gadolinium enhancement, ranging from 5% to 80% of right ventricular myocardium affected (mean 36.1%, SD 29.7). The combination of right ventricular systolic pressure ,98 mm Hg and systemic oxygen saturation ,93% strongly suggested the presence of right ventricular late gadolinium enhancement (positive predictive value 100%), but no single variable or combination of variables could reliably predict its absence (negative predictive values ,75%). Extent of right ventricular late gadolinium enhancement did not correlate with degree of either hypoxia or right ventricular hypertension. Conclusions., Gadolinium-enhanced cardiac magnetic resonance demonstrates right ventricular late gadolinium enhancement in some patients with congenital heart disease and right ventricular loading conditions. Clinical variables were associated with the presence of fibrosis but did not reliably predict severity. Myocardial preservation is likely a multifactorial process that may affect the right and left ventricles differently. [source]


    Diagnoses at the first psychotic episode and cognitive functioning

    ACTA PSYCHIATRICA SCANDINAVICA, Issue 2002
    J. Addington
    Objectives, To determine the relationship between diagnosis and cognitive functioning in a first-episode sample. Methods, 175 subjects were diagnosed (SCID) on admission to a comprehensive treatment programme for early psychosis and 1 year later. Symptoms (PANSS), social functioning and cognitive functioning (using a comprehensive cognitive battery) were assessed initially and at 1 year. Subjects were divided into three groups: (1) Stable diagnosis of schizophrenia over 1 year (n=84). (2) Initial diagnosis of schizophreniform, brief psychotic disorder, substance induced psychosis or psychosis NOS but who met criteria for schizophrenia at 1 year (n=49) and (3) Stable diagnosis over 1 year of schizophreniform, brief psychotic disorder, substance induced psychosis or psychosis NOS (n=44). Results, There were significant differences amongst the three groups at both assessment periods in positive and negative symptoms and social functioning. There were no differences amongst the groups in cognitive functioning. Conclusions, Individuals with psychotic disorders who do not go on to develop schizophrenia do not differ significantly in neurocognition from those who do develop schizophrenia, although they may have advantages in other areas. [source]


    Smears diagnosed as ASCUS: Interobserver variation and follow-up

    DIAGNOSTIC CYTOPATHOLOGY, Issue 2 2001
    C.F.I.A.C., Rose Marie Gatscha S.C.T. (A.S.C.P.)
    Abstract The purpose of this study was to apply atypical squamous cells of undetermined significance (ASCUS) criteria from the Bethesda System for Reporting Cervical/Vaginal Cytologic Diagnoses (TBS) to the rescreen of cases previously diagnosed as ASCUS, to compare initial and rescreen diagnoses, and to analyze agreement with follow-up (cytology or histology). Two cytotechnologists (S.B. and M.J.M.) and one cytopathology fellow (M.A.) rescreened 632 cervicovaginal specimens diagnosed as ASCUS between June 1, 1992,December 31, 1995. Age and LMP were provided. Rescreen diagnoses were categorized as within normal limits (WNL), ASCUS, low-grade squamous intraepithelial lesions (LSIL), high-grade squamous intraepithelial lesions (HSIL), or carcinoma (CA). Complete agreement was found in 200 specimens (32%): 31 (15%) WNL; 91 (45%) ASCUS; 77 (38.5%) SIL; and one (0.50%) CA. Follow-up revealed no abnormality in 67% of the cases reclassified as WNL, 49% of the cases reclassified as ASCUS, and 48% of the cases reclassified as squamous intraepithelial lesions (SIL). SIL was found in 29% of cases reclassified as WNL, 29% of specimens rediagnosed as ASCUS, and 34% of cases reclassified as SIL. Partial agreement was found in 391 specimens (62%). In 41 specimens (6%), rescreeners were in complete disagreement, and follow-up revealed 9/41 (22%) SIL or worse; 21/41 (51%) WNL; and 4/41 (10%) inconclusive. Applying established criteria, 14% (91/632) of cases diagnosed as ASCUS resulted in complete agreement, and 30% (190/632) resulted in partial agreement. Follow-up of cases initially diagnosed as ASCUS revealed SIL or CA in 30% of cases. ASCUS is a significant diagnosis warranting careful patient follow-up. Diagn. Cytopathol. 2001;25:138,140. © 2001 Wiley-Liss, Inc. [source]


    Value of Transesophageal 3D Echocardiography as an Adjunct to Conventional 2D Imaging in Preoperative Evaluation of Cardiac Masses

    ECHOCARDIOGRAPHY, Issue 6 2008
    Silvana Müller M.D.
    Background: This study sought to compare three-dimensional (3D) and two-dimensional (2D) transesophageal echocardiography (TEE) to assess intracardiac masses. It was hypothesized that 3D TEE would reveal incremental information for surgical and nonsurgical management. Methods: In 41 patients presenting with intracardiac masses (17 thrombi, 15 myxomas, 2 lymphomas, 2 caseous calcifications of the mitral valve and one each of hypernephroma, hepatocellular carcinoma, rhabdomyosarcoma, lipoma, and fibroelastoma), 2D and 3D TEE were performed, aiming to assess the surface characteristics of the lesions, their relationship to surrounding structures, and attachments. Diagnoses were made by histopathology (n = 28), by computed tomography (n = 8), or by magnetic resonance imaging (n = 5). Benefit was categorized as follows: (A) New information obtained through 3D TEE; (B) helpful unique views but no additional findings compared to 2D TEE; (C) results equivalent to 2D TEE; (D) 3D TEE missed 2D findings. Results: In 15 subjects (37%), 3D TEE revealed one or more items of additional information (category A) regarding type and site of attachment (n = 9, 22%), surface features (n = 6, 15%), and spatial relationship to surrounding structures (n = 8, 20%). In at least 18% of all intracardiac masses, 3D TEE can be expected to deliver supplementary information. In six patients, additional findings led to decisions deviating from those made on the basis of 2D TEE. In 11 subjects (27%), 3D echocardiographic findings were categorized as "B." Conclusions: Information revealed by 3D imaging facilitates therapeutic decision making and especially the choice of an optimal surgical access prior to removal of intracardiac masses. [source]


    Lispe patellitarsis Becker (Diptera: Muscidae) new to Korea

    ENTOMOLOGICAL RESEARCH, Issue 4 2009
    Sang Jae SUH
    Abstract Lispe patellitarsis Becker is identified for the first time in Korea. Diagnoses and illustrations of the habitus and male genitalia are given. [source]


    Autalia rivularis (Gravenhorst) and Brachida clara (Weise) new to Korea (Coleoptera: Staphylinidae: Aleocharinae)

    ENTOMOLOGICAL RESEARCH, Issue 2 2008
    Yoon-Ho KIM
    Abstract Two aleocharine species, Autalia rivularis (Gravenhorst) and Brachida clara (Weise), are identified for the first time in Korea. Diagnoses, habitus illustrations, and line drawings of diagnostic characters are provided. [source]


    First records of Leiodytes nicobaricus (Redtenbacher) and Platambus stygius (Régimbart) in Korea (Coleoptera: Dytiscidae)

    ENTOMOLOGICAL RESEARCH, Issue 1 2008
    Dae-Hyun LEE
    Abstract Two dytiscid beetle species, Leiodytes nicobaricus (Redtenbacher) and Platambus stygius (Régimbart), are identified for the first time in Korea. Diagnoses, habitus and scanning electron microscopy photographs, and line drawings of the diagnostic characters are provided. [source]


    Three littoral Athetini (Coleoptera: Staphylinidae: Aleocharinae) species new to Korea

    ENTOMOLOGICAL RESEARCH, Issue 3 2007
    Jong-Seok PARK
    Abstract Three littoral Athetini species ,Adota magnipennis (Bernhauer), Atheta ririkoae Sawada and Atheta tokiokai (Sawada) , are reported for the first time in Korea. Diagnoses, illustrations of the habitus and line drawings of diagnostic characters are provided. [source]