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Dimer Complex (dimer + complex)
Selected AbstractsEvolution of O2 in a Seven-Coordinate RuIV Dimer Complex with a [HOHOH], Bridge: A Computational Study,ANGEWANDTE CHEMIE, Issue 10 2010Jonas Nyhlén Das fehlende Glied? Nach DFT-Rechnungen ist ein Mechanismus der O2 -Entwicklung unter Beteiligung zweikerniger, siebenfach koordinierter Rutheniumspezies wahrscheinlich, bei dem Sauerstoffradikale direkt gekuppelt werden und keine unüberwindlich hohen Potentialenergiebarrieren im Wege stehen (siehe Schema). [source] ChemInform Abstract: Sandwich Dimer Complexes of Zinc Porphyrins Bearing Three-Dimensionally Oriented Redox-Active ,-Conjugated Pendant Groups.CHEMINFORM, Issue 26 2002Toshikazu Hirao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Conformational Flexibility in a Carbobicyclic Diphosphinite LigandEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 20 2007Ian J. S. Fairlamb Abstract An unsymmetrical bicyclo[3.2.0]heptanyl diphosphinite ligand, FLEXIphosO, shows flexible coordination modes to palladium centres. The X-ray crystal structure for [Pd02(P,P,)3] has been determined which reveals that the bicyclic backbone of the FLEXIphosO ligand exists in an exo -envelope conformation. The change in conformation stands in stark contrast to that observed in mononuclear neutral and cationic palladium(II) complexes containing the FLEXIphosO ligand, where an endo -envelope is observed in solution and in the solid-state. Theoretical studies provide an insight into the relative stability of palladium(0) complexes containing the FLEXIphosO ligand. Another large spanning angle ligand, SPANphos, does not form a similar palladium(0) dimer complex under identical reaction conditions, highlighting the unusual behaviour of the FLEXIphosO ligand.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] Nuclear factor-,b activation is associated with glutamate-evoked tissue transglutaminase up-regulation in primary astrocyte culturesJOURNAL OF NEUROSCIENCE RESEARCH, Issue 6 2005Daniela Caccamo Abstract We have previously demonstrated that alterations of cell redox state, evoked by glutamate, are associated with tissue transglutaminase increases in primary astrocyte cultures. Furthermore, glutamate exposure activated the nuclear factor (NF)-,B pathway, and its effects were significantly reduced by antioxidants. Here, we investigated the possible involvement of activated NF-,B pathway in glutamate-evoked tissue transglutaminase up-regulation in primary astrocytes. The presence of DNA binding activity by NF-,B in nuclear extracts of astrocytes, treated for 24 hr with glutamate (500 ,M) or untreated, was assessed by EMSA, using an oligonucleotide probe containing the NF-,B consensus sequence present in the tissue transglutaminase promoter. Supershifting with monoclonal antibodies revealed that activated NF-,B dimer complexes were composed of p50 and p65 subunits. Interestingly, the specific NF-,B inhibitor SN50 (but not its inactive analogue SN50M), when added to cell cultures 30 min prior to glutamate treatment, was able gradually to reduce glutamate-induced NF-,B activation. Western blot analysis confirmed the reduction of the p50 amount in nuclear extracts. Notably, the preincubation with SN50 also diminished glutamate-increased tissue transglutaminase expression, as showed by both RT-PCR and Western blotting. Competition experiments, carried out with an excess of a probe containing the NF-,B consensus sequence present in the ,-light-chain promoter, demonstrated a preferential binding of the tissue transglutaminase specific NF-,B probe in the nuclear extracts of glutamate-treated astrocytes compared with untreated astrocytes. These preliminary data suggest that NF-,B activation, which has been demonstrated to be involved in astrocyte response to glutamate, could also be associated with the molecular pathway leading to glutamate-evoked tissue transglutaminase up-regulation. © 2005 Wiley-Liss, Inc. [source] | ||||||||||