Home About us Contact | |||
Device Consisting (device + consisting)
Selected AbstractsMultilevel Biomemory Device Consisting of Recombinant Azurin/Cytochrome cADVANCED MATERIALS, Issue 4 2010Taek Lee A multilevel biomemory device displays two pairs of nonvolatile write, read, and erase functions (see figure). The device consists of recombinant azurin/cytochrome c. Azurin is recombined with a cysteine residue to enhance the stability of the self-assembled protein on a gold surface. Then, cytochrome c is adsorbed onto the immobilized azurin layer. The verified memory characteristic of the proposed device implies that the metalloprotein is a very promising molecule for the development of a new type of memory device. [source] A micropillar-integrated smart microfluidic device for specific capture and sorting of cellsELECTROPHORESIS, Issue 24 2007Yan-Jun Liu Abstract An integrated smart microfluidic device consisting of nickel micropillars, microvalves, and microchannels was developed for specific capture and sorting of cells. A regular hexagonal array of nickel micropillars was integrated on the bottom of a microchannel by standard photolithography, which can generate strong induced magnetic field gradients under an external magnetic field to efficiently trap superparamagnetic beads (SPMBs) in a flowing stream, forming a bed with sufficient magnetic beads as a capture zone. Fluids could be manipulated by programmed controlling the integrated air-pressure-actuated microvalves, based on which in situ bio-functionalization of SPMBs trapped in the capture zone was realized by covalent attachment of specific proteins directly to their surface on the integrated microfluidic device. In this case, only small volumes of protein solutions (62.5,nL in the capture zone; 375,nL in total volume needed to fill the device from inlet A to the intersection of outlet channels F and G) can meet the need for protein! The newly designed microfluidic device reduced greatly chemical and biological reagent consumption and simplified drastically tedious manual handling. Based on the specific interaction between wheat germ agglutinin (WGA) and N -acetylglucosamine on the cell membrane, A549 cancer cells were effectively captured and sorted on the microfluidic device. Capture efficiency ranged from 62 to 74%. The integrated microfluidic device provides a reliable technique for cell sorting. [source] Hybrid Nanoparticle/Organic Devices with Strong Resonant Tunneling BehaviorsADVANCED FUNCTIONAL MATERIALS, Issue 16 2009Tianhang Zheng Abstract A hybrid nanoparticle/organic device consisting of small molecule organic semiconductors and Ag nanoparticles is reported. The single device exhibits unusual properties of organic resonant tunneling diode (ORTD) at low driving voltage region and offers light emission at high voltage. For ORTD, a strong negative differential resistance behavior is demonstrated at room temperature. The current resonance with the peak-to-valley current ratio of over 4.6 and narrow linewidth of only ,1.4,V is achieved. A detailed operating mechanism of the charging and emission modes is proposed, which can be discussed in terms of the strong charge-trapping effect of Ag nanoparticles. The repeatable operations of hybrid device show the mutual influences between two modes and the light emission properties of the ORTD are also discussed. [source] Increased Color-Conversion Efficiency in Hybrid Light-Emitting Diodes utilizing Non-Radiative Energy TransferADVANCED MATERIALS, Issue 5 2010Soontorn Chanyawadee An efficient hybrid color-conversion light-emitting device consisting of colloidal nanocrystal quantum dots (NQDs) and a surface-patterned GaN-based LED is demonstrated (see figure). Excitation in a surface-patterned LED is efficiently transferred to NQD emitters via non-radiative energy transfer. A twofold enhancement of the NQD emission is achieved. [source] A Family of Electronically Reconfigurable NanodevicesADVANCED MATERIALS, Issue 37 2009J. Joshua Yang AFM image of 17 nanodevices with a zoom-in cartoon schematically shows an individual crosspoint device consisting of two Pt metal electrodes separated by a TiO2 bi-layer memristive material. By applying an electric field across the memristive material, oxygen vacancies can drift up and down, leading to four current-transport end-states. The switching between these end-states results in a family of nanodevices. [source] Redox-Active Polypyrrole: Toward Polymer-Based Batteries,ADVANCED MATERIALS, Issue 13 2006H.-K. Song An energy-storage device consisting of polypyrrole (pPy) doped with indigo carmine (IC) and 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonate) (ABTS) has been fabricated. These redox-active conducting polymers (see figure) form the basis of a battery that depends on the faradaic reactions of the redox-active dopants, and performs better than conventional batteries and ultracapacitors at high power density. [source] Measuring masticatory performance using a new device and ,-carotene in test gummy jellyJOURNAL OF ORAL REHABILITATION, Issue 11 2010T. NOKUBI Summary, Objective methods for evaluating masticatory performance are invaluable for quantitative comparisons between various dental treatments as well as diagnosing masticatory disorder. The purpose of this study was to develop an accurate method for automatically measuring masticatory performance using a new measuring device consisting of light-emitting diodes and a photodiode and test gummy jelly. First, the relationship between six known ,-carotene concentrations in aqueous solution and the voltage values exhibited on a photodiode was investigated. Mean voltage obtained by red light incident on the photodiode indicated a significantly high correlation (r = 0·999 in a cubic function, P < 0·01) with ,-carotene concentration in the aqueous solution. Second, to establish the optimal measuring conditions for evaluating masticatory performance, factors influencing mean voltage were investigated, such as water temperature and times for rinsing the gummy jelly and dissolving ,-carotene from the jelly. A stable mean voltage was obtained by measuring under the following conditions: rinsing water temperature, 35 °C; rinsing time, 30 s; water dissolving temperature, 35 °C; dissolving time, 10 s. Finally, the relationship between seven surface area values of divided gummy jelly and ,-carotene concentrations dissolved from the divided jellies was investigated. The increase in surface area of divided test gummy jelly particles was accurately calculated (r = 0·992, P < 0·001) from mean voltage on the photodiode to change with ,-carotene concentration dissolved from the jelly surface. This new method using test gummy jelly and an automatic measuring device appears useful for precisely evaluating masticatory performance. [source] Percutaneous transtracheal emergency ventilation with a self-made device in an animal modelPEDIATRIC ANESTHESIA, Issue 10 2007RAIK SCHAEFER Summary Background:, Special equipment for emergency percutaneous transtracheal ventilation is often not immediately available. We used a self-made device consisting of a three-way stopcock connected between a G-15 transtracheal airway catheter and an oxygen supply in a simulated 'cannot intubate, cannot ventilate' scenario and tested the hypothesis that the effectiveness of the device depends on the body weight of the experimental animals. Methods:, With approval of the local animal protection committee, two groups of six pigs each with a body weight of 21 ± 2 and 36 ± 6 kg, respectively, were tracheally intubated and mechanically ventilated after induction of anesthesia. Hemodynamic monitoring included cardiac output and arterial, central venous and pulmonary artery pressures. An emergency transtracheal airway catheter was inserted into the trachea and a situation of partial expiratory airway obstruction was created. Each animal was ventilated for 15 min via the transtracheal airway catheter with the self-made device (FiO2 1.0 at an oxygen flow of 15 l·min,1; respiratory rate of 60 min,1; I/E ratio approximately 1 : 1). Results:, Whereas satisfactory oxygenation was achieved in all animals, sufficient ventilation was obtained only in the lightweight animals. Conclusions:, Adequate oxygenation could be provided by jet-like transtracheal ventilation with a simple self-made device using easily available materials. Sufficient ventilation depends on the body weight of the animals. [source] Efficient UV detection of protein crystals enabled by fluorescence excitation at wavelengths longer than 300,nmACTA CRYSTALLOGRAPHICA SECTION F (ELECTRONIC), Issue 4 2010Karsten Dierks It is well known that most proteins and many other biomolecules fluoresce when illuminated with UV radiation, but it is also commonly accepted that utilizing this property to detect protein crystals in crystallization setups is limited by the opacity of the materials used to contain and seal them. For proteins, this fluorescence property arises primarily from the presence of tryptophan residues in the sequence. Studies of protein crystallization results in a variety of setup configurations show that the opacity of the containment hardware can be overcome at longer excitation wavelengths, where typical hardware materials are more transparent in the UV, by the use of a powerful UV-light source that is effective in excitation even though not at the maximum of the excitation response. The results show that under these circumstances UV evaluation of crystallization trials and detection of biomolecular crystals in them is not limited by the hardware used. It is similarly true that a deficiency in tryptophan or another fluorescent component that limits the use of UV light for these purposes can be effectively overcome by the addition of fluorescent prostheses that bind to the biomolecule under study. The measurements for these studies were made with a device consisting of a potent UV-light source and a detection system specially adapted (i) to be tunable via a motorized and software-controlled absorption-filter system and (ii) to convey the excitation light to the droplet or capillary hosting the crystallization experiment by quartz-fibre light guides. [source] Rapid and selective isolation of ,-xylosidase through an activity-based chemical approachBIOTECHNOLOGY JOURNAL, Issue 2 2006Lee-Chiang Lo Dr. Abstract ,-Xylosidase is a key enzyme in the xylanolytic system with a great potential in many biotechnological applications, especially in the food as well as the pulp and paper industries. We have developed a chemical approach for the rapid screening and isolation of ,-xylosidase. Activity probe LCL-6X targeting ,-xylosidase was utilized in this study. It carries a ,-xylopyranosyl recognition head, a latent trapping device consisting of a 2-fluoromethylphenoxyl group, and a biotin reporter group. The biotin reporter group serves both as a readout device and as a tool for enriching the labeled proteins. LCL-6X could selectively label a model ,-xylosidase from Trichoderma koningii. All other bystander proteins used in this study, including phosphorylase b, BSA, ovalbumin, carbonic anhydrase, and trypsin inhibitor, gave negligible cross-labeling effect. With the assistance of streptavidin agarose beads and mass spectrophotometry for the recovery and identification of the biotinylated proteins, we demonstrated that LCL-6X could be successfully applied to identify a bi-functional enzyme with ,- L -arabinofuranosidase/,-xylosidase activity from the total protein extract of a Pichia expressing system and a prospective ,-xylosidase in the culture medium of Aspergillus fumigatus. The ,-xylosidase activities from numerous microbes were also screened using the LCL-6X probe. Preliminary results showed significant differences among these microbial sources and some distinct protein bands were observed. Thus, we have successfully developed a novel chemical probe that has potential applications in xylan-related research. [source] Rewritable Switching of One Diode,One Resistor Nonvolatile Organic Memory DevicesADVANCED MATERIALS, Issue 11 2010Byungjin Cho One diode,one resistor (1D,1R) hybrid-type devices consisting of an inorganic Schottky diode and an organic unipolar memory show electrically rewritable switching characteristics as well as rectifying properties. The 1D,1R array architecture improves the sensing efficiency of the array memory cell, ultimately creating the possibility for high-density integrated organic memory devices without restrictions due to cross-talk between cells. [source] Modulation of dynamic release of vitamin B2 from a model pH-sensitive terpolymeric hydrogel systemPOLYMER INTERNATIONAL, Issue 12 2004Dr SK Bajpai Abstract Terpolymeric devices consisting of acrylamide, methacrylamide and acrylic acid were synthesized and the release of the model drug riboflavin from these devices was studied at the physiological temperature 37°C. The gels exhibit a sharp pH-dependent release behavior. The devices released nearly 42.2 ± 2.6% drug at pH 1.0 while nearly 95.3 ± 3.2% drug was released at pH 7.4. With increasing concentration of cross-linker in the gel, the drug released was found to decrease. Moreover, with low content of cross-linker a nearly zero-order profile was obtained. The size of the cylindrical devices also affected the release kinetics and a linear dependency was observed between t1/2 (ie, the time required for 50 % release) and the square of the diameter, thus supporting the Tanaka,Fillmore theory. The molar ratio of acrylamide and methacrylamide also affected the dynamic release of riboflavin. It was found that variation in transit time could also affect the drug-releasing capacity of the devices. Finally, the average and ,late-time' diffusion coefficients for the gels having different initial loads were also evaluated. Copyright © 2004 Society of Chemical Industry [source] |