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Terms modified by Developed Selected AbstractsInvesting Public Pensions in the Stock Market: Implications for Risk Sharing, Capital Formation and Public Policy in the Developed and Developing WorldINTERNATIONAL REVIEW OF FINANCE, Issue 3 2001Deborah Lucas Concerns that existing public pension systems will be unable to pay benefits to a rapidly ageing population without sharp tax increases, and the prospect of higher average returns on stocks than on government securities, are drawing the attention of policy,makers worldwide to the option of investing public pension assets in stocks. Including stock market investments in public pension plans could improve risk sharing within and between generations, and could perhaps lead to faster market development in some countries. It could also result in excessive risk,taking, higher transactions costs and a false sense of increased financial security. This paper assesses these issues, with an emphasis on the considerations that are of special importance to developing markets. A contrast is drawn between the demographic outlook in East Asia and the major industrialized countries. Some lessons are drawn from the reform experience in Chile and elsewhere in Latin America. [source] Heterogeneous Plasma-Producing Structures at Current Implosion of a Wire ArrayCONTRIBUTIONS TO PLASMA PHYSICS, Issue 8 2005E. V. Grabovsky Abstract Characteristic properties of the plasma production process have been considered for the case of megampere currents flowing through hollow cylindrical wire arrays of the Angara-5-1 facility. In 3-4 nanoseconds after voltage applying to the wire surfaces there appear a plasma layer. The system becomes heterogeneous, i.e. consisting of a kernel of metal wires and a plasma layer. In several nanoseconds the current flow goes from metal to plasma, which results in reducing the electric field strength along the wire. The Joule heat energy delivered to the metal before the moment of complete current trapping by plasma is insufficient for the whole mass transition to a hot plasma state. The X-ray radiography techniques made it possible to detect and study dense clusters of substance of ,1g/cm3 at a developed discharge stage. The radial expansion velocity of ,104 cm/s measured at the 70-th nanosecond after the current start allows treating the dense core at a late stage in the form of a submicron heterogeneous structure from its liquid and slightly ionized gas phase. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Pigmentary Changes After Alexandrite Laser Hair RemovalDERMATOLOGIC SURGERY, Issue 4 2003Noah Kawika Weisberg MD Background Postinflammatory pigmentary changes are a frequently encountered problem with numerous dermatologic procedures. Limited literature is available that documents this complication with laser hair removal. Objective It is important for all physicians performing laser hair removal to be aware of this potential complication. We present our experience with postinflammatory pigmentary change and discuss some potential etiologic factors. Methods Seven patients who experienced postinflammatory complications after alexandrite laser hair removal are presented. These are all the patients who developed this complication in our office over the past 2.5 years. Results The patients who we describe in this article all developed a similar pattern of initial hyperpigmented rings, later developing into a thin wafer-like crust followed by hypopigmentation with gradual return to their normal skin color. Conclusion In general, the alexandrite laser is both safe and effective for hair removal in patients of varying skin types. Complication rates will increase as skin pigment increases and as the power used increases. However, even in light-skinned individuals without recent pretreatment or posttreatment sun exposure, with proper treatment parameters, complications, and side effects can arise. We have found this to be especially true when treating areas other than the face. [source] The therapeutic relationship in secondary mental health care: a conceptual review of measuresACTA PSYCHIATRICA SCANDINAVICA, Issue 4 2007J. Catty Objective: The study aimed to determine the conceptual basis of measures of the patient,professional relationship used in routine mental health services research by reviewing their face, content and construct validity. Method: A comprehensive literature search identified measures of the relationship used in mental health services research. The conceptual basis of each identified measure was identified by a review of measures' authors assessments of face, content and construct validity plus item analysis of the measures themselves. Results: The search identified 15 measures. The seven developed in psychotherapy were likely to be better validated conceptually; most were based on therapeutic alliance models. Measures developed specifically for mental health services were based on a wider range of models including global assessments of the relationship. Conclusion: Most of the better validated measures originate in psychotherapy, but there is limited evidence for their validity in general mental health services. Four measures are recommended. [source] Decline of neuroadrenergic bronchial innervation and respiratory function in type 1 diabetes mellitus: a longitudinal studyDIABETES/METABOLISM: RESEARCH AND REVIEWS, Issue 4 2007Raffaele Antonelli Incalzi Abstract Background and aim Type 1 diabetes mellitus complicated by autonomic neuropathy (AN) is characterized by depressed cholinergic bronchomotor tone and neuroadrenergic denervation of the lung. We explored the effects of AN on the rate of decline of pulmonary sympathetic innervation and respiratory function during a 5-year follow-up. Methods Twenty diabetic patients, 11 with AN, were enrolled in 1998 and then followed-up until 2003. During follow-up, glycosylated haemoglobin (HbA1c) was measured every 3 months. In 1998 and 2003 the patients underwent respiratory function tests and a ventilatory scintigraphic study of neuroadrenergic bronchial innervation using 123I-MIBG. Results During follow-up 4 patients, all with AN, were lost, and 1 developed AN. Forced vital capacity (FVC), and diffusing capacity of the lung for carbon monoxide (DLCO) showed comparable rates of decrease in patients with and without AN. The yearly decline of forced expiratory volume in 1 s (FEV1) was about double the physiologic rate, in both AN and AN-free patients. The MIBG clearance significantly increased both in patients with AN (T1/2: 118.88 ± 30.14 min at baseline and 92.10 ± 24.52 min at the end of follow-up) and without AN (135.14 ± 17.09 min and 92.68 ± 13.52 min, respectively), indicating a rapidly progressive neuroadrenergic denervation. The rate of the neuroadrenergic denervation was inversely related to the severity of autonomic dysfunction at baseline (Spearman's rho , 0.62, p = 0.017). Neither respiratory function indexes nor MIBG clearance changes correlated with the overall HbA1c values. Conclusions Neuroadrenergic denervation of the lung parallels the decline of respiratory function indexes in diabetic patients both with and without AN and seems to be independent from the quality of glycemic control. Copyright © 2006 John Wiley & Sons, Ltd. [source] International Diabetes Federation: a consensus on Type 2 diabetes preventionDIABETIC MEDICINE, Issue 5 2007K. G. M. M. Alberti Abstract Aims, Early intervention and avoidance or delay of progression to Type 2 diabetes is of enormous benefit to patients in terms of increasing life expectancy and quality of life, and potentially in economic terms for society and health-care payers. To address the growing impact of Type 2 diabetes the International Diabetes Federation (IDF) Taskforce on Prevention and Epidemiology convened a consensus workshop in 2006. The primary goal of the workshop and this document was the prevention of Type 2 diabetes in both the developed and developing world. A second aim was to reduce the risk of cardiovascular disease in people who are identified as being at a higher risk of Type 2 diabetes. The IDF plan for prevention of Type 2 diabetes is based on controlling modifiable risk factors and can be divided into two target groups: ,,People at high risk of developing Type 2 diabetes ,,The entire population. Conclusions, In planning national measures for the prevention of Type 2 diabetes, both groups should be targeted simultaneously with lifestyle modification the primary goal through a stepwise approach. In addition, it is important that all activities are tailored to the specific local situation. Further information on the prevention of diabetes can be found on the IDF website: http://www.idf.org/prevention. [source] Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: a realistic viewDIABETIC MEDICINE, Issue 9 2003P. Zimmet The last two decades have seen an explosive increase in the number of people with diabetes globally. There is now an urgent need for strategies to prevent the emerging global epidemic. Several recent successful intervention studies, both lifestyle and pharmacological, targeting subjects with impaired glucose tolerance (IGT) have stimulated enthusiasm for prevention of Type 2 diabetes. Lifestyle interventions reduced the incidence of diabetes by over 50% in the Finnish Diabetes Prevention Study and the Diabetes Prevention Program. Can the findings of these two studies be applied globally? Underpinning the enthusiasm, there needs to be a realistic approach to interventions in both developed and developing nations, and in ethnic groups where a better understanding of the socio-economic, cultural and demographic issues and perceptions surrounding chronic diseases such as diabetes is required. Whether the strategies used in these two studies can be translated into a ,real world' scenario is doubtful. In practice, it is more than likely that a number of strategies will be needed to compliment the lifestyle approach. These will include pharmacological approaches with metformin, acarbose and other agents used to treat diabetes and its complications, currently under investigation. Longer-term follow-up studies will also clarify whether both lifestyle and pharmacological interventions actually prevent Type 2 diabetes, or merely delay its onset. [source] The fine needle aspiration biopsy diagnostic criteria of proliferative breast lesions: A retrospective statistical analysis of criteria for papillomas and radial scar lesionsDIAGNOSTIC CYTOPATHOLOGY, Issue 7 2007Andrew Field F.R.C.P.A. Abstract This study aimed to analyze statistically the accuracy of fine needle aspiration biopsy cytological criteria in diagnosing epithelial hyperplasia with atypia (EHA), papillary lesions (PAP), and radial scar/complex sclerosing lesions (RS/CSL). The 42 criteria studied were extracted from a literature review and those developed and used in our department. Cytological cases with diagnoses of EHA, PAP, and RS/CSL for the period of 1997,2001 were correlated with relevant histological follow-up and the positive predictive power of these diagnoses have been presented in an earlier publication. Some 77 cases with definite, specific histological diagnoses of atypia or a more severe lesion, PAP and RS/CSL, were reviewed and scored using 55 cytological criteria. As the group of EHA and RS/CSL yielded a smaller number of cases, these were grouped together in the statistical analysis and compared to PAP. The cytological features, which were most diagnostic for PAP, were stellate (Odds ratio 1.75) and meshwork (Odds ratio 3.29) tissue fragments, while the presence of tubular structures was inversely proportional to the histological outcome of PAP. True papillary fragments were uncommon and not statistically significant in diagnosing PAP of the breast. Diagn. Cytopathol. 2007;35:386,397. © 2007 Wiley-Liss, Inc. [source] Alcohol and injuries: a review of international emergency room studies since 1995DRUG AND ALCOHOL REVIEW, Issue 2 2007CHERYL J. CHERPITEL Abstract This paper provides a review of emergency room (ER) studies on alcohol and injury, using representative probability samples of adult injury patients, and focuses on the scope and burden of the problem as measured by estimated blood alcohol concentration (BAC) at the time of the ER visit, self-report drinking prior to injury, violence-related injury and alcohol use disorders. A computerized search of the English-language literature on MEDLINE, PsychINFO and the National Institute on Alcohol Abuse and Alcoholism (NIAAA) Alcohol and Alcohol Problems Science Database (ETOH) was conducted for articles published between 1995 and 2005, using the following key descriptors: (1) emergency room/emergency department/accident and emergency, (2) alcohol/drinking and (3) injuries (intentional and unintentional). Findings support prior reviews, with injured patients more likely to be positive for BAC and report drinking prior to injury than non-injured, and with the magnitude of the association substantially increased for violence-related injuries compared to non-violence-related injuries. Indicators of alcohol use disorders did not show a strong association with injury. Findings were not homogeneous across studies, however, and contextual variables, including study-level detrimental drinking pattern, explained some of the variation. This review represents a broader range of ER studies than that reported previously, across both developed and developing countries, and has added to our knowledge base in relation to the influence of contextual variables on the alcohol-injury relationship. Future research on alcohol and injury should focus on obtaining representative samples of ER patients, with special attention to both acute and chronic alcohol use, and to organisational and socio-cultural variables that may influence findings across studies. In-depth patient interviews may also be useful for a better understanding of drinking in the injury event and associated circumstances. [source] Experimental study of rill bank collapseEARTH SURFACE PROCESSES AND LANDFORMS, Issue 2 2007Jovan R. Stefanovic Abstract Rill bank collapse is an important component in the adjustment of channel morphology to changes in discharge and sediment flux. Sediment inputs from bank collapse cause abrupt changes in flow resistance, flow patterns and downstream sediment concentrations. Generally, bank retreat involves gradual lateral erosion, caused by flow shear stress, and sudden bank collapse, triggered by complex interactions between channel flow and bank and soil water conditions. Collapse occurs when bank height exceeds the critical height where gravitational forces overcome soil shear strength. An experimental study examined conditions for collapse in eroding rill channels. Experiments with and without a deep water table were carried out on a meandering rill channel in a loamy sand and sandy loam in a laboratory flume under simulated rainfall and controlled runon. Different discharges were used to initiate knickpoint and rill incision. Soil water dynamics were monitored using microstandpipes, tensiometers and time domain reflectometer probes (TDR probes). Bank collapse occurred with newly developed or rising pre-existing water tables near rill banks, associated with knickpoint migration. Knickpoint scour increased effective bank height, caused positive pore water pressure in the bank toe and reduced negative pore pressures in the unsaturated zone to near zero. Matric tension in unsaturated parts of the bank and a surface seal on the ,interrill' zone behind the bank enhanced stability, while increased effective bank height and positive pore water pressure at the bank toe caused instability. With soil water contents >35 per cent (sandy loam) and >23 per cent (loamy sand), critical bank heights were 0·11,0·12 m and 0·06,0·07 m, respectively. Bank toe undercutting at the outside of the rill bends also triggered instability. Bank displacement was quite different on the two soils. On the loamy sand, the failed block slid to the channel bed, revealing only the upper half of the failure plane, while on the sandy loam the failed block toppled forwards, exposing the failure plane for the complete bank height. This study has shown that it is possible to predict location, frequency and magnitude of the rill bank collapse, providing a basis for incorporation into predictive models for hillslope soil loss or rill network development. Copyright © 2006 John Wiley & Sons, Ltd. [source] Foreign direct investment and the dark side of decentralizationECONOMIC POLICY, Issue 49 2007Sebastian G. Kessing SUMMARY Fiscal decentralization VERTICAL, HORIZONTAL, AND FDI Both in the developed and developing world, decentralization of fiscal policy is frequently argued to foster investment, because allowing investors to choose between competing locations should make it difficult for each jurisdiction to tax the investment's returns. We point out that this ,horizontal' dimension of decentralization cannot eliminate ex post incentives to tax investments once they are irreversibly located in a jurisdiction, and that the negative ex ante investment effects of such ,hold up' problems are actually stronger when decentralization inevitably leads to multiple levels of taxation power in each location. Empirically, we detect significant negative effects on FDI of the ,vertical' dimension of decentralization, measured by the number of government layers, in a data set containing many countries and many suitable control variables. Indicators of overall fiscal decentralization do not appear to affect the investment climate negatively per se, but our theoretical arguments and empirical results suggest that policymakers should consider very carefully the form and degree of government decentralization if they aim at improving the investment climate. , Sebastian G. Kessing, Kai A. Konrad and Christos Kotsogiannis [source] Soil factors controlling the toxicity of copper and zinc to microbial processes in Australian soilsENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 4 2007Kris Broos Abstract Two soil microbial processes, substrate-induced nitrification (SIN) and substrate-induced respiration (SIR), were measured in the topsoils of 12 Australian field trials that were amended separately with increasing concentrations of ZnSO4 or CuSO4. The median effect concentration (EC50) values for Zn and Cu based on total metal concentrations varied between 107 and 8,298 mg kg,1 for Zn and 108 and 2,155 mg kg,1 Cu among soils. The differences in both Zn and Cu toxicity across the 12 soils were not explained by either the soil solution metal concentrations or CaCl2 -extractable metal concentrations, because the variation in the EC50 values was larger than those using total concentrations. Toxicity of Zn and Cu decreased with increasing soil pH for SIN. For Cu, also increasing cation exchange capacity (CEC) and percent clay decreased the toxicity towards SIN. In contrast to SIN, soil pH had no significant effect on toxicity values of SIR. Significant relationships were found between the EC50 values for SIR and background Zn and CEC for Zn, and percent clay and log CEC for Cu. Relationships such as those developed in this study will permit Australian environmental regulation to move from single-value national soil quality guidelines to soil-specific quality guidelines and permit soil-specific risk assessments to be undertaken. [source] A Geographic Information Systems,based, weights-of-evidence approach for diagnosing aquatic ecosystem impairmentENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 8 2006Katherine E. Kapo Abstract A Geographic Information Systems,based, watershed-level assessment using Bayesian weights of evidence (WOE) and weighted logistic regression (WLR) provides a method to determine and compare potential environmental stressors in lotic ecosystems and to create predictive models of general or species-specific biological impairment across numerous spatial scales based on limited existing sample data. The WOE/WLR technique used in the present study is a data-driven, probabilistic approach conceptualized in epidemiological research and both developed for and currently used in minerals exploration. Extrapolation of this methodology to a case-study watershed assessment of the Great and Little Miami watersheds (OH, USA) using archival data yielded baseline results consistent with previous assessments. The method additionally produced a quantitative determination of physical and chemical watershed stressor associations with biological impairment and a predicted comparative probability (i.e., favorability) of biological impairment at a spatial resolution of 0.5 km2 over the watershed study region. Habitat stressors showed the greatest spatial association with biological impairment in low-order streams (on average, 56% of total spatial association), whereas water chemistry, particularly that of wastewater effluent, was associated most strongly with biological impairment in high-order reaches (on average, 79% of total spatial association, 28% of which was attributed to effluent). Significant potential stressors varied by land-use and stream order as well as by species. This WOE/WLR method provides a highly useful "tier 1" watershed risk assessment product through the integration of various existing data sources, and it produces a clear visual communication of areas favorable for biological impairment and a quantitative ranking of candidate stressors and associated uncertainty. [source] Do Developing Countries Need a Development Box?EUROCHOICES, Issue 2 2003Jonathan Brooks Summary Do Developing Countries Need a Development Box? Developing country proposals for a Development Box focus on changes to WTO rules on agricultural trade that would enable them to address more effectively their objectives related to food security, poverty alleviation and economic development. Yet, there are few instances where developing countries have been constrained in the policies they can adopt. This does not mean that demands for a Development Box are pointless, for if the next WTO agreement is to have a real impact on rates of protection, there will be a need for tighter commitments in both developed and developing countries. Hence proposals for a Development Box can be seen as an insurance policy, given the prospect of deeper multilateral reforms. There is a strong case for easier access to safeguards, under which developing countries could temporarily apply higher tariffs on food security crops when world prices are depressed below threshold levels. There may be an economic justification for expanding the types of domestic support measures that developing countries can employ, in those rare cases where policies would otherwise be constrained. However, these demands should not constrain progress on the most important issue; namely, how OECD countries can do more for developing countries through improvements in market access, the elimination of explicit and implicit export subsidies, and reductions in trade-distorting domestic support. Faut-il une boite spéciale pour le développement ? Les propositions des pays en développement en vue ?établir une ,boîte pour le développement'à,OMC sont centrées sur ,idée qu'il convient de modifier les règies du commerce international agricole, afin de leur permettre ?aborder de façon plus efflcace leurs problèmes spécifiques de sécurité alimentaire, de réduction de la pauvreté et de développement économique. Pourtant, il existe peu ?exemples de situations dans lesquelles un pays en développement ait pu être gêné dans ,adoption ?une politique particulière. Cela ne veut pas dire qu'une boîte pour le développement soit inutile: si le prochain accord à,OMC doit avoir un effet réel sur les taux de protection, des engagements encore plus stricts seront nécessaires de la part, aussi bien des pays en développement que des pays développés. II en résulte que les propositions en vue ?une ,boîte pour le développement' peuvent être considérées comme une politique ?assurance, dans ,optique de réformes multilatérales plus approfondies. II y a des raisons sérieuses pour faciliter le recours aux clauses de sauvegarde, grâce auxquelles les pays en développement pourraient imposer temporairement des droits plus élevés sur les denrées importantes pour leur sécurité alimentaire lorsque les cours mondiaux descendent en deçà?un certain seuil. Il peut exister une justification économique à,extension des catégories de soutien que les pays en développement peuvent employer, dans les cas peu fréquents où les engagements pris seraient contraignants à cet égard. Mais surtout, il faut que les pays en développement prennent garde à ne pas entraver les progrès dans les domaines vraiment importants, à savoir ce que les pays de ,OCDE peuvent faire pour eux en améliorant ,accès aux marchés, en eliminant les subventions implicites et explicites aux exportations, et en réduisant les mesures de soutien intérieures qui affectent les échanges. Benötigen Entwicklungsländer eine Development Box? Die Vorschläge der Entwicklungsländer für eine Development Box zielen auf Änderungen in den Agrarhandelsvorschriften der WTO ab; es soil ihnen ermöglicht werden, ihre Zdele hinsichtlich der Nahrungsmt-telsicherheit, Armutsbekämpfung und Wirtschaftsentwicklung wirkungsvoller zu verfolgen. Bis heute jedoch wurden die Entwicklungsländer nur in wenigen Fällen bei der Ausgestaltung bestimmter Politikmaßnahmen eingeschränkt. Damit ist nicht gesagt, dass Forderungen nach einer Development Box zwecklos sind, denn wenn sich das kommende WTO-Abkommen tatsächlich auf die Protektionsraten auswirken soil, werden sowohl den entwickelten Ländern als auch den Entwicklungsländern mehr Verpflichtungen abverlangt werden. Daher können Vorschläge für eine Development Box als eine Versicherungspolirik vor dem Hintergrund der Aussicht auf tiefergreifende multilaterale Reformen angesehen werden. Es spricht vieles für einen einfacheren Zugang zu Schutzmaßnahmen, unter denen Entwicklungsländer vorübergehend höhere Zölle auf pflanzliche Erzeugnisse mit Bedeutung für die Nahrungsmittelsicherheit erheben könnten, wenn die Weltpreise unterhalb von Schwellenwerten liegen. Es mag aus ökonomischer Sicht eine Rechtfertigung für die Ausdehnung der inlandischen marktstützenden Maßnahmen geben, welche Entwicklungsländer anwenden dürfen; dies kann sinnvoll sein, wenn andernfalls, allerdings in seltenen Fällen, Politikmaßnahmen eingeschränkt werden müssten. Diese Forderungen sollten den Fortschritt bei den allerwichtigsten Themen jedoch nicht behindern; OECD-Länder können mehr für Entwicklungsländer tun, und zwar durch Verbesserung des Marktzugangs, durch die Abschaffung von expliziten und impliziten Exportsubventionen und durch Kürzungen bei den handelsverzerrenden Inlandssubventionen. [source] Report from the Rockefellar Foundation Sponsored International Workshop on reducing mortality and improving quality of life in long-term survivors of Hodgkin's disease: July 9,16, 2003, Bellagio, ItalyEUROPEAN JOURNAL OF HAEMATOLOGY, Issue 2005Peter Mauch Abstract:, A workshop, sponsored by the Rockefellar Foundation, was held between 9 to 16 July, 2003 to devise strategies to reduce mortality and improve quality of life of long-term survivors of Hodgkin's disease. Participants were selected for their clinical and research background on late effects after Hodgkin's disease therapy. Experts from both developed and developing nations were represented in the workshop, and efforts were made to ensure that the proposed strategies would be globally applicable whenever possible. The types of late complications, magnitude of the problem, contributing risk factors, methodology to assess the risk, and challenges faced by developing countries were presented. The main areas of late effects of Hodgkin's disease discussed were as follows: second malignancy, cardiac disease, infection, pulmonary dysfunction, endocrine abnormalities, and quality of life. This report summarizes the findings of the workshop, recommendations, and proposed research priorities in each of the above areas. [source] Tailoring Cell Behavior on Polymers by the Incorporation of Titanium Doped Phosphate Glass Filler,ADVANCED ENGINEERING MATERIALS, Issue 7 2010Wojciech Chrzanowski Abstract Understanding tissue response to materials, to enable modulation and guided tissue regeneration is one of the main challenges in biomaterials science. Nowadays polymers, glasses, and metals dominate as biomaterials. Often native properties of those materials are not sufficient and there is a need to combine them, so as to modify and adjust their properties to the application. The primary aim of this study was to improve cell response to polymer (PLDL) using phosphate glass as filler (titanium doped phosphate glass). As a control ,-tricalcium phosphate (TCP) filler was used. Various concentrations of the filler were used (10,40 vol%). Wetting behavior, , -potentials, mechanical and thermal properties, and human cells response to the materials were evaluated. Results showed that with increase in glass filler loading wettability improved, , -potentials dropped, and increase in stiffness of materials was observed. Importantly cell culture experiments showed more developed and well spread cells on the samples with glass content up to 20 vol%. Cells responded much more positively to the glass filled samples than to TCP filled. However, expression of osteocalcin and osteopontin, proteins that indicate formation of the mineralized structures was positive for all the samples including pure PLDL. It was concluded that due to improved wetting behavior, lower , -potentials, and specific chemistry of the glass filler it was possible to alter cells response, improve bioactivity of the polymer, and vary mechanical properties. [source] How Interface innovates with suppliers to create sustainability solutionsGLOBAL BUSINESS AND ORGANIZATIONAL EXCELLENCE, Issue 6 2009Eric Nelson Becoming a sustainable and restorative company can mean rethinking the basic components of your products. This leading carpet manufacturer's innovations, including those developed in collaboration with key suppliers, have changed the industry and moved the company closer to its sustainability goals. The author explains the company's seven areas of sustainability focus, and the role innovation plays in reducing its negative impact on the environment. He then describes Interface's approach for building supplier commitment and participation in these goals, and examines the firm's partnership with Universal Fibers, which led to the first commercially viable processes for incorporating postindustrial and postconsumer nylon in carpet facing and for salvaging old carpet from end-of-life disposal and recycling it into materials for new carpet production. © 2009 Wiley Periodicals, Inc. [source] Conservation laryngeal surgery versus total laryngectomy for radiation failure in laryngeal cancer,HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 9 2006F. Christopher Holsinger MD Abstract Background. Total laryngectomy is the standard of care for surgical salvage of radiation failure in laryngeal cancer. However, the role of conservation laryngeal surgery in this setting remains unclear. The objective was to compare the efficacy of conservation versus total laryngectomy for salvage of radiation failure in patients who initially presented with T1 or T2 squamous cancer of the larynx. Methods. A 21-year retrospective analysis of patients who received surgery at a single comprehensive cancer center after definitive radiation therapy is reported. At recurrence, the patients were reevaluated and then underwent a total laryngectomy or, if possible, a conservation laryngeal procedure. The charts of 105 patients who failed radiation treatment for primary laryngeal cancer and who subsequently underwent surgical salvage were reviewed for this study. Eighty-nine were male (84.8%). The mean age was 60.3 years. The median follow-up time after surgery was 69.4 months. Most patients with recurrence after radiotherapy required total laryngectomy (69.5%; 73/105). Conservation laryngeal surgery was performed for 32 patients (31.5%). Concomitant neck dissections were performed on 45 patients (45.5%). Results. In 14 patients, local or regional recurrence developed after salvage surgery: 9 patients after total laryngectomy (12.3%; 9/73), and 5 patients (15.6%; 5/32) after conservation laryngeal surgery. This difference was not statistically significant, nor was there a difference in disease-free interval for the two procedures (p = .634, by log-rank test). Distant metastasis developed in 13 patients. Most developed in the setting of local and/or regional recurrence, but distant metastasis occurred as the only site of failure in 6 of the patients who had undergone total laryngectomy but in 1 of the conservation surgery patients treated for a supraglottic laryngeal cancer. The overall mortality for patients who underwent total laryngectomy was also higher: 73.74% (54/73) versus 59.4% (19/32) for patients who underwent a conservation approach (p = .011 by log-rank test). Conclusions. Although conservation laryngeal surgery was possible in a few patients with local failure after radiotherapy, conservation laryngeal surgery is an oncologically sound alternative to total laryngectomy for these patients. © 2006 Wiley Periodicals, Inc. Head Neck, 2006 [source] Empirical implications of response acquiescence in discrete-choice contingent valuationHEALTH ECONOMICS, Issue 10 2006Raymond Y. T. Yeung Abstract The use of discrete-choice contingent valuation (CV) to elicit individuals' preference, expressed as maximum willingness-to-pay (WTP), although primarily developed in environmental economics, has been popular in the economic evaluation of health and healthcare. However, a concern with this method is the potential for ,over-estimating' WTP values due to the presence of response acquiescence, or ,yea-saying' bias. Based on a CV survey conducted to estimate physicians' valuation of clinic computerization, the extent of such bias was estimated from a within-sample open-ended valuation question following the respondents' discrete choice response. Analysis of this data suggests that not only was response acquiescence an issue, but also that the parametric estimation of mean and median WTP, the most common approach to estimating WTP from discrete-choice data, would potentially magnify such bias (to various degrees depending on the distributional assumptions applied). The possible extent of CV design versus analysis in discrete-choice methods therefore warrants further exploration. Copyright © 2006 John Wiley & Sons, Ltd. [source] Direct-to-consumer advertising of pharmaceuticals: developed countries experiences and TurkeyHEALTH EXPECTATIONS, Issue 1 2007Semih Semin MD PhD Abstract While several major problems concerning drugs occur in the world, the attempts to direct-to-consumer advertising (DTCA) has gained a considerable impetus lately in both developed and developing countries. DTCA has increasingly become an appealing advertising alternative for the pharmaceutical industry as drug companies have come to wrestle with such problems as the expansion of the drug market; the decline of the medical representatives' work efficiency; drug reimbursement restrictions; and the escalating role of the Internet in the consumer market. Some of the main disadvantages of the DTCA are: increasing drug expenditures, unnecessary drug consumption and adverse effect risks. Even though the influence of pharmaceuticals on health services and the economy hold the same importance in the developed and developing countries, its negative consequences have increased by encompassing developing countries in its grip. Therefore, in this review, using Turkey as an example, the situation of direct-to-consumer advertisements in developing countries is analysed in relation with developed countries. [source] The information trail of the ,Freshman 15',a systematic review of a health myth within the research and popular literatureHEALTH INFORMATION & LIBRARIES JOURNAL, Issue 1 2008Cecelia Brown Question: ,How does health misinformation become part of the American and Canadian vernacular? Data sources and selection: ,Twenty-three databases were searched for articles discussing university freshmen weight gain. Research articles were examined for methodology, number and gender of the participants and weight gain. Popular press articles were reviewed for the types of information published: expert/anecdotal, weight gain, nutrition, exercise, health and alcohol. A timeline of article publication dates was generated. Results: ,Twenty peer-reviewed, 19 magazine, 146 newspaper, and 141 university newspaper articles were discovered. Appearance of media articles about the ,Freshman 15' mirrored the peer-reviewed articles, yet the information did not reliably depict the research. Research indicated a weight gain of less than five pounds (2.268 kg), while half of the popular press publications claimed a 15-pound (6.804 kg) weight gain. The misinformation was frequently accompanied by information about achieving weight control through diet, exercise, stress reduction and alcohol avoidance. Conclusion: ,Understanding of how the concept of the ,Freshman 15' developed indicates that remediation efforts are needed. Collaborative efforts between health science and academic librarians, faculty and journalists to construct new paradigms for the translation of scientific evidence into information that individuals can use for decisions about health and well-being is suggested. [source] Sowing the Seeds of Progress: The Agricultural Biotechnology Debate in AfricaHISTORY COMPASS (ELECTRONIC), Issue 2 2008Noah Zerbe Recent innovations in agricultural biotechnology raise a number of questions for the future of farming in both the developed and developing worlds. Conflicting international agreements, particularly tensions between the World Trade Organization's Trade Related Intellectual Property Rights Agreement and the Convention on Biological Diversity, provoke debates between farmers, plant breeders, and indigenous communities over the extent of ownership rights in genetic resources. Further, trade disputes between the United States and the European Union help to shape the terrain on which biotechnology is developed. The future of agricultural biotechnology in Africa is largely a function of the outcome of these debates. [source] Working for the familyHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 2 2007Sandy MacDonald Recent writing about the ,service encounter' suggests that high-quality service requires employee commitment and this will involve a more developed and sophisticated approach to HRM than has traditionally characterised the sector. Through an in-depth study of a sample of high service level hotels in the US and UK this paper argues, in contrast, that commitment can be created through a workplace culture that draws on family discourses and practices. It explores the ways in which this culture is developed and endorsed by both management and employees. This approach to generating commitment has costs in terms of the time and priority employees can give to their ,real' friends and family. By drawing on the highly gendered and hierarchical organisation of the family, it is argued that culture also contributes to gender stereotyping and hierarchies within and outside the workplace in ways that limit women's career opportunities. [source] The Limits of Women's Quotas in BrazilIDS BULLETIN, Issue 5 2010Clara Araújo In this article, I examine the case of Brazil which, unlike many other Latin American countries, is an example of where quotas are not working. Drawing on over ten years of research and exploring the dynamics of a varied group of political parties, I contest that male resistance is not the only reason behind this failure. Vagueness around the quota law and a lack of sanctions, together with the elitist nature of politics in Brazil are all contributing factors. My research has also revealed a few anomalies, showing that contrary to much of the literature, women would seem to fare better in elections within less developed and smaller states in Brazil. In conclusion, I propose that in order to move forward and get quotas, working reform measures are needed to strengthen the law, but in addition, women's access to financial support for campaigning needs to be fully understood. [source] Primitive immune systems: Are your ways my ways?IMMUNOLOGICAL REVIEWS, Issue 1 2004Baruch Rinkevich Summary:, Although vertebrate immune systems have been commonly conceived as exquisitely developed to combat pervasiveness by pathogens, they are not infallible. The enigmatic expression of histocompatibility in vertebrates, the manifestation of natural chimerism, autoimmunity, malignancy, and other puzzling outcomes hint that immunity did not arise in evolution to fight infections and that this capacity is a late evolutionary appendage, owing its appearance to the redeployment of a system developed for other reasons. Allorecognition in the colonial tunicate Botryllus schlosseri serves here as a platform for a contending paradigm, advocating that immunity has developed as a surveillance machinery against and for purging of nascent selfish cells (stemmed from a kin organism or from transformed cells within the organism of origin). Defense against pathogens (always representing xenogeneic aliens) appeared later, revealing the multiplicity of newly developed phenomena. Allorecognition events characteristic of the Botryllus primitive immune system, such as fusion versus rejection, the morphological resorption with its expressed hierarchy, and the somatic/germ-cell parasitic outcomes, provide clues to the evolutionary basis of allorecognition. Recent work on Botryllus immunity that highlights the cost of littering individuality by somatic variants/allogeneic cells is discussed. [source] Using economic instruments to overcome obstacles to in situ conservation of biodiversityINTEGRATIVE ZOOLOGY (ELECTRONIC), Issue 1 2006Jeffrey A. McNEELY Abstract The leading direct cause of the loss of biodiversity is habitat alteration and disruption. If we are to address this cause directly, we need to find ways of changing the behavior of rural people. Experience has shown that this is done most effectively through the use of economic instruments, ranging from taxes that discourage over-exploitation, to direct payments for conservation activities carried out by rural land-owners or those occupying the land. In many parts of the world, governments provide incentives such as tax breaks to private land-owners. Other countries recognize specific use rights on particular parts of the land, enabling the land-owners to earn appropriate benefits. Since many protected areas have resident human populations, it is especially important that they be encouraged to contribute to the objectives of the protected area, and economic incentives offer an important way of doing so; they might, for example, be given employment in the protected area or in associated tourism activities. Direct payments to farmers for conserving watersheds is becoming increasingly popular, in both developed and developing countries. Improved conservation will require both removing perverse subsidies and developing a wide range of approaches for rewarding land-owners for biodiversity conservation activities. [source] Three-dimensional finite element analyses of passive pile behaviourINTERNATIONAL JOURNAL FOR NUMERICAL AND ANALYTICAL METHODS IN GEOMECHANICS, Issue 7 2006L. F. Miao Abstract Piles may be subjected to lateral soil pressures as a result of lateral soil movements from nearby construction-related activities such as embankment construction or excavation operations. Three-dimensional finite element analyses have been carried out to investigate the response of a single pile when subjected to lateral soil movements. The pile and the soil were modelled using 20-node quadrilateral brick elements with reduced integration. For compatibility between the soil,pile interface elements, 27-node quadrilateral brick elements with reduced integration were used to model the soil around the pile adjacent to the soil,pile interface. A Mohr,Coulomb elastic,plastic constitutive model with large-strain mode was assumed for the soil. The analyses indicate that the behaviour of the pile was significantly influenced by the pile flexibility, the magnitude of soil movement, the pile head boundary conditions, the shape of the soil movement profile and the thickness of the moving soil mass. Reasonable agreement is found between some existing published solutions and those developed herein. Copyright © 2005 John Wiley & Sons, Ltd. [source] A monolithic approach for interaction of incompressible viscous fluid and an elastic body based on fluid pressure Poisson equationINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING, Issue 2 2005Daisuke Ishihara Abstract This paper describes a new monolithic approach based on the fluid pressure Poisson equation (PPE) to solve an interaction problem of incompressible viscous fluid and an elastic body. The PPE is derived so as to be consistent with the coupled equation system for the fluid-structure interaction (FSI). Based on this approach, we develop two kinds of efficient monolithic methods. In both methods, the fluid pressure is derived implicitly so as to satisfy the incompressibility constraint, and all other unknown variables are derived fully explicitly or partially explicitly. The coefficient matrix of the PPE for the FSI becomes symmetric and positive definite and its condition is insensitive to inhomogeneity of material properties. The arbitrary Lagrangian,Eulerian (ALE) method is employed for the fluid part in order to take into account the deformable fluid-structure interface. To demonstrate fundamental performances of the proposed approach, the developed two monolithic methods are applied to evaluate the added mass and the added damping of a circular cylinder as well as to simulate the vibration of a rectangular cylinder induced by vortex shedding. Copyright © 2005 John Wiley & Sons, Ltd. [source] Perioperative heart failure in coronary surgery and timing of intra-aortic balloon pump insertionACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 7 2010M. RANUCCI Background: Perioperative heart failure (HF) in coronary operations is accompanied by a high operative mortality rate. An intra-aortic balloon pump (IABP) is often used to treat this syndrome. The correct timing for IABP insertion after completion of the operation has not yet been investigated. The aim of this study was to investigate the operative mortality in perioperative HF patients who had undergone coronary operations with respect to the early or the late use of IABP. Methods: This is a retrospective study including 7,270 patients who had undergone coronary surgery with or without associated procedures. A population of patients with perioperative HF was extracted and analyzed with respect to the use of drugs, intra-operative or post-operative IABP to treat this condition. Results: A total of 1,051 (14.5%) patients had perioperative HF. The mortality rate in this group was 13.5%. Early (intra-operative) IABP insertion was performed in 123 patients. In contrast, 928 patients were treated with inotropic drugs only, and, of these patients, 59 developed a drug-refractory HF requiring late IABP insertion. Operative mortality was significantly (P=0.001) higher in patients requiring late (64.4%) vs. early (41.5%) IABP insertion. Independent risk factors for developing a drug-refractory HF were age, pre-operative serum creatinine value and an associated mitral valve procedure. Conclusions: Postponing the use of IABP may be deleterious in patients with drug-refractory HF. In the presence of the three factors independently associated with the risk of a drug-refractory HF, early IABP insertion is suggested. [source] Performance optimization of object comparisonINTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS, Issue 10 2009Axel Hallez Comparing objects can be considered as a hierarchical process. Separate aspects of objects are compared to each other, and the results of these comparisons are combined into a single result in one or more steps by aggregation operators. The set of operators used to compare the objects and the way these operators are related with each other is called the comparison scheme. If a threshold is applied to the final result of the object comparison, the mathematical properties of the operators in the comparison scheme can be used to derive thresholds on the intermediate results. These derived threshold can be used to break of a comparison early, thus offering a reduction of the comparison cost. Using this information, we show that the order in which the operators are evaluated has an influence on the average cost of comparing two objects. Next, we proceed with a study of the properties that allow us to find an optimal order, such that this average cost is minimized. Finally, we provide an algorithm that calculates an optimal order efficiently. Although specifically developed for object comparison, the algorithm can be applied to all kinds of selection processes that involve the combination of several test results. © 2009 Wiley Periodicals, Inc. [source] | ||||||||||||||||||||||||||||||||||||||||||||||