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Deep Periodontal Pockets (deep + periodontal_pocket)
Selected AbstractsGingival crevicular fluid laminin-5 ,2-chain levels in periodontal diseaseJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 7 2006Gülnur Emingil Abstract Aim: Our study aimed to examine the molecular forms and gingival crevicular fluid (GCF) levels of laminin-5 ,2-chain in patients with different periodontal disease, and compare the effects of P.gingivalis trypsin-like proteinase on intact laminin-5 ,2-chain species. Methods: Eighteen patients with generalized aggressive periodontitis (G-AgP), 29 patients with chronic periodontitis (CP), 20 with gingivitis and 20 periodontally healthy subjects were included. Probing depth, clinical attachment loss, presence of bleeding on probing and plaque were recorded. Molecular forms and GCF laminin-5 ,2-chain levels and the effects of P. gingivalis trypsin-like proteinase on intact laminin-5 ,2-chain were analysed by computer-quantitated Western immunoblotting. Results: Laminin-5 ,2-chain 40 and 70 kDa fragments could be detected in all groups, in varying levels. The CP group had elevated GCF laminin-5 ,2-chain fragment levels compared with the gingivitis and healthy groups (p<0.008). The G-AgP group had GCF laminin-5 ,2-chain fragment levels similar to the gingivitis and healthy groups (p>0.008). GCF laminin-5 ,2-chain fragments differed clearly from the multiple lower molecular size fragments of P.gingivalis trypsin-laminin-5 ,2-chain proteinases. Conclusion: Increased GCF laminin-5 ,2-chain fragments in periodontitis sites with deep periodontal pocket suggest that these cleaved 40 and 70 kDa fragments could reflect the extent of the inflammatory reaction in CP. [source] Oral hygiene practices, periodontal conditions, dentition status and self-reported bad mouth breath among young mothers, TanzaniaINTERNATIONAL JOURNAL OF DENTAL HYGIENE, Issue 4 2006EGS Mumghamba Abstract:,Objectives:,To determine the oral hygiene practices, periodontal conditions, dentition status and self-reported bad mouth breath (S-BMB) among young mothers. Study participants and methods:,This was a cross-sectional descriptive study conducted at Muhimbili National Hospital, Dar es Salaam, Tanzania. A total of 302 postpartum mothers, aged 14,44 years, were interviewed on oral hygiene practices and S-BMB using structured questionnaire. Oral hygiene, dentition and periodontal status were assessed using the Community Periodontal Index probe and gingival recessions (GR) using Williams Periodontal probe. Results:,Tooth brushing practice was 99%; tongue brushing (95%), plastic toothbrush users (96%), chewing stick (1%), wooden toothpicks (76%), dental floss (<1%); and toothpaste (93%). The prevalence of plaque and gingival bleeding on probing was 100%, gum bleeding during tooth brushing (33%), calculus (99%), probing periodontal pocket depth (PPD) 4,5 mm (27%), PPD 6+ mm (3%), GR 1+ mm (27%) and tooth decay (55%). The prevalence of S-BMB was 14%; the S-BMB had higher mean number of sites with plaque compared to the no S-BMB group (P = 0.04). Factors associated with S-BMB were gum bleeding on tooth brushing (OR = 2.4) and PPD 6+ mm (OR = 5.4). Conclusion:,Self-reported bad mouth breath is a cause of concern among young mothers, and associated significant factors were gum bleeding on tooth brushing and deep periodontal pockets of 6+ mm. Further research involving clinical diagnosis of bad mouth breath and intervention through oral health promotion and periodontal therapy are recommended. Clinical relevance:,This study provides baseline information on oral health status and the complaint on bad mouth breath which necessitates in the future need for objective assessment, diagnosis and management of bad mouth breath for enhanced social and professional interaction without embarrassments. [source] Microbial colonization patterns predict the outcomes of surgical treatment of intrabony defectsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 1 2006Lisa Heitz-Mayfield Abstract Aim: To explore the impact of bacterial load and microbial colonization patterns on the clinical outcomes of periodontal surgery at deep intrabony defects. Materials and Methods: One hundred and twenty-two patients with advanced chronic periodontitis and at least one intrabony defect of >3 mm were recruited in 10 centres. Before recruitment, the infection control phase of periodontal therapy was completed. After surgical access and debridement, the regenerative material was applied in the test subjects, and omitted in the controls. At baseline and 1 year following the interventions, clinical attachment levels (CAL), pocket probing depths (PPD), recession (REC), full-mouth plaque scores and full-mouth bleeding scores were assessed. Microbial colonization of the defect-associated pocket was assessed using a DNA,DNA checkerboard analysis. Results: Total bacterial load and counts of red complex bacteria were negatively associated with CAL gains 1 year following treatment. The probability of achieving above median CAL gains (>3 mm) was significantly decreased by higher total bacterial counts, higher red complex and T. forsythensis counts immediately before surgery. Conclusions: Presence of high bacterial load and specific periodontal pathogen complexes in deep periodontal pockets associated with intrabony defects had a significant negative impact on the 1 year outcome of surgical/regenerative treatment. [source] Systemic disorders in patients with periodontal diseaseJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 4 2003Maria Lagervall Abstract Background, aims: Over the past 10 years several studies have been published pointing towards a relationship between periodontal disease and various systemic disorders or diseases. The purpose of this retrospective study was to investigate the occurrence of self-reported systemic disorders in patients referred to a specialist clinic for periodontal treatment and to explore possible relationships between general health and periodontal disease severity in this population. Material and Methods: Data were collected from the dental records and the health questionnaires of 1006 subjects. Stepwise multiple linear regression analyses were adopted to calculate correlations between systemic disorders as independent variables and number of remaining teeth and the relative frequency of periodontal pockets of 5 mm or more, respectively, as the dependent variable. Results: The number of remaining teeth was significantly and positively correlated to the presence of cardiovascular disease, diabetes and rheumatoid disease after adjustment for age, sex and smoking. The relative frequency of diseased sites, however, was not significantly correlated to any one of the investigated systemic health disorders. Conclusion: No significant associations between investigated systemic disorders and periodontal disease severity were found if the relative frequency of deep periodontal pockets was used as the clinical parameter for periodontal disease severity. However, cardiovascular disease, diabetes and rheumatoid disease were found to be significantly correlated to number of lost teeth, which may represent one aspect of periodontal health. This result held true in nonsmokers only. Zusammenfassung Hintergrund: Während der letzten 10 Jahre wurden zahlreiche Studien publiziert, die auf einen Zusammenhang zwischen Parodontitis und verschiedenen systemischen Störungen und Erkrankungen hinweisen. Zielsetzung: Feststellung der Häufigkeit von selbst angegebenen systemischen Erkrankungen bei Patienten, die an eine parodontologische Spezialklinik zur Parodontitistherapie überwiesen worden waren, in einer retrospektiven Studie und Untersuchung möglicher Zusammenhänge zwischen allgemeiner Gesundheit und dem Schweregrad parodontaler Erkrankungen in dieser Bevölkerungsgruppe. Material und Methoden: Die Daten wurden aus den Behandlungsakten und Gesundheitsfragebögen von 1006 Personen gewonnen. Eine schrittweise multiple lineare Regressionsanalyse wurde verwendet, um Korrelationen zwischen systemischen Erkrankungen als unabhängigen Variablen und der Zahl verbliebener Zähne bzw. der relativen Häufigkeit parodontaler Taschen 5 mm als abhängigen Variablen zu berechnen. Ergebnisse: Nach Korrektur für Alter, Geschlecht und Rauchen war die Zahl verbliebener Zähne signifikant positiv mit Herz-Kreislauf-Erkrankungen, Diabetes und rheumatischen Erkrankungen korreliert. Die relative Häufigkeit erkrankter Stellen war allerdings mit keiner der untersuchten systemischen Erkrankungen korreliert. Schlussfolgerung: Wenn die relative Häufigkeit tiefer parodontaler Taschen als Maß für den Schweregrad parodontaler Erkrankung gewählt wurde, ließ sich keine Assoziation zwischen den untersuchten systemischen Erkrankungen und dem Parodontitisschweregrad zeigen. Allerdings waren Herz-Kreislauf-Erkrankungen, Diabetes und rheumatischen Erkrankungen signifikant mit der Zahl verlorener Zähne korreliert, die einen Aspekt parodontaler Gesundheit repräsentieren. Dieses Ergebnis ergab sich aber nur für Nichtraucher. Résumé Références et buts: Au cours des 10 dernières années, plusieurs études ont été publiées pour souligner une relation entre la maladie parodontale et diverses désordres ou maladies systémiques. Cette étude rétrospective se propose de rechercher l'apparition de désordres systémiques racontés par des patients adressés à une clinique spécialisée pour traitement parodontal et d'explorer de possibles relations entre la santé générale et la sévérité de la maladie parodontale dans cette population. Matériel et Méthodes: Les données furent récoltées des dossiers dentaires et des interrogatoires médicaux de 1006 sujets. Une analyse de régression multiple linéaire échelonnée a été utilisée pour calculer les corrélations entre les désordres systémiques en tant que variables indépendantes et le nombre de dents restantes et la fréquence relative de poches parodontales d'au moins 5mm, respectivement, comme variable dépendante. Résultats: le nombre de dents restantes était significativement et positivement corréléà la présence de maladies cardiovasculaires, de diabète et de maladie rhumatoïde après ajustement pour l'âge, le sexe, et le tabagisme. La relative fréquence de sites malades, cependant, n'était corrélée à aucun des désordres systémiques étudiés. Conclusion: Aucune association significative entre les désordres systémiques étudiés et la sévérité de la maladie parodontale ne fut trouvée lorsque la fréquence relative de poches parodontales profondes était utilisée comme paramètre clinique pour définir la sévérité de la maladie parodontale. Cependant, une maladie cardio-vasculaire, le diabète, une maladie rhumatoïde sont corrélées significativement au nombre de dents perdues qui peut être représentatif d'un aspect de santé parodontale. Ces résultats n'étaient valables que chez les non fumeurs. [source] Herpesviruses in periodontal pocket and gingival tissue specimensMOLECULAR ORAL MICROBIOLOGY, Issue 1 2000A. Contreras Human cytomegalovirus (HCMV) and Epstein-Barr virus type 1 (EBV-1) are frequently detected in crevicular fluid of deep periodontal pockets, but little or no information is available on occurence of herpesviruses in gingival tissue. This investigation studied the presence of herpesviruses in periodontal pockets and the corresponding gingival tissues from 11 periodontally healthy and 14 periodontitis sites. A nested-polymerase chain reaction was employed to identify the presence of HCMV, EBV-1, EBV-2, herpes simplex virus, human herpesvirus (HHV)-6, HHV-7 and HHV-8 in each test sample. In healthy periodontal sites, HCMV was detected in 1 (9%) and EBV-1 in 2 (18%) pocket samples, and HCMV was detected in 2 (18%) and EBV-1 in 3 (27%) gingival tissue samples. In periodontitis lesions, HCMV was detected in 9 (64%) pocket samples and in 12 (86%) gingival tissue samples, and EBV-1 was detected in 6 (43%) pocket samples and in 11 (79%) gingival tissue samples. HHV-6 and HHV-8 were detected exclusively in gingival tissue samples. The present findings confirm the frequent presence of HCMV and EBV-1 in periodontitis lesions and suggest using gingival tissue specimens for detecting periodontal HHV-6, HHV-7 and HHV-8. [source] | ||||||||||