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Addition Reactions (addition + reaction)
Kinds of Addition Reactions Selected AbstractsA New Autocatalytic Thioacetate-Enal Addition Reaction: A Michael Addition or Not?ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2010Gennadiy Ilyashenko Abstract Rather than proceeding through a Michael-type or 1,4-addition, thioacetic acid adds across unsaturated aldehydes in an autocatalytic manner and involving a double exotherm, as demonstrated by both adiabatic and reaction calorimetry. NMR studies show that an intermediate acylthio-hemiacetal is involved and that the product continues to react competitively with thioacetic acid. [source] Asymmetric Michael Addition Reaction of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Alkyl- Substituted Thiourea CatalystADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 2-3 2010Xin Li Abstract A simple alkylthiourea was found to be an effective catalyst for the Michael addition reaction of 3-substituted oxindole to nitroolefins. A number of 3,3,-substituted oxindole derivatives, which have two vicinal quaternary-tertiary chiral centers were synthesized with up to 99% yield, 19:1 dr and 98% ee. [source] Synthesis of 2,5-Diaminoquinones by One-Pot Copper-Catalyzed Aerobic Oxidation of Hydroquinones and Addition Reaction of AminesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2009Sungjin Kim Abstract The aerobic oxidation of various hydroquinones was achieved by using copper nanoparticles entrapped in aluminum oxyhydroxide [Cu/AlO(OH)] at room temperature. Furthermore, 2,5-diamino-1,4-benzoquinones were synthesized directly from hydroquinone and amines by a one-pot procedure consisting of the copper-catalyzed aerobic oxidation of hydroquinones and the double addition of amines to the resulting quinones. [source] Ferric Chloride Hexahydrate-Catalyzed Highly Regio- and Stereoselective Conjugate Addition Reaction of 2,3-Allenoates with Grignard Reagents: An Efficient Synthesis of ,,,-AlkenoatesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Guobi Chai Abstract Ferric chloride hexahydrate was shown to be an efficient catalyst for the conjugate addition of 2,3-allenoates with alkyl-, aryl-, or vinyl-Grignard reagents to synthesize polysubstituted ,,,-unsaturated alkenoates with high regio- and stereoselectivity. The in situ formed magnesium dienolate may readily react with different electrophilic reagents under different reaction conditions with or without a catalyst to construct an allylic quaternary carbon at the ,-position of the ester group and a stereocontrollable retention of the carbon-carbon double bond. [source] Pronounced Catalytic Effect of a Micellar Solution of Sodium Dodecyl Sulfate (SDS) on the Efficient C-S Bond Formation via an Odorless Thia-Michael Addition Reaction through the in situ Generation of S -Alkylisothiouronium SaltsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 5 2009Habib Firouzabadi Abstract A pronounced catalytic effect of sodium dodecyl sulfate (SDS) was observed on the in situ production of S -alkylisothiouronium salts via the reaction of primary, allyl and benzyl halides with thiourea in SDS droplets .Hydrolysis of the generated S -alkylisothiouronium salts in the palisade layer of the droplets produces the corresponding thiol moieties which are immediately added to the electron-deficient olefins that are present in the micellar core to produce the thia-Michael adducts. The entire route is an almost odorless process. The yields of the products are good to excellent and the method is applicable to large-scale operation without any problem. [source] ChemInform Abstract: Asymmetric Michael Addition Reaction of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Alkyl-Substituted Thiourea Catalyst.CHEMINFORM, Issue 26 2010Xin Li Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Efficient Michael Addition Reaction of Amines Catalyzed by Silica-Supported Aluminum Chloride.CHEMINFORM, Issue 33 2009Mohammad R. Saidi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient ZrCl4 Catalyzed Aza-Michael Addition Reaction: Synthesis of C-Linked Carbo ,3 -Amino Acids.CHEMINFORM, Issue 31 2009Krishna Damera Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: N-Donor Ligand as Catalyst: A Simple Aza-Michael Addition Reaction in Aqueous Media.CHEMINFORM, Issue 15 2009Shivaji S. Pawar Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Catalytic Nucleophilic Addition Reaction to (2-Furyl)carbene Intermediates Generated from Carbonyl,Ene,Ynes.CHEMINFORM, Issue 3 2009Koji Miki Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Ni-Catalyzed Addition Reaction of Allylic Selenides to Alkynes.CHEMINFORM, Issue 2 2008Koh-ichiro Yamashita Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Efficient Addition Reaction of Bromonitromethane to Aldehydes Catalyzed by NaI: A New Route to 1-Bromo-1-nitroalkan-2-ols under Very Mild Conditions.CHEMINFORM, Issue 15 2007Jose M. Concellon Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Sequential Addition Reaction of Lithium Acetylides and Grignard Reagents to Thioiminium Salts from Thiolactams Leading to 2,2-Disubstituted Cyclic Amines.CHEMINFORM, Issue 41 2006Toshiaki Murai Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Broensted Acid Mediated Heterogeneous Addition Reaction of 1,3-Dicarbonyl Compounds to Alkenes and Alcohols.CHEMINFORM, Issue 33 2006Ken Motokura Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of Some 2-Aminonitroethanes via Tin(II)chloride Mediated Addition Reaction of Bromonitromethane to Imines.CHEMINFORM, Issue 48 2005Ali S. Mahasneh No abstract is available for this article. [source] Homolytic Addition Reaction of Vinylsulfonylfluorobenzene.CHEMINFORM, Issue 41 2002S. V. Amosova Abstract For Abstract see ChemInform Abstract in Full Text. [source] Dramatic Improvement of the Enantiomeric Excess in the Asymmetric Conjugate Addition Reaction Using New Experimental Conditions.CHEMINFORM, Issue 38 2002A. Alexakis Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Cp2TiCl2(cat.)/Zn System Promoted Addition Reaction of Bromodifluoroacetate with the Electron-Deficient gem-Dicyanoalkenes.CHEMINFORM, Issue 6 2002Gang Zhao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Conjugated Addition Reaction of Amine, Carbon Disulfide to Electrophilic Alkenes in the Presence of Anhydrous Potassium Phosphate.CHEMINFORM, Issue 51 2001Baoguo Guo Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Chiral C2 -Symmetric 2,3-Disubstituted Aziridine and 2,6-Disubstituted Piperidine as Chiral Ligands in the Addition Reaction of Diethylzinc with Arylaldehydes.CHEMINFORM, Issue 25 2001Min Shi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Copper-Catalyzed Amine,Alkyne,Alkyne Addition Reaction: An Efficient Method For the Synthesis of ,,,-Alkynyl-,-amino Acid DerivativesCHEMISTRY - A EUROPEAN JOURNAL, Issue 43 2009Lei Zhou Abstract A simple and efficient method for the synthesis of ,,,-alkynyl-,-amino acid derivatives by a copper-catalyzed three-component amine,alkyne,alkyne addition reaction was developed. Various ,,,-alkynyl-,-amino acid derivatives were synthesized in moderate to good yields in one step. With chiral prolinol derivatives employed as the amine component, excellent diastereoselectivities (up to >99:1 diastereomeric ratio (dr)) were obtained. The scope of the reaction and further transformations of the resulting amino acid derivatives, such as deprotection and cyclization are also described. [source] Addition Reactions of Sulfenyl and Sulfinyl Chlorides with 3-Phenyl-1-azabicyclo[1.1.0]butaneHELVETICA CHIMICA ACTA, Issue 8 2008Grzegorz Mlosto Abstract The reactions of 3-phenyl-1-azabicyclo[1.1.0]butane with , -chlorosulfenyl chlorides and sulfinyl chlorides lead to the corresponding sulfenamides and sulfinamides, respectively, which possess an azetidine ring. It is proposed that a two-step mechanism occurs involving an intermediate carbenium ion, which is formed by the addition of the electrophile at the N-atom and cleavage of the N(1)C(3) bond. The structures of 9b and 10b are established by X-ray crystallography. [source] Highly Enantioselective Michael Addition Reactions of 3-Substituted Benzofuran-2(3H)-ones to Chalcones Catalyzed by a Chiral Alkyl-Substituted ThioureaADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7 2010Xin Li Abstract A highly enantioselective Michael addition of 3-substituted benzofuran-2(3H)-ones to chalcones catalyzed by a chiral bifunctional thiourea was developed. Several chiral 3,3,-substituted benzofuran-2(3H)-ones derivatives, bearing adjacent quaternary-tertiary stereocenters, were efficiently synthesized with excellent enantioselectivities. [source] The Use of Samarium Enolates, A Novel Alternative in the Addition Reactions to Imines.ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 20094-Diamino Esters, Amides, Enantiopure , Synthesis of 3-Amino Esters Abstract An efficient reaction of tosylimines with a range of samarium enolates (derived from esters, and amides) is reported. The reaction with the ,-dibenzylamino- N - tert- butanesulfinimine derived from chiral phenylalaninal afforded the corresponding enantiopure 3,4-diamino ester with very high diastereoselectivity. [source] Regioselective Addition Reactions of Propargyl Bromides to Carbonyl Compounds with Gallium Catalyzed by IndiumADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2005Ho Lee Abstract Reactions of organogallium reagents generated from propargyl bromides having substituents at the ,-position and gallium in the presence of 5,mol,% of indium with aldehydes and ketones selectively produced homoallenyl alcohols in good to excellent yields. Treatment of organogallium reagents obtained from propargyl bromide or propargyl bromides having substituents at the ,-position and gallium in the presence of 5,mol,% of indium with carbonyl compounds selectively afforded homopropargyl alcohols. [source] Gold(III) Chloride-Catalyzed Addition Reactions of Electron-Rich Arenes to Methyl Vinyl KetoneADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11 2003Gerald Dyker Abstract For the reaction of ,,,-unsaturated ketones with electron-rich arenes catalyzed by gold(III) chloride both, a Friedel,Crafts-type mechanism and an initial metallation, are evaluated. Gold(III) chloride has proven to be an efficient catalyst under very moderate reaction conditions, however, in the case of sterically demanding products HBF4 turned out to be the superior catalyst. [source] Innentitelbild: Addition Reactions of Sulfonylimidates with Imines Catalyzed by Alkaline Earth Metals (Angew. Chem.ANGEWANDTE CHEMIE, Issue 32 200932/2009) Additionsreaktionen zwischen Sulfonylimidaten und Iminen werden durch Erdalkalimetallalkoxide, die reichlich verfügbar, billig und nichttoxisch sind, katalysiert, wie S. Kobayashi et,al. in der Zuschrift auf S.,6041,ff. schildern. Die Diastereoselektivität wird durch Solvens und Katalysator beeinflusst: In DMF ist die Reaktion unabhängig davon, ob 1,8-Diazabicyclo[5.4.0]undec-7-en oder ein Metallalkoxid der Katalysator ist, anti-selektiv. In THF werden mit einem Metallalkoxid syn -Produkte erhalten. [source] Addition Reactions of Sulfonylimidates with Imines Catalyzed by Alkaline Earth Metals,ANGEWANDTE CHEMIE, Issue 32 2009Huy Van, Nguyen Dr. Billig und sicher: Additionen von Sulfonylimidaten an Imine können durch billige und ungiftige Alkoxide der Erdalkalimetalle katalysiert werden. Die Diastereoselektivität hängt stark vom Lösungsmittel und vom Katalysator ab; sowohl die syn - als auch die anti -Addukte sind diastereoselektiv in hohen Ausbeuten zugänglich (siehe Schema). Darüber hinaus wird die erste katalytische asymmetrische Mannich-Reaktion eines Sulfonylimidats präsentiert. [source] ChemInform Abstract: Efficient Direct Asymmetric Vinylogous Michael Addition Reactions of ,-Butenolides to Chalcones Catalyzed by Vicinal Primary-Diamine Salts.CHEMINFORM, Issue 30 2010Junfeng Wang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: One-Pot, Solvent-Free Regioselective Addition Reactions of Propargyl Bromide to Carbonyl Compounds Mediated by Zn,Cu Couple.CHEMINFORM, Issue 13 2010Xiaofang Ma Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. 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