Cysts

Distribution by Scientific Domains
Distribution within Medical Sciences

Kinds of Cysts

  • aneurysmal bone cyst
  • arachnoid cyst
  • benign cyst
  • benign lymphoepithelial cyst
  • bone cyst
  • branchial cleft cyst
  • bronchogenic cyst
  • calcifying odontogenic cyst
  • choroid plexus cyst
  • cleft cyst
  • cysticercu cyst
  • dentigerou cyst
  • dermoid cyst
  • duct cyst
  • duplication cyst
  • epidermal cyst
  • epidermal inclusion cyst
  • epidermoid cyst
  • epithelial cyst
  • follicular cyst
  • hepatic cyst
  • hydatid cyst
  • inclusion cyst
  • liver cyst
  • lymphoepithelial cyst
  • maxillary cyst
  • multiple cyst
  • odontogenic cyst
  • orbital cyst
  • ovarian cyst
  • pancreatic cyst
  • parathyroid cyst
  • plexus cyst
  • postoperative maxillary cyst
  • radicular cyst
  • rathke cleft cyst
  • renal cyst
  • resting cyst
  • seminal vesicle cyst
  • simple cyst
  • thymic cyst
  • thyroglossal duct cyst
  • thyroid cyst
  • urachal cyst
  • vesicle cyst

  • Terms modified by Cysts

  • cyst fluid
  • cyst formation
  • cyst morphology
  • cyst nematode
  • cyst nematodes
  • cyst production
  • cyst wall

  • Selected Abstracts


    CYST,THECA RELATIONSHIP, LIFE CYCLE, AND EFFECTS OF TEMPERATURE AND SALINITY ON THE CYST MORPHOLOGY OF GONYAULAX BALTICA SP.

    JOURNAL OF PHYCOLOGY, Issue 4 2002
    NOV. (DINOPHYCEAE) FROM THE BALTIC SEA AREA
    A new species of Gonyaulax, here named Gonyaulax baltica sp. nov., has been isolated from sediment samples from the southeastern Baltic. Culture strains were established from individually isolated cysts, and cyst formation was induced in a nitrogen-depleted medium. Although G. baltica cysts are similar to some forms attributed to Spiniferites bulloideus and the motile stage of G. baltica has affinities with G. spinifera, the combination of features of cyst and motile stage of G. baltica is unique. The culture strains were able to grow at salinity levels from 5 to 55 psu and formed cysts from 10 to 50 psu. Cultures at each salinity level were grown at 12, 16, and 20° C. Temperature- and salinity-controlled morphological variability was found in the resting cysts. Central body size varied with temperature and salinity, and process length varied with salinity. Cysts that formed at extreme salinity levels displayed lower average process length than cysts formed at intermediate salinity levels, and central body length and width were lowest at higher temperature and lower salinity. Models for the relationship between central body size and temperature/salinity and process length and salinity have been developed and may be used to determine relative paleosalinity and paleotemperature levels. Our results on salinity-dependent process length confirm earlier reports on short-spined cysts of this species found in low salinity environments, and the model makes it possible to attempt to quantify past salinity levels. [source]


    EXTRAGENITAL MULLERIAN ADENOSARCOMA WITH SARCOMATOUS OVERGROWTH ARISING IN AN ENDOMETRIOTIC CYST IN THE POUCH OF DOUGLAS

    PATHOLOGY INTERNATIONAL, Issue 12 2001
    Murugasu A
    No abstract is available for this article. [source]


    RETRORECTAL DERMOID CYST IN AN ADULT

    ANZ JOURNAL OF SURGERY, Issue 5 2008
    Deborshi Sharma MS
    No abstract is available for this article. [source]


    INJECTABLE FORM OF CALCIUM SULPHATE AS TREATMENT OF ANEURYSMAL BONE CYSTS

    ANZ JOURNAL OF SURGERY, Issue 5 2008
    Mark Clayer
    Background: Aneurysmal bone cysts (ABC) are a rare condition in adolescents and teenagers but may result in pain, fracture and growth abnormalities. The gold standard of open curettage carries the risk of surgical complications and still a local recurrence rate of 20,30%. Percutaneous treatment of ABC have rarely been reported and a poor response the usual outcome. This study investigated a new technique of percutaneous aspiration and injection of ABC using an aqueous solution of calcium sulphate. Methods: A radiological diagnosis of a bone cyst was made in 15 consecutive patients and pathologically confirmed as ABC. Most had already sustained a fracture and/or had been previously unsuccessfully treated by minimally invasive techniques including embolization or methylprednisolone injection. The procedure of aspiration and injection with calcium sulphate was undertaken, and the patients were reviewed regularly both clinically and radiologically for a minimum of 2 years. Results: The calcium sulphate cement was reabsorbed completely within 8 weeks. The first osseous response was periosteal new bone formation circumferentially followed by gradual opacification of the cystic cavity. All except one patient that described pain before the procedure reported complete relief of symptoms by 4 weeks. Two patients developed a local recurrence of the cyst, and one subsequently developed a pathological fracture. Two patients sustained pathological fractures through healed cysts, 12 and 22 months after the procedure, respectively. Conclusions: This new technique has shown good early clinical and radiological responses and a low complication rate in a consecutive group of patients with ABC. [source]


    Intraoral Extraction of Cheek Skin Cyst

    DERMATOLOGIC SURGERY, Issue 12 2005
    Richard Bennett MD
    Background. When a physician encounters a benign subcutaneous cyst in the cheek, his or her decision whether to excise and how to excise the cyst takes into account the potential risk of postsurgical scarring. Objective. To describe and show an intraoral buccal mucosal approach to excising a cyst in the inferior-anterior cheek so that skin scarring is avoided. Method. An incision was made intraorally in the buccal mucosa, and dissection was carried through the buccinator muscle until the cyst wall was seen. Careful separation of tissue around the cyst was done by blunt dissection, and the unruptured cyst was removed through the buccal mucosal incision. Result. The entire intact cyst was removed without creating any excision marks in the cheek skin. No complications were encountered, and buccal mucosal healing was excellent. Conclusion. A buccal mucosal intraoral approach is an alternative to a percutaneous excision to remove a cyst in the lower cheek region. The intraoral approach avoids a visible scar on the cheek skin. RICHARD BENNETT, MD, MUBA TAHER, MD, AND JUSTINE YUN, MD, HAVE INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS. [source]


    Giant Multilocular Epidermoid Cyst on the Left Buttock

    DERMATOLOGIC SURGERY, Issue 10 2005
    Alexandros Polychronidis MD
    Background. Epidermoid cysts are the most common cysts of the skin. They are generally small and slow-growing and rarely reach more than 5 cm in diameter. Objective. We present a patient with a giant multilocular epidermoid cyst. Methods. A 75-year-old man presented with a giant, soft, painless, tumorlike mass on the left buttock that had gradually enlarged over a 12-year period. Excision of the mass from the surrounding tissue was extremely easy because of a well-defined capsule. Results. The 28 3 14 3 12 cm mass was totally excised. A histopathologic examination revealed that it was an epidermoid cyst. Conclusion. This rare case of giant epidermoid cyst was treated successfully by local excision followed by primary closure. Dissection of the mass from the surrounding tissue was extremely easy because of a well-defined capsule. [source]


    Staphylococcus aureus Infective Endocarditis Mimicking a Hydatid Cyst

    ECHOCARDIOGRAPHY, Issue 8 2010
    Jeroen Walpot M.D.
    We report an atypical echocardiographic presentation of Staphylococcus aureus infective endocarditis (IE) of the mitral valve in an octogenarian female. Echocardiography revealed perforation of the anterior mitral valve leaflet (AMVL), with a large cystic mass seemingly attached to the AMVL and surrounded by a thin membranous structure. These images were strongly reminiscent of a hydatid cyst. The significant comorbidity of the patient did not justify an urgent surgical approach, and the patient subsequently expired of cardiogenic and septic shock. Autopsy revealed a large vegetation attached to the interatrial septum in the immediate proximity of the AMVL, without signs of the membranous structure and without pathological evidence for septic embolism. This atypical presentation of IE prompted us to discuss a brief review of intracardiac cystic masses. (Echocardiography 2010;27:E80-E82) [source]


    Cyst-based toxicity tests XII,Development of a short chronic sediment toxicity test with the ostracod crustacean Heterocypris incongruens: Selection of test parameters

    ENVIRONMENTAL TOXICOLOGY, Issue 6 2002
    Belgis Chial
    Abstract Experiments were carried out with neonates of the freshwater ostracod Heterocypris incongruens hatched from cysts in order to develop a new culture/maintenance-free solid-phase microbiotest for the toxicity assessment of contaminated sediments. Based on preliminary investigations, a number of test parameters were investigated for a short-chronic assay: hatching time, size of the cups of the multiwell test plates, feeding of the test organisms prior to the test, amount of supplemental algal food, volume of sediment, and duration of the test. On the basis of the findings, a test protocol was formulated for a 6-day assay in 12-cup multiwell plates with 10 organisms per cup and 3 replicates. The test organisms were collected 52 h after the start of the incubation of the cysts in standard freshwater at 25°C under continuous illumination after a 4-h prefeeding with 1.3 mg/mL Spirulina. The test biota in the cups were exposed to 300 ,L of test sediment in 2 mL of standard freshwater with 3 × 107 live algal cells (Raphidocelis subcapitata) as food supplement. Calibrated sand was used as a reference sediment. Mortality and growth of the ostracods were determined after 6 days' incubation at 25°C in darkness. The selected test parameters for the new microbiotest were found adequate for toxicity determination of natural sediments compared with the 10-day contact test with the amphipod Hyalella azteca. © 2002 Wiley Periodicals, Inc. Environ Toxicol 17: 520,527, 2002; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/tox.10085 [source]


    Cyst-based toxicity tests XIII,Development of a short chronic sediment toxicity test with the ostracod crustacean Heterocypris incongruens: Methodology and precision

    ENVIRONMENTAL TOXICOLOGY, Issue 6 2002
    Belgis Chial
    Abstract Experiments were carried out with neonates of the freshwater ostracod Heterocypris incongruens to verify and complete previous choices of test parameters for a new culture/maintenance-free solid-phase microbiotest for freshwater sediments. From trials with increasing volumes of reference sediment, it was concluded that 300 ,L was the most appropriate amount of substrate to be put in 12-cup multiwell plates with 2 mL of standard freshwater. Tests in 3,9 replicates eventually showed that six parallels were needed to have good assay precision (repeatability). Application of the final test protocol to oil-contaminated sediments from the St. Lawrence River in Canada revealed that the 6-day chronic ostracod microbiotest had less variation in repeated tests than did the 10-day contact assay with Hyalella azteca and hence can be considered more precise. Based on the 95% confidence intervals for mortality and growth of the ostracods in the controls (reference sediment) of the 56 tests carried out for the Canadian project, a validity threshold of 20% for mortality was eventually selected, in analogy with the acceptability limits applied in many chronic bioassays. A minimum length of 600 ,m in the control sediment after 6 days' exposure was also taken as the threshold for good health of the test organisms and for reliable test conditions. The new microbiotest has been tailored in a handy and user-friendly new toxkit, the Ostracodtoxkit, which is particularly suited for cost-effective routine monitoring. © 2002 Wiley Periodicals, Inc. Environ Toxicol 17: 528,532, 2002; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/tox.10086 [source]


    Status Epilepticus Presenting in a Patient with Neurosyphilis and a Previously Asymptomatic Arachnoid Cyst

    EPILEPSIA, Issue 7 2002
    Jeffrey D. Jirsch
    No abstract is available for this article. [source]


    A Case With Prepontine (Clival) Arachnoid Cyst Manifested as Trigeminal Neuralgia

    HEADACHE, Issue 10 2008
    Emine Genc MD
    Most cases of "idiopathic" trigeminal neuralgia are thought to originate from vascular compression of the trigeminal root entry zone. In this case, we describe a young man presenting with the symptoms of trigeminal neuralgia associated with a prepontine (clival) arachnoid cyst. [source]


    Respiratory Epithelial Orbital Cyst: Report of a Case and Review of the Literature

    JOURNAL OF CUTANEOUS PATHOLOGY, Issue 1 2005
    S Pasternak
    Orbital cysts include the common epidermoid and dermoid cysts, cysts of conjunctival origin and cysts lined by respiratory-type epithelium. Respiratory epithelial cysts are exceedingly rare and have been reported in common locations for dermoid cysts (superotemporal and superonasal anterior orbit) and in sites atypical for dermoid cysts. Most represent maxillary sinus mucoceles extending into the orbital floor. In some patients, a history of orbital trauma or previous sinus surgery has been implicated in the implantation of the respiratory epithelium in the orbit. Rarely, the respiratory epithelial cyst has been considered to be a choristoma. We report the case of a 72-year-old woman who presented with a cyst in the anterior superotemporal orbit. There was no history of recent or remote trauma. The clinical impression was of a dermoid cyst. Histopathologic examination revealed a cyst lined by non-keratinizing squamous epithelium. A few goblet cells were present and focally, short strips of ciliated mucin secreting columnar cells were identified. The histopathologic findings were those of a respiratory epithelial cyst of the orbit. Given the rarity of this entity, valuable information can be gleaned from critical evaluation and reporting of new cases, in the context of existing data in the literature. [source]


    Effect of Antioxidants During Bovine In Vitro Fertilization Procedures on Spermatozoa and Embryo Development

    REPRODUCTION IN DOMESTIC ANIMALS, Issue 1 2010
    FS Gonçalves
    Contents Increased amounts of reactive oxygen species (ROS) during in vitro fertilization (IVF) may cause cytotoxic damage to gametes, whereas small amounts of ROS favour sperm capacitation. The aim of this study was to investigate the effect of antioxidants [50 ,m,-mercaptoethanol (,-ME) and 50 ,m cysteamine (Cyst)] or a pro-oxidant (5 mm buthionine sulfoximine) on the quality and penetrability of spermatozoa into bovine oocytes and on the subsequent embryo development and quality when added during IVF. Sperm quality, evaluated by the integrity of plasma and acrosomal membranes, and mitochondrial function, was diminished (p < 0.05) after 4-h culture in the presence of antioxidants. Oocyte penetration rates were similar between treatments (p > 0.05), but antioxidants adversely affected the normal pronuclear formation rates (p < 0.05). The incidence of polyspermy was high for ,-ME (p < 0.05). No differences were observed in cleavage rates between treatments (p > 0.05). However, the developmental rate to the blastocyst stage was adversely affected by Cyst treatment (p < 0.05). The quality of embryos that reached the blastocyst stage, evaluated by total, inner cell mass (ICM) and trophectoderm cell numbers and ICM/total cell ratio was unaffected (p > 0.05) by treatments. The results indicate that ROS play a role in the fertilizing capacity in bovine spermatozoa, as well as in the interaction between the spermatozoa and the oocytes. It can be concluded that supplementation with antioxidants during IVF procedures impairs sperm quality, normal pronuclear formation and embryo development to the blastocyst stage. [source]


    Ultrastructure, Eneystment and Cyst Wall Composition of the Resting Cyst of the Peritrich Ciliate Opisthonecta henneguyi

    THE JOURNAL OF EUKARYOTIC MICROBIOLOGY, Issue 1 2003
    PURIFICACIÓN CALVO
    ABSTRACT. The cyst wall of Opisthonecta henneguyi has been studied ultrastructurally and cytochemically by light and electron microscopy, as well as by chemical and electrophoretic analyses, to examine the structure of the cyst wall and its composition. The cyst wall consists of four morphologically distinct layers. The ectocyst is a thin dense layer. The mesocyst is the thickest layer and is composed of a compact material. The endocyst is a thin layer like the ectocyst, but less dense. The granular layer varies in thickness and is composed of a granular material. In the resting cyst, kinetosomes of both oral apparatus and trochal band as well as the myoneme system are maintained, and only cilia are resorbed. The sugars present in the cyst wall are predominantly N-acetylglucosamine (90%) and glucose (10%). The niesocyst is composed of chitin, and the endocyst includes glycoproteins and acid mucopolysaccharides. During secretion of the cyst wall, the endocyst and granular layer are secreted from precursors synthesized "de novo". No cytoplasmic precursors of ectocyst and mesocyst have been detected. [source]


    Patent Piriform Sinus Fistula in a Third Branchial Cleft Cyst

    THE LARYNGOSCOPE, Issue S3 2010
    Deidra A. Blanks MD
    No abstract is available for this article. [source]


    Occult Metastatic Papillary Thyroid Carcinoma Presenting as an Isolated Lateral Cervical Cyst

    THE LARYNGOSCOPE, Issue S3 2010
    Francisco G. Pernas M.D.
    No abstract is available for this article. [source]


    Work Type II First Branchial Cleft Cyst with External Auditory Canal Duplication

    THE LARYNGOSCOPE, Issue S1 2009
    Sandy Mong BS
    No abstract is available for this article. [source]


    Image Cytometry DNA-Analysis of Fine Needle Aspiration Cytology to Aid Cytomorphology in the Distinction of Branchial Cleft Cyst from Cystic Metastasis of Squamous Cell Carcinoma: A Prospective Study,

    THE LARYNGOSCOPE, Issue 11 2004
    Sushma Nordemar MD
    Abstract Objective: Frequently, the distinction between branchial cleft cyst and cystic metastases from squamous cell carcinoma is difficult by cytomorphology. In a prospective study, we investigated the need for, and the value of, image cytometry DNA-analysis as a complement to cytologic evaluation of cystic lesions in the neck. Study Design: Image cytometry DNA-analysis was performed on the fine needle aspiration cytology smears from 50 patients, referred to our department, with a solitary cystic lesion in the lateral region of the neck. Methods: Smears from aspirates were Giemsa stained and cytologically evaluated. Ahrens image analysis was used for DNA analysis on smears stained with Schiff reagent, and lymphocytes were used as control cells. Epithelial cells with DNA values exceeding 5c were regarded as aneuploid, indicating malignancy. Results: Nine lesions were diagnosed as squamous cell cancer metastases cytologically. DNA analysis showed aneuploidy in all of them except one. Three of these lesions had earlier been diagnosed as branchial cleft cyst at the referring hospital. Eight lesions were cytologically inconclusive and four of them were revealed as cystic metastasis at histopathologic analysis, and DNA analysis showed aneuploidy in all but one, which could not be analyzed. Two of these lesions were also diagnosed as branchial cleft cysts at the referring hospital. All benign lesions were diploid. Nine lesions were thyroid and salivary gland lesions. Conclusion: Image cytometry DNA-analysis was shown to help in the distinction between benign and malignant cystic lesions. Thus, when conventional cytomorphology does not suffice, DNA-analysis is clearly a valuable supplement. [source]


    Rathke Cleft Cyst: Diagnostic and Therapeutic Considerations

    THE LARYNGOSCOPE, Issue 10 2002
    Jan L. Kasperbauer MD
    Abstract Objective To highlight diagnostic and therapeutic issues about Rathke cleft cysts for otorhinolaryngologists. Study Design Retrospective. Methods We retrospectively reviewed data collected on Rathke cleft cysts between 1978 and 1998: presenting symptoms, visual acuity, surgical treatment, complications, recurrences, and effect on daily activity. Results Twenty-nine patients were diagnosed with a Rathke cleft cyst (11 male and 18 female patients; mean age, 46 y). The most common presenting symptom was head pain (55%). The majority (59%) of cases demonstrated suprasellar extension on preoperative imaging, with pituitary dysfunction identified in 66%. Recurrence occurred in eight patients (28%). Postoperative visual function improved or remained stable in all patients. Persistent pituitary dysfunction required hormonal supplementation in seven patients (24%). Only one patient with an astrocytoma in addition to a Rathke cleft cyst did not maintain the ability to perform normally on an assessment of activities of daily living, a striking contrast to patients with craniopharyngioma. Conclusions Conclusions were as follows: 1) Rathke cleft cysts must be considered as sources of head pain and pituitary dysfunction. 2) Persistent or recurrent cyst formation occurs in approximately one-third of the patients. Recurrence may take many years, and follow-up imaging is recommended for at least a decade. 3) Maintenance of the ability to perform the activities of normal daily living can be expected after surgical management. 4) Most Rathke cleft cysts can be managed through transnasal exposure of the sella. 5) Packing the sella may result in predisposition to recurrent cyst formation. [source]


    Cyst of the common bile duct in a cat

    AUSTRALIAN VETERINARY JOURNAL, Issue 7 2010
    J-G Grand
    A cyst of the common bile duct (CBD) is reported in a 9-year-old cat that presented with a 1-week history of anorexia, weight loss and vomiting. Diagnosis was established by ultrasound examination and laparotomy, and was ultimately confirmed by histological analysis. Chronic cholangitis and an Escherichia coli species were detected concurrently according to the histopathological findings and bile culture, respectively. The case was managed by suturing the borders of the ostium of the cyst over a stent, using a temporary cholecystostomy tube and antibiotic therapy. At 7 months following the surgery, the cat was in excellent physical condition with no clinical evidence of recurrence of cholangitis or of the cyst after ultrasonographic evaluation. According to the human literature, cysts of the CBD require treatment because of their common association with cholangitis, pancreatitis, and cystic rupture. We were unable to confirm a link between the cyst and cholangitis in this case. It is possible that detection of this anomaly was an incidental finding unrelated to bacterbilia. Histological examination of cyst tissue is mandatory for a definitive diagnosis and to differentiate it from neoplasia. This is the first description of a cyst of the CBD in the cat. [source]


    3464: Surgical treatment of lacrimal gland tumours

    ACTA OPHTHALMOLOGICA, Issue 2010
    D BRISCOE
    Purpose The surgical treatment of Lacrimal gland tumors is often controversial and not so clear cut. Imaging and a full systemic evaluation lead to the decision as to which surgical approach best serves our purposes. The surgical management of Lacrimal gland tumors is discussed and the results of 31 cases in my experience are presented. Methods The surgical approach used is carefully chosen according to the type of disease presentation. All 31 patients in this series had neuroimaging and full work up and 30 underwent incision or excision biopsy. Selected cases are discussed. Results : Surgical Approaches chosen for the Lacrimal gland in this case series included Trans-Septal Orbitotomy, and Lateral Orbitotomy. Disease spectrum included Idiopathic orbital inflammatory disease (8), Orbital Sarcoid (7), Lymphoma (3), Sjrogens disease (3), Benign Mixed Tumour (2), Infectious mononucleosis (2) Angiolymphoid Hyperplasia (2), Sebaceous Cell Carcinoma (1), Churge Strause syndrome (1), Dermoid Cyst (1), Epithelial Inclusion Cyst(1). Conclusion Biopsy of a Lacrimal gland mass is relatively simple and is recommended. The approach should be considered carefully and an excision biopsy should be performed where possible. Surgical management and surprising pathology results can have significant implications for the patient. [source]


    Treatment of Digital Mucous Cysts with Percutaneous Sclerotherapy Using Polidocanol

    DERMATOLOGIC SURGERY, Issue 10 2008
    SUSANA CÓRDOBA MD
    No abstract is available for this article. [source]


    The Surgical Looking Glass: A Readily Available Safeguard Against Eye Splash Injury/Contamination During Infiltration of Anesthesia for Cysts and Other "Porous" Lesions of the Skin

    DERMATOLOGIC SURGERY, Issue 4 2002
    Patrick R. Carrington MD
    Background. "Breaks" in barrier precautions are a definite abrogating influence on the effectiveness of "universal precautions." Dermatologists and dermatologic surgeons are exposed to significant infectious agents on a daily basis, especially due to the high number of minor surgical procedures performed. Backsplash, spray, and eye splash of bodily fluids during these procedures place the surgeon at a high risk of contamination/infection via the conjunctival membranes. The surgical looking glass is a simple utility based on inexpensive equipment already in place in the physician's office which protects the eyes and face during infiltrative anesthesia or incision of cysts and other lesions. Objective. To offer a simple and inexpensive utility to assist with protection from and reduction of contamination/infection of the ocular mucous membranes during surgical procedures. Methods. Utilizing one or two readily available microscope slides overlying the injection site during local infiltrative anesthesia, backsplash or spray can be contained. Results. This utility is effective in containment of backsplash or spray of anesthesia or bodily fluids during even minor surgical procedures. Conclusion. The surgical looking glass can enhance safety and promote "universal precautions" during even minor surgical procedures or infiltration of anesthesia into more porous areas or lesions for the practicing dermatologist or dermatologic surgeon. The pragmatic, practical, and inexpensive nature of the surgical looking glass invites its use on a daily basis by the practicing dermatologist. [source]


    Regarding Treatment of Myxoid Cysts

    DERMATOLOGIC SURGERY, Issue 3 2002
    Emanuel G. Kuflik MD
    No abstract is available for this article. [source]


    Molecular cytogenetic characterization of early and late renal cell carcinomas in Von Hippel-Lindau disease ,

    GENES, CHROMOSOMES AND CANCER, Issue 1 2001
    John L. Phillips
    Deletions of 3p25, gains of chromosomes 7 and 10, and isochromosome 17q are known cytogenetic aberrations in sporadic renal cell carcinoma (RCC). In addition, a majority of RCCs have loss of heterozygosity (LOH) of the Von Hippel-Lindau (VHL) gene located at chromosome band 3p25. Patients who inherit a germline mutation of the VHL gene can develop multifocal RCCs and other solid tumors, including malignancies of the pancreas, adrenal medulla, and brain. VHL tumors follow the two-hit model of tumorigenesis, as LOH of VHL, a classic tumor suppressor gene, is the critical event in the development of the neoplastic phenotype. In an attempt to define the cytogenetic aberrations from early tumors to late RCC further, we applied spectral karyotyping (SKY) to 23 renal tumors harvested from 6 unrelated VHL patients undergoing surgery. Cysts and low-grade solid lesions were near-diploid and contained 1,2 reciprocal translocations, dicentric chromosomes, and/or isochromosomes. A variety of sole numerical aberrations included gains of chromosomes 1, 2, 4, 7, 10, 13, 21, and the X chromosome, although no tumors had sole numerical losses. Three patients shared a breakpoint at 2p21,22, and three others shared a dicentric chromosome 9 or an isochromosome 9q. In contrast to the near-diploidy of the low-grade lesions, a high-grade lesion and its nodal metastasis were markedly aneuploid, revealed loss of VHL by fluorescence in situ hybridization (FISH), and contained recurrent unbalanced translocations and losses of chromosome arms 2q, 3p, 4q, 9p, 14q, and 19p as demonstrated by comparative genomic hybridization (CGH). By combining SKY, CGH, and FISH of multiple tumors from the same VHL kidney, we have begun to identify chromosomal aberrations in the earliest stages of VHL-related renal cell tumors. Our current findings illustrate the cytogenetic heterogeneity of different VHL lesions from the same kidney, which supports the multiclonal origins of hereditary RCCs. Published 2001 Wiley-Liss, Inc. [source]


    Our experience in eight cases with urinary hydatid disease: A series of 372 cases held in nine different clinics

    INTERNATIONAL JOURNAL OF UROLOGY, Issue 9 2006
    LMAZ
    Objectives: Hydatid disease, a parasitic infestation caused by the larval stage of the cestode Echinococcus granulosus, is diagnosed commonly in the east and south-east regions of Turkey. The aim of this study is to emphasize the relatively frequent occurrences of echinococcosis in our region, and to discuss therapeutic options and treatment results according to current literature. Methods: A retrospective 10-year review of nine different clinics' records of the Research Hospital of the Medical School of Yüzüncü Y,l University revealed 372 hydatid disease cases that were localized in various organs and treated surgically (271 cases) or drained percutaneously (99 cases). Hydatid disease was diagnosed by ultrasonography (US) and computed tomography scans (CT) and confirmed histopathologically. Results: The involved organ was lung in 203 cases (131 adults, 72 children), liver in 150, spleen in 9, brain in 2, kidneys in 7 cases and the retrovesical area in 1 case. The urogenital system is involved at a rate of 2.15%. Two hundred and seventy-one cases were treated surgically and 99 percutaneously. Two cases with renal hydatid cyst refused the surgical procedure (one had a solitary kidney with hydatid cyst). Albendazole was administered to 192 patients; 93 patients had open surgical procedure and 99 patients underwent percutaneous procedure. Cysts were excised totally in the open surgical procedure; however, involved kidneys were removed totally (four cases) except one. Cystectomy and omentoplasty was performed in one case. Complications were as follows: in six cases, cystic material was spilled into the bronchial cavity during the dissection and a renal hydatid cyst ruptured and spilled retroperitoneally. Conclusion: Hydatid disease is a serious health problem in Turkey. The mainly affected organs are liver and lung. It can be treated surgical or by percutaneous aspiration. [source]


    A New Species of Streptocephalus Fairy Shrimp (Crustacea, Anostraca) with Tetrahedral Cysts from Central Thailand

    INTERNATIONAL REVIEW OF HYDROBIOLOGY, Issue 3 2006
    La-Orsri Sanoamuang
    Abstract A new species of fairy shrimp, Streptocephalus siamensis n. sp., is described from five temporary pools in Suphan Buri and Kanchana Buri Provinces, central Thailand. It sometimes co-occurs with its congener, S. sirindhornae . This new species belongs to the subgenus Parastreptocephalus which is defined by bearing tetrahedral cysts. This is the third anostracan species reported from Thailand. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]


    Type and ultrastructure of Didymocystis wedli and Koellikerioides intestinalis (Digenea, Didymozoidae) cysts in captive Atlantic bluefin tuna (Thunnus thynnus Linnaeus, 1758)

    JOURNAL OF APPLIED ICHTHYOLOGY, Issue 6 2009
    I. Mladineo
    Summary Tissue encapsulation, one of the most common tissue reactions to invading parasites, is the hallmark sign of didymozoid (Digenea, Didymozoidae) infections in fish. Investigated were the types of intermediate filaments and ultrastructure of the connective tissue capsule elicited by the presence of didymozoids in the gills and intestine of Atlantic bluefin tuna (Thunnus thynnus Linnaeus, 1758). The evaluation was done performing TEM microscopy of two tissue-embedded didymozoid species, along with monoclonal antibodies labeling (anti-fish collagen type I, anti-human cytokeratin, anti-vimentin antibodies). Ultrastructure of Didymocystis wedli (Ariola, 1902) (prevalence = 61.75%, abundance = 28.91) encapsulated in gill filaments and Koellikerioides intestinalis (Yamaguti, 1970) (prevalence = 54.65%, abundance = 10.96) in the intestinal submucosa showed that the thin parasitic hindbody tegumentum was directly embedded in layers of connective tissue bands. Only a few cellular elements (lymphocytes, fibroblasts and fibrocytes) infiltrated the connective tissue capsule, which differed between the two didymozoid species in thickness, not in the type of filaments expressed. Cysts showed positive reaction to extracellular collagen as well as appearing positive for the cytoskeletal intermediate filaments vimentin and cytokeratin. [source]


    Combined Medical and Surgical Treatment of Intracardiac Hydatid Cysts in 11 Patients

    JOURNAL OF CARDIAC SURGERY, Issue 2 2010
    Alireza Molavipour M.D.
    We report 11 cases of cardiac hydatidosis who were treated medically and surgically. Patients and methods: Eleven patients diagnosed with cardiac echinococcosis were referred to the Cardiac Surgery Department of Shahid Madani Hospital from 1992 to 2004. Symptoms included dyspnea, palpitation, limb ischemia, fever, weight loss, hemiplegia, and loss of consciousness. Patients underwent surgical removal of the cyst followed by medical treatment until the titer of echinococcus hemaglutination test came to normal. Results: Hospital stay and recovery time were uneventful in nine patients. One patient died due to acute renal failure before hospital discharge (9%) and another patient experienced cerebral hydatidosis 12 months after surgery (probably due to cyst embolism). The other nine patients had no complications during five years of follow-up. Conclusion: Surgical excision using cardiopulmonary bypass combined with medical therapy provides the most optimal treatment for cardiac echinococcosis.,(J Card Surg 2010;25:143-146) [source]


    CYST,THECA RELATIONSHIP, LIFE CYCLE, AND EFFECTS OF TEMPERATURE AND SALINITY ON THE CYST MORPHOLOGY OF GONYAULAX BALTICA SP.

    JOURNAL OF PHYCOLOGY, Issue 4 2002
    NOV. (DINOPHYCEAE) FROM THE BALTIC SEA AREA
    A new species of Gonyaulax, here named Gonyaulax baltica sp. nov., has been isolated from sediment samples from the southeastern Baltic. Culture strains were established from individually isolated cysts, and cyst formation was induced in a nitrogen-depleted medium. Although G. baltica cysts are similar to some forms attributed to Spiniferites bulloideus and the motile stage of G. baltica has affinities with G. spinifera, the combination of features of cyst and motile stage of G. baltica is unique. The culture strains were able to grow at salinity levels from 5 to 55 psu and formed cysts from 10 to 50 psu. Cultures at each salinity level were grown at 12, 16, and 20° C. Temperature- and salinity-controlled morphological variability was found in the resting cysts. Central body size varied with temperature and salinity, and process length varied with salinity. Cysts that formed at extreme salinity levels displayed lower average process length than cysts formed at intermediate salinity levels, and central body length and width were lowest at higher temperature and lower salinity. Models for the relationship between central body size and temperature/salinity and process length and salinity have been developed and may be used to determine relative paleosalinity and paleotemperature levels. Our results on salinity-dependent process length confirm earlier reports on short-spined cysts of this species found in low salinity environments, and the model makes it possible to attempt to quantify past salinity levels. [source]