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Criteria Used (criterion + used)

Distribution by Scientific Domains

Medical Sciences	50%
Life Sciences	11%
Business, Economics, Finance and Accounting	8%
Engineering	6%
Earth and Environmental Science	4%
Chemistry	4%
Psychology	3%
Education	3%
5 Other Domains	11%

Selected Abstracts

Characterizing regime shifts in the marine environment

FISH AND FISHERIES, Issue 2 2006
Kathryn Lees
Abstract Recent years have seen a plethora of studies reporting that ,regime shifts' have occurred in the North Atlantic and Pacific Oceans during the last century. In many cases, the criteria used to distinguish a regime shift have not been explicitly stated. In other cases, a formal definition has been proposed and the data set assessed against it. Developing a universal quantitative definition for identifying and distinguishing between purported climatic and ecological regime shifts has proved problematic as many authors have developed criteria that seem unique to the system under study. Consequently, they throw little light on the drivers of ecological regime shifts. Criteria used to define regime shifts are reviewed and on the basis of evidence from purported regime shifts, common characteristics in the speed and amplitude of the changes and the duration of quasi-stable states are used to propose a more clearly defined set of criteria for defining climatic and ecological regime shifts. Causal drivers of regime shifts are explored using correlation analysis. Limitations of these methods are discussed. [source]

A model for online learner support based on selecting appropriate peer tutors

JOURNAL OF COMPUTER ASSISTED LEARNING, Issue 6 2008
P. Van Rosmalen
Abstract Tutors have only limited time to support students. In this paper, we discuss a model that addresses the question of how to help students answer content-related questions. A small group of students is created, which consists of the student who asked the question and peers who should be able to answer it. Criteria used to compose the group are the content of the question in relation to the knowledge and skills of the peers. The model supports the collaboration with text fragments selected from the study materials. We will introduce the model and briefly discuss the results of the calibration and a simulation of the model. Finally, we will discuss the outcome of an experiment with two groups of approximately 50 students who used the model for a period of 8 weeks. The results indicate that the students positively value the model and that it is possible to resolve a substantial number of their questions. [source]

Management and Outcome of Patients With Mucoepidermoid Carcinoma of Major Salivary Gland Origin: A Single Institution's 30-Year Experience,

THE LARYNGOSCOPE, Issue 2 2008
Katri Aro MD
Abstract Background: Mucoepidermoid carcinoma (MEC) is one of the most frequent epithelial malignancies of the salivary glands. Prediction of clinical outcome of MEC is challenging. Material and Methods: We retrospectively reviewed 52 cases of MEC of major salivary gland origin diagnosed at the Department of Otolaryngology,Head and Neck Surgery, Helsinki University Central Hospital, Helsinki, Finland, during a 30-year period of 1976 to 2005. Criteria used for diagnosis were those of World Health Organization classifications valid at each time point, and criteria for grading were those recommended by Armed Forces Institute of Pathology fascicle (1996). Since 1993, the degree of cell proliferation was used at our institution as an adjunct tool when grading MEC. The majority of cases occurred in the parotid gland (n = 47, 90%) followed by the submandibular gland (n = 5, 10%). Results: We had 39% high-grade (HG), 14% intermediate-grade (IMG), and 44% low-grade (LG) MECs. T categories were T1, n = 18; T2, n = 16; T3, n = 9; T4, n = 9. Forty-nine (94%) patients were treated with curative intent. These patients underwent surgery, and 24 (49%) patients received postoperative radiotherapy. Follow-up time varied from 6 months to 9 years. Forty-five percent of HG-MEC patients and 67% of IMG-MEC patients developed locoregional failures or distant metastases during a 3-year follow-up as opposed to none of the LG-MEC patients. Of MEC patients with N0 neck, two HG-MEC patients and one IMG-MEC (8%) patient developed regional recurrence during follow-up. Conclusions: Patient outcome in the different grades of MEC suggests a need for overview of the treatment protocol, especially with regard to LG-MEC and IMG-MEC. The apparently unusual occurrence of locoregional failures and metastases in LG-MEC suggests a restrictive approach in surgical management. However, the frequent occurrence of such failures in IMG-MEC warrants an aggressive approach with these tumors. [source]

A Risk-Cost Optimized Maintenance Strategy for Corrosion-Affected Concrete Structures

COMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 5 2007
Chun-Qing Li
It is also observed that some severely deteriorated concrete structures survive for many years without maintenance. This raises the question of why and how to maintain corrosion-affected concrete structures, in particular in the climate of an increasing scarcity of resources. The present article attempts to formulate a maintenance strategy based on risk-cost optimization of a structure during its whole service life. A time-dependent reliability method is employed to determine the probability of exceeding a limit state at each phase of the service life. To facilitate practical application of the formulated maintenance strategy, an algorithm is developed and programmed in a user-friendly manner with a worked example. A merit of the proposed maintenance strategy is that models used in risk assessment for corrosion-affected concrete structures are related to some of the design criteria used by practitioners. It is found in the article that there exists an optimal number of maintenances for cracking and delamination that returns the minimum total cost for the structure in its whole life. The maintenance strategy presented in the article can help structural engineers, operators, and asset managers develop a cost-effective management scheme for corrosion-affected concrete structures. [source]

Assessing the Effectiveness of Reserve Acquisition Programs in Protecting Rare and Threatened Species

CONSERVATION BIOLOGY, Issue 6 2006
WILL R. TURNER
Lake Wales Ridge (Florida); especies en peligro; índice de protección; Lista Roja IUCN; matorral Abstract:,Measuring the effectiveness of reserve networks is essential to ensure that conservation objectives such as species persistence are being met. We devised a new approach for measuring the effectiveness of land conservation in protecting rare and threatened species and applied it to an ecosystem of global significance. We compiled detailed global distributional data for 36 rare and threatened plants and animals found in the Lake Wales Ridge ecosystem in central Florida (U.S.A.). For each species, we developed a set of protection indices based in part on criteria used to categorize species for the World Conservation Union's Red List. We calculated protection indexes under three different conservation scenarios: a past scenario, which assumed recent, major land-acquisition efforts never occurred; a current scenario, which assumed no additional areas are saved beyond what is currently protected; and a targeted scenario, which assumed all of the remaining areas targeted for protection are eventually acquired. This approach enabled us to quantify the progress, in terms of reduced risk of extinction, that conservationists have made in protecting target species. It also revealed the limited success these land-acquisition efforts have had in reducing those extinction risks associated with loss of habitat or small geographic ranges. Many species of the Lake Wales Ridge will remain at high risk of extinction even if planned land-acquisition efforts are completely successful. By calculating protection indexes with and without each site for all imperiled species, we also quantified the contribution of each protected area to the conservation of each species, enabling local conservation decisions to be made in the context of a larger (global) perspective. The protection index approach can be adapted readily to other ecosystems with multiple rare and threatened species. Resumen:,La cuantificación de la efectividad de las redes de reservas es esencial para asegurar que objetivos, como la persistencia de especies, se cumplan. Diseñamos un nuevo método para medir la efectividad de la conservación de tierras en la protección de especies raras y amenazadas y lo aplicamos a un ecosistema de importancia global. Compilamos datos detallados de la distribución global de 36 especies raras y amenazadas de plantas y animales que se encuentran en el ecosistema de la Lake Wales Ridge en el centro de Florida (E.U.A.). Para cada especie desarrollamos un conjunto de índices de protección basado parcialmente en criterios utilizados para clasificar especies para la Lista Roja de la Unión Mundial para la Naturaleza. Calculamos los índices de protección bajo tres escenarios de conservación distintos: un escenario pasado, que asumía que los esfuerzos recientes de adquisición de tierras nunca ocurrieron; un escenario actual, que asumía que no se protegen áreas adicionales a las ya conservadas; y un escenario deseado, que asumía que todas las áreas consideradas para ser protegidas son adquiridas eventualmente. Este método nos permitió cuantificar el progreso, en términos de la reducción del riesgo de extinción, en la protección de las especies obtenido por conservacionistas. También reveló el éxito limitado de los esfuerzos de adquisición de tierras en la disminución de los riesgos de extinción asociados con la pérdida de hábitat o con rangos geográficos pequeños. Se pronosticó que muchas especies de la Lake Wales Ridge permanecerán en alto riesgo aun si los esfuerzos de adquisición de tierra planificados son completamente exitosos. Al calcular los índices de protección con y sin cada sitio para todas las especies en peligro, también cuantificamos la contribución de cada área protegida a la conservación de cada especie, lo que permite que las decisiones de conservación se tomen en el contexto de una perspectiva mayor (global). El método del índice de protección se puede adaptar fácilmente a otros ecosistemas con múltiples especies raras y amenazadas. [source]

Usefulness of skin testing in cutaneous drug eruptions in routine practice

CONTACT DERMATITIS, Issue 3 2009
Tatiana Tchen
Background: Cutaneous drug eruptions are common side-effects. The imputation score combining intrinsic (chronology, clinical and paraclinical signs) and extrinsic criteria used in Pharmacovigilance Centres is insufficient alone to identify with certainty a responsible drug. Objective: To evaluate the imputation score before and after performing skin testing in patients with cutaneous drug eruptions. Patients/Methods: A single-centre retrospective study was performed on 339 patients tested between 2001,2006. Imputation scores were calculated before and after skin tests for each cutaneous drug eruption according to the clinical type of skin eruption and the type of drug. Results: Among 121 patients meeting inclusion criteria, 46% showed an increase of the imputation score as shown by 25/41 cases of maculo-papular exanthema, 4/11 cases of acute generalized exanthematous pustulosis and 17/41 cases of urticaria/anaphylaxis. The imputation score increased in 25/70 cases of the tested antibiotic drugs, in 14/56 cases of cardiovascular drugs, and it increased in 19 patients (34%) with I1 or I2 imputation scores before skin testing and in 29 (52%) with an I3 imputation score before skin testing. Conclusions: Drug skin testing appeared useful in investigating cutaneous drug eruptions in routine practice, including not only drugs with a high imputation score (I3) but also those with a lower score (I1, I2). Drug skin testing should lead to oral rechallenge of drugs with negative tests in order to determine which drugs may be used safely. [source]

A systematic review of the diagnostic classifications of traumatic dental injuries

DENTAL TRAUMATOLOGY, Issue 2 2006
Karla Maria Pugliesi da Costa Feliciano
Abstract,,, A systematic review of the literature was undertaken to evaluate the criteria used for the diagnostic classification of traumatic dental injuries from an epidemiological standpoint. The methodology used was that suggested by the Cochrane Collaboration and the National Health Service. A total of 12 electronic bibliographical databases (BBO, BioMed Central, Blackwell Synergy, Cochrane, DARE, EMBASE, HighWire, LILACS, MEDLINE, PubMed Central, SciELO, SciSearch) and the World Wide Web were searched. There was no attempt to specify the strategy in relation to date, study design, or language. The last search was performed in May 2003. Two reviewers screened each record independently for eligibility by examining titles, abstracts, keywords and using a standardized reference form. Disagreements were resolved through consensus. The final study collection consisted of 164 articles, from 1936 to 2003, and the population sample ranged from 38 to 210 500 patients. 54 distinct classification systems were identified. According to the literature, the most frequently used classification system was that of Andreasen (32%); as regards the type of injury, the uncomplicated crown fracture was the most mentioned lesion (88.5%). Evidence supports the fact that there is no suitable system for establishing the diagnosis of the studied injuries that could be applied to epidemiological surveys. [source]

Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels

DEVELOPMENTAL DYNAMICS, Issue 7 2008
Emma J. Gordon
Abstract Expression of the hyaluronan receptor LYVE-1 is one of few available criteria used to discriminate lymphatic vessels from blood vessels. Until now, endothelial LYVE-1 expression was reported to be restricted to lymphatic vessels and to lymph node, liver, and spleen sinuses. Here, we provide the first evidence that LYVE-1 is expressed on blood vessels of the yolk sac during mouse embryogenesis. LYVE-1 is ubiquitously expressed in the yolk sac capillary plexus at E9.5, then becomes progressively down-regulated on arterial endothelium during vascular remodelling. LYVE-1 is also expressed on intra-embryonic arterial and venous endothelium at early embryonic stages and on endothelial cells of the lung and endocardium throughout embryogenesis. These findings have important implications for the use of LYVE-1 as a specific marker of the lymphatic vasculature during embryogenesis and neo-lymphangiogenesis. Our data are also the first demonstration, to our knowledge, that the mouse yolk sac is devoid of lymphatic vessels. Developmental Dynamics 237:1901,1909, 2008. © 2008 Wiley-Liss, Inc. [source]

The significance of the diagnosis of atypia in breast fine-needle aspiration

DIAGNOSTIC CYTOPATHOLOGY, Issue 5 2004
Jennifer C. Lim M.D.
Abstract The diagnosis of atypia in breast fine-needle aspiration (FNA) continues to be an area of debate in cytology practice. The aim of this study was to assess the clinical significance of this term and to evaluate potential morphological criteria, which would determine the patient's outcome. A computer-based search was carried out to retrieve breast FNAs performed between 1990 and 2000 that were diagnosed as atypical. Cases followed by surgical resection were reexamined for the presence of morphological features potentially differentiating benign and malignant lesions. Out of 1,568 breast FNAs, there were 64 cases (4%) with a diagnosis of atypia. Thirty-eight cases had surgical follow-up material that revealed malignancy in 14 cases (37%) and benign lesions in 24 cases (63%). The benign diagnostic categories included fibrocystic change (12/24), fibroadenoma (3/24), tubular adenoma (2/24), and nonspecific findings (7/24). The malignant diagnoses included ductal carcinoma (9/14), lobular carcinoma (3/14), ductal carcinoma in situ (DCIS; 1/14), and tubular carcinoma (1/14). The evaluation of cytological criteria used to differentiate benign from malignant lesions (i.e., cellularity, loss of cohesion, myoepithelial cells, nuclear enlargement, nuclear overlap, prominent nucleoli) revealed significant overlap between benign and malignant cases, particularly in cases of fibroadenoma, tubular adenoma, and proliferative breast disease. The surgical follow-up of four hypocellular cases revealed lobular carcinoma in two cases and ductal carcinoma in the remaining two cases. Our study confirmed that the diagnosis of atypia is clinically significant because it is associated with a high probability of malignancy. No morphological criterion is able to reliably differentiate benign and malignant lesions in cases diagnosed with atypia. Diagnosis of atypia is particularly significant in hypocellular cases. We recommended that breast FNAs with a diagnosis of atypia be evaluated further histologically. Diagn. Cytopathol. 2004;31:285,288. © 2004 Wiley-Liss, Inc. [source]

Is the originality of a species measurable?

ECOLOGY LETTERS, Issue 6 2005
Sandrine Pavoine
Abstract In this paper, we introduce the concept of ,originality of a species within a set' in order to indicate the average rarity of all the features belonging to this species. Using a phylogenetic tree of 70 species of New World terrestrial Carnivora, we suggest measuring the originality by a probability distribution. This maximizes the expected number of features shared by two species randomly drawn from the set. By using this new index, we take account of branch lengths whereas current indices of originality focus on tree topology. As a supplement to Nee and May's optimizing algorithm, we find that originality must be one of the criteria used in conservation planning. [source]

Does mother really know best?

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, Issue 3 2005
Oviposition preference reduces reproductive performance in the generalist parasitoid Aphidius ervi
Abstract The reproductive success of female parasitoids is dependent on their ability to accurately assess the suitability of a host for larval development. For generalist parasitoids, which utilize a broad range of species and instars as hosts, a set of assessment criteria determines whether a host is accepted or rejected. The suitability of a host, however, can only be imperfectly assessed by the female parasitoid, which can result in the selection of lesser quality hosts for oviposition. In this study we explored the disparity between host quality and host preference using the generalist koinobiotic parasitoid Aphidius ervi Haliday (Hymenoptera: Aphidiidae) and the host Aulacorthum solani (Harris) (Homoptera: Aphididae), the foxglove aphid. The second instar hosts produced the highest level of reproductive success, while third and fourth instars resulted in a substantially reduced reproductive performance. When given a choice of host instars, parasitoids preferred the older hosts for oviposition disregarding their reduced suitability for larval development. Results are discussed in context of mechanisms involved in A. ervi host selection and biases in the criteria used to assess hosts that may arise when parasitoids transfer host species between generations. [source]

Recommendation for a definition of acute symptomatic seizure

EPILEPSIA, Issue 4 2010
Ettore Beghi
Summary Purpose:, To consider the definition of acute symptomatic seizures for epidemiological studies, and to refine the criteria used to distinguish these seizures from unprovoked seizures for specific etiologies. Methods:, Systematic review of the literature and of epidemiologic studies. Results:, An acute symptomatic seizure is defined as a clinical seizure occurring at the time of a systemic insult or in close temporal association with a documented brain insult. Suggestions are made to define acute symptomatic seizures as those events occurring within 1 week of stroke, traumatic brain injury, anoxic encephalopathy, or intracranial surgery; at first identification of subdural hematoma; at the presence of an active central nervous system (CNS) infection; or during an active phase of multiple sclerosis or other autoimmune diseases. In addition, a diagnosis of acute symptomatic seizure should be made in the presence of severe metabolic derangements (documented within 24 h by specific biochemical or hematologic abnormalities), drug or alcohol intoxication and withdrawal, or exposure to well-defined epileptogenic drugs. Discussion:, Acute symptomatic seizures must be distinguished from unprovoked seizures and separately categorized for epidemiologic purposes. These recommendations are based upon the best available data at the time of this report. Systematic studies should be undertaken to better define the associations in question, with special reference to metabolic and toxic insults, for which the time window for the occurrence of an acute symptomatic seizure and the absolute values for toxic and metabolic dysfunction still require a clear identification. [source]

Correlation between routine radiographic findings and early racing career in French Trotters

EQUINE VETERINARY JOURNAL, Issue S36 2006
C. ROBERT
Summary Reasons for performing study: The relationship between the presence of radiological abnormalities and subsequent racing performance is controversial. However, as training is expensive and time consuming, it would save time and money to identify subjects with osteo-articular lesions not compatible with a normal racing career on the basis of routine radiographic screenings at yearling age. Objectives: To evaluate the impact of osteo-articular lesions on racing ability in French Trotters and identify radiographic changes associated with failure in ,qualification', in order to provide objective criteria for selection of horses based on their osteo-articular status. Hypothesis: The influence of radiographic findings (RF) on racing ability depends on their nature, location, clinical relevance and number. Methods: The limbs of 202 French Trotters were radiographed just before they started training. All the RF were graded according to a standardised protocol depending on their severity. The success in ,qualification' (first race in career of French Trotters) was the criteria used to assess racing ability. Breeders and trainers were questioned about the causes for horses not racing. Results: Overall 113 (55.9%) horses qualified. Osteoarticular lesions were directly responsible for nonqualification in 31% of the horses. Subjects with more than one abnormal RF, with abnormal RF on the fore-, hind-fetlock or proximal tarsus were less likely to qualify. Dorsal modelling in the front fetlock and osteochondrosis of the lateral trochlear ridge of the femur also significantly reduced the qualification rate. Conclusions: Most RF are compatible with beginning a racing career, but severe RF or multiple abnormal RF significantly compromise future racing career. Potential relevance: This study supports the use of routine radiographic programmes for detection of osteoarticular lesions in yearlings. A synthetic radiographic score, based on both the severity and the number of lesions, could be useful for breeders and trainers as complementary information to select their horses. [source]

Improving clinical assessment: evaluating students' ability to identify and apply clinical criteria

EUROPEAN JOURNAL OF DENTAL EDUCATION, Issue 3 2010
C. Redwood
Abstract Aim:, There is ongoing concern by health educators over the inability of professionals to accurately self-assess their clinical behaviour and standards, resulting in doubts over a key expectation of effective self-regulation in the health professions. Participation by students in the assessment process has been shown to increase the understanding of assessment criteria in written assessment tasks. How this might transfer to the clinical setting is the focus of this study. This paper is part of an ongoing investigation of the impact on learning of a series of activities that provides students with opportunities to discuss and apply criteria and standards associated with self-assessment in clinical dentistry. Our aim was to evaluate whether participation in these assessment activities improved the ability of first-year dental students to recognise behaviours demonstrated by ,peers' in videos of clinical scenarios and to relate these to the assessment criteria. Materials and methods:, A series of three workshops in conjunction with weekly clinical assessment activities in Semesters 1 and 2 were use to support first-year students' learning of clinical assessment criteria. The design of the workshops was based on the principles of social constructivist theories of learning and the concept of tacit knowledge. Accordingly workshop activities were planned around videos that were specifically constructed to illustrate procedures and behaviours typical of those observed by staff and tutors in the first year of the dental course at The University of Adelaide, Australia. First-year students viewed the videos prior to and after the workshops and recorded observed behaviours that related to the assessment criteria that were used in their clinical practice course. Student learning outcomes were assessed 10,14 weeks after the initial workshop and again up to 42 weeks later. To check whether learning resulted from repeated viewing of the videos without formal discussion, a reference group of third-year students who did not attend the workshops also viewed the videos two times, separated by 12 weeks, and recorded observations in the same way. Results:, There was no consistent evidence that repeat viewing of the videos in isolation resulted in improved recognition of ,peer' behaviours by third-year dental students. Results for the first-year students indicated that the workshops and clinical assessment activities had a significantly positive effect on the ability of students to identify ,peer' behaviours related to the criteria used for clinical assessment. In particular, students' recognition in others of knowledge and professional behaviours improved significantly. This improvement was retained over the year and students were able to recognise these behaviours in other scenarios relevant to their year level. Conclusions:, This early exposure to the process of clinical assessment, coupled with ongoing self-assessment and tutor feedback throughout first year, improved the ability of first-year students to identify and apply some key assessment criteria to observed ,peer' behaviour, and this ability was retained over time. [source]

Risk factors for alcoholic liver disease

ADDICTION BIOLOGY, Issue 3 2000
Stefano Bellentani
Alcoholic liver disease (ALD) is still a frequent disorder, even though its incidence appears to be decreasing. In spite of intense investigation, the precise mechanisms leading to ALD are still imprecisely known. This is due in part to the lack of a reliable animal model; in part to the difficulty of obtaining clinical data of adequate sample size and derived from unblased populations and finally from the lack of uniformity of the criteria used to define ALD. This paper will review what is known of the various pieces of this puzzle, with particular emphasis not only on the total amount of alcohol consumed, but also on drinking patterns and type of alcoholic beverage ingested. The other potential factors such as age, gender, genetic background, nutritional status, occupational hazards and viral diseases (especially HCV infection) will be touched upon. [source]

The Anisotropic Fatigue Behavior of Forged Steel,

ADVANCED ENGINEERING MATERIALS, Issue 9 2009
Etienne Pessard
This paper deals with the anisotropic fatigue behavior of a bainitic steel and aims at improving the fatigue criteria used for the design of forged components. The two different types of anisotropic fatigue behavior observed in the literature are discussed. Experimental results are presented for a hot-rolled steel which demonstrates the effect of elongated inclusions on the fatigue behavior. A model is proposed to account for the anisotropic fatigue behavior. [source]

Characterizing regime shifts in the marine environment

Selection Criteria for Emergency Medicine Residency Applicants

ACADEMIC EMERGENCY MEDICINE, Issue 1 2000
Joseph T. Crane MD
Abstract: Objectives: To determine the criteria used by emergency medicine (EM) residency selection committees to select their residents, to determine whether there is a consensus among residency programs, to inform programs of areas of possible inconsistency, and to better educate applicants pursuing careers in EM. Methods: A questionnaire consisting of 20 items based on the current Electronic Residency Application Service (ERAS) guidelines was mailed to the program directors of all 118 EM residencies in existence in February 1998. The program directors were instructed to rank each item on a five-point scale (5 = most important, 1 = least important) as to its importance in the selection of residents. Followup was done in the form of e-mail and facsimile. Results: The overall response rate was 79.7%, with 94 of 118 programs responding. Items ranking as most important (4.0-5.0) in the selection process included: EM rotation grade (mean ± SD = 4.79 ± 0.50), interview (4.62 ± 0.63), clinical grades (4.36 ± 0.70), and recommendations (4.11 ± 0.85). Moderate emphasis (3.0-4.0) was placed on: elective done at program director's institution (3.75 ± 1.25), U.S. Medical Licensing Examination (USMLE) step II (3.34 ± 0.93), interest expressed in program director's institution (3.30 ± 1.19), USMLE step I (3.28 ± 0.86), and awards/achievements (3.16 ± 0.88). Less emphasis (<3.0) was placed on Alpha Omega Alpha Honor Society (AOA) status (3.01 ± 1.09), medical school attended (3.00 ± 0.85), extracurricular activities (2.99 ± 0.87), basic science grades (2.88 ± 0.93), publications (2.87 ± 0.99), and personal statement (2.75 ± 0.96). Items most agreed upon by respondents (lowest standard deviation, SD) included EM rotation grade (SD 0.50), interview (SD 0.63), and clinical grades (SD 0.70). Of the 94 respondents, 37 (39.4%) replied they had minimum requirements for USMLE step I (195.11 ± 13.10), while 30 (31.9%) replied they had minimum requirements for USMLE step II (194.27 ± 14.96). Open-ended responses to "other" were related to personal characteristics, career/goals, and medical school performance. Conclusions: The selection criteria with the highest mean values as reported by the program directors were EM rotation grade, interview, clinical grades, and recommendations. Criteria showing the most consistency (lowest SD) included EM rotation grade, interview, and clinical grades. Results are compared with those from previous multispecialty studies. [source]

Headache and Psychological Functioning in Children and Adolescents

HEADACHE, Issue 9 2006
Scott W. Powers PhD
Headache can affect all aspects of a child's functioning, leading to negative affective states (eg, anxiety, depression, anger) and increased psychosocial problems (for instance, school absences, problematic social interactions). For children and adolescents who experience frequent headache problems, comorbid psychological issues are a well-recognized, but poorly understood, clinical phenomenon. The confusion surrounding the relationship between pediatric headache and psychopathology exists for several reasons. First, in some cases, headache has been inappropriately attributed to psychological or personality features based on anecdotal observations or interpretations that go beyond the available data. Additionally, measures of psychopathology have not always adhered to the American Psychiatric Association's diagnostic criteria, thus reducing the reliability of diagnostic judgments. Furthermore, the diagnosis of headache has not always followed standard criteria, and has been complicated by the emergence of new terms and evolving measures. Finally, methodological shortcomings, such as incomplete descriptions of the procedures and criteria used for the study, inadequate descriptions of headache severity, lack of a control group for comparison with individuals without headaches, reliance primarily on cross-sectional research designs that are often discussed with inferences to causal hypotheses, and the use of unstandardized assessment measures, have significantly limited the validity of research findings. The goal of the current review is to examine the extant literature to provide the most up-to-date picture on what the research has made available about the magnitude, specificity, and causes of psychopathology in children and adolescents with headache, in an effort to further elucidate their relationship and prompt a more methodologically rigorous study of these issues. [source]

Alternative approaches to obtain optimal bid values in contingent valuation studies and to model protest zeros.

HEALTH ECONOMICS, Issue 2 2001
Estimating the determinants of individuals' willingness to pay for home care services in day case surgery
Abstract The use of day case surgery has increased rapidly as an alternative to inpatient surgery. Little is known, however, about the value of day case surgery to patients. The aim of this paper was to develop a contingent valuation survey to investigate how individuals value the costs of shifting from inpatient to day case surgery based on home care services. Using the willingness to pay (WTP) approach, two kinds of sequential experiments are compared: the maximum likelihood recursion (MLR) method and the C-optimal sequential procedure. The goal of sequential experimentation is to find bid values that provide the maximum possible information about the parameters of the WTP distribution, especially when the sample size is small. The C-optimal sequential procedure is shown to be an improvement, in terms of the statistical precision in small samples, over the MLR method. In addition, the paper presents a double hurdle (DH) approach for modelling the determinants of individuals' WTP. Using data from a contingent valuation survey conducted in 1996 on patients selected from the Day Case Surgery Unit in a hospital in the region of Catalonia, we argue that participation in the market offered and the level of consumption, that is, people's WTP, should be treated as individual choices. The results show that income and sex are related to WTP. Also, in this study, a clear presence of starting-point bias, introduced by the bid offered, was found. It is concluded that the WTP technique is potentially useful in evaluating health care programmes, although it is important to note that the criteria used to find an optimal design (in our model to minimize the asymptotic variance of the estimator used) may be restrictive from an economic point of view. Copyright © 2001 John Wiley & Sons, Ltd. [source]

Therapy of acute hepatitis C

HEPATOLOGY, Issue S1 2002
Professor Alfredo Alberti M.D.
Acute hepatitis C has a high propensity to become chronic, which provides the rationale for treating patients with acute disease attempting to prevent chronicity. Almost all published studies on therapy of acute hepatitis C have been small in size, uncontrolled, and highly heterogeneous as to patient features, dose and duration of treatment, follow-up evaluation, and criteria used to define efficacy and safety. The published studies on treatment of acute hepatitis C have used standard alfa or beta interferon monotherapy: none have evaluated combination therapy of interferon and ribavirin or peginterferon. Several meta-analyses of published studies have concluded that initiation of interferon monotherapy during the acute phase of hepatitis C virus (HCV) infection significantly reduces (by 30% to 40%) evolution to chronic hepatitis. The tolerability of interferon in acute hepatitis C has been excellent, even in symptomatic and icteric patients; the side effects and adverse events being similar in type and frequency to those seen when treating chronic cases. Thus, currently available data support treatment of patients with acute hepatitis C, but data are insufficient to draw firm conclusions about which patients to treat, when therapy should be started, or what regimen is optimal. Future studies of adequate size and design should focus on efficacy and tolerability of peginterferons and whether therapy should be started immediately after diagnosis or delayed for 2 to 4 months to avoid treatment of patients who spontaneously recover. (HEPATOLOGY 2002;36:S195-S200). [source]

Extraction of Stimulus-Selective Intrinsic Optical Signals From the Cat Visual Cortex

IEEJ TRANSACTIONS ON ELECTRICAL AND ELECTRONIC ENGINEERING, Issue 6 2009
Midori Nagai Non-member
Abstract Optical imaging based on intrinsic optical signals has been widely utilized in studies on the functional organization of various areas of the brain. Because of the small size of the optical signals and the large amount of background noise that is present, it is critical to be able to separate the stimulus-driven optical change from the background. In this study, we propose a novel method and apply it to the analysis of the orientation preference structure in cat area 17. The three criteria used to determine the activation included the amplitude of the optical change in the optical intensity, the statistical significance level of the change, and the temporal relationship between the optical change and the visual stimulation. In the activated region extracted by the new method, 82.4 ± 8.2% of the cells were electrophysiologically responsive to the stimuli that evoked the optical change. This was significantly higher than the 46.4 ± 7.1% value obtained when the activation region was extracted by the most widely used method, i.e. a differential map between two complementary stimuli, such as orthogonal orientations. Our newly proposed method provides a robust and an effective way to reduce manual operations used in the signal extraction process. Copyright © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. [source]

Wobbles, humps and sudden jumps: a case study of continuity, discontinuity and variability in early language development

INFANT AND CHILD DEVELOPMENT, Issue 1 2007
Marijn van Dijk
Abstract Current individual-based, process-oriented approaches (dynamic systems theory and the microgenetic perspective) have led to an increase of variability-centred studies in the literature. The aim of this article is to propose a technique that incorporates variability in the analysis of the shape of developmental change. This approach is illustrated by the analysis of time serial language data, in particular data on the development of preposition use, collected from four participants. Visual inspection suggests that the development of prepositions-in-contexts shows a characteristic pattern of two phases, corresponding with a discontinuity. Three criteria for testing such discontinuous phase-wise change in individual data are presented and applied to the data. These are: (1) the sub-pattern criterion, (2) the peak criterion and (3) the membership criterion. The analyses rely on bootstrap and resampling procedures based on various null hypotheses. The results show that there are some indications of discontinuity in all participants, although clear inter-individual differences have been found, depending on the criteria used. In the discussion we will address several fundamental issues concerning (dis)continuity and variability in individual-based, process-oriented data sets. Copyright © 2007 John Wiley & Sons, Ltd. [source]

Sediment quality assessment and dredged material management in Spain: Part II, analysis of action levels for dredged material management and application to the bay of Cádiz,

INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, Issue 4 2007
Manuel Alvarez-Guerra
Abstract When sediments are removed from aquatic bottoms, they turn into dredged material that must be managed, taking into account its environmental impact. In Part II of this 2-part paper addressing sediment quality assessment and dredged material management in Spain, legislation and criteria used to regulate dredged material disposal at sea in different European countries are reviewed, as are action levels (ALs) derived by different countries used to evaluate management of dredged sediments from Cádiz Bay located on the South Atlantic coast of Spain. Comparison of ALs established for dredged material disposal by different countries reveals orders of magnitude differences in the values established for the same chemical. In Part I of this 2-part paper, review of different sediment quality guideline (SQG) methods used to support sediment quality assessments indicated a great heterogeneity of SQGs, both with regard to the numeric values for a particular chemical and the number of substances for which SQGs have been derived. The analysis highlighted the absence of SQGs for priority substances identified in current European Union water policy. Here, in Part II, the ALs are applied to dredged sediments from Cádiz Bay (South Atlantic coast of Spain), evidencing that the heterogeneity of ALs implemented in the reviewed countries could determine different management strategies. The application of other measurements such as bioassays might offer information useful in identifying a cost-effective management option in a decision-making framework, especially for dredged material with intermediate chemical concentrations. [source]

Evaluation of criteria used to assess the quality of aquatic toxicity data

INTEGRATED ENVIRONMENTAL ASSESSMENT AND MANAGEMENT, Issue 3 2005
Dustin A. Hobbs
Abstract Good quality toxicity data underpins robust hazard and risk assessments in aquatic systems and the derivation of water quality guidelines for ecosystems. Hence, an objective scheme to assess the quality of toxicity data forms an important part of this process. The variation of scores from 2 research papers using the Australasian ecotoxicity database (AED) quality assessment scheme was evaluated by 23 ecotoxicologists. The results showed that the quality class that the assessors gave each paper varied by less than 10% when compared with a quality score agreed a priori between the authors of this study. It was determined that the majority of the variation in each assessment was due to ambiguous or poorly written assessment criteria, information that was difficult to find, or information in the paper that was overlooked by the assessor. This led to refinements of the assessment criteria in the AED, which resulted in a 16% improvement (i.e., reduction) in the mean variation of scores for the 2 papers when compared with the a priori scores. The improvement in consensus among different assessors evaluating the same research papers suggests that the data quality assessment scheme proposed in this article provides a more robust scheme for assessing the quality of aquatic toxicity data than methods currently available. [source]

The Role and Functions of Audit Committees in the Indian Corporate Governance: Empirical Findings

INTERNATIONAL JOURNAL OF AUDITING, Issue 1 2004
Jawaher Al-Mudhaki
This paper examines the composition, focus and functions of audit committees (ACs), the effects of meetings and the criteria used in the selection of members by Indian listed companies from 73 questionnaire responses. The survey was carried out during February,March, 2002. The study reveals that so far only 56.2% of companies have established an AC despite the fact that it is now mandatory. Of those companies which have ACs, 68.3% have between three and six members on ACs. However, only 14.6% of companies have independent non-executive directors on the committee, while 90.2% have non-executive directors. This shows a lack of independent representation on the committees. The functions of ACs are quite diverse and are classified in three areas: financial statements and reporting, audit planning, and internal control and evaluation. The review of annual audited financial statements, discussion and recommendations of audit fees and review of the effectiveness of internal control were rated very highly by the respondents. The review of note disclosure and scope of external audit work are other important functions performed by ACs. The most important areas for focus are compliance with the standards and regulatory bodies, probing material items and undisclosed liabilities. However, there are statistical differences between medium and large sized companies in the performance of their role. The main criteria used for membership of an AC are: experience and knowledge of business, experience of holding similar positions and accounting and finance expertise. Ownership in the company was not perceived as an important criterion. The majority of companies' AC meetings are held monthly or quarterly. MANOVA analysis reveals that the frequency of AC meetings has an effect on the internal control functions. The study concludes that the concept of an AC is not new in India but their formation is slow and their composition lacks independence. AC functions are still concentrated in the traditional areas of accounting and their role is not changing fast enough to make the corporate governance more effective. [source]

Diagnostic criteria in patients with complex regional pain syndrome assessed in an out-patient clinic

ACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 7 2010
E. A. M. VAN BODEGRAVEN HOF
Background: Specific criteria have been described and accepted worldwide for diagnosing patients with complex regional pain syndrome (CRPS). Nevertheless, a clear-cut diagnosis cannot be confirmed in a number of cases. Aim: The objective of this study was to investigate the effectiveness of the described diagnostic criteria used by several clinical disciplines. Methods: We included 195 patients who were referred to our pain clinic within a period of 1 year. Data were collected on patient characteristics, signs, symptoms, disease-related medication, and the background of the referring clinicians. Results: The Harden and Bruehl criteria were confirmed in 95 patients (49%). These patients used a higher than average number of analgesics, opiates, and anti-oxidants, and frequently received prescriptions for benzodiazepines instead of anti-depressants. The mean disease duration was 29 ± 4.6 months and the mean visual analogue score for pain was 8.1 ± 0.19. A subgroup of patients had a colder temperature in the affected extremity compared with the unaffected extremity. This subgroup showed a longer disease duration and higher visual analogue scale pain. Conclusion: The diagnostic criteria used to determine CRPS should be further improved. A large number of referred patients experienced substantial pain, without receiving adequate medication. Disease-related medication is unrelated to CRPS-specific disease activity. Knowledge of underlying mechanisms is warranted before an adequate pharmaceutical intervention can be considered. [source]

ARCHSECRET: a multi-item scale to measure service quality within the voluntary sector

INTERNATIONAL JOURNAL OF NONPROFIT & VOLUNTARY SECTOR MARKETING, Issue 2 2001
Liz Vaughan
This paper provides an overview of the application of SERVQUAL reflecting the theoretical criticisms concerning disconfirmation model, process orientation, role of expectations and portability. The original SERVQUAL framework was found to be inappropriate for services that had no close analogue with the private sector. A qualitative research study was undertaken to establish the sector-specific criteria used by customers to evaluate service quality. The study identified 40 potentially unique features of the service as perceived by service recipients. These features were developed into a pilot survey instrument that comprised 40 questions, covering expectations, perceptions and importance. A pilot study was undertaken to test the instrument among disabled customers and their carers across the main centres of a national voluntary organisation. Analyses of the pilot survey data resulted in a set of 27 distinct statements across ten hypothesised service quality dimensions. These are Access, Responsiveness, Communication, Humaneness, Security, Enabling/Empowerment, Competence, Reliability, Equity, and Tangibles, giving rise to the acronym ARCHSECRET. The ARCHSECRET instrument is potentially a powerful diagnostic tool for managers in their pursuit of continuous quality improvement within voluntary sector organisations. Copyright © 2001 Henry Stewart Publications [source]

Examining criteria for identifying and differentiating fossil faunal assemblages accumulated by hyenas and hominins using extant hyenid accumulations

INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 1 2010
B. F. Kuhn
Abstract Numerous authors have put forth criteria for distinguishing between assemblages collected by hyenas and hominins. Of the seven most recognised criteria used to distinguish hyenid from hominin assemblages, it has recently been suggested that four be rejected and three retained. The four rejected criteria are: an excessive proportion of horns and horn cores in hyena accumulated assemblages; the absence of small, hard, compact bones; mortality profiles; and the ratio of cranial bones to postcranial bones. The three criteria previous researchers suggested be retained are: a carnivore MNI ratio of ,20%; an abundance of cylinder fragments; and hyena-inflicted damage upon the bones. In this examination of over 27,000 faunal remains associated with all three species of extant bone-collecting hyenids from four countries and two continents, six of the seven previously established criteria and reconsiderations of criteria have been evaluated. The results of the present study indicate that of the six criteria examined, none, as written, are indicative of hyenid activity on bone assemblages of unknown origin. Copyright © 2008 John Wiley & Sons, Ltd. [source]

Nursing Home Practitioner Survey of Diagnostic Criteria for Urinary Tract Infections

JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 11 2005
Manisha Juthani-Mehta MD
Objectives: To identify clinical and laboratory criteria used by nursing home practitioners for diagnosis and treatment of urinary tract infections (UTIs) in nursing home residents. To determine practitioner knowledge of the most commonly used consensus criteria (i.e., McGeer criteria) for UTIs. Design: Self-administered survey. Setting: Three New Haven,area nursing homes. Participants: Physicians (n=25), physician assistants (PAs, n=3), directors/assistant directors of nursing (n=8), charge nurses (n=37), and infection control practitioners (n=3). Measurements: Open- and closed-ended questions. Results: Nineteen physicians, three PAs, and 41 nurses completed 63 of 76 (83%) surveys. The five most commonly reported triggers for suspecting UTI in noncatheterized residents were change in mental status (57/63, 90%), fever (48/63, 76%), change in voiding pattern (44/63, 70%), dysuria (41/63, 65%), and change in character of urine (37/63, 59%). Asked to identify their first diagnostic step in the evaluation of UTIs, 48% (30/63) said urinary dipstick analysis, and 40% (25/63) said urinalysis and urine culture. Fourteen of 22 (64%) physicians and PAs versus 40 of 40 (100%) nurses were aware of the McGeer criteria for noncatheterized patients (P<.001); 12 of 22 (55%) physicians and PAs versus 38 of 39 (97%) nurses used them in clinical practice (P<.001). Conclusion: Although surveillance and treatment consensus criteria have been developed, there are no universally accepted diagnostic criteria. This survey demonstrated a distinction between surveillance criteria and criteria practitioners used in clinical practice. Prospective data are needed to develop evidence-based clinical and laboratory criteria of UTIs in nursing home residents that can be used to identify prospectively tested treatment and prevention strategies. [source]