Cost-effective Option (cost-effective + option)

Distribution by Scientific Domains


Selected Abstracts


An economic evaluation of different sinus lift techniques

JOURNAL OF CLINICAL PERIODONTOLOGY, Issue 8 2010
Stefan Listl
Listl S, Faggion CM. An economic evaluation of different sinus lift techniques. J Clin Periodontol 2010; 37: 777-787 doi: 10.1111/j.1600-051X.2010.01577.x. Abstract Purpose: To identify the most cost-effective approach to sinus lifting on the basis of currently available evidence. Methods: We incorporate the costs and clinical outcomes of nine different sinus lift techniques within a decision tree model in which costs are based on insurance regulations in Germany and health outcomes follow two recent meta-analyses. The most cost-effective treatment option is identified on the basis of the maximum net benefit criterion. Uncertainties regarding health outcomes are incorporated via probabilistic sensitivity analysis based on Monte-Carlo simulation. Results: When there are no financial restrictions, the optimum treatment strategy is the lateral approach with autogenous particulate bone and a resorbable membrane. When, however, monetary resources for sinus-floor elevation are scarce, the most cost-effective option is the transalveolar technique without bone grafting. Only if relatively high costs can be afforded or if initial bone height at implant site is below 5 mm is the maximum net benefit achieved by lateral approaches. Conclusions: On the basis of currently available evidence, the transalveolar technique is advisable when monetary resources for sinus-floor elevation are scarce and initial bone height is sufficiently high. Lateral approaches are primarily recommended for lower pre-operative bone heights. [source]


An assessment of re-randomization methods in bark beetle (Scolytidae) trapping bioassays

AGRICULTURAL AND FOREST ENTOMOLOGY, Issue 4 2006
Christopher J. Fettig
Abstract 1,Numerous studies have explored the role of semiochemicals in the behaviour of bark beetles (Scolytidae). 2,Multiple-funnel traps are often used to elucidate these behavioural responses. Sufficient sample sizes are obtained by using large numbers of traps to which treatments are randomly assigned once, or by frequent collection of trap catches and subsequent re-randomization of treatments. 3,Recently, there has been some debate about the potential for trap contamination to occur when semiochemical treatments (baits), and not trap-treatment units (traps and baits), are re-randomized among existing traps. Due to the volatility of many semiochemicals, small levels of contamination could potentially confound results. 4,A literature survey was conducted to determine the frequency of re-randomizing semiochemical treatments (baits) vs. trap-treatment units (traps and baits) in scolytid trapping bioassays. An experiment was then conducted to determine whether differences in the response of Dendroctonus brevicomis LeConte to attractant-baited traps exist between the two methods. 5,The majority of papers examined reported use of a large number of fixed replicates (traps) rather than re-randomization of treatments at frequent intervals. Seventy-five percent of papers for which re-randomization methods could be determined reported relocation of semiochemical treatments (baits) only. 6,No significant differences in trap catch were observed among multiple-funnel traps aged with D. brevcomis baits (Phero Tech Inc., Canada) for 0, 30 and 90 days, suggesting that contamination did not influence the results. 7,It is concluded that re-randomizing baits is a viable cost-effective option to re-randomizing trap and bait units. [source]


Prophylactic strategies for hepatitis B patients undergoing liver transplant: A cost-effectiveness analysis

LIVER TRANSPLANTATION, Issue 5 2006
Yock Young Dan
Hepatitis B immunoglobulin with lamivudine prophylaxis (LAM/HBIG) is effective in preventing Hepatitis B (HBV) recurrence posttransplant but is expensive and inconvenient. Lamivudine-resistant HBV, which has limited the usefulness of lamivudine monoprophylaxis in transplant, can now be effectively controlled with adefovir dipivoxil. We performed a cost-effectiveness analysis on the strategies of lamivudine prophylaxis with adefovir rescue(LAM/ADV) compared to combination LAM/intravenous fixed high-dose HBIG prophylaxis(LAM/ivHBIG) or LAM/intramuscular HBIG prophylaxis(LAM/imHBIG). Markov modeling was performed with analysis from societal perspective. Probability rates were derived from systematic review of the literature and cost taken from MEDICARE database. Outcome measures were incremental cost-effectiveness ratio(ICER) and cost to prevent each HBV recurrence and death. Analysis was performed at 5 years posttransplant as well as at end of life expectancy (15 years). Combination LAM/ivHBIG cost an additional USD562,000 at 15 years, while LAM/imHBIG cost an additional USD139,000 per patient compared to LAM/ADV. Although there is an estimated increase in recurrence of 53% with LAM/ADV and 7.6% increased mortality at the end of life expectancy (15 years), the ICER of LAM/ivHBIG over LAM/ADV treatment is USD760,000 per quality-adjusted life-years and for LAM/imHBIG, USD188,000. Cost-effectiveness is most sensitive to cost of HBIG. Lamivudine prophylaxis with adefovir dipivoxil salvage offers the more cost-effective option for HBV patients undergoing liver transplant but with higher recurrence and death rate using a model that favors LAM/HBIG. Lowering the cost of HBIG maintenance will improve cost-effectiveness of LAM/HBIG strategy. In conclusion, a tailored approach based on individual risks will optimize the cost-benefit of HBV transplant prophylaxis. Liver Transpl 12:736,746, 2006. © 2006 AASLD. [source]


The Cogeneration Potential of the Sugar Industry in Vietnam

OPEC ENERGY REVIEW, Issue 1 2004
Subhes C. Bhattacharyya
Vietnam produces about 15 million tons of sugarcane per year and about five mt of bagasse. There is the potential for cogeneration using bagasse, which can also help overcome power shortages in the country. This paper analyses the potential for cogeneration from the sugar industry in Vietnam under three different scenarios and finds that between 100 and 300 megawatts of power-generating capacity could be supported by the bagasse generated from sugar mills, depending on the technology considered for sugar mills and cogeneration and the possibility of renovation of the existing mills. The paper also assesses the expense of cogeneration and finds it to be a cost-effective option for all types of sugar mill. It is found that the cost savings from cogeneration would more than offset the cost of introducing cogeneration in sugar mills with inefficient caneprocessing technologies. Sugar mills with modern technologies would have a significant amount of excess power and most of these plants would break-even if they sold excess power at around 4.5 cents per kilowatt hour. The break-even cost and the average production cost are sensitive to the investment cost assumptions. The paper thus suggests that cogeneration from the sugar industry is an attractive option for investors in existing mills or new sugar mills alike. [source]


Evapotranspiration covers: An innovative approach to remediate and close contaminated sites

REMEDIATION, Issue 1 2003
Kelly L. Madalinski
A new, cost-effective option for the remediation and final closure of contaminated landfill sites gaining interest among environmental professionals is the evapotranspiration (ET) cover. Unlike current covers that use hydraulic barriers to prevent water from reaching the waste, ET covers rely on the simple concept of using water balance components to meet this goal. Depending on site conditions and other factors, ET covers may be less costly to construct, while still offering performance equivalent to conventional covers. While ET covers are being proposed, tested, or installed at a number of contaminated sites, field performance data remain limited. To address the need for more information, the U.S. Environmental Protection Agency (EPA) has been conducting several efforts to make available more information about this promising alternative solution. This article summarizes these efforts and provides information on the current status of using ET covers at contaminated sites. © 2003 Wiley Periodicals, Inc. [source]


Cost-effectiveness of interventions to prevent alcohol-related disease and injury in Australia

ADDICTION, Issue 10 2009
Linda Cobiac
ABSTRACT Aims To evaluate cost-effectiveness of eight interventions for reducing alcohol-attributable harm and determine the optimal intervention mix. Methods Interventions include volumetric taxation, advertising bans, an increase in minimum legal drinking age, licensing controls on operating hours, brief intervention (with and without general practitioner telemarketing and support), drink driving campaigns, random breath testing and residential treatment for alcohol dependence (with and without naltrexone). Cost-effectiveness is modelled over the life-time of the Australian population in 2003, with all costs and health outcomes evaluated from an Australian health sector perspective. Each intervention is compared with current practice, and the most cost-effective options are then combined to determine the optimal intervention mix. Measurements Cost-effectiveness is measured in 2003 Australian dollars per disability adjusted life year averted. Findings Although current alcohol intervention in Australia (random breath testing) is cost-effective, if the current spending of $71 million could be invested in a more cost-effective combination of interventions, more than 10 times the amount of health gain could be achieved. Taken as a package of interventions, all seven preventive interventions would be a cost-effective investment that could lead to substantial improvement in population health; only residential treatment is not cost-effective. Conclusions Based on current evidence, interventions to reduce harm from alcohol are highly recommended. The potential reduction in costs of treating alcohol-related diseases and injuries mean that substantial improvements in population health can be achieved at a relatively low cost to the health sector. [source]