Control Options (control + option)

Distribution by Scientific Domains


Selected Abstracts


The ecological challenge of immunocontraception: editor's introduction

JOURNAL OF APPLIED ECOLOGY, Issue 6 2000
N.D. Barlow
Summary 1. ,The problems of vertebrate pests are greater now than ever before, with vertebrate control constrained by problems of humaneness, scale and environmental impact. However, immunocontraception involves a conceptually ideal solution. Although not intrinsically novel, its delivery in baits or by a self-spreading vector and its effectiveness in pest control, are now the focus of growing international interest. 2. ,Major ecological questions correspond to the two forms of delivery: baits and vectors. First, given an effective immunocontraceptive, inserted into a bait and eaten by a pest, would the resulting level of sterilization in the population effectively suppress densities? Secondly, given that the immunocontraceptive agent can be inserted into a microparasitic or macroparasitic infective vector, would the modified vector persist at sufficient prevalence in the host population, and hence suppress densities to the required extent? 3. ,The papers published in this Special Profile focus on behaviour following sterilization or they model the likely impact of viral-vectored immunocontraception. They highlight advantages and disadvantages of immunocontraception and some general, novel and specific issues. These include the possibility of behaviourally mediated population responses to fertility control; the possible advantages of a mixed baiting and vector strategy; the competitiveness of a modified vector; the appropriateness of immunocontraception for controlling invasive vertebrates on islands; and the need for a ,pay-off' methodology for assessing genetic modifications against alternatives. 4. ,The findings offer significant benefits for management and policy: they will inform decisions on whether to pursue immunocontraception as a control option, and they provide evidence about efficacy and risk in applications to release genetically modified vectors. 5. ,Although many of the problems in developing immunocontraception technology are biotechnological, questions about the effectiveness of immunocontraceptive pest control are ultimately in the domain of ecologists. [source]


NuvaRing: new combined hormonal contraceptive device

PRESCRIBER, Issue 12 2009
MRPharmS, Steve Chaplin MSc
NuvaRing is a new contraceptive device that delivers ethinylestradiol and etonogestrel and is inserted once every cycle for three weeks. In our New products review, Steve Chaplin presents the clinical data relating to its efficacy and adverse effects and Dr Tina Peers comments on its place as a birth control option. Copyright © 2009 Wiley Interface Ltd [source]


Variant Creutzfeldt-Jakob disease: An unfolding epidemic of misfolded proteins

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 6 2002
P Horby
Abstract: Variant Creutzfeldt-Jakob disease (vCJD) is an emerging infectious disease believed to be the human manifestation of bovine spongiform encephalopathy (BSE). Variant CJD belongs to a family of human and animal diseases called transmissible spongiform encephalopathies (TSE). The pathogenesis of TSE is not fully understood, but a modified form of a normal cellular protein plays a central role. Current measures to control vCJD aim to prevent transmission of the infectious agent from animals to humans through food or pharmaceutical products and to prevent transmission from person to person via medical interventions. The anticipated development of preclinical diagnostic tests and treatments for vCJD will create new control options and difficult choices. [source]


Control techniques for Culicoides biting midges and their application in the U.K. and northwestern Palaearctic

MEDICAL AND VETERINARY ENTOMOLOGY, Issue 3 2008
S. CARPENTER
Abstract The recent emergence of bluetongue virus (Reoviridae: Orbivirus) (BTV) in northern Europe, for the first time in recorded history, has led to an urgent need for methods to control the disease caused by this virus and the midges that spread it. This paper reviews various methods of vector control that have been employed elsewhere and assesses their likely efficacy for controlling vectors of BTV in northern Europe. Methods of controlling Culicoides spp. (Diptera: Ceratopogonidae) have included: (a) application of insecticides and pathogens to habitats where larvae develop; (b) environmental interventions to remove larval breeding sites; (c) controlling adult midges by treating either resting sites, such as animal housing, or host animals with insecticides; (d) housing livestock in screened buildings, and (e) using repellents or host kairomones to lure and kill adult midges. The major vectors of BTV in northern Europe are species from the Culicoides obsoletus (Meigen) and Culicoides pulicaris (L.) groups, for which there are scant data on breeding habits, resting behaviour and host-oriented responses. Consequently, there is little information on which to base a rational strategy for controlling midges or for predicting the likely impact of interventions. However, data extrapolated from the results of vector control operations conducted elsewhere, combined with some assessment of how acceptable or not different methods may be within northern Europe, indicate that the treatment of livestock and animal housing with pyrethroids, the use of midge-proofed stabling for viraemic or high-value animals and the promotion of good farm practice to at least partially eliminate local breeding sites are the best options currently available. Research to assess and improve the efficacy of these methods is required and, in the longer term, efforts should be made to develop better bait systems for monitoring and, possibly, controlling midges. All these studies will need better methods of analysing the ecology and behaviour of midges in the field than are currently in use. The paucity of control options and basic knowledge serve to warn us that we must be better prepared for the possible emergence of other midge-borne diseases, particularly African horse sickness. [source]


Towards a fuller understanding of mosquito behaviour: use of electrocuting grids to compare the odour-orientated responses of Anopheles arabiensis and An. quadriannulatus in the field

MEDICAL AND VETERINARY ENTOMOLOGY, Issue 2 2008
S. J. TORR
Abstract The epidemiological role of and control options for any mosquito species depend on its degree of ,anthropophily'. However, the behavioural basis of this term is poorly understood. Accordingly, studies in Zimbabwe quantified the effects of natural odours from cattle and humans, and synthetic components of these odours, on the attraction, entry and landing responses of Anopheles arabiensis Giles (Diptera: Culicidae) and Anopheles quadriannulatus Theobald. The numbers of mosquitoes attracted to human or cattle odour were compared using electrocuting nets (E-nets), and entry responses were gauged by the catch from an odour-baited entry trap (OBET) relative to that from an odour-baited E-net. Landing responses were estimated by comparing the catches from E-nets and cloth targets covered with an electrocuting grid. For An. arabiensis, E-nets baited with odour from a single ox or a single man caught similar numbers, and increasing the dose of human odour from one to three men increased the catch four-fold. For An. quadriannulatus, catches from E-nets increased up to six-fold in the progression: man, three men, ox, and man + ox, with catch being correlated with bait mass. Entry responses of An. arabiensis were stronger with human odour (entry response 62%) than with ox odour (6%) or a mixture of cattle and human odours (15%). For An. quadriannulatus, the entry response was low (< 2%) with both cattle and human odour. Anopheles arabiensis did not exhibit a strong entry response to carbon dioxide (CO2) (0.2,2 L/min). The trends observed using OBETs and E-nets also applied to mosquitoes approaching and entering a hut. Catches from an electrocuting target baited with either CO2 or a blend of acetone, 1-octen-3-ol, 4-methylphenol and 3-n-propylphenol , components of natural ox odour , showed that virtually all mosquitoes arriving there alighted on it. The propensity of An. arabiensis to enter human habitation seemed to be mediated by odours other than CO2 alone. Characterizing ,anthropophily' by comparing the numbers of mosquitoes caught by traps baited with different host odours can lead to spurious conclusions; OBETs baited with human odour caught around two to four times more An. arabiensis than cattle-baited OBETs, whereas a human-baited E-net caught less (, 0.7) An. arabiensis than a cattle-baited E-net. Similar caution is warranted for other species of mosquito vectors. A fuller understanding of how to exploit mosquito behaviour for control and surveys requires wider approaches and more use of appropriate tools. [source]