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Conscious
Terms modified by Conscious Selected AbstractsOn Historicized Meanings and Being Conscious about one's own Theoretical Premises,A Basis for a Renewed Dialogue between History and Philosophy of Education?EDUCATIONAL PHILOSOPHY AND THEORY, Issue 1 2007Marc Depaepe First page of article [source] An assessment of consumer preference for fair trade coffee in Toronto and VancouverAGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 2 2010John Cranfield In this article, the authors use conjoint analysis to elicit the views of coffee consumers on the attributes of Fair Trade coffee using data from the Greater Toronto Area and Vancouver collected through face-to-face interviews with consumers. The impact of socioeconomic and demographic factors on respondents' acceptance of Fair Trade coffee is evaluated using cluster analysis and multinomial logit models. The results suggest that, regardless of location, consumers place a strong premium on price and labeling claims. Three consumer segments are identified in each city; in Toronto, these segments are labeled Fair Trade-Focused, Price Conscious, and Balanced Buyers; for Vancouver these segments are labeled Organic and Fair Trade-Focused, Price Conscious, and Balanced Buyers. Although a broad spectrum of variables influences segment membership, no single variable explains membership in the same segment in each city. Such a result is rather telling; it suggests deeper constructs underlie segment membership, and presumably consumption behavior with respect to Fair Trade coffee. © 2010 Wiley Periodicals, Inc. [source] A Conscious and Inclusive Family StudiesJOURNAL OF MARRIAGE AND FAMILY, Issue 1 2000Katherine R. Allen I argue that family scholars must take bolder steps to engage the tensions between our heritage of positivist science and its postmodern challenges. I also argue that constructing theories, utilizing research methods, and examining substantive issues should be relevant to the diversity of the families we study and to ourselves as members of families. I offer examples of developing an informed reflexive consciousness to broaden the rationalist foundation that dominates family scholarship. For a more inclusive, balanced, and invigorated family studies, our subjective experiences and commitments as researchers should be acknowledged, confronted, and integrated. A family studies that is responsible to our readers, students, selves, and the people whose lives we study requires that we engage the critical intersections of race, class, gender, sexual orientation, and age as they define family diversity. [source] Pharmacodynamics of Carvedilol in Conscious, Healthy DogsJOURNAL OF VETERINARY INTERNAL MEDICINE, Issue 2 2006Sonya G. Gordon The purpose of the study reported here was to determine the magnitude and duration of beta-blocking efficacy, determine an effective dose and dosing interval, and document safety and tolerability of carvedilol given orally in clinically normal dogs. Pharmacodynamic data were evaluated in conscious, unrestrained, healthy hound dogs at baseline and after long-term oral administration of carvedilol (1.5 mg/kg of body weight PO q12h for >5 days). At baseline, heart rate (HR) and blood pressure (BP) data were collected continuously for 24 hours, and complete echocardiography was performed. This protocol was repeated after long-term oral carvedilol administration. Additionally, isoproterenol was administered to evaluate the magnitude and duration of the nonselective beta-blocking efficacy of carvedilol. An isoproterenol challenge was performed 0.75, 1.5, 2.25, 4, 6, 12, and 24 hours after carvedilol administration, with echocardiography being performed once at 2 hours. Plasma samples were obtained prior to each challenge time point for determination of plasma carvedilol concentration. Time series regression analysis indicated no difference between baseline and carvedilol-induced HR or BP trend lines in 6 of 8 dogs. In 2 of 8 dogs, HR, after long-term carvedilol administration, was reduced. Carvedilol attenuated isoproterenol-induced changes in HR by 54,76% through 12 hours and by 30% at 24 hours. The BP changes were attenuated by 80,100% through 12 hours. These data suggest that carvedilol (1.5 mg/kg PO q12h) in healthy, conscious dogs confers nonselective beta blockade for 12 hours, with minimal effects on resting HR, BP, and echocardiographic variables. Additionally, the magnitude of beta blockade correlated strongly to peak plasma carvedilol concentration, suggesting that therapeutic drug monitoring may be clinically useful. [source] Are Spirituality and Religiosity Resources for Patients with Chronic Pain Conditions?PAIN MEDICINE, Issue 2 2009Arndt Büssing Prof Dr ABSTRACT Objective., We studied whether or not spirituality/religiosity is a relevant resource for patients with chronic pain conditions, and to analyze interrelations between spirituality/religiosity (SpREUK Questionnaire; SpREUK is an acronym of the German translation of "Spiritual and Religious Attitudes in Dealing with Illness"), adaptive coping styles that refer to the concept of locus of disease control (AKU Questionnaire; AKU is an acronym of the German translation of "Adaptive Coping with Disease"), life satisfaction, and appraisal dimensions. Patients., In a multicenter cross-sectional study, 580 patients with chronic pain conditions were enrolled. Results., We found that the patients relied on both external powerful sources of disease control and on internal powers and virtues, while Trust in Higher Source (intrinsic religiosity) or Illness as Chance (reappraisal) were valued moderately; Search for Meaningful Support/Access (spiritual quest orientation) was of minor relevance. Stepwise regression analyses revealed that the internal sources of disease control, such as Conscious and Healthy Way of Living and Positive Attitudes, were (apart from the religious denomination) the strongest predictors of patients' reliance on spirituality/religiosity. Both behavioral styles were rated significantly lower in patients who regarded themselves as neither religious nor spiritual. Positive disease interpretations such as Challenge and Value were clearly associated with a spiritual quest orientation and intrinsic religiosity. Conclusion., The associations between spirituality/religiosity, positive appraisals. and internal adaptive coping strategies indicate that the utilization of spirituality/religiosity goes far beyond fatalistic acceptance, but can be regarded as an active coping process. The findings support the need for further research concerning the contributions of spiritual coping in adjustment to chronic pain. [source] Neuro-Cognitive Mechanisms of Conscious and Unconscious Visual PerceptionPSYCHOPHYSIOLOGY, Issue 2009Article first published online: 11 SEP 200 No abstract is available for this article. [source] Temporal changes in the involvement of pyruvate dehydrogenase complex in muscle lactate accumulation during lipopolysaccharide infusion in ratsTHE JOURNAL OF PHYSIOLOGY, Issue 6 2008N. Alamdari A characteristic manifestation of sepsis is muscle lactate accumulation. This study examined any putative (causative) association between pyruvate dehydrogenase complex (PDC) inhibition and lactate accumulation in the extensor digitorum longus (EDL) muscle of rats infused with lipopolysaccharide (LPS), and explored the involvement of increased transcription of muscle-specific pyruvate dehydrogenase kinase (PDK) isoenzymes. Conscious, male Sprague,Dawley rats were infused i.v. with saline (0.4 ml h,1, control) or LPS (150 ,g kg,1 h,1) for 2 h, 6 h or 24 h (n= 6,8). Muscle lactate concentration was elevated after 2, 6 and 24 h LPS infusion. Muscle PDC activity was the same at 2 h and 6 h, but was 65% lower after 24 h of LPS infusion (P < 0.01), when there was a 47% decrease in acetylcarnitine concentration (P < 0.05), and a 24-fold increase in PDK4 mRNA expression (P < 0.001). These changes were preceded by marked increases in tumour necrosis factor-, and interleukin-6 mRNA expression at 2 h. The findings indicate that the early (2 and 6 h) elevation in muscle lactate concentration during LPS infusion was not attributable to limited muscle oxygen availability or ATP production (evidenced by unchanged ATP and phosphocreatine (PCr) concentrations) or to PDC inhibition, whereas after 24 h, muscle lactate accumulation appears to have resulted from PDC activation status limiting pyruvate flux, most probably due to cytokine-mediated up-regulation of PDK4 transcription. [source] The Interplay between Conscious and Automatic Self-Regulation and Adolescents' Physical Activity: The Role of Planning, Intentions, and Lack of AwarenessAPPLIED PSYCHOLOGY, Issue 2 2009Stephan Dombrowski This study investigated the interplay between conscious and automatic self-regulatory variables and adolescents' physical activity. It was hypothesised that intention, planning, and lack of awareness would predict adolescents' behaviour. One hundred and fifty-five individuals (aged 13 to 17 years) completed questionnaires in two waves (with a time gap of 10 days). The results of cross-lagged panel analysis suggested that both past behaviour and planning predicted physical activity at follow-up, whereas physical activity predicted intention. Although lack of awareness, a facet of automatic processes, was negatively related to physical activity, the nested model comparison analysis indicated that the relation between lack of awareness and physical activity might be negligible. Among the self-regulatory processes, planning was found to be the most important predictor of adolescents' physical activity, although past behaviour remained the strongest predictor of future behaviour. Cette recherche porte sur l'interaction entre les variables autorégulatrices conscientes et automatiques et l'activité physique des adolescents. On a fait l'hypothèse que l'intention, la planification et l'absence de prise de conscience allaient prédire le comportement des adolescents. 155 individus âgés de 13 à 17 ans ont rempli des questionnaires en deux temps avec un intervalle de dix jours. Les résultats d'une analyse en panel retardé croisé montrent que la conduite antérieure et la planification prédisent l'activité physique qui s'ensuit alors que l'activité physique prédit l'intention. Bien que le manque de prise de conscience, une facette des processus automatiques, soit négativement corréléà l'activité physique, l'analyse de variance indique que la relation entre l'absence de prise de conscience et l'activité physique pourrait être négligeable. Des différents processus d'autorégulation, c'est la planification qui est apparue comme étant le prédicteur majeur de l'activité physique des adolescents, bien que la conduite passée reste le prédicteur le plus fiable du comportement à venir. [source] Central Bromocriptine-Induced Tachycardia is Reversed to Bradycardia in Conscious, Deoxycorticosterone Acetate-Salt Hypertensive RatsBASIC AND CLINICAL PHARMACOLOGY & TOXICOLOGY, Issue 5 2001Saad Lahlou The present study investigated the effect of bromocriptine on heart rate and the principal site of action of this agonist in conscious, deoxycorticosterone acetate-salt hypertensive rats, in which altered central dopaminergic activity has been previously reported. Intravenous administration of bromocriptine (150 ,g/kg) increased heart rate (49±5 beats/min.) in uninephrectomized control rats, while it induced a significant bradycardia (50±6 beats/min.) in deoxycorticosterone acetate-salt hypertensive rats. In the latter animals, intravenous (500 ,g/kg) or intrathecal (40 ,g/rat at T9,T10) pretreatment with domperidone, a selective dopamine D2 receptor antagonist that does not cross the blood-brain barrier, reduced partially, but significantly, the bradycardiac responses to bromocriptine (reduction of about 44% and 48% of the maximal effect, respectively). In contrast, the bromocriptine-induced bradycardia was fully abolished by intravenous pretreatment with metoclopramide (300 ,g/kg), a dopamine D2 receptor antagonist that crosses the blood-brain barrier, or by combined pretreatment with intravenous and intrathecal domperidone. These results indicate that, in deoxycorticosterone acetate-salt hypertensive rats, bromocriptine decreases rather than increases heart rate, an effect that is mediated partly through a peripheral D2 dopaminergic mechanism and partly through stimulation of spinal dopamine D2 receptors. They further support the concept that, in normotensive, conscious rats, the central tachycardia of bromocriptine appears to predominate and to mask the bradycardia of this agonist at both peripheral and spinal dopamine D2 receptors. [source] Conscious or deep sedation: a questionnaire regarding the experience of parents, children and staff during small bowel biopsyACTA PAEDIATRICA, Issue 6 2003J Skoglösa Aim: The paediatric clinics of Linköping and Norrköping, Sweden, have different procedures regarding premedication and sedation during small bowel biopsy in children with suspected or diagnosed coeliac disease. In Linköping deep sedation using intravenous propofol is the method of sedation being used and parents are not present during the biopsy procedure. In Norrköping conscious sedation using intravenous midazolam is the routine and parents stay with their child throughout the whole biopsy procedure. The aim of this study was to find out whether the preprocedural and procedural differences between the clinics affected the way in which the parents and children experienced the time before and during the biopsy procedure. Methods: A questionnaire was used to ask the parents of 102 children who had undergone small bowel capsule biopsy for their opinion regarding the discomfort experienced by their children. The parents'and children's experience was also compared with that of the paediatric nurse caring for the family during the biopsy procedure, and the paediatric gastroenterologist performing the biopsy. Results: The differences regarding premedication and sedation between the two groups did not seem to affect the parents'or the children's total experience of the biopsy procedure, nor did the presence or absence of the parents throughout the biopsy procedure. As regards the sedation given, 95% of the parents did not think that their children suffered any discomfort at all. The total experience of the biopsy procedure on a five-grade scale (5 being very good, 1 being very bad) was 5 for the parents and 4 for the children in both centres. Parents and children in both centres were very satisfied with the way in which they were taken care of during their visit to the hospital. In both units there was an obvious correlation between how the paediatric nurse experienced the biopsy procedure and how the paediatric gastroenterologist did, but only a weak correlation between the experience of the parents and that of the paediatric gastroenterologist and paediatric nurse. The anxiety of the parents was similarly estimated by the paediatric gastroenterologist and the paediatric nurse in both centres. There was no correlation between their assessment and the experience reported by the parents. Conclusion: The children undergoing small bowel biopsy and their parents felt well taken care of during their visit to the two hospitals. The differences between the clinics regarding method of sedation and presence or absence of the parents did not seem to affect how the parents and children experienced the biopsy procedure. [source] Management Strategies and Improvement of Performance of Sewer NetworksCOMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 7 2007Denys Breysse Even when they are conscious about the needs of maintenance to keep the system in a good condition, they lack efficient methods and tools that may help them in taking appropriate decisions. One can say that no really satisfactory and efficient tool exists, enabling the optimization of Inspection, Maintenance, or Rehabilitation (IMR) strategies on such systems. Sewer managers and researchers have been involved for many years in the French National Research Project for Renewal of Non Man Entry Sewer System (RERAU,Réhabilitation des Réseaux d'Assainissement Urbains, in French) to improve their knowledge of these systems and the management policies. During the RERAU project, a specific action has been dedicated to the modeling of asset ageing and maintenance. A special attention has been dedicated to the description of defects and dysfunctions, to the evaluation of performances and its modeling, accounting for its various dimensions (from the point of view of the manager, of the user, of the environment,). After having defined an Index of Technical Performance (ITp), we will introduce the Index of Technical and Economic Performance (ITEp) that is a combined measure of performance (including social costs) and technical costs. This index provides an objective standard tool for managers to compare different alternatives. It is used in the article to compare some simple IMR strategies. It sets the basis of a new method for no-man entry sewer system management, enabling us to analyze the profitableness of investment in terms of both technical and economic performance. [source] Using disputants' metaphors in mediationCONFLICT RESOLUTION QUARTERLY, Issue 1 2005Thomas H. Smith This article argues that a mediator, conscious of the metaphors disputants use, aware of their implications, and skilled in their use, will hear more; be better able to reframe, disentangle, and guide communications to explore meanings; enhance self-reflection; and expand possibilities. [source] Developing a Multicultural Curriculum in a Predominantly White Teaching Context: Lessons From an African American Teacher in a Suburban English ClassroomCURRICULUM INQUIRY, Issue 4 2005H. RICHARD MILNER ABSTRACT The author sought to understand an African American English teacher's multicultural curriculum transformation and teaching in a suburban, mostly White, high school. Building on Banks's (1998) model of multicultural curriculum integration, the study focused on a context that might otherwise be ignored because there was not a large student-of-color representation in the school. The teacher in the study was operating at one of the highest levels of Banks's model, the transformational approach. Although the teacher shared characteristics with many of the Black teachers explored in the literature, there was one important difference: much of the research and theory about Black teachers and their instruction focus on Black teachers and their effectiveness in predominantly Black settings. The Black teacher in this study taught in a predominantly White teaching context. The study suggested that even teachers highly conscious of race, culture, gender, and ethnicity may find it difficult to reach the highest level of Banks's model: the social action approach. Implications of this study suggest that multicultural curricula can be well developed and received in a predominantly White setting as long as the curriculum is thoughtfully and carefully transformed. However, the study pointed out that the pervasive discourses and belief systems against multicultural education in a school can discourage highly effective curriculum transformers, and there is a great need to help critically minded teachers persevere in the face of such adversity. [source] Learning from Difference: Considerations for Schools as CommunitiesCURRICULUM INQUIRY, Issue 3 2000Carolyn M. Shields In today's highly complex and heterogeneous public schools, the current notion of schools as homogeneous communities with shared beliefs, norms, and alues is inadequate. Drawing on Barth's (1990) question of how to use ifference as a resource, I take up ideas from feminism, multiculturalism, and inclusive education to consider the development of community in schools. I argue that despite the valuable contributions of these theoretical perspectives, each lso includes the potential for increased fragmentation and polarization. As we consider how to use differences as a foundation for community, it is important ot to reify any particular perspective, thus marginalizing others and erecting new barriers. Explicitly embracing the need to identify and respect difference, being open to new ideas without taking an exclusionary position, and committing to ongoing participation in dialogical processes may help schools to develop as more authentic communities of difference. Among the dominant issues identified in today's climate of turbulent educational reform are concerns about how to restructure schools to ensure equality of student opportunity and excellence of instruction (Elmore, 1990; Lieberman, 1992; Murphy, 1991). Many proposals include modifying present leadership and governance structures, overcoming the hegemony of existing power bases, developing mechanisms for accountability, enhancing professionalism, and co-ordinating community resources. One of the suggestions frequently made to address these issues is to change from a focus on schools as organizations to a recognition of schools as communities (Barth, 1990; Fullan, 1993; Lupart & Webber, 1996; Senge, 1990). However, despite the widespread use of the metaphor of community as an alternative to the generally accepted concept of schools as rational or functional organizations, there seems to be little clarity about the concept of community, what it might look like, how it might be implemented, or what policies might sustain it. Indeed, theories about schools as communities have often drawn from Tönnies (1887/1971) concept of gemeinschaft,a concept which perhaps evokes a more homogeneous and romanticized view of the past than one which could be helpful for improving education in today's dynamic, complex, and heterogeneous context (Beck & Kratzer, 1994; Sergiovanni, 1994a). More recently, several writers (Fine et al., 1997; Furman, 1998; Shields & Seltzer, 1997) have advanced the notion of communities of otherness or difference. These authors have suggested that rather than thinking of schools as communities that exist because of a common affiliation to an established school ethos or tradition, it might be more helpful to explore an alternative concept. A school community founded on difference would be one in which the common centre would not be taken as a given but would be co-constructed from the negotiation of disparate beliefs and values as participants learn to respect, and to listen to, each other. In this concept, bonds among members are not assumed, but forged, and boundaries are not imposed but negotiated. Over the past eight years, as I have visited and worked with a large number of schools trying earnestly to address the needs of their diverse student bodies, I have become increasingly aware of the limitations of the concept of community used in the gemeinschaft sense with its emphasis on shared values, norms, and beliefs, and have begun to reflect on the question framed by Barth (1990): ,How can we make conscious, deliberate use of differences in social class, gender, age, ability, race, and interest as resources for learning?' (p. 514). In this article, I consider how learning from three of these areas of difference: gender, race, and ability, may help us to a better understanding of educational community. This article begins with some illustrations and examples from practice, moves to consider how some theoretical perspectives may illuminate them, and concludes with reflections on how the implications of the combined reflections on practice and theory might actually help to reconceptualize and to improve practice. While it draws heavily on questions and impressions which have arisen out of much of my fieldwork, it is not intended to be an empirical paper, but a conceptual one,one which promotes reflection and discussion on the concept of schools as communities of difference. The examples of life in schools taken from longitudinal research studies in which I have been involved demonstrate several common ways in which difference is dealt with in today's schools and some of the problems inherent in these approaches. Some ideas drawn from alternative perspectives then begin to address Barth's question of how to make deliberate use of diversity as a way of thinking about community. Taken together, I hope that these ideas will be helpful in creating what I have elsewhere called ,schools as communities of difference' (Shields & Seltzer, 1997). [source] Combining Economic and Conjoint Analysis to Determine Optimal Academic ServicesDECISION SCIENCES JOURNAL OF INNOVATIVE EDUCATION, Issue 1 2004Mona Whitley Howard ABSTRACT In today's era of global competition, organizations must manage their functions and activities in a manner such that they are responsive to customers' needs and can provide excellence in service to the customer while also being efficient and cost conscious. These issues are extremely common in corporate organizations, but such concerns are equally relevant in service industries, including institutions of higher education. This study is conducted at a private, undergraduate institution of higher education. We utilize focus group evaluation and conjoint analysis combined with economic analysis in the form of a newly designed preferred utility economic cost diagram to pick the ideal services that should be provided to enrolled students at the institution. The package of ideal services accounts for preferred utility expressed by students and a new methodology (preferred utility function) to balance these against financial considerations to optimize services and financial gains for a college adult education program. This combination of focus groups and mathematical techniques can be easily employed by educational institutes. [source] Design, Economic Development, and National Policy: Lessons from KoreaDESIGN MANAGEMENT REVIEW, Issue 4 2004Dong-Sung Cho In recent years, design has been a conscious and important element in Korea's growth strategy. Dong-Sung Cho reviews the impressive outcomes linked to this decision and confirms that the "design revolution" continues. Indeed, it is evolving to provide significant future opportunities not only for global competition, but also as a force for improving the quality of life within Korea itself. [source] Echocardiographic Evaluation of Ventricular Function in MiceECHOCARDIOGRAPHY, Issue 1 2007Jeffrey N. Rottman M.D. Ventricular dysfunction remains a hallmark of most cardiac disease. The mouse has become an essential model system for cardiovascular biology, and echocardiography an established tool in the study of normal and genetically altered mice. This review describes the measurement of ventricular function, most often left ventricular function, by echocardiographic methods in mice. Technical limitations related to the small size and rapid heart rate in the mouse initially argued for the performance of echocardiography under anesthesia. More recently, higher frame rates and smaller probes operating at higher frequencies have facilitated imaging of conscious mice in some, but not all, experimental protocols and conditions. Ventricular function may be qualitatively and quantitatively evaluated under both conditions. Particular detail is provided for measurement under conscious conditions, and measurement under conscious and sedated or anesthestized conditions are contrasted. Normal values for echocardiographic indices for the common C57BL/6 strain are provided. Diastolic dysfunction is a critical pathophysiologic component of many disease states, and progress in the echocardiographic evaluation of diastolic function is discussed. Finally, echocardiography exists among several competing imaging technologies, and these alternatives are compared. [source] Equine pulmonary and systemic haemodynamic responses to endothelin-1 and a selective ETA receptor antagonistEQUINE VETERINARY JOURNAL, Issue 4 2001A. E. BENAMOU Summary Based on previous in vitro studies, we hypothesised that endothelin (ET) would induce vasoconstriction in the pulmonary circululation of the horse and that this action would be mediated via ETA receptors. Pulmonary and systemic haemodynamic responses to endothelin-1 (ET-1), a potent vasoactive endogenous peptide, were investigated in 6 conscious, nonsedated horses at rest. Bolus i.v. injections of exogenous ET-1 (0.1, 0.2 and 0.4 ,g/kg bwt) caused significant increases in pulmonary (PAP) and carotid (CAP) artery pressures, with peak increases of 79% and 51% for mean PAP and CAP, respectively. The effect of ET-1 on PAP and CAP was rapid and transient for PAP (,10 min) but prolonged for CAP (up to 60 min). ET-1 significantly decreased cardiac output by up to 35% and significantly increased systemic vascular resistance (SVR) by up to 104%. Pulmonary vascular resistance (PVR) showed a trend (P>0.05) to increase with 0.2 and 0.4 ,g/kg bwt ET-1. Infusion of a selective ETA receptor antagonist (TBC11251) completely inhibited the responses to a subsequent bolus of 0.2 ,g/kg bwt ET-1. We conclude that exogenous ET-1 exerts a potent vasoconstrictive action on the pulmonary and systemic circulations of the horse. These effects appear to be mediated largely through ETA receptors in both circulations. Endothelin may play a role in hypertensive conditions in the horse. [source] Modulation of systemic and renal haemodynamics by ,-opioids in conscious lambsEXPERIMENTAL PHYSIOLOGY, Issue 5 2006Wei Qi The purpose of the present study was to determine the cardiovascular effects of the ,-opioid receptor agonist U-50488H at two stages of postnatal maturation under physiological conditions. Experiments were carried out firstly to define systemic and renal haemodynamic responses to ,-opioid receptor activation and, secondly, to determine whether these effects are altered during postnatal maturation. To investigate whether the responses to U-50488H resulted from receptor-dependent effects, responses to U-50488H were also tested in the presence of the specific ,-opioid receptor antagonist 5,-guanidinonaltrindole (GNTI). Experiments were carried out in two groups of conscious, chronically instrumented lambs aged ,1 and ,6 weeks. Mean arterial pressure, mean venous pressure and renal blood flow (RBF) were measured for 30 min before and 90 min after i.v. injection of U-50488H or vehicle. Heart rate increased in both age groups of lambs within 10 min of U-50488H administration. Mean arterial pressure decreased for 50 min following U-50488H administration at 1 week but, in contrast, increased transiently at 10 min in 6-week-old lambs, returning to control levels by 20 min. In both age groups, there was a sustained decrease in RBF following U-50488H. The aforementioned responses to U-50488H were abolished by pretreatment with GNTI. These data provide the first measurements of systemic and renal haemodynamic responses to ,-opioid receptor activation during postnatal maturation. [source] Correlation of ,-skeletal actin expression, ventricular fibrosis and heart function with the degree of pressure overload cardiac hypertrophy in ratsEXPERIMENTAL PHYSIOLOGY, Issue 3 2006Donatella Stilli We have analysed alterations of ,-skeletal actin expression and volume fraction of fibrosis in the ventricular myocardium and their functional counterpart in terms of arrhythmogenesis and haemodynamic variables, in rats with different degrees of compensated cardiac hypertrophy induced by infra-renal abdominal aortic coarctation. The following coarctation calibres were used: 1.3 (AC1.3 group), 0.7 (AC0.7) and 0.4 mm (AC0.4); age-matched rats were used as controls (C group). One month after surgery, spontaneous and sympathetic-induced ventricular arrhythmias were telemetrically recorded from conscious freely moving animals, and invasive haemodynamic measurements were performed in anaesthetized animals. After killing, subgroups of AC and C rats were used to evaluate in the left ventricle the expression and spatial distribution of ,-skeletal actin and the amount of perivascular and interstitial fibrosis. As compared with C, all AC groups exhibited higher values of systolic pressure, ventricular weight and ventricular wall thickness. AC0.7 and AC0.4 rats also showed a larger amount of fibrosis and upregulation of ,-skeletal actin expression associated with a higher vulnerability to ventricular arrhythmias (AC0.7 and AC0.4) and enhanced myocardial contractility (AC0.4). Our results illustrate the progressive changes in the extracellular matrix features accompanying early ventricular remodelling in response to different degrees of pressure overload that may be involved in the development of cardiac electrical instability. We also demonstrate for the first time a linear correlation between an increase in ,-skeletal actin expression and the degree of compensated cardiac hypertrophy, possibly acting as an early compensatory mechanism to maintain normal mechanical performance. [source] Rethinking Law and Violence: The Domestic Violence (Prevention) Bill in India, 2002GENDER & HISTORY, Issue 3 2004Rajeswari Sunder Rajan This essay focuses on the controversy generated by recent proposed legislation on domestic violence in India. An alternative draft bill on domestic violence prepared by the feminist legal NGO, the Lawyers' Collective, and supported by women's groups nationally, includes a demand that victims of domestic violence (usually wives) be permitted by law to continue to occupy the domestic home, a demand that the Government bill has refused to include. This demand is theoretically informed by a politics of space. Bodies and space are linked, to the extent that each is an abstraction without the concept of the other to ground it. The feminist legal proposal challenges property-as-absolute-(male) ownership by conceptualising the household as, instead, shared domestic space. The proposal does not dissimulate common sense , it is conscious of being radical, in part at least because it demystifies the ,domestic' as an ideological construct and offers it instead realistically and minimally as simply an alternative to destitution. The recognition that there are no support structures for dependant women outside the family (such as, for example, state-sponsored welfare institutions), so that destitution can be both sudden and real for women of any class and circumstances, has led to the conceptualisation of a law that formulates a right to shared space as one that makes no claim to shared ownership , while at the same time questioning the other's absolute property right. Despite the limited nature of the claim it makes, this proposal has been viewed as threatening by Indian law-makers. [source] Asylum and the Expansion of Deportation in the United Kingdom1GOVERNMENT AND OPPOSITION, Issue 2 2008Matthew J. Gibney Deportation has traditionally been seen as a secondary instrument of migration control, one used by liberal democratic states relatively infrequently and with some trepidation. This secondary status has been assured by the fact that deportation is both a complicated and a controversial power. It is complicated because tracking individuals down and returning them home are time-consuming and resource-intense activities; it is controversial because deportation is a cruel power, one that sometimes seems incompatible with respect for human rights. In the light of these constraints, how can one explain the fact that since 2000 the United Kingdom has radically increased the number of failed asylum seekers deported from its territory? I argue in the article that this increase has been achieved through a conscious and careful process of policy innovation that has enabled state officials to engage in large-scale expulsions without directly violating liberal norms. [source] The Kingdom of Sicily and the Kingdom of England, 1066,1266HISTORY, Issue 292 2003G. A. Loud This article looks back from the political crisis in England in the 1250s to examine English and Anglo-Norman perceptions of southern Italy and Sicily, and contacts between the two regions, over the previous two centuries. Although some at least were conscious of a common Norman heritage, commentators from England knew relatively little of the southern kingdom; certainly less than the Norman chroniclers, Orderic Vitalis and Robert of Torigni, and even they were less well informed than has been suggested in the past. There was a period of increased diplomatic contact for a generation or so after 1160, in which the Becket dispute played a part, culminating in the visit of Richard I to Sicily during the Third Crusade although that episode did nothing to increase the warmth of Anglo-Sicilian relations. Thereafter there was relatively little contact for the next half-century, in spite of Frederick II's marriage to the sister of Henry III of England in 1235. Furthermore, Sicily was always perceived as an exotic and alien region indicating that the perceptions found in the 1250s had been anticipated at an earlier period. [source] Mapping the time course of nonconscious and conscious perception of fear: An integration of central and peripheral measuresHUMAN BRAIN MAPPING, Issue 2 2004Leanne M. Williams Abstract Neuroimaging studies using backward masking suggest that conscious and nonconscious responses to complex signals of fear (facial expressions) occur via parallel cortical and subcortical circuits. Little is known, however, about the temporal differentiation of these responses. Psychophysics procedures were first used to determine objective thresholds for both nonconscious detection (face vs. blank screen) and discrimination (fear vs. neutral face) in a backward masking paradigm. Event-related potentials (ERPs) were then recorded (n = 20) using these thresholds. Ten blocks of masked fear and neutral faces were presented under each threshold condition. Simultaneously recorded skin conductance responses (SCRs) provided an independent index of stimulus perception. It was found that Fear stimuli evoked faster SCR rise times than did neutral stimuli across all conditions, indicating that emotional content influenced responses, regardless of awareness. In the first 400 msec of processing, ERPs dissociated the time course of conscious (enhanced N4 component) from nonconscious (enhanced N2 component) perception of fear, relative to neutral. Nonconscious detection of fear also elicited relatively faster P1 responses within 100 msec post-stimulus. The N2 may provide a temporal correlate of the initial sensory processing of salient facial configurations, which is enhanced when top-down cortical feedback is precluded. By contrast, the N4 may index the conscious integration of emotion stimuli in working memory, subserved by greater cortical engagement. Hum. Brain Mapping 21:64,74, 2004. © 2003 Wiley-Liss, Inc. [source] Psychoanalytic perspectives on sport: a critical reviewINTERNATIONAL JOURNAL OF APPLIED PSYCHOANALYTIC STUDIES, Issue 4 2008Marcus Free Abstract Critically reviewing and comparing various psychoanalytic perspectives on conscious and unconscious motivations in sport, this paper contends that the appeal of sports participation may variously derive from its simultaneously involving the indulgence of pre-Oedipal and Oedipal symbolism within the outward maturity and disciplining frame of a post-Oedipal symbolic form. It considers differences between distinct psychoanalytic frames, favouring Kleinian and object relations above Lacanian approaches, based on their closer attention to the corporeality and sensuousness of sports participation and the conscious and unconscious fantasies embedded in it. Sport's sensuous corporeality, which enables its embodiment of pre-Oedipal fantasy as well as post-Oedipal submission to social reality, lies at the heart of its appeal. Copyright © 2008 John Wiley & Sons, Ltd. [source] The psychology and ideology of an islamic terrorist leader: Usama bin LadenINTERNATIONAL JOURNAL OF APPLIED PSYCHOANALYTIC STUDIES, Issue 2 2004Maria T. Miliora Abstract This essay presents what the author proposes are the motivational bases for Usama bin Laden's avowed "holy war" against the United States. Bin Laden's biography is presented against the backdrop of the recent political history of the Middle Eastern Islamic world including the emergence of radical Islam. In assessing bin Laden's personality from the data that are available, three features are prominent: archaic narcissistic states (expressed as conscious and unconscious fantasies), paranoia and a Manichean sense of reality. It is shown that his ideology derives from his personality and his perception of and reaction to political events involving the United States and nations in the Middle East. The findings suggest that bin Laden imagines that he is walking in the shoes of the prophet Muhammad as he engages in an apocalyptic war to restore Islam as a potent force in the world. Usama bin Laden is compared to Hitler as a charismatic, messianic leader. Copyright © 2004 Whurr Publishers Ltd. [source] An examination of the values that motivate socially conscious and frugal consumer behavioursINTERNATIONAL JOURNAL OF CONSUMER STUDIES, Issue 2 2009Miriam Pepper Abstract This article extends social psychological research on the motivations for sustainable consumption from the predominant domain of ecologically conscious consumer behaviour to socially conscious and frugal consumer behaviours. A UK-based survey study examines relationships between socially conscious and frugal consumer behaviours and Schwartz's value types, personal and socio-political materialism, and demographics among the general public. Socially conscious consumer behaviour, like its ecological counterpart, appears to be an expression of pro-social values. In contrast, frugal consumer behaviour relates primarily to low personal materialism and income constraints. As such, it does not yet represent a fully developed moral challenge to consumerism. [source] Understanding gay consumers' clothing involvement and fashion consciousnessINTERNATIONAL JOURNAL OF CONSUMER STUDIES, Issue 5 2007Ou Sha Abstract This study's primary objective was to provide a better understanding of gay consumers' clothing involvement and fashion consciousness. Personal in-depth interviews were conducted with 13 gay professionals in Canada. One hundred and forty-five usable survey questionnaires were also collected from gay consumers. The Fashion Involvement Index Scale (FII scale) was adapted for this study. Interview participants indicated that, in general, gay men tend to be more fashion conscious than heterosexual men. Survey results also indicated two dimensions, fashion interest and fashion awareness that were found to be stronger for this group of gay consumers than for heterosexual men. The FII value for the survey participants also resulted in a sum score mean value of 11.2, a medium level of fashion involvement that is a slightly higher level than has been found for heterosexual consumers. Interestingly, this study does not provide strong evidence of gay consumers' involvement in cutting-edge fashion trends. [source] Combating deceptive advertisements and labelling on food products , an exploratory study on the perceptions of teachersINTERNATIONAL JOURNAL OF CONSUMER STUDIES, Issue 3 2003Wai-ling Theresa Lai Yeung People are becoming more health conscious nowadays, but most of them are not able to adopt a lifestyle with adequate physical exercise and a healthier eating pattern. Many attempt to compensate by taking ,health foods'. Despite the recent economic recession, the functional food market expands rapidly in Asian countries. Recent statistics indicate a huge increase in weight loss and functional food product advertising expenditure in Hong Kong and other Asian countries. In a massive survey conducted by the Hong Kong Consumer Council, it was found that 85% of the medicines, health food and therapies sampled contain questionable claims and misleading messages (Consumer Council, 1999). In fact, young people do not understand much about modern food processing, in particular those present in low energy and functional foods, and they know very little about the modern food marketing strategies. The situation is detrimental to consumer welfare especially to the younger generation. This study attempts to reflect critically on the implications of these issues for the health and well-being of young people in Hong Kong. It explores directions for designing relevant and effective education programmes to empower young people in understanding food advertising strategies and making informed decisions on food choice. The paper will begin with a critical review on the current situation in Hong Kong. An interview survey on preservice and in-service teachers' perception towards misleading food advertising and labelling will then be reported. The situations at schools will be defined and problems faced by teachers in providing relevant consumer education programmes to students will be identified. Finally, the study will look to the future, with a view to developing students' critical skills in evaluating claims offered in food advertisements. [source] Geothermal-based hydrogen production using thermochemical and hybrid cycles: A review and analysisINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 9 2010M. Tolga Balta Abstract Geothermal-based hydrogen production, which basically uses geothermal energy for hydrogen production, appears to be an environmentally conscious and sustainable option for the countries with abundant geothermal energy resources. In this study, four potential methods are identified and proposed for geothermal-based hydrogen production, namely: (i) direct production of hydrogen from the geothermal steam, (ii) through conventional water electrolysis using the electricity generated through geothermal power plant, (iii) by using both geothermal heat and electricity for high temperature steam electrolysis and/or hybrid processes, and (iv) by using the heat available from geothermal resource in thermochemical processes. Nowadays, most researches are focused on high-temperature electrolysis and thermochemical processes. Here we essentially discuss some potential low-temperature thermochemical and hybrid cycles for geothermal-based hydrogen production, due to their wider practicality, and examine them as a sustainable option for hydrogen production using geothermal heat. We also assess their thermodynamic performance through energy and exergy efficiencies. The results show that these cycles have good potential and attractive overall system efficiencies over 50% based on a complete reaction approach. The copper-chlorine cycle is identified as a highly promising cycle for geothermal-hydrogen production. Copyright © 2009 John Wiley & Sons, Ltd. [source] | ||||||||||||||||||||||||||||||||||||||||||||||||||||