Home About us Contact
|
Home About us Contact | ||
|
|
||
Conduit
Kinds of Conduit Terms modified by Conduit Selected AbstractsENDOTHELIAL FUNCTION OF CONDUIT AND RESISTANCE ARTERIES IN NEPHROTIC RANGE PROTEINURIANEPHROLOGY, Issue 3 2000G. Dogra OBJECTIVE: To test the hypothesis that endothelial dysfunction occurs in nephrotic range proteinuria primarily as a consequence of dyslipidaemia. METHODS: Brachial artery and forearm microcirculatory endothelial function was compared among patients with nephrotic range proteinuria (NRP, n = 14 ), primary hyperlipidaemia (HL, n = 15) and normal controls (NC, n = 16). Endothelial function was studied by measuring post-ischaemic flow-mediated dilatation (FMD) of the brachial artery using high resolution ultrasonography. Endothelium-independent, glyceryl trinitrate (GTN) mediated brachial artery vasodilatation was also measured. Basal and post-ischaemic blood flow of the forearm microcirculation was measured using venous-occlusion strain gauge plethysmography. RESULTS: Serum creatinine was similar among groups. The proteinuric group had a mean albumin of 27.6g/L(1.8) and 24-hour urinary protein excretion of 6.3g(1.3). Plasma lipids and lipoproteins were not statistically different between the NRP and HL groups. Brachial artery FMD was significantly lower in the NRP and HL groups compared with the controls (NRP 4.7%(1.3)*, HL 4.9%(0.7)* and NC 8.3%(0.6), *p = 0.012 vs. NC); GTN mediated dilatation and basal and post-ischaemic forearm blood flow were not statistically different among the three groups. CONCLUSION: Patients with nephrotic range proteinuria have endothelial dysfunction of conduit arteries in the peripheral circulation, similar to that observed in patients with primary hyperlipidaemia. This suggests dyslipoproteinaemia is the principal cause of endothelial dysfunction of conduit arteries in nephrotic range proteinuria. Confirmation of this should be sought with an intervention trial of lipid-regulating therapy. [source] Stent Dilatation of a Right Ventricle to Pulmonary Artery Conduit in a Postoperative Patient with Hypoplastic Left Heart SyndromeCONGENITAL HEART DISEASE, Issue 2 2008Rowan Walsh MD ABSTRACT A 10-day-old child with hypoplastic left heart syndrome (HLHS) underwent first-stage palliation for HLHS, Norwood procedure with a Sano modification, i.e., placement of a right ventricular to pulmonary artery (RV-PA) conduit. The patient developed progressively worsening systemic oxygen desaturation in the immediate postoperative period. Stenosis of the proximal RV-PA conduit was diagnosed by echocardiography. In the catheterization laboratory stent placement in the conduit was performed. This resulted in increased systemic oxygen saturation. The patient was eventually discharged from the hospital with adequate oxygen saturations. [source] Negative Pressure Wound Therapy Used to Heal Complex Urinary Fistula Wounds Following Renal Transplantation into an Ileal ConduitAMERICAN JOURNAL OF TRANSPLANTATION, Issue 10 2010Sarah Heap Transplantation into an ileal conduit is an established option for patients with end-stage renal failure and a nonfunctioning urinary tract. Urinary fistulae are more common following these complex transplants. Urinary fistula in this scenario can cause substantial morbidity and even result in graft loss. The management options depend on the viability of the transplant ureter, the level of local sepsis and the overall condition of the patient. Urinary diversion with a nephrostomy and ureteric stents has been described in aiding the healing of urinary leaks in renal transplants into a functioning urinary tract. We describe the successful use of negative wound pressure therapy to eradicate the local sepsis and help the healing of a recurrent urinary fistula following kidney transplantation into an ileal conduit. To our knowledge these are the first such cases reported in the literature. [source] Simultaneous Pancreas-Kidney Transplantation Utilizing a Common Arterial Conduit: Early Experience and Potential ApplicationsAMERICAN JOURNAL OF TRANSPLANTATION, Issue 11 2003Paul L. Tso Simultaneous pancreas-kidney transplantation has gained acceptance as a therapeutic modality for patients with end-stage renal disease secondary to diabetes mellitus. In some instances, performing the procedure as conventionally described with renal revascularization from the left iliac vessels and pancreatic arterial inflow from the right iliac vessels may be difficult or undesirable. We describe our experience with an alternate operative technique utilizing a single arterial conduit to vascularize both organs. We believe that this technique may be of use in certain patients undergoing simultaneous pancreas-kidney transplantation. [source] Early and Midterm Results of an Alternative Procedure to Homografts in Primary Repair of Truncus Arteriosus CommunisCONGENITAL HEART DISEASE, Issue 3 2010Pedro Curi-Curi MD ABSTRACT Background., Repair of truncus arteriosus communis (TAC) in the neonatal and early infant period has become a standard practice. We report our experience on primary repair of TAC with a bovine pericardial-valved woven Dacron conduit as an alternative procedure to homografts, with a focus on early and midterm results. Methods., From January 2001 to December 2007, 15 patients with mean age 1.5 years (range 3 months to 8 years), underwent primary repair of simple TAC. Cases with cardiogenic shock, complex-associated cardiac lesions, or adverse anatomy of the truncal valve were excluded. The Collett and Edwards anatomical type classification of TAC was as follows: type I, 13 (87%); and type II, 2 (13%). Right ventricular outflow tract was reconstructed in all the cases with a bovine pericardial-valved woven Dacron conduit. Results., Overall mortality was 6.6% (1 death due to severe pulmonary hypertension). At a mean follow-up of 31 months (range 6,51), there were no deaths (5-year actuarial survival 93.4%). Out of the 14 midterm survivors, three developed stenosis of the pericardial-valved woven Dacron conduit, but only one underwent interventional procedure including percutaneous balloon dilation with stenting for associated left pulmonary artery hypoplasia. The rate of patients with no surgical or percutaneous reinterventions performed because of obstruction of the right ventricular outflow tract reconstruction in the midterm (5 years) was 86%. Conclusions., Truncus arteriosus communis repair with a bovine pericardial-valved woven Dacron conduit can be performed with a very low perioperative mortality and satisfactory midterm morbidity, favorably compared with that reported for the use of homografts. Interventional cardiac catheterization may delay the time of reoperation for inevitable conduit replacement due to stenosis. [source] Stent Dilatation of a Right Ventricle to Pulmonary Artery Conduit in a Postoperative Patient with Hypoplastic Left Heart SyndromeCONGENITAL HEART DISEASE, Issue 2 2008Rowan Walsh MD ABSTRACT A 10-day-old child with hypoplastic left heart syndrome (HLHS) underwent first-stage palliation for HLHS, Norwood procedure with a Sano modification, i.e., placement of a right ventricular to pulmonary artery (RV-PA) conduit. The patient developed progressively worsening systemic oxygen desaturation in the immediate postoperative period. Stenosis of the proximal RV-PA conduit was diagnosed by echocardiography. In the catheterization laboratory stent placement in the conduit was performed. This resulted in increased systemic oxygen saturation. The patient was eventually discharged from the hospital with adequate oxygen saturations. [source] Schooling the Possible SelfCURRICULUM INQUIRY, Issue 4 2004CYNTHIA MCCALLISTER ABSTRACT From a social perspective, one's identity is entirely the product of interaction with others. As children participate in the vast range of social situations, they collect impressions of themselves that coalesce to form a sense of who they are, as well as a narrative framework that helps explain the world and their place within it. These insights create a dynamic identity that is stimulated by one's sense of potential and possibility. The social perspective provides a way to understand how school situations offer the substance from which children develop a sense of self. Literacy is a particularly powerful conduit for the development of self. An understanding of language and literacy, and how these processes are taken up by the child as means to shape his or her social connections and, by extension, his or her social reality, demands an understanding of self and how it evolves through interaction in a range of contexts. The purpose of this article is to describe how "self" plays out through literacy situations at home and school. Borrowing from social and cultural descriptions of the development of self, this article illustrates how these situations provide contexts for the expression and development of self, and offers implications for curriculum and classroom practice. [source] Channel head location and characteristics using digital elevation modelsEARTH SURFACE PROCESSES AND LANDFORMS, Issue 7 2006G. R. Hancock Abstract The drainage network is the conduit through which much surface water and sediment are routed within a catchment. In a catchment, the position of where hillslopes begin and channels end has long been considered the position of transition between diffusive processes upslope and the more incisive fluvial processes downslope. Consequently, understanding channel head location is an important issue in understanding catchment hydrology and geomorphology. This study examines channel head position and characteristics in a catchment in Arnhem Land, Northern Territory, Australia. In this study the position of channel heads was mapped within the catchment and plotted on a reliable digital elevation model of the catchment. It was found that the majority of channel heads have relatively small source areas and that graphical catchment descriptors, such as the area,slope relationship and cumulative area distribution, can provide reliable measures of the field position of the heads of first-order streams and the transition from hillslope to channel. The area,slope relationship and cumulative area distribution are also shown to be good tools for determining digital elevation model grid size which can capture hillslope detail and the transition from hillslope to channel. Copyright © 2005 John Wiley & Sons, Ltd. [source] Automated Volumetric Flow Quantification Using Angle-Corrected Color Doppler ImageECHOCARDIOGRAPHY, Issue 5 2004Beomjin Kim Ph.D. We have developed a fully automated method for measuring volumetric blood flow with angle-corrected blood velocity from a color Doppler image. By computing the blood flow vector through a conduit, the angle of incidence between the direction of ultrasound beam and the direction of blood flow can be measured to correct the underestimated blood velocity. This correction immediately contributes to the improvement of measurement accuracy. The developed method also enhances the conduit identification procedure that is one of the most important factors affecting the accuracy of volumetric measurement. To evaluate the validity of the developed algorithm, experimental studies had been applied to 21 healthy subjects and 10 patients. Volumetric flows were measured from a color Doppler image of the left ventricular outflow track, which were compared with blood volumes that were measured by traditional pulsed-wave (PW)-Doppler technique. The mean stroke volume difference between two methods was ,0.45 ± 11.7 (mean ± SD). The proposed algorithm is a viable method for determining blood flow volume in an automated fashion. (ECHOCARDIOGRAPHY, Volume 21, July 2004) [source] Commentary on Larney (2010): A call to action,opioid substitution therapy as a conduit to routine care and primary prevention of HIV transmission among opioid-dependent prisonersADDICTION, Issue 2 2010SANDRA A. SPRINGER No abstract is available for this article. [source] The Phenomenology of Space in Writing OnlineEDUCATIONAL PHILOSOPHY AND THEORY, Issue 1 2009Max Van Manen Abstract In this paper we explore the phenomenon of writing online. We ask, ,Is writing by means of online technologies affected in a manner that differs significantly from the older technologies of pen on paper, typewriter, or even the word processor in an off-line environment?' In writing online, the author is engaged in a spatial complexity of physical, temporal, imaginal, and virtual experience: the writing space, the space of the text, cyber space, etc. At times, these may provide a conduit to a writerly understanding of human phenomena. We propose that an examination of the phenomenological features of online writing may contribute to a more pedagogically sensitive understanding of the experiences of online seminars, teaching and learning. [source] Enhanced survival of vascular smooth muscle cells accounts for heightened elastin deposition in arteries of neonatal spontaneously hypertensive ratsEXPERIMENTAL PHYSIOLOGY, Issue 4 2010Silvia M. Arribas Abnormal stiffening and narrowing of arteries are characteristic features of spontaneously hypertensive rats (SHR). In this strain, we have previously demonstrated an increased elastin content and abnormal organization of lamellae in conduit and resistance arteries from neonatal rats that preceded the impending inward remodelling, increased vascular stiffness and development of hypertension. The aim of this study was to assess the mechanism responsible for such excessive and aberrant elastin deposition in SHR vessels during perinatal development. We compared elastin, collagen and fibronectin production (inmunocytochemistry and quantitative assay of metabolically labelled insoluble elastin), DNA content as well as cell proliferation (proliferative cellular nuclear antigen, bromodeoxyuridine incorporation) and death rates (propidium iodide exclusion test, terminal transferase nick and labeling (TUNEL) assay) in cultures of vascular smooth muscle cells (VSMC) derived from neonatal SHR and Wistar,Kyoto (WKY) control rats. Cultures of VSMC derived from neonatal SHR exhibited hypertrophy, produced more elastin, collagen and fibronectin and contained more DNA than equally plated WKY counterparts. Further analysis revealed that the higher net DNA content in SHR-derived cultures was due to increased diploidy, but not to a heightened cell multiplication. The SHR-derived VSMC also exhibited lower rates of cell death and apoptosis, which were associated with increased levels of the anti-apoptotic protein, survivin. We therefore conclude that the peculiar heightened survival of matrix-producing VSMC in neonatal SHR is responsible for accumulation of hard-wearing elastin and other extracellular matrix elements in the growing arteries, thereby contributing to the subsequent development of systemic hypertension. [source] Upwelling plumes, superswells and true polar wanderGEOPHYSICAL JOURNAL INTERNATIONAL, Issue 3 2004Marianne Greff-Lefftz SUMMARY The geological evolution of the rotational axis of the Earth is most likely controlled by internal mass redistribution within the mantle. Palaeomagnetic observations suggest that it is episodic in nature, with periods of quasi-standstill alternating with periods of faster wander. Here, we investigate two models for the influence of mantle plumes that vary at different spatial wavelengths on the time variations of the rotational axis (true polar wander; TPW). In the first model, we represent an upwelling plume as a sphere whose radius varies as a function of the flux of material in the conduit and that traverses the mantle at the Stokes velocity. Such a plume produces very little wander of the rotational axis. We then study the effects of two superswells that mimic the ones observed with seismic tomography and conclude that a doming regime within the mantle involves significant polar wander. Some of the features of this TPW that are directly linked to the periodicity of doming are reminiscent of observed phases of slow and fast TPW, with similar peak velocities. [source] Retroviral labeling of Schwann cells: In vitro characterization and in vivo transplantation to improve peripheral nerve regenerationGLIA, Issue 1 2001Afshin Mosahebi Abstract Transplantation of Schwann cells (SCs) is a promising treatment modality to improve neuronal regeneration. Identification of the transplanted cells is an important step when studying the development of this method. Genetic labeling is the most stable and reliable method of cell identification, but it is still unclear whether it has deleterious effect on SC characteristics. Our aim was to achieve a stable population of SCs transduced with the lacZ gene at a high frequency using a retroviral vector in vitro, and to follow the labeled SC in vitro to assess their viability and phenotypic marker expression. Furthermore, we transplanted lacZ -labeled SCs in a conduit to repair peripheral nerve to investigate their effect on nerve regeneration in vivo. Rat and human SCs were cultured and transduced with an MFG lacZ nls marker gene, achieving a transduction rate of 80% and 70%, respectively. Rat SCs were kept in culture for 27 weeks and examined every 4 weeks for expression of lacZ, viability, and phenotypic marker expression of GFAP, p75, MHC I and II. Throughout this period, transduced rat SCs remained viable and continued to proliferate. The proportion of cells expressing lacZ dropped only by 10% and the expression of phenotypic markers remained stable. Transduced human SCs were followed up for 4 weeks in culture. They proliferated and continued to express the lacZ gene and phenotypic marker expression of GFAP and p75 was preserved. Primary culture of transduced rat SCs were transplanted, syngeneically, in a conduit to bridge a 10 mm gap in sciatic nerve and the grafts were examined after 3 weeks for the presence and participation of labeled SCs and for axonal regeneration distance. Transplanted transduced rat SCs were clearly identified, taking part in the regeneration process and enhancing the axonal regeneration rate by 100% (at the optimal concentration) compared to conduits without SCs. Thus, retroviral introduction of lacZ gene has no deleterious effect on SCs in vitro and these SCs take part and enhance nerve regeneration in vivo. GLIA 34:8,17, 2001. © 2001 Wiley-Liss, Inc. [source] Not seeing the ocean for the islands: the mediating influence of matrix-based processes on forest fragmentation effectsGLOBAL ECOLOGY, Issue 1 2006John A. Kupfer ABSTRACT The pervasive influence of island biogeography theory on forest fragmentation research has often led to a misleading conceptualization of landscapes as areas of forest/habitat and ,non-forest/non-habitat' and an overriding focus on processes within forest remnants at the expense of research in the human-modified matrix. The matrix, however, may be neither uniformly unsuitable as habitat nor serve as a fully,absorbing barrier to the dispersal of forest taxa. In this paper, we present a conceptual model that addresses how forest habitat loss and fragmentation affect biodiversity through reduction of the resource base, subdivision of populations, alterations of species interactions and disturbance regimes, modifications of microclimate and increases in the presence of invasive species and human pressures on remnants. While we acknowledge the importance of changes associated with the forest remnants themselves (e.g. decreased forest area and increased isolation of forest patches), we stress that the extent, intensity and permanence of alterations to the matrix will have an overriding influence on area and isolation effects and emphasize the potential roles of the matrix as not only a barrier but also as habitat, source and conduit. Our intention is to argue for shifting the examination of forest fragmentation effects away from a patch-based perspective focused on factors such as patch area and distance metrics to a landscape mosaic perspective that recognizes the importance of gradients in habitat conditions. [source] Application of Direct Push Methods to Investigate Uranium Distribution in an Alluvial AquiferGROUND WATER MONITORING & REMEDIATION, Issue 4 2009Wesley McCall The U.S. EPA 2000 Radionuclide Rule established a maximum contaminant level (MCL) for uranium of 30 µg/L. Many small community water supplies are struggling to comply with this new regulation. At one such community, direct push (DP) methods were applied to obtain hydraulic profiling tool (HPT) logs and install small diameter wells in a section of alluvial deposits located along the Platte River. This work was conducted to evaluate potential sources of elevated uranium in the Clarks, Nebraska drinking water supply. HPT logs were used to understand the hydrostratigraphy of a portion of the aquifer and guide placement of small diameter wells at selected depth intervals. Low-flow sampling of the wells provided water quality parameters and samples for analysis to study the distribution of uranium and variations in aquifer chemistry. Contrary to expectations, the aquifer chemistry revealed that uranium was being mobilized under anoxic and reducing conditions. Review of the test well and new public water supply well construction details revealed that filter packs extended significantly above the screened intervals of the wells. These filter packs were providing a conduit for the movement of groundwater with elevated concentrations of uranium into the supply wells and the community drinking water supply. The methods applied and lessons learned here may be useful for the assessment of unconsolidated aquifers for uranium, arsenic, and many other drinking water supply contaminants. [source] Authority, accountability and representation: the United Provinces police and the dilemmas of the colonial policeman in British India, 1902,39*HISTORICAL RESEARCH, Issue 192 2003David A. Campion This article examines police administration and the experience of colonial policing in the villages and towns of the United Provinces of Agra and Oudh, one of the largest and most important regions of British India in the early twentieth century. During this time it was the inefficiency and weakness of the British in their policing methods, rather than the brutally effective use of the Indian Police Service, that fuelled resentment among the population of colonial India and led to widespread discontent among European and Indian officers and constables. Yet throughout this period, the police remained the most important link between Europeans and Indians, and were a frequent conduit for social exchange as well as a point of bitter conflict. [source] Tumor metastasis and the lymphatic vasculatureINTERNATIONAL JOURNAL OF CANCER, Issue 12 2009Jonathan P. Sleeman Abstract Tumor-associated lymphatic vessels act as a conduit by which disseminating tumor cells access regional lymph nodes and form metastases there. Lymph node metastasis is of major prognostic significance for many types of cancer, although lymph node metastases are themselves rarely life-threatening. These observations focus our attention on understanding how tumor cells interact with the lymphatic vasculature, and why this interaction is so significant for prognosis. Tumors interact with the lymphatic vasculature in a number of ways, including vessel co-option, chemotactic migration and invasion into lymphatic vessels and induction of lymphangiogenesis. Tumor-induced lymphangiogenesis both locally and in regional lymph nodes has been correlatively and functionally associated with metastasis formation and poor prognosis. The investigation of the molecular regulation of lymphangiogenesis has identified ways of interfering with prolymphangiogenic signaling. Blockade of tumor-induced lymphangiogenesis in preclinical models inhibits metastasis formation in lymph nodes and often also in other organs, suggesting that blocking the lymphatic route of dissemination might suppress metastasis formation not only in lymph nodes but also in other organs. However, randomized clinical trials that have investigated the efficacy of therapeutic removal of lymph nodes have concluded that lymph node metastases act only as indicators that primary tumors have developed metastatic potential, and do not govern the further spread of metastatic cells. To reconcile these apparently paradoxical observations we suggest a model in which tumor-induced lymphangiogenesis and lymph node metastasis formation act as indicators that tumors are producing factors that can act systemically to promote metastasis formation in distant organs. © 2009 UICC [source] Robotic assisted radical cystectomy: short to medium-term oncologic and functional outcomesINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 11 2008P. Dasgupta Summary Purpose:, To report short- and medium-term oncological and functional outcomes of the first robotic-assisted laparoscopic radical cystectomy (RARC) series from the UK. Materials and methods:, Thirty patients underwent RARC between 2004 and 2007 at our unit. We report oncological and functional outcomes of this procedure in 20 patients (17 ileal conduit and three Studer Pouches), who have completed at least 6 months of follow up. Results:, There were 17 men and three women, median age 66 years (range 38,77 years). Median operating time was 330 min (range 295,510 min), and median blood loss 150 ml (range 100,1150 ml). There were two major complications (10%); a port site bleed and a rectal injury. The median follow up of this cohort is 23 months (range 7,44 months). One patient died of distant metastases at 8 months, and another developed a right ureteric tumour at 7 months. None of the patients had local pelvic or port site recurrence. The overall and disease-free survival are 95% and 90% respectively. Functional complications included a neovesico-urethral stricture at 3 months, a left upper ureteric stricture at 6 months and an incisional hernia at 12 months. Conclusion:, Robotic-assisted laparoscopic radical cystectomy is an emerging minimally invasive procedure which at short- to medium-term follow up, in our experience, is oncologically and functionally equivalent to open radical cystectomy. [source] Late malignant change in an ileal conduitINTERNATIONAL JOURNAL OF UROLOGY, Issue 1 2008Sally Wielding Abstract: Around 3000 bowel segment transpositions are performed in the UK each year and although malignancy is well-recognized following ureterosigmoidostomy, reports of similar changes in ileal conduits are sparse. We report a case of ileal adenocarcinoma in a 67-year-old lady some 49 years after ileal conduit, demonstrating previously unassociated histopathological features similar to those seen in collagenous colitis. [source] Hemiresective reconstruction of a redundant ileal conduit with severe bilateral ileal conduit-ureteral re,uxINTERNATIONAL JOURNAL OF UROLOGY, Issue 10 2005TETSUYA FUJIMURA Abstract A 58-year-old man was referred to our hospital with high fever and anuria. Since undergoing a total pelvic exenteration due to bladder-invasive sigmoid colon cancer, urinary tract infections had frequently occurred. We treated with the construction of a bilateral percutaneous nephrostomy (PCN), and chemotherapy. Although we replaced the PCN with a single J ureteral catheter after an improvement of infection, urinary infection recurred because of an obstruction of the catheter. Urological examinations showed that an ileal conduit-ureteral re,ux caused by kinking of the ileal loop was the reason why frequent pyelonephritis occurred. We decided to resect the proximal segment to improve conduit-ureteral re,ux for the resistant pyelonephritis. After the surgery, the excretory urogram showed improvement and the urinary retention at the ileal conduit disappeared. Three years after the operation, renal function has been stable without episodes of pyelonephritis. Here we report a case of open repair surgery of an ileal conduit in a patient with severe urinary infection. [source] Postoperative morbidity, functional results and quality of life of patients following orthotopic neobladder reconstructionINTERNATIONAL JOURNAL OF UROLOGY, Issue 3 2003Tatsuaki Yoneda Abstract Aim: To evaluate postoperative morbidity, functional results and health-related quality of life of patients with an orthotopic neobladder. Methods: A total of 37 patients with orthotopic neobladder (modified Studer method: 35 cases; Hautmann method: one case; sigmoid neobladder: one case) were included in the present study. Postoperative morbidity and neobladder function were analyzed. To determine quality of life, the Sickness Impact Profile questionnaire was used. The quality of life of patients who underwent orthotopic neobladder was compared with that of patients who underwent ileal conduit. Results: In 37 consecutive patients with neobladder reconstruction, early complications included 10 cases of pyelonephritis (27.0%) and one of stenosis of ureterointestinal anastomosis (2.7%). Two patients died of ARDS and sepsis following peritonitis and pneumonia in the perioperative period. Late complications included pyelonephritis in three patients (8.6%). In 32 cases, except for an early postoperative case and those that died, complete daytime and night-time continence was achieved in 31 patients (96.9%) and 16 patients (50.0%), respectively. Concerning health-related quality of life, the mean sum scores per category of the Sickness Impact Profile were calculated for 32 patients with orthotopic neobladder and 30 patients with ileal conduit. There were no significant differences in overall satisfaction, however, the scores for patients with orthotopic neobladder reconstruction were significantly higher than those for patients with ileal conduit in the three categories of emotions, feelings and sensation, social interaction and recreation. Conclusion: Orthotopic neobladder reconstruction exhibited good functional results with acceptable complications. Patients who underwent neobladder reconstruction were satisfied with their voiding. Assessment of quality of life using the Sickness Impact Profile questionnaire demonstrated that orthotopic neobladder improved their quality of life better than ileal conduit, especially with regard to mental, physical and social functioning in daily life. [source] Appendicovesicostomy for pubescent patients with neurogenic bladder using umbilicus as a stomal siteINTERNATIONAL JOURNAL OF UROLOGY, Issue 5 2002Akiko Uda Abstract We experienced two cases of neurogenic bladder in which clean intermittent catheterization (CIC) had been performed since early childhood. In both cases, CIC had not provided adequate voiding control and incontinence persisted. According to the Mitrofanoff Principle, we used the appendix as a catheterizable conduit, which was constructed to the umbilicus. [source] In situ hydraulic tests in the active fault survey tunnel, Kamioka Mine, excavated through the active Mozumi-Sukenobu Fault zone and their hydrogeological significanceISLAND ARC, Issue 4 2006Tsuyoshi Nohara Abstract The spatial hydrogeological and structural character of the active Mozumi-Sukenobu Fault (MSF) was investigated along a survey tunnel excavated through the MSF in the Kamioka Mine, central Japan. Major groundwater conduits on both sides of the MSF are recognized. One is considered to be a subvertical conduit between the tunnel and the surface, and the other is estimated to be a major reservoir of old meteoric water alongside the MSF. Our studies indicate that part of the MSF is a sub-vertical continuous barrier that obstructs younger meteoric water observed in the south-eastern part of the Active Fault Survey Tunnel (AFST) and water recharge to the rock mass intersected by the north-western part of the AFST. The MSF might be a continuous barrier resulting in the storage of a large quantity of older groundwater to the northwest. The observations and results of in situ hydraulic tests indicate that the major reservoir is not the fault breccia associated with the northeast,southwest trending faults of the MSF, but the zone in which blocks of fractured rocks occur beside high angle faults corresponding to X shears whose tectonic stress field coincides with the present regional stress field and antithetic Riedel shears of the MSF. The results from borehole investigations in the AFST indicate that secondary porosity is developed in the major reservoir due to the destruction of filling minerals and fracture development beside these shears. The increase in hydraulic conductivity is not directly related to increased density of fractures around the MSF. Development of secondary porosity could cause the increase in hydraulic conductivity around the MSF. Our results suggest that minor conduits of the fracture network are sporadically distributed in the sedimentary rocks around the MSF in the AFST. [source] Language Games and Natural ReactionsJOURNAL FOR THE THEORY OF SOCIAL BEHAVIOUR, Issue 1 2004David Rubinstein Ludwig Wittgenstein imagines a variety of eccentric social practices,like a tribe trained "to give no expression of feeling of any kind". But he also speaks of "the common behavior of mankind" that is rooted in "natural/primitive reactions". This emphasis on the uniformities of human behavior raises questions about the plausibility of some of his imagined language games. Indeed, it suggests the claim of evolutionary psychologists that there are biologically based human universals that shape social practices. But in contrast to E.O. Wilson's belief that "genes hold culture on a leash", Wittgenstein sees culture as a mediator,rather than a conduit,of "natural reactions". This suggests that social science can incorporate the claims of evolutionary psychology without scanting the centrality of culture in action and allows that nature can be overwhelmed by culture. [source] A composite poly-hydroxybutyrate,glial growth factor conduit for long nerve gap repairsJOURNAL OF ANATOMY, Issue 6 2003P.-N. Mohanna Abstract There is considerable evidence that peripheral nerves have the potential to regenerate in an appropriate microenvironment. We have developed a novel artificial nerve guide composed of poly 3-hydroxybutyrate (PHB) filled with glial growth factor (GGF) suspended in alginate hydrogel. Gaps of 2,4 cm in rabbit common peroneal nerve were bridged using a PHB conduit containing either GGF in alginate hydrogel (GGF) or alginate alone (Alginate), or with an empty PHB conduit (Empty). Tissues were harvested 21, 42 and 63 days post-operatively. Schwann cell and axonal regeneration were assessed using quantitative immunohistochemistry. At 21 days, addition of GGF increased significantly the distance of axonal and Schwann cells regeneration in comparison with that observed in Alginate and Empty conduits for both gap lengths. The axons bridged the 2-cm GGF conduits gap by 63 days, with a comparable rate of regeneration seen in 4-cm conduits. Schwann cells and axonal regeneration quantity was similar for both gap lengths in each group. However, at all time points the quantity of axonal and Schwann cells regeneration in GGF grafts was significantly greater than in both Alginate and Empty conduits, the latter showing better regeneration than Alginate conduits. The results indicate an inhibitory effect of alginate on regeneration, which is partially reversed by the addition of GGF to the conduits. In conclusion, GGF stimulates a progressive and sustainable regeneration increase in long nerve gap conduits. [source] The interrelated dynamics of unemployment and low-wage employmentJOURNAL OF APPLIED ECONOMETRICS, Issue 3 2007Mark B. Stewart This paper examines the extent of state dependence in unemployment and the role played in this by intervening low-wage employment. A range of dynamic random and fixed-effects estimators are compared. Low-wage employment is found to have almost as large an adverse effect as unemployment on future prospects and the difference in their effects is found to be insignificant. Evidence is presented that low-wage jobs act as the main conduit for repeat unemployment and considerably increases its probability. Obtaining a higher-wage job reduces the increased risk of repeat unemployment to insignificance. Copyright © 2007 John Wiley & Sons, Ltd. [source] Regeneration of canine peroneal nerve with the use of a polyglycolic acid,collagen tube filled with laminin-soaked collagen sponge: a comparative study of collagen sponge and collagen fibers as filling materials for nerve conduitsJOURNAL OF BIOMEDICAL MATERIALS RESEARCH, Issue 6 2001Toshinari Toba Abstract A novel artificial nerve conduit was developed and its efficiency was evaluated on the basis of promotion of peripheral nerve regeneration across an 80-mm gap in dogs. The nerve conduit was made of a polyglycolic acid,collagen tube filled with laminin-soaked collagen sponge. Conduits filled with either sponge- or fiber-form collagen were implanted into an 80-mm gap of the peroneal nerve (five dogs for each form). Twelve months postoperatively nerve regeneration was superior in the sponge group both morphometrically (percentage of neural tissue: fiber: 39.7 ± 5.2, sponge: 43.0 ± 4.5, n=3) and electrophysiologically (fiber: CMAP 1.06 ± 0.077, SEP 1.32 ± 0.127 sponge: CMAP 1.04 ± 0.106, SEP 1.24 ± 0.197, n=5), although these differences were not statistically significant. The observed regeneration was complementary to successful results reported previously in the same model, in which collagen fibers exclusively were used. The results indicate a possible superiority of collagen sponge over collagen fibers as filling materials. In addition, the mass-producibility, superior scaffolding potential, and capacity for gradual release of soluble factors of the sponge provide make it an attractive alternative to fine fibers, which are both technologically difficult and costly to produce. This newly developed nerve conduit has the potential to enhance peripheral nerve regeneration across longer gaps commonly encountered in clinical settings. © 2001 John Wiley & Sons, Inc. J Biomed Mater Res (Appl Biomater) 58: 622,630, 2001 [source] Transpulmonary Stenting of Both Pulmonary Arteries with a Surgical Access through Redo SternotomyJOURNAL OF CARDIAC SURGERY, Issue 4 2009Yacine Aggoun M.D. He developed 21 months later stenosis at the origin of both pulmonary arteries. The conventional interventional catheterization approaches were not available due to femoral vein thrombosis and severe transient complete atrioventricular block due to the manipulations to catheterize the left pulmonary artery. The stenoses were treated by implant of stents using a surgical access to the proximal portion of a Contegra valved conduit (Medtronic, Inc., Minneapolis, MN, USA) by sternotomy. [source] "Cracking and Paving": A Novel Technique to Deliver a Thoracic Endograft Despite Ilio-Femoral Occlusive DiseaseJOURNAL OF CARDIAC SURGERY, Issue 2 2009Jacques Kpodonu M.D. High-risk surgical patients with ilio-femoral occlusive disease may not be amenable to general anesthesia and the construction of a retroperitoneal conduit. Methods and Results: We report the use of a novel technique consisting of cracking and paving of the ilio-femoral vessels with balloon angioplasty, followed by deployment of an endoconduit to deliver an endoluminal graft under local sedation to treat a high-risk 80-year-old patient with a thoracic aneurysm. Conclusion: High-risk surgical patients with iliofemoral disease can undergo endoluminal graft therapy to threat thoracic aortic aneurysms. [source] | ||||||||||||||||||||||||||||||||||||||||||||||