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Complete Failure (complete + failure)
Selected AbstractsEarly Complete Failures of Fixed Implant-Supported Prostheses in the Edentulous Maxilla: A 3-Year Analysis of 17 Consecutive Cluster Failure PatientsCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 2 2006Odont Dr/PhD, Torsten Jemt DDS ABSTRACT Background, Clusters of implant failures in the edentulous maxilla seem to occur in some patients. To create groups for analysis with higher numbers of these patients implies large original groups for inclusion. Purpose, The aim of this study was to retrospectively describe and compare a group of "cluster failure patients" with randomly selected patients treated in the edentulous maxilla. Materials and Methods, From a group of 1,267 consecutively treated patients in one clinic, all patients presenting failing fixed implant-supported prostheses within the first 3 years of follow-up were included. All patients were treated with turned titanium implants using two-stage surgery. A control group of equal number of patients were created for comparison. Data on patients were retrospectively retrieved from their records, and compared. Results, Seventeen patients (1.3%) met the inclusion criteria in the entire group. The bone resorption index revealed less bone quantity in the study group (p < .05) during implant placement, but there was no difference regarding primary implant stability at first-stage surgery. The distribution of short and long implants showed relatively higher number of short implants in the study group (p < .05), and more patients had a presurgical discussion on the risk of implant failure prior to treatment in this group (p < .05). Only 5 out of 102 implants (4.9%) were lost before prosthesis placement as compared to 38 and 25 lost implants during the following two years in the study group. Smoking habits and signs of bone loss related to periodontitis in the lower dentition were more frequent in the study group, but did not reach a significant level (p > .05). Conclusion, The results indicate that bone quantity, reflected in fixture length, has a significant impact on increased implant failure risk. Other factors of interest as predictors for implant failures could be smoking habits and also possibly signs of periodontitis in the opposing dentition. [source] REVIEW ARTICLE: Immunology of Pre-EclampsiaAMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, Issue 6 2010Christopher W. G. Redman Citation Redman CWG, Sargent IL. Immunology of Pre-eclampsia. Am J Reprod Immunol 2010 Pre-eclampsia develops in stages, only the last being the clinical illness. This is generated by a non-specific, systemic (vascular), inflammatory response, secondary to placental oxidative stress and not by reactivity to fetal alloantigens. However, maternal adaptation to fetal (paternal alloantigens) is crucial in the earlier stages. A pre-conceptual phase involves maternal tolerization to paternal antigens by seminal plasma. After conception, regulatory T cells, interacting with indoleamine 2,3-dioxygenase, together with decidual NK cell recognition of fetal HLA-C on extravillous trophoblast may facilitate placental growth by immunoregulation. Complete failure of this mechanism would cause miscarriage, while partial failure would cause poor placentation and dysfunctional uteroplacental perfusion. The first pregnancy preponderance and partner specificity of pre-eclampsia can be explained by this model. For the first time, the pathogenesis of pre-eclampsia can be related to defined immune mechanisms that are appropriate to the fetomaternal frontier. Now, the challenge is to prove the detail. [source] Allelopathic Effects of Parthenium hysterophorus Extracts on Seed Germination and Seedling Growth of Eragrostis tefJOURNAL OF AGRONOMY AND CROP SCIENCE, Issue 5 2002T. Tefera The present study was conducted to investigate the allelopathic effects of Parthenium hysterophorus weed on seed germination and seedling growth of tef. Flower, stem, root and leaf aqueous extracts of Parthenium at 0, 1, 5, and 10 % concentrations were applied to determine their effect on tef seed germination and seedling growth under laboratory conditions. Increasing concentrations of aqueous extracts of Parthenium from leaf and flower inhibited seed germination and complete failure of seed germination was recorded when the extract concentration from the leaf part was 10 %. In contrast, aqueous extracts from stem and root had no effect on tef seed germination. Roots appeared more sensitive to allelopathic effect than shoots. Extracts from flower, root and stem had a stimulatory effect on shoot length at all concentration levels, as against an inhibitory effect of leaf extracts. Root extracts at low concentration (1 %) greatly promoted root length but aqueous extracts from leaf and flower inhibited root length. [source] Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their nichesJOURNAL OF ANATOMY, Issue 1 2008Vanja Pekovic Abstract Adult stem cells have been identified in most mammalian tissues of the adult body and are known to support the continuous repair and regeneration of tissues. A generalized decline in tissue regenerative responses associated with age is believed to result from a depletion and/or a loss of function of adult stem cells, which itself may be a driving cause of many age-related disease pathologies. Here we review the striking similarities between tissue phenotypes seen in many degenerative conditions associated with old age and those reported in age-related nuclear envelope disorders caused by mutations in the LMNA gene. The concept is beginning to emerge that nuclear filament proteins, A-type lamins, may act as signalling receptors in the nucleus required for receiving and/or transducing upstream cytosolic signals in a number of pathways central to adult stem cell maintenance as well as adaptive responses to stress. We propose that during ageing and in diseases caused by lamin A mutations, dysfunction of the A-type lamin stress-resistant signalling network in adult stem cells, their progenitors and/or stem cell niches leads to a loss of protection against growth-related stress. This in turn triggers an inappropriate activation or a complete failure of self-renewal pathways with the consequent initiation of stress-induced senescence. As such, A-type lamins should be regarded as intrinsic modulators of ageing within adult stem cells and their niches that are essential for survival to old age. [source] The hypoxic threshold for maximum cardiac performance in rainbow trout Oncorhynchus mykiss (Walbaum) during simulated exercise conditions at 18° CJOURNAL OF FISH BIOLOGY, Issue 3 2007L. M. Hanson Perfused rainbow trout Oncorhynchus mykiss hearts exposed to simulated exercise conditions (hypoxia, hyperkalemia and acidosis) at 18° C experienced complete failure of maximum cardiac performance at oxygen tensions <5·6 kPa and partial failure at <6·7 kPa. This hypoxic threshold, which occurred in the presence of maximal adrenergic stimulation (500 nM adrenaline), is unusually high compared with previous results at a colder acclimation temperature. Cardiac failure was primarily due to significant decreases (P < 0·05) in heart rate rather than cardiac stroke volume at all hypoxia levels tested. [source] Identification of patients best suited for combined liver,kidney transplantation: Part IILIVER TRANSPLANTATION, Issue 3 2002Connie L. Davis MD Associate Professor of Medicine Liver-kidney transplantation (LKT) should be reserved for those recipients with primary disease affecting both organs. However, increasing transplant list waiting times have increased the development and duration of acute renal failure before liver transplantation. Furthermore, the need for posttransplant calcineurin inhibitors can render healing from acute renal failure difficult. Because of the increasing requests for and controversy over the topic of a kidney with a liver transplant (OLT) when complete failure of the kidney is not known, the following article will review the impact of renal failure on liver transplant outcome, treatment of peri-OLT renal failure, rejection rates after LKT, survival after LKT, and information on renal histology and progression of disease into the beginnings of an algorithm for making a decision about combined LKT. [source] The evolution of arthropod limbsBIOLOGICAL REVIEWS, Issue 2 2004Geoff A. Boxshall ABSTRACT Limb morphology across the arthropods is reviewed using external morphological and internal anatomical data from both recent and fossil arthropods. Evolutionary trends in limb structure are identified primarily by reference to the more rigorous of the many existing phylogenetic schemes, but no major new phylogenetic inferences are presented. Tagmosis patterns are not considered, although the origins and patterns of heteronomy within the postantennulary limb series are analysed. The phenomenon of annulation is examined and two basic types of annuli are recognised: terminal and intercalary. The annulation of the apical segment of a limb results in the formation of terminal flagella, and is typical of primarily sensory appendages such as insect and malacostracan antennules and maxillary palps of some hexapods. Intercalary annulation, arising by subdivision of existing subterminal segments, is common, particularly in the tarsal region of arthropodan walking limbs. Differentiating between segments and annuli is discussed and is recognised as a limiting factor in the interpretation of fossils, which usually lack information on intrinsic musculature, and in the construction of groundplans. Rare examples of secondary segmentation, where the criteria for distinguishing between segments and annuli fail, are also highlighted. The basic crown-group arthropodan limb is identified as tripartite, comprising protopodite, telopodite and exopodite, and the basic segmentation patterns of each of these parts are hypothesised. Possible criteria are discussed that can be used for establishing the boundary between protopodite and telopodite in limbs that are uniramous through loss of the exopodite. The subdivision of the protopodite, which is typical of the postantennulary limbs of mandibulates, is examined. The difficulties resulting from the partial or complete failure of expression of articulations within the mandibulate protopodite and subsequent incorporation of partial proto-podal segments into the body wall, are also discussed. The development and homology between the various exites, including gills, on the postantennulary limbs of arthropods are considered in some detail, and the question of the possible homology between crustacean gills and insect wings is critically addressed. The hypothesis that there are only two basic limb types in arthropods, antennules and postantennulary limbs, is proposed and its apparent contradiction by the transformation of antennules into walking limbs by homeotic mutation is discussed with respect to the appropriate level of serial homology between these limbs. [source] | ||||||||||||||||