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Comprehensive Two-dimensional Gas Chromatography (comprehensive + two-dimensional_gas_chromatography)
Selected AbstractsComprehensive Two-Dimensional Gas Chromatography , GC×GCJOURNAL OF SEPARATION SCIENCE, JSS, Issue 5-6 2004Philip Marriott [source] Quantitation of suspected allergens in fragrances (Part I): evaluation of comprehensive two-dimensional gas chromatography for quality controlFLAVOUR AND FRAGRANCE JOURNAL, Issue 2 2004Robert Shellie Abstract An evaluation of comprehensive two-dimensional (2D) gas chromatography (GC×GC) was performed to assess its suitability for the analysis of volatile fragrance components, recognized by the European Commission's Scienti,c Committee on Cosmetics and other Non-food Products (SCCNFP) as possible skin sensitizers. The 24 volatile components listed by the SCCNFP were baseline-resolved or better within one 30 min analysis. High-quality calibration data for standard mixtures were obtained, with R2 > 0.998 over the concentration range 2,1000 mg/l. However, the analysis of small spiked amounts of target compounds in truly complex fragrances was problematic, due to uncertainty in component assignment. The bene,ts and limitations of GC×GC are reported, and a discussion of the proposed directions for the solution of this analysis is provided. Copyright © 2004 John Wiley & Sons, Ltd. [source] Opportunities for ultra-high resolution analysis of essential oils using comprehensive two-dimensional gas chromatography: a reviewFLAVOUR AND FRAGRANCE JOURNAL, Issue 3 2003Robert Shellie Abstract In comprehensive 2D gas chromatography, the entire sample is simultaneously subjected to analysis on two capillary columns. By using a suitable modulation interface between the primary and secondary columns, hundreds of fast, second-dimension chromatograms are produced. The data from these chromatograms are treated such that a 3D surface plot or a 2D contour plot of the components' individual retention times, on each column, as well as peak responses, are represented. In a properly tuned comprehensive 2D chromatogram, the individual sample components are spread throughout a 2D separation space, providing a signi,cant increase in the probability of resolving a greater number of sample components without increasing the analysis time. Comprehensive 2D,GC has proved useful for high-resolution conventional essential oil analysis as well as high-resolution enantioselective essential oil analysis. Combining comprehensive 2D,GC with either a quadrupole or time-of-,ight mass spectrometer gives a powerful 3D analysis technique, which is extremely effective for complex sample analysis. The present status and opportunities arising from these ultra-high resolution approaches are discussed herein. Copyright © 2003 John Wiley & Sons, Ltd. [source] Characterization of biodiesel and biodiesel blends using comprehensive two-dimensional gas chromatographyJOURNAL OF SEPARATION SCIENCE, JSS, Issue 14 2008Warawut Tiyapongpattana Abstract In this work the development of a comprehensive 2-D GC flame ionization detection (GC×GC FID) method for biodiesel fuels is reported. This method is used for the analysis of fatty acid methyl esters (FAMEs) in both biodiesel (B100) and biodiesel blend (B5) samples. The separation of FAME was based on component boiling point in the first dimension and polarity in the second dimension by using a BPX5/BP20 column set to provide a measure of ,orthogonality' in the 2-D space. Here the columns are coupled with a cryogenic modulator operating in a novel temperature programmed mode (TM) whereby the cryotrap is progressively incremented in temperature as the oven temperature is increased. The final method employs eight cryotrap temperature settings. The developed GC×GC method is able to successfully characterize and identify both B100 and B5 FAME components, which are produced from a variety of vegetable oils, animal fats and waste cooking oils, with high precision. The method is capable of analysing FAME with carbon numbers C4,C24, and is particularly suitable to characterize various types of biodiesel, making it possible to differentiate the origin and type of FAME used in the biodiesel samples. [source] The evolution of comprehensive two-dimensional gas chromatography (GC×GC)JOURNAL OF SEPARATION SCIENCE, JSS, Issue 5-6 2004Tadeusz Górecki Abstract For a technology little over a decade old, comprehensive two-dimensional gas chromatography (GC×GC) has quickly reached the status of one of the most powerful analytical tools for volatile organic compounds. At the heart of any GC×GC system is an interface, which physically connects the primary and the secondary columns and acts to preserve the separation obtained in the first dimension (first column) while allowing additional separation in the second dimension. The paper presents a review of the technology, including fundamental principles of the technique, data processing and interpretation and a timeline of inventive contributions to interface design. In addition, applications of the technique are presented, with a more detailed discussion of selected examples. [source] Comprehensive two-dimensional gas chromatography-mass spectrometry: A reviewMASS SPECTROMETRY REVIEWS, Issue 2 2008Luigi Mondello Abstract Although comprehensive two-dimensional gas chromatography (GC,×,GC) has been on the scene for more than 15 years, it is still generally considered a relatively novel technique and is yet far from being fully established. The revolutionary aspect of GC,×,GC, with respect to classical multidimensional chromatography, is that the entire sample is subjected to two distinct analytical separations. The resulting enhanced separating capacity makes this approach a prime choice when GC analysts are challenged with highly complex mixtures. The combination of a third mass spectrometric dimension to a GC,×,GC system generates the most powerful analytical tool today for volatile and semi-volatile analytes. The present review is focused on the rather brief, but not scant, history of comprehensive two-dimensional GC-MS: the first experiments were carried out at the end of the 1990s and, since then, the methodology has been increasingly studied and applied. Almost all GC,×,GC-MS applications have been carried out by using either a time-of-flight or quadrupole mass analyzer; significant experiments relative to a variety of research fields, as well as advantages and disadvantages of the MS systems employed, are discussed. The principles, practical and theoretical aspects, and the most significant developments of GC,×,GC are also described. © 2008 Wiley Periodicals, Inc., Mass Spec Rev 27:101,124, 2008 [source] | ||||||||||