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Cowden's Syndrome (cowden + syndrome)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

Insular Thyroid Carcinoma in a Patient with Cowden Syndrome

THE LARYNGOSCOPE, Issue S1 2009
Henry R. Diggelmann MD
No abstract is available for this article. [source]

Cancer-associated genodermatoses: a personal history

EXPERIMENTAL DERMATOLOGY, Issue 9 2006
Walter H. C. Burgdorf
Abstract:, Cancer-associated genodermatoses are a group of genetic disorders inherited in an autosomal-dominant fashion in which unique cutaneous findings are a reliable marker for the risk of developing internal malignancies. The historical, clinical and dermatopathological aspects of basal cell nevus syndrome, Muir,Torre syndrome, Cowden syndrome, Carney complex and Birt,Hogg,Dubé syndrome are reviewed in a personal and informal fashion. The latest advances in the molecular genetics of the disorders are also summarized. [source]

Mucocutaneous papillomatous papules in Cowden's syndrome

CLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 2 2008
F. R. Jornayvaz
Summary Cowden syndrome (CS; also known as multiple hamartoma syndrome) is a rare autosomal dominant disorder characterized by multiple hamartomas and a high risk of development of thyroid, breast, endometrial and other cancers. The cardinal features of the disease, which often lead to diagnosis, include mucocutaneous papillomatous papules and trichilemmomas. Most affected people develop these characteristic lesions by the age of 20 years. Once diagnosed, gene identification can be offered to family members of affected patients. We report a case of the disease and briefly review the current literature. [source]

Cowden's syndrome (multiple hamartoma and neoplasia syndrome): diagnostic dilemmas in three cases

ORAL DISEASES, Issue 4 2000
SI Chaudhry
Cowden's syndrome is a multisystem disease inherited as an autosomal dominant trait with incomplete penetrance and variable expression. The disease has typical oral manifestations which often precede more systemic involvement, and the dental professional is therefore well placed to institute a regime of regular checks to ensure early treatment of any neoplasms which may occur. However, since not all of the classical signs are present in all patients, diagnosis may be difficult. The case report of a patient with most of the features of Cowden's syndrome is presented and features compared with two other possible cases. [source]

Mucocutaneous papillomatous papules in Cowden's syndrome

CLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 2 2008
F. R. Jornayvaz
Summary Cowden syndrome (CS; also known as multiple hamartoma syndrome) is a rare autosomal dominant disorder characterized by multiple hamartomas and a high risk of development of thyroid, breast, endometrial and other cancers. The cardinal features of the disease, which often lead to diagnosis, include mucocutaneous papillomatous papules and trichilemmomas. Most affected people develop these characteristic lesions by the age of 20 years. Once diagnosed, gene identification can be offered to family members of affected patients. We report a case of the disease and briefly review the current literature. [source]