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Coupling Reaction (coupling + reaction)
Kinds of Coupling Reaction Selected AbstractsAlternative Coupling Reaction with Unactivated Furan DerivativesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 23 2009Marc-André Giroux Abstract Treatment of various dienimides in the presence of a Lewis acid and (trimethylsiloxy)furan leads to the corresponding aniline furan-2(5H)-ones. The same treatment with furan yields a triaryl product and, surprisingly, a byproduct with a pentacyclo[5.4.0.0.0.0]undecane main core. The formation of this birdcage system containing nine stereogenic centres was produced with complete diastereoselectivity.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source] Suzuki,Miyaura Coupling Reaction of Boronic Acids and Ethyl Glyoxylate: Synthetic Access to Mandelate DerivativesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 34 2008Irene Notar Francesco Abstract The palladium-catalyzed coupling reaction of arylboronicacids with ethyl glyoxylate provides a straightforward method for the synthesis of mandelic esters. Pd2(dba)3·CHCl3 in combination with 2-di- tert -butylphosphanylbiphenyl as the catalytic system and Cs2CO3 as the base were used. The reaction tolerates a wide range of functionalized boronicacids. Mandelic esters were isolated in good-to-excellent yields with a variety of neutral, slightly electron-rich, and slightly electron-poor substituents.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] Monodisperse Nanoparticles of Ni and NiO: Synthesis, Characterization, Self-Assembled Superlattices, and Catalytic Applications in the Suzuki Coupling Reaction,ADVANCED MATERIALS, Issue 4 2005J. Park Monodisperse spherical Ni nanoparticles with diameters of 2 nm, 5 nm, and 7 nm were synthesized from the thermal decomposition of a Ni,oleylamine complex. Ni nanocrystal superlattices were generated via the controlled evaporation of solvent (see Figure). The nanoparticles were successfully used as catalysts for the Suzuki coupling reaction, and were readily oxidized to produce NiO nanoparticles. [source] Efficient and General Synthesis of 3-Aminoindolines and 3-Aminoindoles via Copper-Catalyzed Three-Component Coupling ReactionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 6 2010Dmitri Chernyak Abstract An efficient three-component coupling (TCC) reaction toward a variety of 3-aminoindoline and 3-aminoindole derivatives has been developed. This cascade transformation proceeds via the copper-catalyzed coupling reaction between 2-aminobenzaldehyde, a secondary amine, and an alkyne leading to a propargylamine intermediate which, under the reaction conditions, undergoes cyclization into the indoline core. The latter, upon treatment with a base, smoothly isomerizes into the indole. Alternatively, the indole can directly be synthesized in a one-pot sequential reaction. [source] Pyrazole Synthesis Using a Titanium-Catalyzed Multicomponent Coupling Reaction and Synthesis of WithasomnineADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Supriyo Majumder Abstract The titanium-catalyzed 3-component coupling of an alkyne, isonitrile, and amine can be used to generate tautomers of 1,3-diimines. These diimines produced in situ undergo cyclization with hydrazine and hydrazine derivatives in a one-pot procedure to provide pyrazoles. Seventeen examples of pyrazoles are provided using this one-pot, 4-component procedure from simple starting materials. The regioselectivity of the alkyne addition can be controlled in some cases with catalyst architecture, and regioselectivity of monosubsituted hydrazines to unsymmetrical 1,3-diimines is discussed. This multicomponent coupling strategy was applied to the synthesis of withasomnine in an efficient procedure, which gave the natural product in 24% overall yield from 4-pentyn-1-ol. [source] Stereoselective Synthesis of Multifunctionalized 1,2,4-Triazolidines by a Ruthenium Porphyrin-Catalyzed Three-Component Coupling ReactionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16-17 2006Ming-Zhong Wang Abstract Multifunctionalized 1,2,4-triazolidines have been synthesized by a ruthenium porphyrin-catalyzed three-component coupling reaction. In a one-pot reaction, ruthenium porphyrins catalyzed the in situ generation of azomethine ylides from ,-diazo esters and imines. Stereoselective 1,3-dipolar cycloaddition reactions of the azomethine ylides with dialkyl azodicarboxylates gave the corresponding 1,2,4-triazolidines in good yields (up to 85,%). Using chiral 8-phenylmenthanol ,-diazo ester as the carbenoid source, chiral 1,2,4-triazolidines have been obtained with good diastereoselectivity (up to 84,% de). Some of the 1,2,4-triazolidines exhibited good cytotoxicity against human nasopharyngeal carcinoma (SUNE1) (IC50=10.4,,M) and human cervical carcinoma (Hela) (IC50=10.7,,M) cell lines. [source] New Second-Order Nonlinear Optical Polymers Derived from AB2 and AB Monomers via Sonogashira Coupling ReactionMACROMOLECULAR CHEMISTRY AND PHYSICS, Issue 8 2010Zhong'an Li Abstract In this paper, a facile route was designed to prepare a new AB2 -type polymer P1 via simple Sonogashira coupling reaction, also its corresponding linear analog (P2) was obtained from AB monomer for comparison. Despite the relatively lower loading density of the effective chromophore moieties, P1 demonstrated higher second-harmonic coefficient (153.9,pm,·,V,1) than that of P2 (98.2,pm,·,V,1), due to the three-dimensional spatial isolation effect of the hyperbranched structure. The good results of P2 also indicated that the ladder shape may help to solve the problem existing in main-chain polymers, the low poling efficiency. [source] Gold Nanoparticles Embedded in a Mesoporous Carbon Nitride Stabilizer for Highly Efficient Three-Component Coupling Reaction,ANGEWANDTE CHEMIE, Issue 34 2010Träger mit Dreifachfunktion: Au-Nanopartikel mit Größen unter 7,nm wurden in den Kanälen eines mesoporösen Kohlenstoffnitrid(MCN)-Trägers hergestellt, der als Stabilisator, zur Größenkontrolle und als Reduktionsmittel fungiert (siehe Bild; Au-NPs grün). Die eingebetteten, gut dispergierten Au-Nanopartikel sind hoch aktive, selektive und wiederverwendbare Katalysatoren in der Dreikomponentenkupplung von Benzaldehyd, Piperidin und Phenylacetylen zur Synthese von Propargylamin. [source] General and Efficient Copper-Catalyzed Three-Component Coupling Reaction towards Imidazoheterocycles: One-Pot Synthesis of Alpidem and Zolpidem,ANGEWANDTE CHEMIE, Issue 15 2010Natalia Chernyak Aus drei mach eins: Ein Verfahren, um Imidazopyridin-, Imidazochinolin- und Imidazoisochinolin-Gerüste herzustellen, wurde entwickelt, und sein präparativer Nutzen wurde mit einer hoch effizienten Eintopfsynthese der Wirkstoffe Alpidem und Zolpidem gezeigt (siehe Schema). [source] Zirconium- and Silicon-Containing Intermediates with Three Fused Rings in a Zirconocene-Mediated Intermolecular Coupling Reaction,ANGEWANDTE CHEMIE, Issue 39 2009Wen-Xiong Zhang Prof. Die Zr/Si-haltigen Schlüsselintermediate einer Zirconocen-vermittelten intermolekularen Kupplung wurden isoliert und charakterisiert (siehe Schema). Der weitere Verbleib der funktionellen Gruppen und das Reaktionsverhalten der Zwischenstufe 1 mit etlichen ungesättigten Substraten wurden ermittelt. [source] ChemInform Abstract: 2-Pyridyl and 3-Pyridylzinc Bromides: Direct Preparation and Coupling Reaction.CHEMINFORM, Issue 41 2010Seung-Hoi Kim Abstract 2-Pyridyl and 3-pyridylzinc bromides are readily prepared from the corresponding pyridylbromides and Rieke zinc. [source] ChemInform Abstract: Synthesis of Unexpected Pyrrolo[2,3-b]quinoxaline-2-carbaldehydes via Sonogashira Coupling Reaction.CHEMINFORM, Issue 37 2010Ali Keivanloo Abstract Pd-catalyzed reaction of 3-chloroquinoxalin-2-amines with propargyl bromide proceeds in the presence of wet morpholine to give the title compounds (III) unexpectedly. [source] ChemInform Abstract: Synthesis of Some New Biheterocycles by a One-Pot Suzuki,Miyaura Coupling ReactionCHEMINFORM, Issue 33 2010Mandar Deodhar Abstract involving in situ conversion of an aryl halide into a boronate ester intermediate followed by addition of a second equivalent of aryl halide together with an appropiate Pd-catalyst; (11 examples) [source] ChemInform Abstract: Application of a Readily Available and Air-Stable Monophosphine HBF4 Salt for the Suzuki Coupling Reaction of Aryl or 1-Alkenyl Chlorides.CHEMINFORM, Issue 25 2010Bo Lue Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Catalytic Performance of a Phosphapalladacycle Bearing a Biphenyl Moiety, Possessing an sp3 C,Pd Bond, Toward the Heck Coupling Reaction.CHEMINFORM, Issue 11 2010Shirin Nadri Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of N-Substituted Benzo[c][1,7]- and Benzo[c][1,8]phenanthrolin-(5H)-6-ones Through a Pd-Mediated Suzuki,Miyaura Heteroaryl-Aryl Coupling Reaction.CHEMINFORM, Issue 11 2010Constance Genes Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Iridium-Catalyzed Coupling Reaction of Primary Alcohols with 1-Aryl-1-propynes Leading to Secondary Homoallylic Alcohols.CHEMINFORM, Issue 49 2009Yasushi Obora Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Mild Copper-Mediated Glaser-Type Coupling Reaction under the Novel CuI/NBS/DIPEA Promoting System.CHEMINFORM, Issue 42 2009Lingjun Li Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Cyclic ,-Acylvinyl Anionic Synthons: A Novel Synthesis of 2-Trimethylsilyl-3-methyl-cyclohexenone by the Wurtz,Fittig Coupling Reaction.CHEMINFORM, Issue 33 2009Divya Jyothi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Gold(III) (C,N) Complex-Catalyzed Synthesis of Propargylamines via a Three-Component Coupling Reaction of Aldehydes, Amines and Alkynes.CHEMINFORM, Issue 27 2009Vanessa Kar-Yan Lo Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Facile Approach to Natural or Non-Natural Amino Acid Derivatives: Me3SiCl-Promoted Coupling Reaction of Organozinc Compounds with N,O-Acetals.CHEMINFORM, Issue 25 2009Norio Sakai Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: CuI/PPh3 -Catalyzed Sonogashira Coupling Reaction of Aryl Iodides with Terminal Alkynes in Water in the Absence of Palladium.CHEMINFORM, Issue 21 2009Jin Tao Guan Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Propylene Oxide Assisted Sonogashira Coupling Reaction.CHEMINFORM, Issue 16 2009Zhaolong Tong Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Suzuki,Miyaura Coupling Reaction of Boronic Acids and Ethyl Glyoxylate: Synthetic Access to Mandelate Derivatives.CHEMINFORM, Issue 11 2009Irene Notar Francesco Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of Highly Oxygenated Biphenyl Derivative (VI) in an Optically Active Form Through Palladium-Mediated Intramolecular Biaryl Coupling Reaction.CHEMINFORM, Issue 9 2009Hitoshi Abe Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient One-Pot Approach to Phenanthrene Derivatives Using a Catalyzed Tandem Ullmann-Pinacol Coupling Reaction.CHEMINFORM, Issue 7 2009Shuan-zheng Lin Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Novel Pd/Ag-Catalyzed Sonogashira Coupling Reaction of Terminal Alkynes with Hypervalent Iodonium Salts.CHEMINFORM, Issue 3 2009Min Zhu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Formation of Bicyclic Pyrroles from the Catalytic Coupling Reaction of 2,5-Disubstituted Pyrroles with Terminal Alkynes, Involving the Activation of Multiple C,H Bonds.CHEMINFORM, Issue 38 2008Chae S. Yi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Regioselective Synthesis of Trisubstituted Allenes (III) and (VI) via Lithiation of 1-Aryl-3-alkylpropadiene, Subsequent Transmetalation, and Pd-Catalyzed Negishi Coupling Reaction.CHEMINFORM, Issue 34 2008Jinbo Zhao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Substituent Effects in the Preparation of Naphthacenes by the Coupling Reaction of Diyne-Derived Zirconacyclopentadienes with Tetraiodobenzene.CHEMINFORM, Issue 27 2008Tomomi Seri Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] | |||||||||||||||||||||||||||||||