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Class II Furcation Defects (class + ii_furcation_defect)
Selected AbstractsAn evaluation of bovine derived xenograft with and without a bioabsorbable collagen membrane in the treatment of mandibular Class II furcation defectsAUSTRALIAN DENTAL JOURNAL, Issue 3 2009M Taheri Abstract Background:, The aim of this study was to compare the clinical outcomes of applying Bio-Oss®, an anorganic bovine bone xenograft (control group) to the combined use of Bio-Oss® and Bio-Gide® (a bioabsorbable collagen membrane) (test group) in human mandibular Class II furcation defects. Methods:, A total of 18 furcations (8 tests and 10 controls) in 14 patients suffering from chronic periodontitis were treated in this randomized clinical trial. Open vertical and horizontal furcation depths (OVFD and OHFD), vertical and horizontal clinical attachment levels (VCAL, HCAL), probing depth (PD) and free gingival marginal level (GML) were among the clinical parameters measured prior and six months after treatment, at re-entry surgery. The data were analysed by statistical tests while a p value less than 0.05 was considered significant. Results:, At the surgical re-entry, the mean reduction for OVFD of the control and test groups was 1.9 ± 1.3 and 2.1 ± 1.0, and for OHFD 2.1 ± 0.7 and 2.4 ± 1.3, respectively. The control and test treatments resulted in significant reductions in PD, VCAL and HCAL measurements at re-entry but there was no statistically significant difference between the two treatments in all soft and hard tissues measurements. Conclusions:, This clinical trial failed to demonstrate the superiority of the combined use of Bio-Gide® and Bio-Oss® to the use of Bio-Oss® alone, although both therapies resulted in significant gains in attachment level and bone fill. [source] A clinical study evaluating the treatment of supra-alveolar-type defects with access flap surgery with and without an enamel matrix protein derivative: a pilot studyJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 8 2008Holger Jentsch Abstract Aim: There is evidence that regenerative treatment of intra-bony and mandibular class II furcation defects with access flap and an application of an enamel matrix protein derivative (EMD) can result in a clinical benefit compared with access flap alone. The aim of this pilot study was to check if the results of access flap surgery in suprabony defects are improved by additional application of EMD. Material and Methods: Thirty-nine adult subjects with supra-alveolar-type defects were randomly assigned to a test (n=25) and a control group (n=14). Seventy teeth were treated with EMD; 28 teeth were treated by access flap. Probing depth (PD), clinical attachment level and bleeding on probing were evaluated at baseline and after 12 months. Results: PD of the operated teeth was improved in both groups (p<0.001 to p=0.041) but always better in the test group. The attachment gain was 2.72±1.80 mm at sites with an initial PD 7 mm in the test group and 0.78±0.62 mm in the control group (p=0.004). In the test group the mean attachment gain was 0.97±0.92 mm (p<0.001); the mean reduction of PD was 1.55±0.90 mm (p<0.001). Conclusions: The data suggest a significant clinical benefit of supplementary application of EMD during surgical treatment of periodontitis of supra-alveolar pockets, especially in deeper pockets. [source] Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogsJOURNAL OF PERIODONTAL RESEARCH, Issue 1 2003S. Murakami Several growth factors (or cytokines) have been recently investigated for their use as potential therapeutics for periodontal tissue regeneration. The objective of this study was to evaluate periodontal tissue regeneration, including new bone and cementum formation, following topical application of recombinant basic fibroblast growth factor (bFGF, FGF-2) to furcation class II defects. Twelve furcation class II bone defects were surgically created in six beagle dogs, then recombinant bFGF (30 µg/site) + gelatinous carrier was topically applied to the bony defects. Six weeks after application, periodontal regeneration was analyzed. In all sites where bFGF was applied, periodontal ligament formation with new cementum deposits and new bone formation was observed histomorphometrically, in amounts greater than in the control sites. Basic FGF-applied sites exhibited significant regeneration as represented by the new bone formation rate (NBR) (83.6 ± 14.3%), new trabecular bone formation rate (NTBR) (44.1 ± 9.5%), and new cementum formation rate (NCR) (97.0 ± 7.5%). In contrast, in the carrier-only sites, the NBR, NTBR, and NCR were 35.4 ± 8.9%, 16.6 ± 6.2%, and 37.2 ± 15.1%, respectively. Moreover, no instances of epithelial down growth, ankylosis, or root resorption were observed in the bFGF-applied sites examined. The present results indicate that topical application of bFGF can enhance considerable periodontal regeneration in artificially created furcation class II bone defects of beagle dogs. [source] | ||||||||||