Clinical Units (clinical + unit)

Distribution by Scientific Domains


Selected Abstracts


Implementation of electronic signatures and records in a clinical CRO: A case study

QUALITY ASSURANCE JOURNAL, Issue 4 2002
Graham D. Ogg
Abstract Implementation of electronic signatures and records incurs special problems in a specialist Phase I clinical unit where rapid communication, rapid reporting, compliance with applicable regulations and high quality are of paramount importance. Both the business needs and the regulatory compliance issues must be considered in any possible solutions and thus some form of authentication of records and communications is required. In our facility, the requirements of 21 CFR Part 11 did not go far enough regarding authentication and were difficult to implement by medical staff collecting data. Biometric authentication of data entry and encryption of communications appeared to be the best solutions. Copyright © 2002 John Wiley & Sons, Ltd. [source]


Danish dentists' knowledge, attitudes and management of procedural dental pain in children: association with demographic characteristics, structural factors, perceived stress during the administration of local analgesia and their tolerance towards pain

INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY, Issue 3 2005
J. K. RASMUSSEN
Summary., Objective., The aim of the present study was to describe Danish dentists' knowledge of, attitudes towards and management of procedural pain during paediatric dental care, and to assess the importance of demographic characteristics, structural factors, perceived stress during administration of local analgesia and the dentists' own tolerance towards procedural dental pain. Design., A cross-sectional questionnaire study was conducted in Denmark in May 2001. Subjects and methods., The subjects were a random sample of 30% of Danish dentists treating children. Usable information was obtained from 327 (80·3%) of the dentists in the sample. Results., One-quarter of the respondents answered that a 3,5-year-old child could report pain only with uncertainty. More than 80% of the dentists stated that they never compromised on painlessness. Very few agreed to the statement that children forget pain faster than adults. One-third agreed to, or were neutral to, the statement that all restorative care in primary teeth could be performed painlessly using N2O-O2 sedation alone. The majority of the respondents reported using three or more methods to assess the effect of their pain control methods. Almost 90% reported using local analgesia for restorative work ,always' or ,often'. A similar proportion reported using topical analgesia before injection ,always' or ,often'. Administering a mandibular block to preschool children was the procedure perceived as the most stressful (33·6%) pain control method. Demographic factors (gender), structural factors (always working alone and treating 3,5-year-old children daily), perceived stress during the administration of a mandibular block in preschool children and the dentists' own willingness to accept potentially painful dental treatment without local analgesia were associated with knowledge of, attitudes towards and management of procedural dental pain in children. Conclusions., Danish dentists treating children demonstrate concern about procedural dental pain in children. Factors amenable to change via training and reorganization into larger clinical units seem to determine their knowledge of, attitudes towards and management of procedural dental pain in children. [source]


Learning intravenous cannulation: a comparison of the conventional method and the CathSim Intravenous Training System

JOURNAL OF CLINICAL NURSING, Issue 1 2002
KATHERINE KA-PIK CHANG BHSc
,,Intravenous cannulation is a nursing procedure carried out in some clinical units that may induce trauma and discomfort. Nurses should be well prepared before practising the procedure with clients. ,,Conventionally, a plastic arm was used for practice but, with innovative developments in technology, a computer program called the CathSim Intravenous Training System (CathSim ITS) is available for this purpose. This study was conducted to compare the effectiveness of learning using a plastic arm with the CathSim ITS. ,,Twenty-eight nurses were divided into two groups and randomly assigned to the two different methods: plastic arm (control group) or CathSim ITS (experimental group). Both groups were provided with 1 hour of theory input and 2 hours of nursing laboratory work. ,,When the nurses felt ready to practise on clients, their performances were assessed by researchers with an intravenous cannulation qualification using a validated checklist. Prior to the assessment, trait and state anxiety levels were measured using the State-Trait Anxiety Inventory (Hong Kong Chinese adaptation) to check whether anxiety would affect the performance. Following the assessment, a semi-structured interview was conducted to reveal any knowledge acquired through using the selected method. ,,Both the control and CathSim ITS groups demonstrated a high success rate, scoring 100% and 92.86%, respectively, with their first client. ,,The semi-structured interviews revealed that the CathSim ITS group appreciated several features of their assigned method. However, there is room for further development. [source]


Communication effectiveness of nurses working in a variety of settings within one large university teaching hospital in western Japan

NURSING & HEALTH SCIENCES, Issue 4 2002
Misae Ito RN
Abstract This survey study measured the communication effectiveness of 176 nurses working on a variety of clinical units within one large university hospital in western Japan. The vast majority of the nurses demonstrated fair effectiveness in their communication skills. Although some of the nurses did demonstrate slightly higher communication effectiveness scores, few of the nurses' demographic characteristics appeared to influence how well they communicated. The major limitations of the present study were the use of one hospital for data gathering, and the possible lack of cultural sensitivity of the communication questionnaire. [source]


Multiple doses of secretin in the treatment of autism: a controlled study

ACTA PAEDIATRICA, Issue 5 2002
E Sponheim
Dramatic effects on autistic behaviour after repeated injections of the gastrointestinal hormone secretin have been referred in a number of case reports. In the absence of curative and effective treatments for this disabling condition, this information has created new hope among parents. Although controlled studies on the effect of mainly one single dose have not documented any effect, many children still continue to receive secretin. Six children enrolled in a double-blind, placebo-controlled crossover study in which each child was its own control. Human synthetic secretin, mean dose 3.4 clinical units, and placebo were administered intravenously in randomized order every 4th wk, on three occasions each. The measurement instruments were the visual analogue scale (VAS) and the aberrant behaviour checklist (ABC). Statistically significant differences were found for placebo in 3 out of 6 children and for secretin in one child, using parental ratings only (VAS scores). Differences were small and lacked clinical significance, which was in accordance with the overall impression of the parents and teachers and visual inspection of graphs. Conclusion: In this placebo-controlled study, multiple doses of secretin did not produce any symptomatic improvement. [source]