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Chiral Palladium Complexes (chiral + palladium_complex)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Catalytic Enantioselective Fluorination Reactions of ,-Cyano Acetates and ,-Cyanophosphonates Using Chiral Palladium Complexes.

CHEMINFORM, Issue 16 2008
Sun Mi Kim
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Catalytic Enantioselective Fluorination of ,-Cyano Acetates Catalyzed by Chiral Palladium Complexes.

CHEMINFORM, Issue 32 2005
Hye Ran Kim
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Catalytic Asymmetric Addition of ,-Ketoesters to Various Imines by Using Chiral Palladium Complexes.

CHEMINFORM, Issue 28 2005
Yoshitaka Hamashima
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

An Efficient Catalytic Enantioselective Fluorination of ,-Ketophosphonates Using Chiral Palladium Complexes.

CHEMINFORM, Issue 26 2005
Yoshitaka Hamashima
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

PdII -Catalyzed Asymmetric Addition Reactions of 1,3-Dicarbonyl Compounds: Mannich-Type Reactions with N -Boc Imines and Three-Component Aminomethylation

CHEMISTRY - AN ASIAN JOURNAL, Issue 8-9 2008
Yoshitaka Hamashima Dr.
Abstract This paper describes catalytic asymmetric Mannich-type reactions of ,-ketoesters and malonates using chiral palladium complexes. Although readily enolizable, carbonyl compounds are attractive substrates, the use of such compounds as nucleophiles in Mannich-type reactions has not been extensively investigated. In the presence of chiral Pd aqua complexes (2.5,mol,%), ,-ketoesters reacted with various N -Boc imines (Boc=tert -butoxycarbonyl) to afford the desired ,-aminocarbonyl compounds in good yield with high to excellent stereoselectivity (up to 96:4 d.r., 95,99,%,ee in most cases). In these reactions, construction of highly crowded vicinal quaternary and tertiary carbon centers was achieved in one step. A chiral Pd enolate is considered to be the key intermediate. To elucidate the stereoselectivity observed in the reaction, possible transition-state models are discussed, taking into account steric and stereoelectronic effects. Furthermore, this catalytic system was applied to the Mannich-type reaction of malonates with N -Boc imine as well as one-pot classical aminomethylation of ,-ketoesters using benzylamine salt and formalin. The reactions proceeded smoothly, and the corresponding Mannich products were obtained in high yield with moderate to good enantioselectivity. [source]