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Chemical Burn (chemical + burn)
Selected AbstractsChemical burn caused by glycidyl methacrylateCONTACT DERMATITIS, Issue 5 2008Ayako Shimizu No abstract is available for this article. [source] Chemical burn due to trifluoroacetic anhydrideCONTACT DERMATITIS, Issue 4 2002Motonobu Nakamura No abstract is available for this article. [source] Chemical injuries: The Tasmanian burns unit experienceANZ JOURNAL OF SURGERY, Issue 1-2 2003Sophie Ricketts Background: Chemical burns account for relatively few admissions to a burns unit. These injuries, however, deserve separate consideration because of their ability to cause continuing tissue destruction, their potential to cause systemic toxicity and the value of early treatment with copious lavage. Widespread inexperience in the treatment of chemical burns highlights the potential for greater levels of general awareness and knowledge. Methods: A review of 31 patients with chemical injuries admitted to the Tasmanian Burns Unit at the Royal Hobart Hospital (RHH) was carried out for the years 1989,1999. Results: The majority of patients were men aged 20,49 years (mean age: 32 years). Fifty-one per cent of injuries occurred in a domestic and 38% in an industrial setting. The more common aetiological agents were cement (25%), sulphuric acid (16%) and hydrofluoric acid (16%). The upper and lower extremities were involved in all but four patients and the mean total body surface area affected was 3.4%. The mean length of hospital stay was 9 days with a range of 1,30 days. Management of injuries consisted of either surgical or conservative treatment. The former included debridement and split-thickness skin grafting or primary closure and the latter of topical treatment with 1% silver sulfadiazine cream and appropriate dressings. Conclusion: Widespread inexperience in the treatment of chemical injuries highlights the potential for greater levels of knowledge. This is particularly apparent in the early management of these injuries. [source] Human immature dental pulp stem cells share key characteristic features with limbal stem cellsCELL PROLIFERATION, Issue 5 2009B. G. Monteiro Objectives:, Limbal stem cells (LSC) are self-renewing, highly proliferative cells in vitro, which express a set of specific markers and in vivo have the capacity to reconstruct the entire corneal epithelium in cases of ocular surface injury. Currently, LSC transplantation is a commonly used procedure in patients with either uni- or bilateral total limbal stem cells deficiency (TLSCD). Although LSC transplantation holds great promise for patients, several problems need to be overcome. In order to find an alternative source of cells that can partially substitute LSC in cornea epithelium reconstruction, we aimed at investigating whether human immature dental pulp stem cells (hIDPSC) would present similar key characteristics as LSC and whether they could be used for corneal surface reconstruction in a rabbit TLSCD model. Materials:, We used hIDPSC, which co-express mesenchymal and embryonic stem cell markers and present the capacity to differentiate into derivative cells of the three germinal layers. TLSCD was induced by chemical burn in one eye of rabbits. After 30 days, the opaque tissue formed was removed by superficial keratectomy. Experimental group received undifferentiated hIDPSC, while control group only received amniotic membrane (AM). Both groups were sacrificed after 3 months. Results and conclusions:, We have demonstrated, using immunohistochemistry and reverse transcription,polymerase chain reaction, that hIDPSCs express markers in common with LSC, such as ABCG2, integrin ,1, vimentin, p63, connexin 43 and cytokeratins 3/12. They were also capable of reconstructing the eye surface after induction of unilateral TLSCD in rabbits, as shown by morphological and immunohistochemical analysis using human-specific antibodies against limbal and corneal epithelium. Our data suggest that hIDPSCs share similar characteristics with LSC and might be used as a potential alternative source of cells for corneal reconstruction. [source] 2434: Alterations of the lid wiper zone in ocular surface diseaseACTA OPHTHALMOLOGICA, Issue 2010J NEPP Purpose The marginal part of the tarsal conjunctiva forms a lid wiper structure that wipes the ocular surface and distributes the tear film during the blink. It was attempted to investigate whether this region of the upper and lower lid shows specific changes in several kinds of ocular surface diseases. Methods 44 eyes of patients from the outdoor department of the university eye clinic Vienna were observed by slit lamp investigation of the ocular surface, vital staining with fluorescein and lissamin green. It was focused on evaluation of the tarsal conjunctiva including the lid margin and the wiper. Vessel dilatation, teleangiectatic changes and vital staining were each designed in three stages. The patients suffered from inflammation or affections of the lid, the conjunctiva and the cornea including chemical burns, graft versus host disease and injuries Results Compared to normal eyes dilatation of vessels and staining was observed more in patents with inflammations but although in serious affections like chemical burn or injuries. Even in corneal affections changes of vessels were observed. Conclusion Changes of the wiper can be observed in several diseases of the ocular surface and may be a sign of strain in this region. [source] The first keratoprosthesis implantation 1n 1955ACTA OPHTHALMOLOGICA, Issue 2009MF DE LA PAZ Purpose to describe the Barcelona experience with the different types of keratoprosthesis for end-stage cicatricial corneal disease. Methods We present 6 cases showing various types of keratoprosthesis which we have used at the Barraquer Eye Center from the 1950´s up to the present. Results We describe the first keratoprosthesis ever implanted in Spain, on a case of severe chemical burn on a young lady. We implanted a Dorzee acrylic keratoprosthesis in 1955. 5 years later she had extrusion of the prosthesis and superior retinal detachment. The second case describes the Dorzee-Barraquer-Cardona acrylic implant implanted in 1958 on a patient with end-stage glaucoma. Patient had good anatomical retention until his death in 1970. The third case describes the use of the Cardona keratoprosthesis in 1960. Patient had good anatomical and functional results for 8 years until suffering from an acute endophthalmitis. The fourth case demonstrates the expulsion of a Teflon-supported keratoprosthesis designed by Girard. The fifth case describes the first implantation of an osteo-odontokeratoprosthesis designed by Strampelli on a blast injury showing good results for 10 years. The last case shows our experience on the Boston keratoprosthesis which we started using in 2006. Finally, we present our technique of the osteo-odontokeratoprosthesis and a summary of our clinical results from 1970´s to the present. Conclusion Our clinical experience for more than 50 years on the use of keratoprosthesis shows that while the surgical technique, design and post-operative treatment of both biological and non-biological keratoprosthesis have improved thru the years, the anatomical and functional success remains a challenge for the KPro surgeon. [source] Subconjunctival injection of bevacizumab (AvastinŽ) for corneal neovascularizationACTA OPHTHALMOLOGICA, Issue 2009MF DE LA PAZ Purpose to study the effects of subconjunctival injection of Bevacizumab on corneal neovascularization. Methods Prospective interventional case series on 7 eyes of 7 patients who underwent subconjunctival injection with Bevacizumab. The following parameters were studied pre-op, at 1 week, 30, 60 and 90 days post-op: UCVA, BCVA, pachymetry with OCT, slit lamp examination and photographic imaging. Conjunctival impression cytology pre-op at 1 week and 9o days was done and complications were also noted. Results Pre-op diagnoses were: herpetic leucoma (4 eyes), chemical burn (2 eyes), neurotrofic keratopathy (1 eye). An informed off-label consent form prior to procedure was signed. 1.25 mg of subconjunctival Bevacizumab was injected nearest the area affected. Mean preoperative UCVA and BCVA were 0.86 and 0.44 LogMar units, improved to 0.61 and 0.26 LogMar units at 90 days post-op, respectively. Central and peripheral pachymetry improved from 532 and 623 microns pre-op, to 529 and 619 microns at 90 days post-op, respectively. All slit lamp findings and photographic imaging showed a clear regression of superficial and deep stromal corneal vascularization, with clearing of lipid deposits around the affected areas. No toxic effects were noted on conjunctival impression cytology. Conclusion Subconjunctival injection of Bevacizumab is a safe and effective procedure for the regression of superficial and deep corneal neovascularization. It may be a good alternative for patients prior to performing an optical keratoplasty or for those who are poor candidates for the same. [source] Iatrogenic chemical burns associated with tourniquet use and prep solutionANZ JOURNAL OF SURGERY, Issue 10 2009Daniel John Hubik MBBS No abstract is available for this article. [source] Chemical injuries: The Tasmanian burns unit experienceANZ JOURNAL OF SURGERY, Issue 1-2 2003Sophie Ricketts Background: Chemical burns account for relatively few admissions to a burns unit. These injuries, however, deserve separate consideration because of their ability to cause continuing tissue destruction, their potential to cause systemic toxicity and the value of early treatment with copious lavage. Widespread inexperience in the treatment of chemical burns highlights the potential for greater levels of general awareness and knowledge. Methods: A review of 31 patients with chemical injuries admitted to the Tasmanian Burns Unit at the Royal Hobart Hospital (RHH) was carried out for the years 1989,1999. Results: The majority of patients were men aged 20,49 years (mean age: 32 years). Fifty-one per cent of injuries occurred in a domestic and 38% in an industrial setting. The more common aetiological agents were cement (25%), sulphuric acid (16%) and hydrofluoric acid (16%). The upper and lower extremities were involved in all but four patients and the mean total body surface area affected was 3.4%. The mean length of hospital stay was 9 days with a range of 1,30 days. Management of injuries consisted of either surgical or conservative treatment. The former included debridement and split-thickness skin grafting or primary closure and the latter of topical treatment with 1% silver sulfadiazine cream and appropriate dressings. Conclusion: Widespread inexperience in the treatment of chemical injuries highlights the potential for greater levels of knowledge. This is particularly apparent in the early management of these injuries. [source] 2434: Alterations of the lid wiper zone in ocular surface diseaseACTA OPHTHALMOLOGICA, Issue 2010J NEPP Purpose The marginal part of the tarsal conjunctiva forms a lid wiper structure that wipes the ocular surface and distributes the tear film during the blink. It was attempted to investigate whether this region of the upper and lower lid shows specific changes in several kinds of ocular surface diseases. Methods 44 eyes of patients from the outdoor department of the university eye clinic Vienna were observed by slit lamp investigation of the ocular surface, vital staining with fluorescein and lissamin green. It was focused on evaluation of the tarsal conjunctiva including the lid margin and the wiper. Vessel dilatation, teleangiectatic changes and vital staining were each designed in three stages. The patients suffered from inflammation or affections of the lid, the conjunctiva and the cornea including chemical burns, graft versus host disease and injuries Results Compared to normal eyes dilatation of vessels and staining was observed more in patents with inflammations but although in serious affections like chemical burn or injuries. Even in corneal affections changes of vessels were observed. Conclusion Changes of the wiper can be observed in several diseases of the ocular surface and may be a sign of strain in this region. [source] Long-term functional and anatomical results of OOKP and tibial OKP: Barcelona experienceACTA OPHTHALMOLOGICA, Issue 2009MF DE LA PAZ Purpose To report the long-term functional and anatomical results of OOKP and Tibial OKP performed at the Barraquer Eye Center from 1974-2006. Different factors like surgical technique, clinical diagnosis, age and post-operative complications are also analyzed and reported. Methods A retrospective study on 330 eyes of 227 patients who underwent OOKP or tibia OKP was performed. Kaplan Meier survival curves and multivariate analysis using Cox regression model of the different variables mentioned are presented. Results OOKP and Tibia OKP have comparable functional and anatomical results in the long-term. Best long-term functional and anatomical results are for patients with chemical burns, cicatricial trachoma and Stevens-Johnsons/Lyell syndrome. Thermal burns have a higher anatomical retention than other diagnostic categories. Younger patients have better visual prognosis and anatomical retention than older patients. Patients must be warned of the possibility of sight-threatening complications like extrusion of the prosthesis, retinal detachment and glaucoma. Conclusion Our more than 35 years experience with biological keratoprosthesis using the OOKP and the tibia OKP shows that the two techniques are comparable. Certain variables like clinical diagnosis, age and post-operative complications affect the anatomical and functional results in the long-term. [source] MOOKP clinical results and IndicationsACTA OPHTHALMOLOGICA, Issue 2009G FALCINELLI Purpose To demonstrate which are the reasons that permit by the modified osteo-odonto-keratoprosthesis (Mookp) technique to obtain in 275 blind eyes,with a basic pathology where 42% of eyes were dry,and 32% had severe physical/chemical burns,excellent anatomical and functional results. Methods Tables are shown which put into evidence the best visual acuity obtained in the 275 eyes affected by corneal blindness,operated by the Mookp technique from 1973 to 2008, with a 36 years causistry,with a very long follow-up. Results 275 blind eyes. Best Visual Acuity recovered, between 10/10 and 5/10 in 80.25% of operated eyes, excellent for any working activity,( best visual acuity recovered), between 10/10 and 2/10 in 91,20%, useful for any activity. Final V.A., between 10/10 and 5/10 in 67,68%, and between 10/10 and 2/10 in 78,11%- Conclusion The reasons for these excellent results are due to the biological properties of this Kpro invented by Strampelli and to the modifications made by Falcinelli. The indications for this technique are all those types of corneal blindness not treatable by penetrating keratoplasty. [source] | ||||||||||