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Kinds of Charge Terms modified by Charge Selected AbstractsGenome-wide association studies of cardiovascular risk factors: design, conduct and interpretationJOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 2009J. C. BIS Summary., Relying on known biology, candidate-gene studies have been only modestly successful in identifying genetic variants associated with cardiovascular risk factors. Genome-wide association (GWA) studies, in contrast, allow broad scans across millions of loci in search of unsuspected genetic associations with phenotypes. The large numbers of statistical tests in GWA studies and the large sample sizes required to detect modest-sized associations have served as a powerful incentive for the development of large collaborative efforts such as the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium [1]. This article uses published data on three phenotypes, fibrinogen, uric acid, and electrocardiographic QT interval duration, from the CHARGE Consortium to describe several methodologic issues in the design, conduct, and interpretation of GWA studies, including the use of imputation and the need for additional genotyping. Even with large studies, novel genetic loci explain only a small proportion of the variance of cardiovascular phenotypes. [source] 1H chemical shifts in NMR: Part 22,,Prediction of the 1H chemical shifts of alcohols, diols and inositols in solution, a conformational and solvation investigationMAGNETIC RESONANCE IN CHEMISTRY, Issue 8 2005Raymond J. Abraham Abstract The 1H NMR spectra of a number of alcohols, diols and inositols are reported and assigned in CDCl3, D2O and DMSO- d6 (henceforth DMSO) solutions. These data were used to investigate the effects of the OH group on the 1H chemical shifts in these molecules and also the effect of changing the solvent. Inspection of the 1H chemical shifts of those alcohols which were soluble in both CDCl3 and D2O shows that there is no difference in the chemical shifts in the two solvents, provided that the molecules exist in the same conformation in the two solvents. In contrast, DMSO gives rise to significant and specific solvation shifts. The 1H chemical shifts of these compounds in the three solvents were analysed using the CHARGE model. This model incorporates the electric field, magnetic anisotropy and steric effects of the functional group for long-range protons together with functions for the calculation of the two- and three-bond effects. The long-range effect of the OH group was quantitatively explained without the inclusion of either the CO bond anisotropy or the COH electric field. Differential , and , effects for the 1,2-diol group needed to be included to obtain accurate chemical shift predictions. For DMSO solution the differential solvent shifts were calculated in CHARGE on the basis of a similar model, incorporating two-bond, three-bond and long-range effects. The analyses of the 1H spectra of the inositols and their derivatives in D2O and DMSO solution also gave the ring 1H,1H coupling constants and for DMSO solution the CHOH couplings and OH chemical shifts. The 1H,1H coupling constants were calculated in the CHARGE program by an extension of the cos2, equation to include the orientation effects of electronegative atoms and the CHOH couplings by a simple cos2, equation. Comparison of the observed and calculated couplings confirmed the proposed conformations of myo -inositol, chiro -inositol, quebrachitol and allo -inositol. The OH chemical shifts were also calculated in the CHARGE program. Comparison of the observed and calculated OH chemical shifts and CH. OH couplings suggested the existence of intramolecular hydrogen bonding in a myo -inositol derivative. Copyright © 2005 John Wiley & Sons, Ltd. [source] 1H chemical shifts in NMR.MAGNETIC RESONANCE IN CHEMISTRY, Issue 1 2005Part 2, Prediction of the 1H chemical shifts of molecules containing the ester group: a modelling, ab initio investigation Abstract The 1H NMR spectra of 24 compounds containing the ester group are given and assigned. These data were used to investigate the effect of the ester group on the 1H chemical shifts in these molecules. These effects were analysed using the CHARGE model, which incorporates the electric field, magnetic anisotropy and steric effects of the functional group for long-range protons together with functions for the calculation of the two- and three-bond effects. The effect of the ester electric field was given by considering the partial atomic charges on the three atoms of the ester group. The anisotropy of the carbonyl group was reproduced with an asymmetric magnetic anisotropy acting at the midpoint of the carbonyl bond with values of ,,parl and ,,perp of 10.1 × 10,30 and ,17.1 × 10,30 cm3 molecule,1. An aromatic ring current (=0.3 times the benzene ring current) was found to be necessary for pyrone but none for maleic anhydride. This result was confirmed by GIAO calculations. The observed 1H chemical shifts in the above compounds were compared with those calculated by CHARGE and the ab initio GIAO method (B3LYP/6,31G**). For the 24 compounds investigated with 150 1H chemical shifts spanning a range of ca 10 ppm, the CHARGE model gave an excellent r.m.s. error (obs , calc) of <0.1 ppm. The GIAO calculations gave a very reasonable r.m.s. error of ca 0.2 ppm although larger deviations of ca 0.5 ppm were observed for protons near to the electronegative atoms. The accurate predictions of the 1H chemical shifts given by the CHARGE model were used in the conformational analysis of the vinyl esters methyl acrylate and methyl crotonate. An illustration of the use of the CHARGE model in the prediction of the 1H spectrum of a complex organic molecule (benzochromen-6-one) is also given. Copyright © 2004 John Wiley & Sons, Ltd. [source] Taking CHARGE: A self-management program for women following breast cancer treatmentPSYCHO-ONCOLOGY, Issue 9 2005Bernadine Cimprich The purpose of the study was to develop and evaluate Taking CHARGE, a self-management intervention designed to facilitate successful transitions to survivorship after breast cancer treatment. The Taking CHARGE intervention involves a two-pronged approach building on self-regulation principles to (1) equip women with self-management skills to address concerns following breast cancer treatment, and (2) provide information about common survivorship topics. The program involved four intervention contacts, two small group meetings and two individualized telephone sessions, delivered by nurse/health educators. This paper focuses on the process evaluation findings from a preliminary test of the Taking CHARGE intervention conducted with 25 women, aged 34,66 years, completing breast cancer treatment, who were randomly assigned to the intervention group. The process evaluation was conducted to obtain systematic information about the relevance and usefulness of the self-regulation approach, informational aspects, and program delivery. The findings indicated that intervention group participants found the Taking CHARGE program to be timely, relevant, and to have high utility in dealing with concerns that exist following breast cancer treatment. The process evaluation findings provide early evidence of the usefulness of the Taking CHARGE intervention for successful transition to survivorship following breast cancer treatment. Copyright © 2005 John Wiley & Sons, Ltd. [source] CHARGE syndrome as unusual cause of hypogonadism: endocrine and molecular evaluationANDROLOGIA, Issue 5 2010L. Foppiani Summary Coloboma, heart defect, atresia choanae, retarded growth and development, genital hypoplasia, ear anomalies (CHARGE) syndrome is a genetic syndrome in which hypogonadism is a frequent feature. A causative mutation within the chromodomain helicase DNA-binding protein-7 gene, which plays an important role in the embryonic development, is present in 2/3 of affected patients. We describe the clinical, hormonal and molecular characteristics of a young man from Ecuador who was diagnosed as having CHARGE syndrome at an adult age. The patient showed several phenotypic features of the syndrome, associated with a prepubertal state and cryptorchidism; hypogonadotrophic hypogonadism with undetectable testosterone levels not responsive to hCG testing and severe osteoporosis were ascertained. Molecular evaluation of the CHD7 gene showed the novel frameshift truncating heterozygous mutation p.Tyr1046Glyfs*23 in exon 12. Magnetic resonance imaging revealed mild hypoplasia of the pituitary gland and hypoplasia of the posterior cranial fossa. Parenteral testosterone therapy led to sexual development over time and, in combination with diphophonate therapy and calcium,vitamin D supplementation, significantly improved bone mineralisation. Early proper hormonal treatment of hypogonadism in patients with complex genetic syndromes is important to achieve normal sexual maturation, improve quality of life and avoid significant comorbidities, such as osteoporosis. [source] THE TEN COMMANDMENTS FOR OPTIMIZING VALUE-AT-RISK AND DAILY CAPITAL CHARGESJOURNAL OF ECONOMIC SURVEYS, Issue 5 2009Michael McAleer Abstract Credit risk is the most important type of risk in terms of monetary value. Another key risk measure is market risk, which is concerned with stocks and bonds, and related financial derivatives, as well as exchange rates and interest rates. This paper is concerned with market risk management and monitoring under the Basel II Accord, and presents Ten Commandments for optimizing value-at-risk (VaR) and daily capital charges, based on choosing wisely from (1) conditional, stochastic and realized volatility; (2) symmetry, asymmetry and leverage; (3) dynamic correlations and dynamic covariances; (4) single index and portfolio models; (5) parametric, semi-parametric and non-parametric models; (6) estimation, simulation and calibration of parameters; (7) assumptions, regularity conditions and statistical properties; (8) accuracy in calculating moments and forecasts; (9) optimizing threshold violations and economic benefits; and (10) optimizing private and public benefits of risk management. For practical purposes, it is found that the Basel II Accord would seem to encourage excessive risk taking at the expense of providing accurate measures and forecasts of risk and VaR. [source] Enforcement of environmental charges: some economic aspects and evidence from the German Waste Water ChargeENVIRONMENTAL POLICY AND GOVERNANCE, Issue 5 2001Professor Dr Erik Gawel Enforcement problems are usually analysed with respect to command-and-control measures of environmental regulation. The recognition that any environmental policy instrument entails an enforcement problem in principle is basic to a comparative analysis of enforcement effects. This paper deals with the comparative enforcement effects of charges: How does enforcement of a charge function? Which problems occur particularly in the enforcement of charges? Could enforcement be facilitated by a specific construction of charge laws? Are economic concepts of charge enforceable at all, and if so, under what conditions? Are charges more readily enforceable than other instruments? Therefore, some economic theory assessments of enforcement processes are presented first. In a third part, the paper sheds light on the practical experience made with the enforcement of the German Waste Water Charge. It is argued that the well worn thesis of an enforcement-friendly ,self-control' of market instruments is based on unrealistic assumptions. Whether against this background enforcement of environmental policy can be facilitated by an increased application use of charges must be viewed sceptically in an overall assessment of the problematic. Moreover, the transition from allocative control tasks to fiscal environmental charges may well be a symptom of rather than a contribution to the solution of the political and administrative crisis of enforcement. Especially for charges, the crucial question seems to be the political implementation rather than concrete enforcement by local authorities. Copyright © 2001 John Wiley & Sons, Ltd. and ERP Environment [source] An Atropo-Stereogenic Diphosphane Ligand with a Proximal Cationic Charge: Specific Catalytic Properties of a Palladium Complex ThereofEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 19 2008Nathalie Debono Abstract A class of cationic diphosphane ligands combining phosphane and amidiniophosphane moieties is illustrated on the N -methyl,N -naphthylbenzimidazolium framework. The palladium(II) complex thereof is described and compared to the corresponding complex of the analogous neutral diphosphane. Contrary to first-level expectations, the N2C,P and N2CP,Pd bonds in the cationic diphosphane complex are not longer than those occurring in its neutral counterpart. In the cationic ligand, the proximal positive charge is indeed conjugated to one phosphanyl group, and the coordination scheme is tentatively interpreted by resonance of the phosphane,metal dative bond (+N2C,P:,[Pd]) with a carbene,phosphenium dative bond (N2C:,[+P:,Pd]). Despite this peculiar structural feature, the electronic , donation (vs. , acceptation) towards the palladium centre remains lowered in the cationic ligand. This specific property can be a priori valuable in a catalytic process where oxidative addition is not the limiting step. It is indeed shown that although the neutral complex is more active in Suzuki coupling reactions, the cationic complex is more active in Sonogashira-type coupling reactions involving predissociated halide substrates, namely an acyl chloride. These likely atropo-chiral ligands deserve to be resolved for application in asymmetric catalysis.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] Outlying Charge, Stability, Efficiency, and Algorithmic Enhancements in the Quantum-Mechanical Solvation Method, COSab-GAMESSHELVETICA CHIMICA ACTA, Issue 12 2003Laura In this work, we present algorithmic modifications and extensions to our quantum-mechanical approach for the inclusion of solvent effects by means of molecule-shaped cavities. The theory of conductor-like screening, modified and extended for quantum-mechanical techniques, serves as the basis for our solvation methodology. The modified method is being referred to as COSab-GAMESS and is available within the GAMESS package. Our previous work has emphasized the implementation of this model by way of a distributed multipole approach for handling the effects of outlying charge. The method has been enabled within the framework of open- and closed-shell RHF and MP2. In the present work, we present a) a second method to handle outlying charge effects, b) algorithmic extensions to open- and closed-shell density-functional theory, second-derivative analysis, and reaction-path following, and c) enhancements to improve performance, convergence, and predictability. The method is now surtable for large molecular systems. New features of the enhanced continuum model are highlighted by means of a set of neutral and charged species. Computations on a series of structures with roughly the same molecular shape and volume provides an evaluation of cavitation effects. [source] Charge and Mass Transfer Across the Metal/Solution InterfaceISRAEL JOURNAL OF CHEMISTRY, Issue 3-4 2008Eliezer Gileadi Electrode reactions are characterized by charge transfer across the interface. The charge can be carried by electrons or by ions. It is shown here that when both mass and charge cross the interface, the charge must be carried by the ionic species, not by the electrons, as a result of the very large difference in the time scale for electron and ion transfer. A prime example of charge transfer by ions is metal deposition. It is proposed that ion transfer occurs by migration of the ions across the interface, under the influence of the high electrostatic field in the double layer. The rate constants observed for metal deposition are comparable to those for outer-sphere charge transfer. These unexpectedly high rate constants for metal deposition are explained by a model in which removal of the solvation shell and reduction of the effective charge on the metal ion occur in many small steps, and a make-before-break mechanism exists, which lowers the total Gibbs energy of the system as it moves along the reaction coordinate from the initial to the final state. [source] Leading the Charge: Media, Elites, and the Use of Emotion in Stimulating Rally Effects in WartimeJOURNAL OF COMMUNICATION, Issue 3 2010Sean Aday This study examines the relationship between media coverage, elite cues, and emotion in shaping public opinion about use of force. It utilizes data across three time periods: an experiment conducted in early 2005 during the Iraq War, National Election Studies data collected during the 2004 U.S. Presidential election, and NES data collected shortly after the U.S./coalition victory in the 1991 Gulf War. The study finds that contrary to conventional wisdom, media exert less influence on public opinion when they report negative or controversial news than when they reflect elite consensus and/or patriotic fervor. However, their importance is likely dependent upon the state of elite opinion, and thus media are best thought of as intervening variables between policymakers and the public. [source] Microbial biomass and activity under oxic and anoxic conditions as affected by nitrate additionsJOURNAL OF PLANT NUTRITION AND SOIL SCIENCE, Issue 1 2006Jens Dyckmans Abstract Soil microbial activity, biomass, and community structure were examined during the transition from oxic to anoxic conditions after the addition of glucose and with or without nitrate addition. In two sets of treatments, samples were incubated for up to 35 d in closed ampoules either aerobically until oxygen was depleted or anoxically throughout the experiment. Heat-flow rate was monitored to indicate microbial activity. Microbial biomass and community structure were measured by adenylate and phospholipid fatty acid (PFLA) content, and adenylate energy charge (AEC) was used to monitor the physiological status of the microbial biomass. Microbial activity was highest under oxic conditions and abruptly decreased under anoxic conditions. Activity peaks were observed after about 9 d of anoxic conditions probably triggered by increased nutrient availability from dying microbial biomass, but these peaks were smaller after initial oxic incubation or nitrate addition. Microbial biomass was unchanged under oxic conditions but decreased under anoxic conditions. Most surviving microbes switched into dormancy. Changes in the microbial-population structure were small and occurred only after 9 d of anoxic incubation. The results show that the nutrient status and the availability of electron acceptors such as nitrate were important factors ruling the direction and the extent of shifts in the microbial activity and community structures due to anoxic conditions. Mikrobielle Biomasse und Aktivität unter oxischen und anoxischen Bedingungen in Abhängigkeit von Nitratzugabe Untersucht wurden Aktivität, Menge und Zusammensetzung der mikrobiellen Biomasse im Übergang von oxischen zu anoxischen Bedingungen in Bodenproben nach Zugabe von Glucose sowie mit und ohne Nitratzugabe. Bodenproben wurden bis zu 35 Tage in geschlossenen Gefäßen entweder oxisch bis zum Verbrauch des Sauerstoffs oder von Beginn an anoxisch inkubiert. Dabei wurde der Wärmefluss als Indikator für die mikrobielle Aktivität gemessen. Menge und Zusammensetzung der mikrobiellen Biomasse wurden über die Gehalte an Adenylaten und Phospholipidfettsäuren bestimmt. Der ,Adenylate Energy Charge" (AEC) wurde genutzt, um den physiologischen Status der mikrobiellen Biomasse zu bestimmen. Die mikrobielle Aktivität war unter oxischen Bedingungen am höchsten und ging unter anoxischen Bedingungen drastisch zurück. Aktivitätspeaks wurden nach etwa 10 Tagen anoxischer Inkubation beobachtet und waren vermutlich verursacht durch ein erhöhtes Nährstoffangebot aus der abgestorbenen Biomasse. Diese Peaks waren geringer nach vorhergehender oxischer Inkubation bzw. nach Nitratzugabe. Die mikrobielle Biomasse war unter oxischen Bedingungen unverändert, nahm aber unter anoxischen Bedingungen ab, die meisten überlebenden Mikroben waren dabei dormant. Änderungen in der mikrobiellen Gesellschaft traten nur in geringem Umfang und erst nach 9 Tagen anoxischer Inkubation auf. Unsere Ergebnisse zeigen, dass das Nährstoffangebot und die Verfügbarkeit von Elektronenakzeptoren wie z.,B. Nitrat wichtige Steuergrößen für Richtung und Ausmaß von Veränderungen in der mikrobiellen Aktivität und Zusammensetzung unter anoxischen Bedingungen sind. [source] A Charge We Have to Keep.JOURNAL OF POLICY AND PRACTICE IN INTELLECTUAL DISABILITIES, Issue 2 2005A Road Map to Personal, Economic Freedom for Persons with Intellectual Disabilities in the 21st Century [source] "Charge transfer" polymerization,and the absence thereof!JOURNAL OF POLYMER SCIENCE (IN TWO SECTIONS), Issue 13 2001H. K. Hall Abstract Mechanisms for "charge-transfer" spontaneous polymerizations and cycloadditions between electron-rich olefins and electron-poor olefins were reviewed. As for propagation, literature proposals involving charge-transfer complexes were rejected. Instead, alternating copolymerization is ascribed to polar effects in free-radical reactions. As for spontaneous initiation, literature proposals involving charge-transfer complexes, with or without proton transfer, were rejected. Instead, the initiating species is postulated to be a tetramethylene zwitterion biradical, which may initiate either ionic homopolymerization or free-radical copolymerization. A new hypothesis proposes that any interaction that brings vinyl monomers close together may facilitate tetramethylene formation and spontaneous polymerization. These interactions include Coulombic, acid,base, hydrophobic,hydrophilic and templating,tethering interactions. © 2001 John Wiley & Sons, Inc. J Polym Sci Part A: Polym Chem 39: 2069,2077, 2001 [source] Influence of Solute Charge and Hydrophobicity on Partitioning and Diffusion in a Genetically Engineered Silk-Elastin-Like Protein Polymer HydrogelMACROMOLECULAR BIOSCIENCE, Issue 10 2010Adam A. Dinerman Abstract The influence of solute hydrophobicity and charge on partitioning and diffusion in physically crosslinked networks of a genetically engineered SELP polymer was investigated. A series of fluorescent dyes were used to assess the impact of solute charge and hydrophobicity on release behavior. The mechanism of solute release from the SELP hydrogel appeared to vary as a function of dye hydrophobicity. The extent of FITC attachment to amine-terminated G4 dendrimers influenced SELP hydrogel partitioning more than dendrimer diffusion properties. Results suggest the possibility of controlling solute release from SELP hydrogels by modifying the hydrophobicity and surface charge of drugs and drug/polymer conjugates as well as the possibility of "designing-in" solute-specific interactions. [source] HAS PSYCHOLOGY DEBUNKED CONCEPTUAL ANALYSIS?METAPHILOSOPHY, Issue 1 2006PER SANDIN Abstract: The philosophical method of conceptual analysis has been criticised on the grounds that empirical psychological research has cast severe doubt on whether concepts exist in the form traditionally assumed, and that conceptual analysis therefore is doomed. This objection may be termed the Charge from Psychology. After a brief characterisation of conceptual analysis, I discuss the Charge from Psychology and argue that it is misdirected. [source] ,Captain of all these men of death': The history of tuberculosis in nineteenth and twentieth century Ireland and No Charge , No undressing: Fronting up for good healthNURSING INQUIRY, Issue 4 2006Stephanie Kirby [source] 12 Walker: The General Leads the ChargeAMERICAN JOURNAL OF ECONOMICS AND SOCIOLOGY, Issue 5 2003STEVEN B. CORD First page of article [source] Thermal Blending Time Associated With a Charge of Hot Particles Added to a Fluidized Bed of Uniform TemperatureTHE CANADIAN JOURNAL OF CHEMICAL ENGINEERING, Issue 3 2006W. A. Brown Abstract The process of heat transfer between particles in a fluidized bed is important for many industrial fluidized bed processes. The problem associated with studying this phenomenon is the confounding effect of particle mixing on heat transfer. The work described here was undertaken to describe the process in which heat is added to a fluid bed process by adding a hot charge of particles to a colder fluidized bed. The rate of heat transfer in this instance can have a significant impact on performance of the fluid bed process, depending upon its application. Both the method of analysis and the results of the work are applicable to other fluidized bed processes, particularly those associated with the thermal upgrading of heavy oil. The method of data analysis, based on binomial statistics, allowed useful data to be extracted from a complex system without the need for a large number of experiments. The analysis also allowed for some assessment of the relative importance of mixing and heat transfer, which has not been possible with other approaches. The results of the experiments were further explored using a bubbling bed model that incorporated both heat transfer and solids mixing. This allowed for the formation of a conceptual model, validated by the experimentation, that explains the relative functions of the two transfer processes in the dispersion of heat from a hot charge of particles to the bulk of a fluidized bed. Le procédé de transfert de chaleur entre les particules dans un lit fluidisé joue un rôle important dans de nombreux procédés industriels en lit fluidisé. Le problème associé à l'étude de ce phénomène est l'effet de confusion du mélange des particules sur le transfert de chaleur. Le travail décrit ici a été entrepris pour décrire le procédé dans lequel un lit fluidisé est chauffé en ajoutant une charge chaude de particules à lit fluidisé plus froid. Le taux de transfert de chaleur dans cet exemple peut avoir un impact significatif sur la performance du procédé en lit fluidisé, selon son application. Autant la méthode d'analyse que les résultats du travail sont applicables à d'autres procédés de lits fluidisés, en particulier ceux associés à la valorisation thermique de l'huile lourde. La méthode d'analyse des données, basée sur des statistiques binomiales, permet d'extraire des résultats utiles d'un système complexe sans avoir besoin de beaucoup d'expériences. L'analyse permet également de jauger l'importance relative du mélange et du transfert de chaleur, ce qui n'a pas été possible avec d'autres approches. Les résultats des expériences ont été analysés de manière plus approfondie au moyen d'un modèle à lit bouillonnant qui incorpore à la fois le transfert de chaleur et le mélange de solides. Ceci permet l'établissement d'un modèle conceptuel validé, qui explique les fonctions relatives des deux procédés de transfert dans la dispersion de la chaleur à partir d'une charge chaude de particules dans le coeur d'un lit fluidisé. [source] Creating a Shared Formulary in 7 Critical Access HospitalsTHE JOURNAL OF RURAL HEALTH, Issue 3 2010Douglas S. Wakefield PhD Abstract Purpose: This paper reports a case study of 7 Critical Access Hospitals' (CAH) and 1 rural referral hospital's successful collaboration to develop a shared formulary. Methods: Study methods included document reviews, interviews with key informants, and use of descriptive statistics. Findings: Through a systematic review and decision process, CAH formularies ranging in size from 667 to 1,351 items were compared, rationalized, and consolidated resulting in an 803-item shared formulary. While the individual CAHs were generally expected to list and stock the same 803 items in the shared formulary's pharmacy information system, they could individually determine the amount to be stocked for each item, as well as stock additional items not included on the shared formulary to reflect local provider preferences and services provided. Final stocked formulary items ranged from 592 to 786 items among the 7 CAHs. Major challenges and lessons learned in the course of developing a shared formulary related to: Meeting Logistics, Facilitator to Manage the Process, Organizing the Review Process, Management Support, Stakeholder Participation, Working Collaboratively, Decision-Making Process, Clarity of Charge, Meeting the Needs of Unique Services, Communicating with Providers, and Adjusting to a Shared Formulary. Conclusions: Collaborating in the development of a shared formulary allows for a greater range of decision-making expertise, shared workload, and an improved formulary. An organized and well-managed group decision-making process is essential to a successful collaboration. [source] Catanionic Tubules with Tunable Charge,ANGEWANDTE CHEMIE, Issue 37 2010Nicola Manghisi Dr. Positiv und negativ in der Waage: Ein neuartiges Verhalten im Bereich katanionischer Systeme wurde in Lösungen von anionischen und kationischen Formen starrer, ungewöhnlicher Amphiphile beobachtet. Verdünnte wässrige Mischungen von anionischen und kationischen Gallensäure-Derivaten bilden katanionische Röhren, deren Ladung durch das Molverhältnis der Tenside in der Mischung bestimmt wird. [source] Patterning of Electrostatic Charge on Electrets Using Hot Microcontact Printing,ANGEWANDTE CHEMIE, Issue 36 2009Dan Zhao Heiße Sache: Ein topographisch gemusterter Poly(dimethylsiloxan)(PDMS)-Stempel wird auf 50,220,°C erhitzt und nutzt dann diese Wärmeenergie als ,Tinte" für ein Mikrokontaktdrucken (,CP), indem er chemisches Vernetzen, Zersetzen oder andere Umwandlungen auslöst. Die Heiß-,CP-Technik kann Muster aus elektrostatischen Ladungen auf Elektreten durch selektive thermisch stimulierte Entladung (TSD, siehe Bild) oder Depolarisierung erzeugen. [source] ChemInform Abstract: Density Functional Theory Studies of Spin, Charge, and Orbital Ordering in YBaT2O5 (T: Mn, Fe, Co).CHEMINFORM, Issue 40 2008R. Vidya Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Spin, Charge, and Orbital Ordering in the B-Site Diluted Manganates La2-xSrxGaMnO6.CHEMINFORM, Issue 14 2002P. D. Battle Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Ion and pH Sensing with Colloidal Nanoparticles: Influence of Surface Charge on Sensing and Colloidal PropertiesCHEMPHYSCHEM, Issue 3 2010Feng Zhang Dr. Abstract Ion sensors based on colloidal nanoparticles (NPs), either as actively ion-sensing NPs or as nanoscale carrier systems for organic ion-sensing fluorescent chelators typically require a charged surface in order to be colloidally stable. We demonstrate that this surface charge significantly impacts the ion binding and affects the read-out. Sensor read-out should be thus not determined by the bulk ion concentration, but by the local ion concentration in the nano-environment of the NP surface. We present a conclusive model corroborated by experimental data that reproduces the strong distance-dependence of the effect. The experimental data are based on the capability of tuning the distance of a pH-sensitive fluorophore to the surface of NPs in the nanometer (nm) range. This in turn allows for modification of the effective acid dissociation constant value (its logarithmic form, pKa) of analyte-sensitive fluorophores by tuning their distance to the underlying colloidal NPs. [source] The Effect of Seatbelt Use on Injury Patterns, Disposition, and Hospital Charges for EldersACADEMIC EMERGENCY MEDICINE, Issue 12 2002Andrew Coley MD Objective: To study the relationships between seatbelt use and injury patterns, hospital charges, morbidity, and mortality in elder motor vehicle crash victims. Methods: A retrospective review of individuals at least 65 years old presenting to an urban emergency department (ED) after a motor vehicle crash. Results: Over a two-year period, 339 patients had documentation of seatbelt use or non-use at the time of the crash. Of these, 241 (71%) patients had been wearing a seatbelt and 98 (29%) had not. Elders not using seatbelts were more likely to require hospitalization (29% unbelted vs. 17% belted) and had a higher mortality rate. Injury patterns were different in the two groups. Emergency department charges were significantly different between belted and unbelted elders ($351 vs. $451, p = 0.01) and head computed tomography (CT) utilization was higher in the unbelted group (25.6% vs 12.7%, p = 0.005). Conclusions: Improved seatbelt compliance in elders can reduce injuries, hospitalization rates, ED charges, and mortality resulting from motor vehicle crashes. [source] Manipulating Charges and Excitons within a Single-Host System to Accomplish Efficiency/CRI/Color-Stability Trade-off for High-Performance OWLEDsADVANCED MATERIALS, Issue 29 2009Qi Wang No abstract is available for this article. [source] Manipulating Charges and Excitons within a Single-Host System to Accomplish Efficiency/CRI/Color-Stability Trade-off for High-Performance OWLEDsADVANCED MATERIALS, Issue 23 2009Qi Wang To reveal superior efficiency/CRI/color-stability trade-off for OWLED fabrications, a single-host concept is proposed in which the primary-color emitters are rationally arranged to render two types (R,G,B and RG,B) of OWLEDs with ultrahigh electroluminescence performance. Comprehensive experimental and theoretical evidence reveal that careful management of charges and excitons is the key to the realization of such high performances. [source] Hospital Charges Attributable to a Primary Diagnosis of Infectious Diseases in Older Adults in the United States, 1998 to 2004JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 6 2008Aaron T. Curns MPH OBJECTIVES: To describe total and average hospital charges associated with infectious disease (ID) hospitalizations and specific ID categories and to estimate ID hospitalization rates in adults aged 65 and older in the United States from 1998 through 2004. DESIGN: Retrospective analysis of hospital discharge data obtained from the Nationwide Inpatient Sample for 1998 through 2004. SETTING: United States. PATIENTS: Older adults hospitalized in the United States from 1998 through 2004. MEASUREMENTS: Hospital charges and hospitalization rates for IDs described according to year, age group, sex, U.S. Census region, and ID category. Charges for non-ID hospitalizations were also described. Hospital charges were adjusted for inflation. RESULTS: From 1998 through 2004, total charges for ID hospitalizations exceeded $261 billion and accounted for 13% of all hospital charges for older adults. Total charges for ID hospitalizations increased from $31.4 billion in 1998 to $45.7 billion in 2004. The average annual ID hospital charge was lower than the average annual non-ID hospital charge during the study period ($21,342 vs $22,787, P<.001). The average annual rate for ID hospitalizations was 503 per 10,000 older adults, which remained stable during the study period. CONCLUSION: The total charges for ID hospitalizations and for all hospitalizations in older adults in the United States increased 45% and nearly 40%, respectively, during the 7-year study period, whereas the population of older adults grew by only 5%. Sustained increases of such magnitude will have major implications for the U.S. healthcare system as it prepares for the more than doubling of the older U.S. adult population during the first 30 years of this century. [source] Liberia: Graft Charges DroppedAFRICA RESEARCH BULLETIN: ECONOMIC, FINANCIAL AND TECHNICAL SERIES, Issue 4 2009Article first published online: 4 JUN 200 No abstract is available for this article. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||||||||