Acoustic

Distribution by Scientific Domains
Distribution within Life Sciences

Terms modified by Acoustic

  • acoustic analysis
  • acoustic cavitation
  • acoustic character
  • acoustic characteristic
  • acoustic communication
  • acoustic cue
  • acoustic emission
  • acoustic energy
  • acoustic environment
  • acoustic feature
  • acoustic field
  • acoustic measurement
  • acoustic microscopy
  • acoustic mode
  • acoustic noise
  • acoustic parameter
  • acoustic phonon
  • acoustic power
  • acoustic property
  • acoustic recording
  • acoustic scattering
  • acoustic signal
  • acoustic stimulation
  • acoustic stimulus
  • acoustic structure
  • acoustic survey
  • acoustic tag
  • acoustic telemetry
  • acoustic transmitters
  • acoustic variation
  • acoustic wave

  • Selected Abstracts


    MECHANICAL,ACOUSTIC AND SENSORY EVALUATIONS OF CORNSTARCH,WHEY PROTEIN ISOLATE EXTRUDATES

    JOURNAL OF TEXTURE STUDIES, Issue 4 2007
    E.M. CHENG
    ABSTRACT The mechanism relating sensory perception of brittle food foams to their mechanical and acoustic properties during crushing was investigated. Cornstarch was extruded with four levels of whey protein isolate (0, 6, 12 and 18%) and two levels of in-barrel moisture (23 and 27%). Hardness, fracturability and roughness of mass were three main sensory attributes that varied substantially between products. High correlations (r = 0.841,0.998) were observed between sensory attributes and instrumentally determined mechanical properties, including crushing force (11.2,57.9 N) and crispness work (4.6,75.8 N·mm). Based on acoustic data obtained during instrumental crushing, time-domain signal processing and a novel voice recognition technique utilizing frequency spectrograms were successfully employed for understanding the differences in the sensory properties of various products. Microstructure features, including average cell diameter (1.00,2.94 mm), average wall thickness (0.04,0.27 mm) and cell number density (7,193 cell/cm3), were characterized noninvasively using X-ray microtomography, and proved to be critical in relating sensory perception of the cellular extrudates to their mechanical,acoustic signatures. PRACTICAL APPLICATIONS The sensory perception of crispy and crunchy food products is primarily a function of their mechanical response and emission of sounds during fracture. The current study was focused on understanding these relationships in the context of brittle extruded foods. The mechanical,acoustic techniques outlined in this study have the potential of reducing the time, costs and subjectivity involved in evaluation of new foods by human panels, and can be a useful tool in the overall product development cycle. These techniques need not be limited only to food systems, as properties of any rigid, fracturable material can be characterized based on its mechanical,acoustic signature. [source]


    Ontogeny of Acoustic and Feeding Behaviour in the Grey Gurnard, Eutrigla gurnardus

    ETHOLOGY, Issue 3 2005
    M. Clara P. Amorim
    Although sound production in teleost fish is often associated with territorial behaviour, little is known of fish acoustic behaviour in other agonistic contexts such as competitive feeding and how it changes during ontogeny. The grey gurnard, Eutrigla gurnardus, frequently emits knock and grunt sounds during competitive feeding and seems to adopt both contest and scramble tactics under defensible resource conditions. Here we examine, for the first time, the effect of fish size on sound production and agonistic behaviour during competitive feeding. We have made sound (alone) and video (synchronized image and sound) recordings of grey gurnards during competitive feeding interactions. Experimental fish ranged from small juveniles to large adults and were grouped in four size classes: 10,15, 15,20, 25,30 and 30,40 cm in total length. We show that, in this species, both sound production and feeding behaviour change with fish size. Sound production rate decreased in larger fish. Sound duration, pulse duration and the number of pulses increased whereas the peak frequency decreased with fish size, in both sound types (knocks and grunts). Interaction rate and the frequency of agonistic behaviour decreased with increasing fish size during competitive feeding sessions. The proportion of feeding interactions accompanied by sound production was similar in all size classes. However, the proportion of interactions accompanied by knocks (less aggressive sounds) and by grunts (more aggressive) increased and decreased with fish size, respectively. Taken together, these results suggest that smaller grey gurnards compete for food by contest tactics whereas larger specimens predominantly scramble for food, probably because body size gives an advantage in locating, capturing and handling prey. We further suggest that sounds emitted during feeding may potentially give information on the motivation and ability of the individual to compete for food resources. [source]


    Voice profile after type I or II laser chordectomies for T1a glottic carcinoma

    HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 11 2009
    Elisabeth V. Sjögren MD
    Abstract Background Can a "typical" voice in terms of auditory perception be defined after type I or II chordectomy? Do other parameters in a multidimensional voice protocol correlate to this perceptual profile? Methods Voice evaluation using a multidimensional voice protocol including perceptual (GRBAS; grade, roughness, breathiness, asthenia, strain scale), acoustic, aerodynamic, stroboscopic analyses, and self-assessment (Voice Handicap Index [VHI]) in a cohort of 37 consecutive patients with T1a midcord glottic carcinoma. Results Sixty-five percent of patients had dysphonia, dominated by mild breathiness (mean grade 1.4). Voice Handicap was minimal (mean VHI 19). Acoustic and aerodynamic parameters were only mildly deviant. The correlations between perceptual analysis and the other parameters were weak. Conclusion The typical laser treated voice (type I or II resections) is characterized by mild breathiness in perceptual analysis. Correlations with other parameters, including patients' self assessment, are weak. Therefore, these outcomes do not form 1 integrated voice profile. This may have consequences for clinical decision-making. © 2009 Wiley Periodicals, Inc. Head Neck, 2009 [source]


    Changes in infant directed speech in the first six months

    INFANT AND CHILD DEVELOPMENT, Issue 2 2006
    Kjellrun Englund
    Abstract The Mother,Infant Phonetic Interaction model (MIPhI) predicts that, compared with adult directed speech (ADS), in infant directed speech (IDS) vowels will be overspecified and consonants underspecified during the infants' first 6 months. In a longitudinal natural study, six mothers' ADS and IDS were recorded on 10 occasions during the first 6 months after their infants were born. Acoustic,phonetic measures, including the first two formant frequencies and duration for vowels and the duration of the fricative /s/, were used to test the MIPhI model with differences between IDS and ADS during the infants' first 6 months. Repeated measures analyses showed the fricative /s/ duration was stably longer in IDS, corresponding to an overspecification throughout the 6 months. The unexpected smaller vowel space for IDS than ADS was stably maintained over the six months, suggesting an underspecification of vowels. Vowel duration, which was generally longer in IDS than ADS, however, changed over time, decreasing in difference between IDS and ADS during month 3 and 4. Results invite adjustments to the MIPhI model, in particular related to infants' needs for perceptual enhancement of speech segments, and to the course of infant neurological and communicative development throughout the first 6 months. Copyright © 2006 John Wiley & Sons, Ltd. [source]


    Spectra of wavelet scale coefficients from process acoustic measurements as input for PLS modelling of pulp quality,

    JOURNAL OF CHEMOMETRICS, Issue 8-10 2002
    Anders Björk
    Abstract Acoustic and vibration signals are captured by simple standard accelerometers. These can often be mounted directly on operative process equipment, creating a completely non-invasive measurement system. The signals from the accelerometer are then amplified, digitized by an analogue-to-digital converter and stored in some suitable format in a PC. The method most often used for signal processing of acoustic data has been to apply variants of fast Fourier transform (FFT) on sampled data to produce a frequency domain representation. An alternative way tried here is to use the fast wavelet transform (FWT) in combination with FFT. The FWT has the advantage that it produces time-resolved representations and, on each time scale, different features can be extracted. However, in this case, time resolution has no meaning, since the starting points for data acquisitions were not fixed. The wavelet step can be seen as a series of pre-filters and it is here followed by FFT on coefficients at each wavelet scale. The results are compared to those obtained after FFT on the complete time series. We have used spectra of wavelet scale coefficients in an attempt to model pulp quality with PLS. In this case the number of points in the resulting wavelet multiresolution spectrum (WT-MRS) can be limited to a low number, e.g. 255 compared to 1025 with direct FFT on the time series. In the PLS modelling step the advantage is that the first two components describe Y much better than when using the conventional approach, e.g. 72% explained Y variance compared to 40%. A second advantage is that the model requires fewer coefficients. Copyright © 2002 John Wiley & Sons, Ltd. [source]


    Acoustic Startle Reactivity During Acute Alcohol Withdrawal in Rats That Differ in Genetic Predisposition Toward Alcohol Drinking: Effect of Stimulus Characteristics

    ALCOHOLISM, Issue 5 2004
    Julia A. Chester
    Abstract: Background: We have previously reported an association between greater alcohol withdrawal magnitude after a single alcohol exposure and a genetic predisposition toward low alcohol drinking in rats selectively bred for differences in alcohol intake when acoustic startle reactivity to a tone stimulus was used to index acute alcohol withdrawal. The purpose of this study was to examine whether the quality of the acoustic startle stimulus (noise versus tone) is important for detecting a genetic relationship between alcohol withdrawal magnitude and alcohol drinking behavior. Methods: Alcohol-naive male rats selectively bred for high alcohol intake [alcohol-preferring (P), high-alcohol-drinking (HAD)1, and HAD2] or low alcohol intake [alcohol-nonpreferring (NP), low-alcohol-drinking (LAD)1, and LAD2] received a single intragastric infusion of water or alcohol (4.0 g/20.3 ml/kg; 25% v/v), and acoustic startle test sessions were given at 14, 16, 18, 20, and 24 hr after infusion. Each test session consisted of a 5-min acclimation period followed by random presentation of various white noise stimuli (90, 100, 110, and 120 dB.) Results: Line differences in acoustic startle magnitude under control conditions were present in all three pairs of selectively bred lines; P rats showed a greater startle magnitude relative to NP rats, whereas both LAD lines showed a greater startle magnitude relative to both HAD lines. During alcohol withdrawal, the P, HAD1, and HAD2 lines showed enhanced startle magnitude compared with their water-treated controls. No change in startle magnitude during alcohol withdrawal was found in the NP, LAD1, or LAD2 lines. Conclusions: In contrast to our prior findings, these results showed a genetic association between high alcohol drinking and a greater startle response magnitude to a noise stimulus during alcohol withdrawal. It seems that the genetic association between alcohol drinking and alcohol withdrawal, as assessed by the acoustic startle response, depends on the quality of the acoustic startle stimulus. [source]


    Comments on "Gradient-Induced Acoustic and Magnetic Field Fluctuations in a 4T Whole-Body MR Imager" ,,

    MAGNETIC RESONANCE IN MEDICINE, Issue 2 2001
    Alan Barnett
    Abstract The results published in the article Gradient-Induced Acoustic and Magnetic Field Fluctuations in a 4T Whole-Body MR Imager by Wu et al. (Magn Reson Med 2000;44:532,536) appear to be consistent with the response of a time-stationary linear system. Since a linear system is more simply described than a nonlinear system, the authors are urged to reanalyze their data to test the linear-system hypothesis. Magn Reson Med 46:207, 2001. Published 2001 Wiley-Liss, Inc. [source]


    Microdissection or Microspot CO2 Laser for Limited Vocal Fold Benign Lesions: A Prospective Randomized Trial,

    THE LARYNGOSCOPE, Issue S92 2000
    Michael S. Benninger MD
    CO2 lasers have become an important technological advance and an integral tool for the laryngeal surgeon since the 1960s. Surgeons have used lasers for a variety of benign and malignant lesions in the larynx with good success. With better understanding of the microarchitecture of the vocal folds and the recognition of heat distribution into surrounding tissues that occurs with the use of standard CO2 lasers, questions and concerns have been raised regarding the use of the CO2 laser for benign lesions of the vocal folds. With the advent of the microspot CO2 laser with a spot size of less than 250 ,m, the potential heat distribution to the deeper layers of the lamina propria has been reduced. The microspot CO2 laser has been suggested to be an appropriate tool for the excision of superficial benign lesions of the vocal fold and may be considered as an appropriate treatment alternative to microdissection. Only a limited number of studies have compared the efficacy of microdissection versus microspot CO2 laser surgery in the larynx, and no prospective, randomized trials have been performed. Objective This study was designed to compare microspot CO2 laser excision and microdissection for superficial benign lesions confined to the free margin of the vocal fold. Study Design: A randomized, prospective trial comparing microspot CO2 laser excision and microdissection in the removal of nodules, polyps, and mucous retention cysts of the vocal fold. Methods Acoustic and aerodynamic measures and videostroboscopic and perceptual audio recordings evaluated by a panel of blinded viewers and listeners were studied preoperatively and 2 to 3 weeks and 5 to 12 weeks postoperatively. Surgical and recovery times were compared between the two groups. Results Thirty-seven patients met selection criteria and were enrolled, 21 in the microdissection group and 16 in the laser excision group. Significant improvements in videostroboscopic parameters were found over time in both groups. Significant improvements were noted for perceptual analysis over time for the laser excision group with nonsignificant improvements over time for the microdissection group. There was no difference in any measure between laser excision and microdissection at the two postoperative visits. There was no difference in surgical or recovery time between laser excision and microdissection. Acoustic and aerodynamic parameters were noncontributory in evaluating outcomes of treatment, since most values were normal before surgery. Conclusion No differences in clinical outcomes are identified when comparing microdissection with laser excision of nodules, polyps, and mucous retention cysts of the vocal folds. [source]


    Acoustic, semantic and phonetic influences in spoken warning signal words

    APPLIED COGNITIVE PSYCHOLOGY, Issue 8 2003
    Judy Edworthy
    Three experiments are reported which explore the relationship between semantic, acoustic and phonetic variables in the judgement of eight warning signal words. Experiment 1 shows that listeners can distinguish very clearly between urgent and non-urgent versions of the words when spoken by real speakers, and that some signal words such as ,deadly' and ,danger' score more highly than words such as ,attention' and ,don't'. It also shows that the three dimensions of perceived urgency, appropriateness and believability of these words are highly correlated. Experiment 2 replicates Experiment 1 using synthesized voices where acoustic variables are controlled. The semantic effects are replicated, and to some extent appropriateness and believability are found to function differently from that of perceived urgency. Experiment 3 compares the same set of eight signal words with a set of phonetically similar neutral words, showing that warning signal words are rated significantly higher, and largely maintain their previous rank ordering. Copyright © 2003 John Wiley & Sons, Ltd. [source]


    Development of multilayered cell-hydrogel composites using an acoustic focusing technique

    BIOTECHNOLOGY PROGRESS, Issue 2 2010
    Jason P. Mazzoccoli
    Abstract Multilayered composites, composed of mammalian cells arranged in a hydrogel, have been prepared using an acoustic focusing technique. Acoustic focusing is a simple, nonchemical technique that allows for the fast arrangement of cells in matrices where the control of cell geometry is beneficial. Breast cancer cells (MDA-MB231) were dispersed in a 30 wt % solution of poly(ethylene glycol) diacrylate (PEGDA) of molecular weight 400 at a density of 5 × 106 cells/mL of PEGDA solution. An ultrasonic field was used to organize the cells before polymerization of PEGDA. Disk-shaped hydrogel composites, typically 1 cm in diameter and 2-mm thick were prepared based on a PEGDA solution volume of 130 ,L. At an acoustic frequency of 2.32 MHz, composites having cells positioned within concentric cylindrical shells interspersed with zones of cell-free hydrogel were produced. The cells were located in annuli approximately 80-,m thick and about 300 ,m apart. The structure and viability of the cells within these constructs were studied using a fluorescent LIVE/DEAD assay. The viability of the cells was on the order of 50%. For the conditions used in this study, cell death was primarily attributed to exposure of cells to the PEGDA solution prior to polymerization, rather than adverse effects of polymerization or the sound field itself. © 2009 American Institute of Chemical Engineers Biotechnol. Prog., 2010 [source]


    Acoustic and Morphological Differentiation in the Frog Allobates femoralis: Relationships with the Upper Madeira River and Other Potential Geological Barriers

    BIOTROPICA, Issue 5 2008
    Pedro Ivo Simões
    ABSTRACT We studied patterns of call acoustics and external morphological differentiation in populations of the dart-poison frog Allobates femoralis occurring in forested areas along a 250-km stretch of the upper Madeira River, Brazil. Multivariate analyses of variance using principal components representing shared acoustic and morphological parameters distinguished three groups in relation to call structure and external morphology: (1) populations belonging to a two-note call morphotype; (2) populations with four-note calls inhabiting the left riverbank; and (3) populations with four-note calls inhabiting the right riverbank. Our results report a case of Amazonian anuran diversity hidden by current taxonomy and provide evidence for the upper Madeira River being a boundary between distinct populations of A. femoralis, and suggest a new taxonomic interpretation for these groups. Samples that did not fit into the general differentiation pattern and the existence of a well-defined contact zone between two morphotypes on the left riverbank indicate that mechanisms complementary to river-barrier hypotheses are necessary to explain the phenotypic differentiation between populations. Our study shows that at least one anuran species shows congruence between population differentiation and separation by a large Amazonian river, as documented for birds and mammals. Conservation efforts should not consider the taxon now known as A. femoralis as a homogeneous entity. There is much within-taxon variability, which can be probably explained partly by the existence of cryptic species, partly by geological barriers and part of which currently has no obvious explanation. RESUMO Estudamos padrões de diferenciação em acústica de cantos e morfologia externa em populações da rã-venenosa Allobates femoralis em áreas de floresta ao longo do alto Rio Madeira, Estado de Rondônia, Brasil, utilizando dados de 19 pontos de coleta estabelecidos em um trecho de 250 km do rio. Dois morfotipos distintos foram encontrados na área de estudo. Um, com cantos de anúncio constituídos por 2 notas, ocorre apenas na porção superior da margem esquerda do Rio Madeira, alcançando uma zona de contato com o segundo morfotipo à jusante, onde não há qualquer barreira de dispersão aparente na atualidade. O segundo morfotipo, com cantos constituídos por 4 notas, ocorre em ambos os lados do rio. Análises de variância multivariadas usando componentes principais representando parâmetros acústicos e morfológicos apontaram três grupos distintos em relação à estrutura dos cantos e morfologia externa: (1) populações pertencentes ao morfotipo com cantos de 2 notas; (2) populações pertencentes ao morfotipo com cantos de 4 notas da margem esquerda; e (3) populações pertencentes ao morfotipo de 4 notas da margem direita. Nossos resultados apontam um caso de diversidade de anuros amazônicos mascarada pela taxonomia atual e fornece evidências sobre o papel do Rio Madeira como um limite entre populações diferenciadas da espécie, sugerindo uma Re-interpretação taxonômica destes grupos. Amostras que não se encaixam no padrão geral de diferenciação e a existência de uma zona de contato bem definida entre dois morfotipos na margem esquerda indicam que mecanismos complementares à hipóteses de rios como barreiras são necessários para explicar a diferenciação fenotípica de Allobates femoralis. Nosso estudo mostra que ao menos uma espécie de anuro apresenta congruência entre diferenciação populacional e sua separação por um grande rio amazônico, como já documentado para aves e mamíferos. Esforços de conservação não deveriam considerar o táxon Allobates femoralis como uma entidade homogênea. Há uma grande variabilidade dentro deste táxon, o que pode ser provavelmente explicado em parte pela existência de espécies crípticas, em parte por barreiras geológicas e em parte por mecanismos ainda desconhecidos. [source]


    DS/CDMA throughput of a multi-hop sensor network in a Rayleigh fading underwater acoustic channel

    CONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 8 2007
    Choong Hock Mar
    Abstract Asynchronous half-duplex Direct-Sequence Code-Division Multiple-Access (DS/CDMA) is a suitable candidate for the MAC protocol design of underwater acoustic (UWA) sensor networks owing to its many attractive features. Our ad-hoc multi-hop network is infrastructureless in that it is without centralized base stations or power control. Hence, we develop an asynchronous distributed half-duplex control protocol to regulate between the transmitting and receiving phases of transmissions. Furthermore, multi-hop communications are very sensitive to the time variability of the received signal strength in the fading channel and the ambient noise dominated by snapping shrimp in harsh underwater environments, because a broken link in the multi-hop path is enough to disrupt communications and initiate new route searches. In our configuration, we use the Ad hoc On-demand Distance Vector (AODV) routing protocol optimized for UWA networks. Empirical studies show that we can model the channel as a slow-varying frequency non-selective Rayleigh fading channel. We theoretically analyze the throughput of our configuration by considering three salient features: the ability of the receiver to demodulate the data, the effect of our control protocol and the effect of disconnections on the generation of routing packets. The throughput under various operating conditions is then examined. It is observed that at optimal node separation, the throughput is improved by a factor of 10. Copyright © 2007 John Wiley & Sons, Ltd. [source]


    Effects of buspirone and alprazolam treatment on the startle-potentiated startle response

    DEPRESSION AND ANXIETY, Issue 3 2004
    Randall L. Commissaris Ph.D.
    Abstract The startle potentiated startle (SPS) paradigm has been reported to be an effective procedure for studying the conditioned enhancement of acoustic startle in the absence of electric shocks or extinction. This study examines the effects of two anxiolytic treatments, buspirone and alprazolam, on this SPS effect. Subjects were tested in the SPS paradigm 2 days a week (Monday and Thursday) for 10 weeks. Each startle test session consisted of 10 Noise Alone trials (115 dB acoustic noise burst presented for 40 ms) and 10 Light+Noise trials (115 dB acoustic stimuli presented during the latter 40 ms of a 3,540 ms period in which a 15-watt light was illuminated). Although there was no difference in startle amplitude on Noise Alone trials when compared to Light+Noise trials initially, by the end of the first test session and continuing throughout the duration of the experiment, startle amplitude on Light+Noise trials was significantly (approximately 50,75%) greater than on Noise Alone trials. After five control (i.e., no injection) SPS test sessions, once-weekly drug challenges were conducted over the course of 7 weeks. In these weekly drug challenges, subjects received acute treatment with various doses of the benzodiazepine anxiolytic alprazolam (0.25, 0.5, 1.0 mg/kg) or the novel anxiolytic buspirone (1.0, 2.0, 4.0 mg/kg); subjects also received vehicle treatment (0.5% methylcellulose) on one treatment day. All treatments were administered intraperitoneally (IP), 15 min before the start of startle testing. Consistent with previous reports, buspirone increased and alprazolam decreased startle amplitude on the Noise Alone trials; these effects were dose-related. Both agents reduced the magnitude of the SPS effect when it was expressed as the Light+Noise startle amplitude minus the Noise Alone startle amplitude. These findings are similar to the effects of these treatments in the traditional shock-based fear-potentiated startle paradigm. Depression and Anxiety 19:146,151, 2004. © 2004 Wiley-Liss, Inc. [source]


    Maladaptation to mental stress mitigated by the adaptive immune system via depletion of naturally occurring regulatory CD4+CD25+ cells

    DEVELOPMENTAL NEUROBIOLOGY, Issue 6 2006
    Hagit Cohen
    Abstract Peripheral cellular immunity was recently shown to play a critical role in brain plasticity and performance. The antigenic specificity of the participating T cells, however, was not investigated, and nor was their relevance to psychological stress. Here we show, using a mouse model, that adaptive immunity mitigates maladaptation to the acute psychological stress known to trigger abnormal behaviors reminiscent of human post-traumatic stress disorder. Assessment of behavioral adaptation (measured by the acoustic startle response and avoidance behavior) in mice after their exposure to predator odor revealed that maladaptation was several times more prevalent in T cell-deficient mice than in their wild-type counterparts. A single population of T cells reactive to central nervous system (CNS)-associated self-protein was sufficient to endow immune-deficient mice with the ability to withstand the psychological stress. Naturally occurring CD4+CD25+ regulatory T cells were found to suppress this endogenous anti-stress attribute. These findings suggest that T cells specific to abundantly expressed CNS antigens are responsible for brain tissue homeostasis and help the individual to cope with stressful life episodes. They might also point the way to development of immune-based therapies for mental disorders, based either on up-regulation of T cells that partially cross-react with self-antigens or on weakening of the activity of regulatory T cells. © 2006 Wiley Periodicals, Inc. J Neurobiol, 2006 [source]


    Effects of excessive glucocorticoid receptor stimulation during early gestation on psychomotor and social behavior in the rat ,

    DEVELOPMENTAL PSYCHOBIOLOGY, Issue 2 2010
    Karine Kleinhaus
    Abstract Severe psychological stress in the first trimester of pregnancy increases the risk of schizophrenia in the offspring. To begin to investigate the role of glucocorticoid receptors in this association, we determined the effects of the glucocorticoid dexamethasone (2,mg/kg), administered to pregnant rats on gestation days 6,8, on maternal behaviors and schizophrenia-relevant behaviors in the offspring. Dams receiving dexamethasone exhibited increased milk ejection bouts during nursing. Offspring of dexamethasone-treated dams (DEX) showed decreased juvenile social play and a blunted acoustic startle reflex in adolescence and adulthood, effects that were predicted by frequency of milk ejections in the dams. DEX offspring also showed increased prepulse inhibition of startle and reduced amphetamine-induced motor activity, effects not correlated with maternal behavior. It is postulated that over-stimulation of receptors targeted by glucocorticoids in the placenta or other maternal tissues during early gestation can lead to psychomotor and social behavioral deficits in the offspring. Moreover, some of these deficits may be mediated by alterations in postnatal maternal behavior and physiology produced by early gestational exposure to excess glucocorticoids. © 2010 Wiley Periodicals, Inc. Dev Psychobiol 52:121,132, 2010 [source]


    Social Behavior of Larvae of the Neotropical Processionary Weevil Phelypera distigma (Boheman) (Coleoptera: Curculionidae: Hyperinae)

    ETHOLOGY, Issue 7 2004
    James T. Costa
    Socially gregarious behavior among free-living leaf-eating insect larvae occurs mostly among Lepidoptera, Symphyta, and a few Chyrsomelidae (Coleoptera). However, the Neotropical hyperine curculionid Phelypera distigma has also evolved this lifestyle, exhibiting a suite of social behaviors unique among beetles. The larvae are nomadic processionary foragers that punctuate foraging bouts with rosette-shaped resting formations (cycloalexy). Larvae also vibrate or bob their heads rapidly when moving, especially when in contact with conspecifics, and this suggests acoustic or vibrational communication. In this study we used observational and experimental approaches to investigate the basis of processionary, cycloalexic,and head-vibration behavior of this species. Larvae used both trail pheromones and thigmotactic signals to organize themselves into head-to-tail processionary columns. The trail pheromone, produced from the center of the abdomen, remains active for up to 4 h. Processions are not consistently led by particular individuals, but dynamically change over time and often temporarily break into two or more subprocessions. Subprocessions reunite through use of the trail pheromone. We found no evidence that head-bobbing generates attraction through substrate-borne or acoustic signals, but this behavior functions in direct contact to excite group activity. Time-lapse videography used to analyze cycloalexic group formation showed that larvae transition from feeding in a line along the leaf margin to cycloalexic formations on the upper leaf surface via a coordinated back-up movement that brings the posterior tip of their abdomens into contact. We identify three phases of cycloalexic formation: line-up, back-up, and an adjustment phase. Complete assembly can be achieved in as little as 5 s, but often the two phases establishing the basic rosette lasts 5,10 min, while the adjustment phase slowly tightens the group over a period of up to an hour. Collectively these studies present the first documented case of chemical trail marking in a beetle, and provide insight into a remarkable social-behavioral repertoire convergent in key respects with the better-studied social caterpillars and sawflies. [source]


    Early onset of deafening-induced song deterioration and differential requirements of the pallial-basal ganglia vocal pathway

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 12 2008
    Haruhito Horita
    Abstract Similar to humans, songbirds rely on auditory feedback to maintain the acoustic and sequence structure of adult learned vocalizations. When songbirds are deafened, the learned features of song, such as syllable structure and sequencing, eventually deteriorate. However, the time-course and initial phases of song deterioration have not been well studied, particularly in the most commonly studied songbird, the zebra finch. Here, we observed previously uncharacterized subtle but significant changes to learned song within a few days following deafening. Syllable structure became detectably noisier and silent intervals between song motifs increased. Although song motif sequences remained stable at 2 weeks, as previously reported, pronounced changes occurred in longer stretches of song bout sequences. These included deletions of syllables between song motifs, changes in the frequency at which specific chunks of song were produced and stuttering for birds that had some repetitions of syllables before deafening. Changes in syllable structure and song bout sequence occurred at different rates, indicating different mechanisms for their deterioration. The changes in syllable structure required an intact lateral part but not the medial part of the pallial-basal ganglia vocal pathway, whereas changes in the song bout sequence did not require lateral or medial portions of the pathway. These findings indicate that deafening-induced song changes in zebra finches can be detected rapidly after deafening, that acoustic and sequence changes can occur independently, and that, within this time period, the pallial-basal ganglia vocal pathway controls the acoustic structure changes but not the song bout sequence changes. [source]


    Primary and secondary neural networks of auditory prepulse inhibition: a functional magnetic resonance imaging study of sensorimotor gating of the human acoustic startle response

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 8 2007
    Linda E. Campbell
    Abstract Feedforward inhibition deficits have been consistently demonstrated in a range of neuropsychiatric conditions using prepulse inhibition (PPI) of the acoustic startle eye-blink reflex when assessing sensorimotor gating. While PPI can be recorded in acutely decerebrated rats, behavioural, pharmacological and psychophysiological studies suggest the involvement of a complex neural network extending from brainstem nuclei to higher order cortical areas. The current functional magnetic resonance imaging study investigated the neural network underlying PPI and its association with electromyographically (EMG) recorded PPI of the acoustic startle eye-blink reflex in 16 healthy volunteers. A sparse imaging design was employed to model signal changes in blood oxygenation level-dependent (BOLD) responses to acoustic startle probes that were preceded by a prepulse at 120 ms or 480 ms stimulus onset asynchrony or without prepulse. Sensorimotor gating was EMG confirmed for the 120-ms prepulse condition, while startle responses in the 480-ms prepulse condition did not differ from startle alone. Multiple regression analysis of BOLD contrasts identified activation in pons, thalamus, caudate nuclei, left angular gyrus and bilaterally in anterior cingulate, associated with EMG-recorded sensorimotor gating. Planned contrasts confirmed increased pons activation for startle alone vs 120-ms prepulse condition, while increased anterior superior frontal gyrus activation was confirmed for the reverse contrast. Our findings are consistent with a primary pontine circuitry of sensorimotor gating that interconnects with inferior parietal, superior temporal, frontal and prefrontal cortices via thalamus and striatum. PPI processes in the prefrontal, frontal and superior temporal cortex were functionally distinct from sensorimotor gating. [source]


    Cellular mechanisms of the trigeminally evoked startle response

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 7 2003
    Susanne Schmid
    Abstract The startle response is an important mammalian model for studying the cellular mechanisms of emotions and of learning. It consists of contractions of facial and skeletal muscles in response to sudden acoustic, tactile or vestibular stimuli. Whereas the acoustic startle pathway is well described, only a few recent studies have investigated the tactile startle pathway. It was proposed that there is a direct projection from the principal sensory nucleus to the central sensorimotor interface of the startle response, which is formed by the giant neurons in the caudal pontine reticular formation. We explored this projection in greater detail in vitro. Anterograde tracing in rat brain slices confirmed projections with large axon terminals from the ventral part of the principal sensory nucleus to the lateral caudal pontine reticular formation. Electrophysiological studies revealed a monosynaptic glutamatergic connection between principal sensory nucleus neurons and caudal pontine reticular formation giant neurons. The synapses displayed paired-pulse facilitation at high-frequency stimulation, and homosynaptic depression at 1 Hz stimulation. The latter form of plasticity is thought to underlie habituation of the startle response. Furthermore, postsynaptic currents in caudal pontine reticular formation giant neurons evoked by principal sensory nucleus neuron stimulation summed in a linear way with signals evoked by stimulation of auditory afferents. Synaptic plasticity and summation of synaptic currents correspond well with in vivo data previously published by other groups. We thus presume that these synapses mediate trigeminal input to the startle pathway. [source]


    Sex differences in anxiety, sensorimotor gating and expression of the ,4 subunit of the GABAA receptor in the amygdala after progesterone withdrawal

    EUROPEAN JOURNAL OF NEUROSCIENCE, Issue 3 2003
    M. Gulinello
    Abstract In a progesterone withdrawal (PWD) model of premenstrual anxiety, we have previously demonstrated that increased hippocampal expression of the ,4 subunit of the GABAA receptor (GABAA -R) is closely associated with higher anxiety levels in the elevated plus maze. However, several studies indicate that sex differences in regulation of the GABAA -R in specific brain regions may be an important factor in the observed gender differences in mood disorders. Thus, we investigated possible sex differences in GABAA -R subunit expression and anxiety during PWD. To this end, we utilized the acoustic startle response (ASR) to assess anxiety levels in male and female rats undergoing PWD as the ASR is also applicable to the assessment of human anxiety responses. We also investigated GABAA -R ,4 subunit expression in the amygdala, as the amygdala directly regulates the primary startle circuit. Female rats exhibited a greater ASR during PWD than controls, indicating higher levels of anxiety and arousal. In contrast, male rats undergoing PWD did not demonstrate an increased ASR. The sex differences in the ASR were paralleled by sex differences in the expression of the GABAA -R ,4 subunit in the amygdala such that ,4 subunit expression was up-regulated in females during PWD whereas ,4 levels in males undergoing PWD were not altered relative to controls. These findings might have implications regarding gender differences in human mood disorders and the aetiology of premenstrual anxiety. [source]


    Czochralski-grown Single Crystals with Acentric Symmetry Group 32,

    ADVANCED ENGINEERING MATERIALS, Issue 7 2004
    R.B. Heimann
    Single crystals with calcium gallium germanate (Ca3Ga2Ge4O14, CGG) structure such as langasite La3Ga5SiO14 (LGS), its niobium (,langanite', La3Ga5.5Nb0.5O14, LGN) and tantalum (,langataite', La3Ga5.5Ta0.5O14, LGT) analogs as well as strontium niobium gallium silicate (Sr3NbGa3Si2O14, SNGS) and strontium tantalum gallium silicate (Sr3TaGa3Si2O14, STGS) were grown with high perfection by the Czochralski pulling technique. Specific electric conductivity, optical activity, and dielectric, piezoelectric, bulk and surface acoustic, elastic, and electro-optic properties were measured. [source]


    Evaluating the physiological and physical consequences of capture on post-release survivorship in large pelagic fishes

    FISHERIES MANAGEMENT & ECOLOGY, Issue 2 2007
    G. B. SKOMAL
    Abstract, Sharks, tunas and billfishes are fished extensively throughout the world. Domestic and international management measures (quotas, minimum sizes, bag limits) mandate release of a large, yet poorly quantified, number of these fishes annually. Post-release survivorship is difficult to evaluate, because standard methods are not applicable to large oceanic fishes. This paper presents information on the current approaches to characterising capture stress and survivorship in sharks, tunas and marlins. To assess mortality associated with capture stress, researchers must examine the cumulative impacts of physical trauma and physiological stress. Physical trauma, manifested as external and internal tissue and organ damage, is caused by fishing gear and handling. Gross examination and histopathological sampling have been used to assess physical trauma and to infer post-release survivorship. Exhaustive anaerobic muscular activity and time out of water cause physiological stress, which has been quantified in these fishes through the analyses of blood chemistry. Conventional, acoustic and archival tagging have been used to assess post-release survivorship in these species. Future studies relating capture stress and post-release survivorship could yield information that helps fishermen increase survivorship when practicing catch and release. [source]


    Interannual spatial variability of krill (Euphausia superba) influences seabird foraging behavior near Elephant Island, Antarctica

    FISHERIES OCEANOGRAPHY, Issue 1 2009
    JARROD A. SANTORA
    Abstract We investigate the influence of krill (principally Euphausia superba) patchiness on the foraging distributions of seabirds to understand how variation in krill influences patch dynamics between krill and birds. At sea-surveys were conducted near Elephant Island, Antarctica, for 3 yr (2004,2006) during the annual U.S. Antarctic Marine Living Resources (AMLR) program. Standardized strip-transect surveys were used to map seabirds, and a combination of acoustic and net surveys was used to map krill. We measured patch size of krill and seabirds and elucidated how krill patch dynamics influence foraging seabirds. The spatial association between krill and predators was influenced by the size and arrangement of krill patches. We found a negative relationship between abundance and patchiness of krill and predators, indicating that when krill is less abundant, its predators are less abundant and concentrated. We conclude that annual patch dynamics of krill strongly influences the local abundance and distribution of seabirds. Such information should be used to interpret potential interactions between seabirds and krill fisheries operating near Elephant Island. [source]


    Flow-field observations of a tidally driven island wake used by marine mammals in the Bay of Fundy, Canada

    FISHERIES OCEANOGRAPHY, Issue 5 2007
    D. W. JOHNSTON
    Abstract Correlations between fine-scale oceanographic features and aggregations of marine mammals are frequently reported, but the physical forces shaping these relationships are rarely explored. We conducted a series of oceanographic observations and remote sensing surveys of an oceanographic feature near Grand Manan Island known to attract marine mammals on flood tides. We tracked drift drogues from cliff-top with a theodolite and conducted box-type surveys with an acoustic Doppler current profiler (ADCP) to assess flow patterns within the oceanographic feature. The feature was also visualized with Synthetic Aperture Radar (SAR) scenes. Drift drogues were advected towards a shear line originating near the northern tip of the island and entrained in one or more eddies downstream. ADCP surveys confirmed the presence of the shear line between rapid easterly flow and slower return flow. As the tide progressed, the shear line extended and manifested a single anti-cyclonic eddy at its distal end. As the flood tide progressed, northerly flow along the eastern shore of the island intensified and deflected the shear line northwards, shedding the eddy at slack high water. SAR images confirmed the presence of the shearline and eddy system, illustrating the evolution of a wake behind the island on flood tides. Profiles of flow direction and acoustic backscatter revealed secondary flows within the wake consistent with models and observations of other wakes. Oceanographic and remote sensing observations confirm that an island wake is generated by tidal flow past Grand Manan Island and provide an ecological context for the predictable aggregations of odontocete and mysticete cetaceans observed foraging within this region. [source]


    Hyperactivity, startle reactivity and cell-proliferation deficits are resistant to chronic lithium treatment in adult Nr2e1frc/frc mice

    GENES, BRAIN AND BEHAVIOR, Issue 7 2010
    B. K. Y. Wong
    The NR2E1 region on Chromosome 6q21-22 has been repeatedly linked to bipolar disorder (BP) and NR2E1 has been associated with BP, and more specifically bipolar I disorder (BPI). In addition, patient sequencing has shown an enrichment of rare candidate-regulatory variants. Interestingly, mice carrying either spontaneous (Nr2e1frc) or targeted (Tlx,) deletions of Nr2e1 (here collectively known as Nr2e1 -null) show similar neurological and behavioral anomalies, including hypoplasia of the cerebrum, reduced neural stem cell proliferation, extreme aggression and deficits in fear conditioning; these are the traits that have been observed in some patients with BP. Thus, NR2E1 is a positional and functional candidate for a role in BP. However, no Nr2e1 -null mice have been fully evaluated for behaviors used to model BP in rodents or pharmacological responses to drugs effective in treating BP symptoms. In this study we examine Nr2e1frc/frc mice, homozygous for the spontaneous deletion, for abnormalities in activity, learning and information processing, and cell proliferation; these are the phenotypes that are either affected in patients with BP or commonly assessed in rodent models of BP. The effect of lithium, a drug used to treat BP, was also evaluated for its ability to attenuate Nr2e1frc/frc behavioral and neural stem cell-proliferation phenotypes. We show for the first time that Nr2e1 -null mice exhibit extreme hyperactivity in the open field as early as postnatal day 18 and in the home cage, deficits in open-field habituation and passive avoidance, and surprisingly, an absence of acoustic startle. We observed a reduction in neural stem/progenitor cell proliferation in Nr2e1frc/frc mice, similar to that seen in other Nr2e1 -null strains. These behavioral and cell-proliferation phenotypes were resistant to chronic-adult-lithium treatment. Thus, Nr2e1frc/frc mice exhibit behavioral traits used to model BP in rodents, but our results do not support Nr2e1frc/frc mice as pharmacological models for BP. [source]


    Abnormal social behaviors in mice lacking Fgf17

    GENES, BRAIN AND BEHAVIOR, Issue 3 2008
    K. Scearce-Levie
    The fibroblast growth factor family of secreted signaling molecules is essential for patterning in the central nervous system. Fibroblast growth factor 17 (Fgf17) has been shown to contribute to regionalization of the rodent frontal cortex. To determine how Fgf17 signaling modulates behavior, both during development and in adulthood, we studied mice lacking one or two copies of the Fgf17 gene. Fgf17-deficient mice showed no abnormalities in overall physical growth, activity level, exploration, anxiety-like behaviors, motor co-ordination, motor learning, acoustic startle, prepulse inhibition, feeding, fear conditioning, aggression and olfactory exploration. However, they displayed striking deficits in several behaviors involving specific social interactions. Fgf17-deficient pups vocalized less than wild-type controls when separated from their mother and siblings. Elimination of Fgf17 also decreased the interaction of adult males with a novel ovariectomized female in a social recognition test and reduced the amount of time opposite-sex pairs spent engaged in prolonged, affiliative interactions during exploration of a novel environment. After social exploration of a novel environment, Fgf17-deficient mice showed less activation of the immediate-early gene Fos in the frontal cortex than wild-type controls. Our findings show that Fgf17 is required for several complex social behaviors and suggest that disturbances in Fgf17 signaling may contribute to neuropsychiatric diseases that affect such behaviors. [source]


    Spectral-element simulations of wave propagation in porous media

    GEOPHYSICAL JOURNAL INTERNATIONAL, Issue 1 2008
    Christina Morency
    SUMMARY We present a derivation of the equations describing wave propagation in porous media based upon an averaging technique which accommodates the transition from the microscopic to the macroscopic scale. We demonstrate that the governing macroscopic equations determined by Biot remain valid for media with gradients in porosity. In such media, the well-known expression for the change in porosity, or the change in the fluid content of the pores, acquires two extra terms involving the porosity gradient. One fundamental result of Biot's theory is the prediction of a second compressional wave, often referred to as ,type II' or ,Biot's slow compressional wave', in addition to the classical fast compressional and shear waves. We present a numerical implementation of the Biot equations for 2-D problems based upon the spectral-element method (SEM) that clearly illustrates the existence of these three types of waves as well as their interactions at discontinuities. As in the elastic and acoustic cases, poroelastic wave propagation based upon the SEM involves a diagonal mass matrix, which leads to explicit time integration schemes that are well suited to simulations on parallel computers. Effects associated with physical dispersion and attenuation and frequency-dependent viscous resistance are accommodated based upon a memory variable approach. We perform various benchmarks involving poroelastic wave propagation and acoustic,poroelastic and poroelastic,poroelastic discontinuities, and we discuss the boundary conditions used to deal with these discontinuities based upon domain decomposition. We show potential applications of the method related to wave propagation in compacted sediments, as one encounters in the petroleum industry, and to detect the seismic signature of buried landmines and unexploded ordnance. [source]


    GLT-1 upregulation impairs prepulse inhibition of the startle reflex in adult rats

    GLIA, Issue 7 2009
    Michele Bellesi
    Abstract We tested the hypothesis that glutamate transporter GLT-1 (also known as EAAT2) plays a role in the regulation of prepulse inhibition (PPI) of the acoustic startle reflex, a simple form of information processing which is reduced in schizophrenia. To do this, we studied PPI in rats treated with ceftriaxone (200 mg/kg/day for 8 days), an antibiotic that selectively enhances GLT-1 expression and activity. We showed that ceftriaxone-induced GLT-1 upregulation is associated with impaired PPI of the startle, that this effect is reversed by dihydrokainate, a GLT-1 antagonist, that GLT-1 expression correlates negatively with PPI, and that PPI normalizes when GLT-1a levels return to baseline. Our data indicate that GLT-1 regulates PPI of the startle reflex. © 2008 Wiley-Liss, Inc. [source]


    Voice profile after type I or II laser chordectomies for T1a glottic carcinoma

    HEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 11 2009
    Elisabeth V. Sjögren MD
    Abstract Background Can a "typical" voice in terms of auditory perception be defined after type I or II chordectomy? Do other parameters in a multidimensional voice protocol correlate to this perceptual profile? Methods Voice evaluation using a multidimensional voice protocol including perceptual (GRBAS; grade, roughness, breathiness, asthenia, strain scale), acoustic, aerodynamic, stroboscopic analyses, and self-assessment (Voice Handicap Index [VHI]) in a cohort of 37 consecutive patients with T1a midcord glottic carcinoma. Results Sixty-five percent of patients had dysphonia, dominated by mild breathiness (mean grade 1.4). Voice Handicap was minimal (mean VHI 19). Acoustic and aerodynamic parameters were only mildly deviant. The correlations between perceptual analysis and the other parameters were weak. Conclusion The typical laser treated voice (type I or II resections) is characterized by mild breathiness in perceptual analysis. Correlations with other parameters, including patients' self assessment, are weak. Therefore, these outcomes do not form 1 integrated voice profile. This may have consequences for clinical decision-making. © 2009 Wiley Periodicals, Inc. Head Neck, 2009 [source]


    A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats

    HIPPOCAMPUS, Issue 2 2008
    Denise Manahan-Vaughan
    Abstract Schizophrenia is mostly a progressive psychiatric illness. Although cognitive changes in chronic schizophrenia have been investigated, little is known about the consequences of a single psychotic episode on memory mechanisms and formation. We investigated changes in hippocampal long-term potentiation (LTP) and spatial memory in a rat model of an acute psychotic episode. Application of NMDA receptor antagonists, such as MK801 (dizolcilpine) in rats, have been shown to give rise to an acute and short-lasting behavioral state, which mirrors many symptoms of schizophrenia. Furthermore, NMDA antagonist-intake in humans elicits symptoms of schizophrenia such as hallucinations, delusions, and affective blunting. We therefore treated animals with a single systemic injection of MK801 (5 mg/kg). Increased stereotypy, locomotion, and ataxia were evident immediately after MK801-treatment, with effects disappearing within 24 h. MK801-treatment caused a disruption of prepulse inhibition of the acoustic startle reflex, 1 day but not 7 or 28 days after treatment. These effects were consistent with the occurrence of an acute psychotic episode. LTP was profoundly impaired in freely moving rats 7 days after MK801 application. Four weeks after treatment, a slight recovery of LTP was seen, however marked deficits in long-term spatial memory were evident. These data suggest that treatment with MK801 to generate an acute psychotic episode in rats, gives rise to grave disturbances in synaptic plasticity and is associated with lasting impairments with the ability to form spatial memory. © 2007 Wiley-Liss, Inc. [source]