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Absolute Terms (absolute + term)
Selected AbstractsRelative and Absolute Benefits: Main Results Should be Reported in Absolute TermsPACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 8 2007JOHN D. FISHER M.D. No abstract is available for this article. [source] (Re)designing mediation to address the nuances of power imbalanceCONFLICT RESOLUTION QUARTERLY, Issue 2 2001Ilan G. Gewurz This paper addresses the complex relationship between negotiating power and mediation. It begins with the premise that to say in absolute terms that mediation is or is not an effective way of dealing with power imbalance is to ignore the complexity of both the concept of power and the range of processes that can be deemed mediation. This article examines sources of power in an effort to develop a clear, yet thorough, understanding of negotiating power. It then turns to the scholarship on mediation, highlighting key characteristics that distinguish mediation approaches from one another and advancing the debate on what constitutes mediation. Finally, the article highlights bow a specific style of mediation may be appropriate for a given situation, depending on the existing power dynamics between the disputing parties. [source] The Economics of HIV/AIDS: A SurveyDEVELOPMENT POLICY REVIEW, Issue 1 2003Edoardo Gaffeo This article surveys the main economic issues associated with the HIV/AIDS epidemic, paying special attention to sub,Saharan Africa. It explores the economic and behavioural determinants of HIV transmission, the microeconomics of market failures associated with high HIV prevalence, the prospects for regional development from a macroeconomic perspective and the efficient design of policies for coping with the epidemic. In line with the recent appeal by the UN Secretary General, the article argues that, without a decisive effort to halt HIV/AIDS, people living in the region are bound to experience a further fall in their standard of living in both relative and absolute terms. However, to be effective, anti,AIDS programmes must be rooted in sound economic principles. [source] Measurement of Left Ventricular Ejection Fraction by Real Time 3D Echocardiography in Patients with Severe Systolic Dysfunction: Comparison with Radionuclide AngiographyECHOCARDIOGRAPHY, Issue 1 2010Hajo Müller M.D. Aim: Measurement of left ventricular ejection fraction (LVEF) using real time 3D echocardiography (3DE) has been performed in subjects with preserved or modestly reduced systolic function. Our aim was to evaluate this technique in the subset of patients with severe systolic dysfunction. Methods and results: Consecutive patients with LVEF less than 0.35 at two-dimensional echocardiography were included. LVEF obtained by 3DE was compared to the value measured by radionuclide angiography (RNA). Real time full-volume 3DE was performed, with offline semiautomated measurement of LVEF using dedicated software (Cardioview RT, Tomtec) by a single observer blinded to the results of RNA. A total of 50 patients were evaluated, of whom 38 (76%, 27 males, age 69 ± 13 years) had a 3DE of sufficient quality for analysis. LVEF for this group was 0.21 ± 0.07 using 3DE and 0.27 ± 0.08 using RNA. The agreement between the two techniques was rather poor (r = 0.49; P < 0.001; 95% limits of agreements of ,0.20 to 0.09). Truncation of the apex was observed in 6 of 38 (16%) patients. Conclusion: In patients with severe systolic dysfunction, 3DE shows poor agreement for measurement of LVEF as compared to RNA. There may be underestimation of up to 20% in absolute terms by 3DE. Accordingly, the two methods are not interchangeable for the follow-up of LV function. A limitation of 3DE may, at least in part, be related to the incomplete incorporation of the apical region into the pyramidal image sector in patients with dilated hearts. (Echocardiography 2010;27:58-63) [source] Axial Rotation of the Lower Human Spine by Rhythmic Torques Automatically Generated at the Resonant FrequencyEXPERIMENTAL PHYSIOLOGY, Issue 3 2003E. Geoffrey Walsh Subjects sat on a ,Balans' chair supported by the shaft of a large torque generator. The lower but not the upper part of the body was free to make to/fro movements maintained by feeding back a modified velocity signal to the generator. The stiffness could be increased by the use of a position signal. Using the equations for a torsion pendulum the good linearity observed in relationship to the applied forces allowed stiffness, inertia, damping, critical damping and the damping factor to be determined in absolute terms. The method enables parameters relevant to back function and problems to be evaluated. Eleven adults acted as subjects. [source] Relationships between head size, bite force, prey handling efficiency and diet in two sympatric lacertid lizardsFUNCTIONAL ECOLOGY, Issue 6 2002D. Verwaijen Summary 1Relationships between morphology, bite force capacity, prey handling efficiency and trophic niche were explored in two sympatric species of lacertid lizards, Podarcis melisellensis (Braun 1877) and Lacerta oxycephala Duméril & Bibron 1839. 2Head shape showed little variation, but head size (absolute and relative to snout,vent length, SVL) differed between species and sexes. Males have larger heads than females, both absolute and relative to their SVL. In absolute terms, male P. melisellensis have larger heads than male L. oxycephala, but the reverse case was true for the females. Relative to SVL, L. oxycephala have larger heads than P. melisellensis. 3Bite force capacity was estimated by having the lizards bite on two metal plates, connected to a piezoelectric force transducer. Differences in maximal bite force between species and sexes paralleled differences in absolute head size. Differences in body size and head size explain the higher bite force of males (compared with females), but not the higher bite force of P. melisellensis (compared with L. oxycephala). Among individual lizards, bite force correlated with body size and head size. 4Prey handling efficiency, estimated by the time and number of bites needed to subdue a cricket in experimental conditions, also showed intersexual and interspecific variation. This variation corresponded to the differences in maximal bite capacity, suggesting that bite force is a determining factor in prey handling. Among individual lizards, both estimates of handling efficiency correlated with maximal bite force capacity. 5Faecal pellet analyses suggested that in field conditions, males of both sexes select larger and harder prey than females. There was no difference between the species. The proportion of hard-bodied and large-sized prey items found in a lizard's faeces correlated positively with its bite force capacity. 6It is concluded that differences in head and body size, through their effect on bite force capacity, may affect prey selection, either directly, or via handling efficiency. [source] State-dependent fertility in pinnipeds: contrasting capital and income breedersFUNCTIONAL ECOLOGY, Issue 5 2000I. L. Boyd Abstract 1.,The study tested the hypothesis that the occurrence of pregnancy in mammals that are capital breeders will be most closely related to state variables that are indices of food stores. Income breeders would not be expected to have the same relationship. 2.,The study examined the relationships between mass, time of year, age and body length with the occurrence of pregnancy in three species of pinniped. This included two capital breeders (Crabeater Seal, Lobodon carcinophagus Hombron & Jacquinot, and Grey Seal, Halichoerus grypus Fabricius) and one income breeder (Antarctic Fur Seal, Arctocephalus gazella Peters). Multiple logistic regression analysis was used to examine the relationships and the interactions between the different state variables. 3.,In both the capital breeders the state variables used in the study explained approximately twice the amount of variability (55% compared with 25%) in the occurrence of pregnancy than in the income breeder. Mass was the dominant state variable among both the capital breeders whereas in the income breeder mass was less important both relative to other state variables and in absolute terms. The results support the conclusion that the occurrence of pregnancy in capital breeders is more sensitive to body reserves than it is in income breeders. 4.,The results also support the conclusion that life histories are the end result of a variety of functional responses to different state variables that have differing degrees of influence. In particular a size-structured approach to studies of population dynamics in pinnipeds may be a more informative way of predicting population responses to environmental variability than the more traditional age-structured approach. [source] The Haiti Earthquake: a salutary lesson in (non) earthquake engineeringGEOLOGY TODAY, Issue 2 2010Peter Styles A devastating earthquake of magnitude 7 struck very close and almost beneath Port au Prince the capital of Haiti, the western half of the island of Hispaniola, early in the morning of Tuesday, 12 January 2010 (Fig. 1). While in absolute terms this was by no means the largest earthquake recorded this year globally, the death toll is around 230 000, making it one of the world's worst earthquakes in terms of casualties in recorded history, with almost uncountable economic loss to one of the poorest countries in the world. Figure 1. Intensity map of 2010 Haiti earthquake (Image: USGS). [source] On the Dynamics of Basic Growth Models: Ratio Stability vs.GERMAN ECONOMIC REVIEW, Issue 4 2009Convergence, Divergence in State Space Balanced growth; convergence; divergence; state space dynamics; ratio stability Abstract. We show for a class of basic growth models that convergence in ratios does not imply the pathwise convergence to the corresponding balanced growth path in the state space. We derive conditions on parameters and on the elasticity of the savings function for convergence or divergence and apply our results to the Solow model, an augmented Solow model as well as to an optimal growth model. An implication for the convergence debate is that two economies that differ only in the initial capital stock and converge in per capita terms might diverge to infinity in absolute terms. [source] C3 grasses have higher nutritional quality than C4 grasses under ambient and elevated atmospheric CO2GLOBAL CHANGE BIOLOGY, Issue 9 2004Raymond V. Barbehenn Abstract Grasses with the C3 photosynthetic pathway are commonly considered to be more nutritious host plants than C4 grasses, but the nutritional quality of C3 grasses is also more greatly impacted by elevated atmospheric CO2 than is that of C4 grasses; C3 grasses produce greater amounts of nonstructural carbohydrates and have greater declines in their nitrogen content than do C4 grasses under elevated CO2. Will C3 grasses remain nutritionally superior to C4 grasses under elevated CO2 levels? We addressed this question by determining whether levels of protein in C3 grasses decline to similar levels as in C4 grasses, and whether total carbohydrate : protein ratios become similar in C3 and C4 grasses under elevated CO2. In addition, we tested the hypothesis that, among the nonstructural carbohydrates in C3 grasses, levels of fructan respond most strongly to elevated CO2. Five C3 and five C4 grass species were grown from seed in outdoor open-top chambers at ambient (370 ppm) or elevated (740 ppm) CO2 for 2 months. As expected, a significant increase in sugars, starch and fructan in the C3 grasses under elevated CO2 was associated with a significant reduction in their protein levels, while protein levels in most C4 grasses were little affected by elevated CO2. However, this differential response of the two types of grasses was insufficient to reduce protein in C3 grasses to the levels in C4 grasses. Although levels of fructan in the C3 grasses tripled under elevated CO2, the amounts produced remained relatively low, both in absolute terms and as a fraction of the total nonstructural carbohydrates in the C3 grasses. We conclude that C3 grasses will generally remain more nutritious than C4 grasses at elevated CO2 concentrations, having higher levels of protein, nonstructural carbohydrates, and water, but lower levels of fiber and toughness, and lower total carbohydrate : protein ratios than C4 grasses. [source] INEQUALITY, INCOMPLETE CONTRACTS, AND THE SIZE DISTRIBUTION OF BUSINESS FIRMS,INTERNATIONAL ECONOMIC REVIEW, Issue 2 2010Thomas Gall This article analyzes the effects of intrafirm bargaining on the formation of firms in an economy with imperfect capital markets and contracting constraints. In equilibrium, wealth inequality induces a heterogeneous distribution of firm sizes, allowing for firms both too small and too large in terms of technical efficiency. The findings connect well to empirical facts such as the missing middle of firm-size distributions in developing countries. The model can encompass a nonmonotonic relationship between aggregate output and inequality. It turns out that an inflow of capital may indeed decrease output in absolute terms. [source] Patterns of weight change after treatment for bulimia nervosaINTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 1 2004Frances A. Carter Abstract Objective The current study examined changes in weight and body mass index (BMI) at 5-year follow-up among women treated for bulimia nervosa. Method The study comprised 80 women who had participated in a randomized clinical trial evaluating cognitive-behavior therapy for bulimia nervosa. The women had attended assessments at posttreatment and at 5-year follow-up while not pregnant. Results Changes in mean weight and BMI between posttreatment and 5-year follow-up were small in absolute terms and were not statistically significant. However, by the 5-year follow-up, approximately one half of the participants had either lost (31%) or gained (18%) 5 or more kilograms or were underweight (31%) or overweight (24%) as defined by BMI. Univariate analyses suggest that it is the patients who gain weight over the follow-up that are distinctive. Patients who gained weight over the follow-up were more likely to have commenced menstruation at a younger age, to have a lifetime history of being heavier, and to have been heavier and more dissatisfied with their body at pretreatment, posttreatment, and at 5-year follow-up. Conclusion Five years after treatment for bulimia nervosa, approximately one half of the participants had changed substantially in weight. For those who had changed, weight loss was more common than weight gain. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 12,21, 2004. [source] Corporate Cash Policy and How to Manage it with Stock RepurchasesJOURNAL OF APPLIED CORPORATE FINANCE, Issue 3 2008Amy Dittmar At the end of 2004 total U.S. corporate cash holdings reached an all-time high of just under $2 trillion,an amount equal to roughly 15% of the total U.S. GDP. And during the past 25 years, average cash holdings have jumped from 10% to 23% of total corporate assets. But at the same time their levels of cash have risen, U.S. companies have paid out dramatically increasing amounts of cash to buy back shares. This article addresses the following questions: What accounts for the dramatic increase in the average level of corporate cash holdings since 1980? And why do some companies keep so much cash (with one fourth of U.S. firms holding cash amounting to at least 36% of total assets) while others have so little (with another quarter having less than 3%)? Why do companies pay out excess cash in the form of stock repurchases (rather than, say, dividends), and what explains the significant increase in repurchases (both in absolute terms and relative to dividends) over time? The author begins by arguing that cash reserves provide companies with a buffer against possible shortfalls in operating profits,one that, especially during periods of financial trouble, can be used to avoid financial distress or provide funding for promising projects that might otherwise have to be put off. Such buffers are particularly valuable in the case of smaller, riskier companies with lots of growth opportunities and limited access to capital markets. And the dramatic increase in corporate cash holdings between 1980 and the present can be attributed mainly to an increase in the risk of publicly traded companies,an increase in risk that reflects in part a general increase in competition, but also a notable change over time in the kinds of companies (smaller, newer, less profitable, non-dividend paying firms) that have chosen to go public. At the other end of the corporate spectrum are large, relatively mature companies with limited growth opportunities. Although such companies tend to produce considerable free cash flow, they also tend to retain relatively small amounts of cash (as a percentage of total assets), in part because of shareholder concern about the corporate "free cash flow problem",the well-documented tendency of such companies to destroy value through overpriced (often diversifying) acquisitions and other misguided attempts to pursue growth at the expense of profitability. For companies with highly predictable earnings and investment plans, dividends provide one means of addressing the free cash flow problem. But for companies with more variable earnings and less predictable reinvestment, open-market stock repurchases provide a more flexible means of distributing cash to shareholders. Unlike the corporate "commitment" implied by dividend payments, an open market stock repurchase program creates what amounts to an option but not an obligation to distribute funds. The value of such flexibility, which increases during periods of increased risk and uncertainty, explains much of the apparent substitution of repurchases for dividends in recent years. [source] Habitat use, migration pattern and population dynamics of chevron snakehead Channa striata in a rainfed rice farming landscapeJOURNAL OF FISH BIOLOGY, Issue 2005E. Amilhat Habitat use, migration, mortality and growth of the chevron snakehead Channa striata in a rainfed rice farming landscape of north-east Thailand were studied through a tagging experiment. A total of 751 fish were captured, tagged and released during three distinct events in the late dry season, and in the beginning and at the end of the wet season. Rice fields provided the major wet season habitat for C. striata. Small trap ponds built to provide dry season habitat on farms provided 20% of catches and, if not harvested, could increase recruitment to the spawning stock by >30% despite accounting for <1% of dry season habitat by area. Migrations were localized (mostly <500 m). Up-migration from perennial to seasonal water bodies at the beginning of the wet season involved longer distances and took place over a longer time than down-migration at the end of the wet season. Natural mortality rates were extremely high, particularly during the period of down-migration. Fishing mortality rates were high in absolute terms, but contributed only 6,36% to the total mortality. Growth was seasonal with a maximum towards the end of the wet season. Snakeheads have successfully colonized the rainfed rice farming landscape, where populations can withstand intensive exploitation and respond well to aquatic habitat management on farmland. [source] "Kana sora ratswa ngaritswe": African Nationalists and Black Workers , The 1948 General Strike in Colonial ZimbabweJOURNAL OF HISTORICAL SOCIOLOGY, Issue 3 2000Ian Phimister For almost two weeks in April 1948 colonial Zimbabwe's two major cities, as well as smaller towns, mines and farms were convulsed by mass unrest. Although the causes of the General Strike have long been recognised as having their origins in the urban squalor and rampant inflation of the immediate post-war era, there is little agreement about either its organisation or its significance. Recent interventions in the debate have tended to strengthen existing prejudices. This paper advances four linked propositions which radically reformulate previous positions: that, while the development of secondary industry and the related growth of colonial Zimbabwe's urban areas were both relatively large by the modest standards of Sub-Saharan African, the scale was small in absolute terms; that these processes and their social consequences differed considerably between Bulawayo and Salisbury; that that the limited scale of these processes often meant that parochial concerns were more important than national issues; and that while all of this facilitated a greater degree of control over events in Bulawayo, if not in Salisbury, by an elite leadership than some writers have conceded, these events did not amount to a colony-wide General Strike. [source] Relative power and influence strategy: the effects of agent/target organizational power on superiors' choices of influence strategiesJOURNAL OF ORGANIZATIONAL BEHAVIOR, Issue 2 2002Anit Somech The present study examined superiors' tendency to utilize different top,down influence strategies according to their evaluation of their own power relative to that of their subordinates. Four hundred and fifty-five subordinates (schoolteachers) from different schools described the extent to which their superiors used each item of the influence strategy questionnaire to influence them, while their immediate superiors evaluated superior's power and subordinate's power. Overall, superiors tended to use soft and rational strategy more often than hard strategy. However, regarding the parameter of relative power, the results indicated that the agent's power, as well as the target's power, affected the superior's choice of particular influence strategy. The results suggest that power should be discussed in relative rather than absolute terms. Copyright © 2001 John Wiley & Sons, Ltd. [source] Screening of cosolvents for a supercritical fluid: A fully predictive approachAICHE JOURNAL, Issue 3 2002K. Abaroudi Solubility of solids was modeled in modified supercritical carbon dioxide as a predictive method. The Peng-Robinson equation of state was used to characterize the ternary systems using the one-fluid van der Waals rules. Ternary mixture parameters k12, k23, and k13 were obtained from the binary mixtures using Wong-Sandler mixing rules or the linear combination of Vidal-Michelsen mixing rules together with UNIFAC as required as a fully predictive tool for the liquid activity coefficients. When this method was applied to predict the solubility of ,-naphthol in CO2 modified with 6% and 10% toluene, values for the predicted solubility were very similar to the measured ones, with deviations of 9.6 and 26.3%, respectively. However, when the method was applied to the data of Simon et al. who examined six common cosolvents, the results were not as good in absolute terms, but the solvents were sorted in about the same order as found experimentally. The method provides quite an approximate guide to judge the most effective cosolvent from several candidates using a fully predictive methodology. [source] Water balance modelling of (Sub-)Arctic rivers and freshwater supply to the Barents Sea BasinPERMAFROST AND PERIGLACIAL PROCESSES, Issue 3 2005Eduard Koster Abstract Recently, changes in the freshwater supply by rivers to the Arctic Ocean have attracted a great deal of attention. However, quantitative assessments of changes in the annual and seasonal discharge regime of (Sub-)Arctic rivers resulting from climate change are still far from accurate. The sensitivity of discharge to potential changes in climate in two river catchments of intermediate size (104,105,km2), the Tana River in northern Fennoscandia and the Usa River in northern Russia, both draining into the Barents Sea Basin, was evaluated using a spatially distributed water balance model. The tentative results show that discharge amounts during peak flow might remain more or less the same or show a slight increase. However, peakflow events are expected to occur about 20 days or more earlier in spring. Concerning annual discharge amounts a strong increase of 25% for the Usa River and even 39% for the Tana River is simulated in conformity with projected increases in precipitation. Obviously, the resulting increases of the annual freshwater influx from the Tana River (from 5.3 to 7.3,km3) and that of the Usa River (from 42 to 52,km3) into the Barents Sea are insignificant in absolute terms. But in relative terms they agree remarkably well with earlier estimates of changes in freshwater inflow by the very large (Sub-)Arctic rivers. Copyright © 2005 John Wiley & Sons, Ltd. [source] Regulation lite: The rise of emissions tradingREGULATION & GOVERNANCE, Issue 2 2008Robert Baldwin Abstract Emissions trading is the governmentally promoted hope for a sustainable world. In different contexts, trading regimes display varying potential , both in absolute terms and in comparison with other regulatory instruments. Emissions trading, however, is a device that raises urgent issues regarding its objectives, cost-effectiveness, fairness, transparency, and legitimacy. Its use places emphasis on its "acceptability" and the virtues of regulation that is "lite" because it is non-threatening to the most powerful interests. Emissions trading is resonant with assumptions that are highly contentious , notably that it is acceptable because it involves no losers, or because, in desperate global circumstances, we have no choice but to use it. There is a need to confront the difficult issues presented by emissions trading and to face the challenges of combining "market" and "democratic" systems of legitimization. It is also necessary to avoid taking refuge in all too comfortable beliefs in cumulative checks and balances. [source] The Relationship Between Cephalic Scales and Bones in Lizards: A Preliminary Microtomographic Survey on Three Lacertid SpeciesTHE ANATOMICAL RECORD : ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, Issue 2 2010David Costantini Abstract In the last two decades, there has been a great deal of interest in the morphology and anatomy of the lizard skull in an ecological and evolutionary perspective. However, the relationship between variations in many key anatomical features remains largely unknown. Using microtomography and geometric morphometrics, we examined the relationship between bones and scales associated with the parietal foramen in the three lizards species most common in the Italian peninsula: Podarcis muralis, P. sicula, and Lacerta bilineata. The imprints of the scales are clearly recognizable on the outer bone surface, and this may suggest a structural interaction between these elements. The temporal osteoderms are visible in the larger males and in the larger females of L. bilineata, but they are absent in the smaller specimens of L. bilineata and in all Podarcis specimens. Two parallel rows of pterygoid teeth are present in all the specimens of L. bilineata and are absent in the smaller male of L. bilineata and in both Podarcis species. Cheek osteoderms occurred only in the largest specimens of our sample (i.e., large L. bilineata), being possibly related to hyperostotic processes and densitometric thresholds more than to phylogeny. Minor differences may be also associated with the form of the parietal foramen. In absolute terms the parietal foramen tends to be largest in L. bilineata but in relation to skull length the foramen tends to be larger in P. muralis. In this latter species the foramen is also more elongated. In all three species the fronto-parietal suture occupies a similar location relatively to the scale spatial organization. A shared allometric pattern shows that the main vault enlargement can be localised at the areas anterior to the fronto-parietal suture, providing further information on the possible morphogenetic dynamics associated with the interaction between scales and bones around this structure. Anat Rec, 2010. © 2009 Wiley-Liss, Inc. [source] Income and Health Concentration in AustraliaTHE ECONOMIC RECORD, Issue 246 2003Duangkamon Chotikapanich This paper measures the concentration of ill-health among income groups in Australia using health survey data from 1989,90 (Australian Bureau of Statistics 1991) and 1995 (Australian Bureau of Statistics 1997), which contain responses on self-assessed health status and gross personal income. The technique of direct standardisation is used to control for the influence on health status of gender and age. Comparisons of the concentration of ill-health over time and between males and females and persons living in rural and urban areas are reported. For both surveys and all groups, we find that ill-health is concentrated among lower income groups. Concentration measures of ill-health are higher (in absolute terms) for men than for women. In all categories apart from women, the concentration measures fell between 1989,90 and 1995 surveys. [source] Social influences on the development of foraging behavior in free-living common marmosets (Callithrix jacchus)AMERICAN JOURNAL OF PRIMATOLOGY, Issue 12 2006Nicola Schiel Abstract In this study we investigated the extent and pattern of social influences (i.e., the use of a conspecific as a model) on the foraging behavior of immature, wild common marmosets (Callithrix jacchus) as a function of the age of individuals. We compared the foraging activities and interactions with subadult and adult group members (older than 15 months) of young infants (1,2 months old), older infants (3,4 months old), and juveniles (5,10 months old). In addition to measuring the intensities of model-independent foraging (MIF) and merely paying attention to the model's foraging activities, we examined the frequencies of three types of model-dependent foraging (MDF): "follow the model", "manipulate the same object", and "forage together". We found that older infants were the most attentive and most socially-influenced foragers among the three age categories in absolute terms, but were not more attentive than young infants given their low foraging activity. Juveniles, in contrast, tended to have reduced overall foraging intensity compared to infants, but showed relatively more MDF in cases in which they observed subadult or adult models. Female models appeared to be more attractive than male models. These findings suggest that infants are generally more attentive to the foraging behavior of subadults and adults than juveniles, with the latter being more influenced when they had observed a model before. These subtle age-dependent effects of social foraging not only extend the assumption that young primates seek information from adults, they also suggest a complex interplay among physical and cognitive maturation, independence, and social dynamics. Am. J. Primatol. 68:1,11, 2006. © 2006 Wiley-Liss, Inc. [source] Black-Scholes-Merton revisited under stochastic dividend yieldsTHE JOURNAL OF FUTURES MARKETS, Issue 7 2006Abraham LiouiArticle first published online: 9 MAY 200 European options are priced in a framework ŕ la Black-Scholes-Merton, which is extended to incorporate stochastic dividend yield under a stochastic mean,reverting market price of risk. Explicit formulas are obtained for call and put prices and their Greek parameters. Some well-known properties of the Black-Scholes-Merton formula fail to hold in this setting. For example, the delta of the call can be negative and even greater than one in absolute terms. Moreover, call prices can be a decreasing function of the underlying volatility although the latter is constant. Finally, and most importantly, option prices highly depend on the features of the market price of risk, which does not need to be specified at all in the standard Black-Scholes-Merton setting. The results are simulated in order to assess the economic impact of assuming that the dividend yield is deterministic when it is actually stochastic, as well as to assess the economic importance of the features of the market price of risk. © 2006 Wiley Periodicals, Inc. Jrl Fut Mark 26:703,732, 2006 [source] Adaptations in placental nutrient transfer capacity to meet fetal growth demands depend on placental size in miceTHE JOURNAL OF PHYSIOLOGY, Issue 18 2008P. M. Coan Experimental reduction in placental growth often leads to increased placental efficiency measured as grams of fetus produced per gram of placenta, although little is known about the mechanisms involved. This study tested the hypothesis that the smallest placenta within a litter is the most efficient at supporting fetal growth by examining the natural intra-litter variation in placental nutrient transfer capacity in normal pregnant mice. The morphology, nutrient transfer and expression of key growth and nutrient supply genes (Igf2P0, Grb10, Slc2a1, Slc2a3, Slc38a1, Slc38a2 and Slc38a4) were compared in the lightest and heaviest placentas of a litter at days 16 and 19 of pregnancy, when mouse fetuses are growing most rapidly in absolute terms. The data show that there are morphological and functional adaptations in the lightest placenta within a litter, which increase active transport of amino acids per gram of placenta and maintain normal fetal growth close to term, despite the reduced placental mass. The specific placental adaptations differ with age. At E16, they are primarily morphological with an increase in the volume fraction of the labyrinthine zone responsible for nutrient exchange, whereas at E19 they are more functional with up-regulated placental expression of the glucose transporter gene, Slc2a1/GLUT1 and one isoform the System A family of amino acid transporters, Slc38a2/SNAT2. Thus, this adaptability in placental phenotype provides a functional reserve capacity for maximizing fetal growth during late gestation when placental growth is compromised. [source] Atorvastatin increases expression of low-density lipoprotein receptor mRNA in human circulating mononuclear cellsCLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Issue 4 2010Anothai Pocathikorn Summary 1.,3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, or statins, are commonly used to lower plasma cholesterol levels. HMGCR and the low-density lipoprotein (LDL) receptor (LDLR) are of central importance to cholesterol homeostasis and yet there is a paucity of data on the effect of statins on the regulation of the LDLR and HMGCR in humans. 2.,In the present study, we examined the effect of atorvastatin on the expression of HMGCR, LDLR and LDLR-related protein (LRP) mRNA in circulating mononuclear cells. Twelve human volunteers were treated with atorvastatin, 20 mg/day for 4 weeks. 3.,Atorvastatin decreased plasma total and LDL,cholesterol by 29% (P < 0.0001) and 41% (P < 0.001), respectively, and increased LDLR mRNA abundance, in absolute terms, by 35% (P < 0.001) and 31% (P < 0.0001) and 37% (P = 0.01) relative to reference GAPDH and ,-actin mRNA, respectively. In contrast, atorvastatin had no significant effect on LRP or HMGCR mRNA levels. 4. The increase in LDLR mRNA in circulating mononuclear cells agrees with the few human studies conducted, as well as with in vitro and animal studies, whereas the unchanged HMGCR mRNA is consistent with the hepatic specificity of atorvastatin. The present study firmly documents an increase in LDLR mRNA levels in response to statin administration in normal humans. [source] | |||||||||||||||||||||||||