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Cannabis
Kinds of Cannabis Terms modified by Cannabis Selected AbstractsESTIMATING HARMFUL EFFECTS OF CANNABIS AND USE FOR POLICY MAKERS SHIFTING FROM ONE MISTAKE TO THE NEXT?ADDICTION, Issue 8 2010HANS-ULRICH WITTCHEN No abstract is available for this article. [source] HIGH POTENCY CANNABIS: THE FORGOTTEN VARIABLEADDICTION, Issue 10 2005NEIL SMITH No abstract is available for this article. [source] THE CANNABIS AND PSYCHOSIS CONNECTION QUESTIONED: A COMMENT ON FERGUSSON ET AL.ADDICTION, Issue 5 2005No abstract is available for this article. [source] Illicit substance use and its correlates in first episode psychosisACTA PSYCHIATRICA SCANDINAVICA, Issue 5 2010R. Mazzoncini Mazzoncini R, Donoghue K, Hart J, Morgan C, Doody GA, Dazzan P, Jones PB, Morgan K, Murray RM, Fearon P. Illicit substance use and its correlates in first episode psychosis. Objective:, To determine if substance use (particularly cannabis) is more frequent among first episode psychosis patients and associated with a more problematic clinical presentation. Method:, All first episode psychosis (FEP) patients presenting to secondary services were recruited from London and Nottingham, over 2 years, in the Aetiology and Ethnicity of Schizophrenia and Other Psychoses study broad framework. Clinical and sociodemographic variables were assessed using a set of standardized instruments. A schedule was created to retrospectively collate substance use data from patients, relatives and clinicians. Results:, Five hundred and eleven FEP were identified. They used three to five times more substances than general population. Substance use was associated with poorer social adjustment and a more acute mode of onset. Cannabis use did not affect social adjustment, but was associated with a more acute mode of onset. Conclusion:, Cannabis has a different impact on FEP than other substances. Large epidemiological studies are needed to disentangle cannabis effect. [source] Cannabis and harm reductionDRUG AND ALCOHOL REVIEW, Issue 1 2000WENDY SWIFT First page of article [source] The Cannabis Use Problems Identification Test (CUPIT): development, reliability, concurrent and predictive validity among adolescents and adultsADDICTION, Issue 4 2010Jan Bashford ABSTRACT Aims To describe the empirical construction and initial validation of the Cannabis Use Problems Identification Test (CUPIT), a brief self-report screening instrument for detection of currently and potentially problematic cannabis use. Design In a three-phase prospective design an item pool of candidate questions was generated from a literature review and extensive expert consultation. The CUPIT internal structure, cross-sectional and longitudinal psychometric properties were then systematically tested among heterogeneous past-year users. Participants Volunteer participants were 212 high-risk adolescents (n = 138) and adults (n = 74) aged 13,61 years from multiple community settings. Measurements The comprehensive assessment battery included several established measures of cannabis-related pathology for CUPIT validation, with DSM-IV/ICD-10 diagnoses of cannabis use disorders as criterion standard. Findings Sixteen items loading highly on two subscales derived from principal components analysis exhibited good to excellent test,retest (0.89,0.99) and internal consistency reliability (0.92, 0.83), and highly significant ability to discriminate diagnostic subgroups along the severity continuum (non-problematic, risky, problematic use). Twelve months later, baseline CUPIT scores demonstrated highly significant longitudinal predictive utility for respondents' follow-up diagnostic group membership. Receiver operating characteristic (ROC) analysis identified a CUPIT score of 12 to be the optimal cut-point for maximizing sensitivity for both currently diagnosable cannabis use disorder and those at risk of meeting diagnostic criteria in the following 12 months. Conclusions The CUPIT is a brief cannabis screener that is reliable, valid and acceptable for use across diverse community settings and consumers of all ages. The CUPIT has clear potential to assist with achievement of public health goals to reduce cannabis-related harms in the community. [source] Cannabis and crime: findings from a longitudinal studyADDICTION, Issue 1 2010Willy Pedersen ABSTRACT Aim To examine the association between cannabis use during adolescence and young adulthood, and subsequent criminal charges. Methods Data were obtained from the Young in Norway Longitudinal Study. A population-based sample (n = 1353) was followed from 13 to 27 years of age. Data were gathered on cannabis use, alcohol consumption and alcohol problems, and use of other illegal substances such as amphetamines, cocaine and opiates. In addition, extensive information on socio-demographic, family and personal factors was collected. This data set was linked to individual-level information from official Norwegian crime statistics. Findings We found robust associations between cannabis use and later registered criminal charges, both in adolescence and in young adulthood. These associations were adjusted for a range of confounding factors, such as family socio-economic background, parental support and monitoring, educational achievement and career, previous criminal charges, conduct problems and history of cohabitation and marriage. In separate models, we controlled for alcohol measures and for use of other illegal substances. After adjustment, we still found strong associations between cannabis use and later criminal charges. However, when eliminating all types of drug-specific charges from our models, we no longer observed any significant association with cannabis use. Conclusions The study suggests that cannabis use in adolescence and early adulthood may be associated with subsequent involvement in criminal activity. However, the bulk of this involvement seems to be related to various types of drug-specific crime. Thus, the association seems to rest on the fact that use, possession and distribution of drugs such as cannabis is illegal. The study strengthens concerns about the laws relating to the use, possession and distribution of cannabis. [source] The familial aggregation of cannabis use disordersADDICTION, Issue 4 2009Kathleen R. Merikangas ABSTRACT Aims The aim of this paper is to examine the familial aggregation of cannabis use disorders and other psychiatric conditions among first-degree relatives and spouses of probands with a cannabis use disorder. Design Controlled family study methods. Setting Out-patient psychiatric clinics and the local community (same geographic area). Participants Two hundred and sixty-two probands with a life-time history of cannabis use disorder, alcohol dependence, anxiety disorders or no history of any disorder, and their first-degree relatives and spouses. Measurements Cannabis use disorders and other DSM-III-R disorders in the relatives and spouses using the Schedule for Affective Disorders and Schizophrenia. Findings Results reveal an elevated risk of life-time history of cannabis use disorders among siblings [odds ratio (OR: 3.6), adult offspring (OR): 6.9], and spouses (OR: 4.4) of probands with cannabis use disorders. There is a latent familial factor underlying cannabis use disorders that was shared partially with alcohol abuse/dependence. Comorbid mood and anxiety disorders aggregated independently from cannabis use disorders in families. Equal elevation in the magnitude of the association among the first-degree adult relatives and spouses of probands with a cannabis use disorder suggests the probable contribution of both environmental and genetic factors. Conclusions These findings support a family-based approach to drug abuse intervention and the importance of future research concerning environmental mediators of familial transmission of drug abuse. [source] Drug use and perceived treatment need among newly sentenced prisoners in England and WalesADDICTION, Issue 2 2009Duncan Stewart ABSTRACT Aims To investigate pre-custody levels of drug use among newly sentenced prisoners and factors associated with perceived drug treatment need. Design, setting and participants A sample of 1457 prisoners was recruited to a general purpose longitudinal survey of convicted prisoners starting a new sentence. Measurements Data were collected by structured interviews on reception to prison. Measures were taken of illicit drug use, drug treatment history, current treatment needs, psychological health and a range of social problems. Findings Life-time use of heroin, crack cocaine, cocaine powder, amphetamines or cannabis was reported by 79% of prisoners. Cannabis was the drug reported most commonly, but approximately a third had used heroin or crack cocaine during the year before custody. Nearly half of recent drug users reported wanting help or support with a drug problem during their sentence. Dependence on heroin and cocaine, previous drug treatment, employment, accommodation and psychological health problems were all associated positively with perceived treatment need. Conclusions The prevalence of pre-custody drug use among this sample of newly sentenced prisoners was high. Because treatment need was associated with a range of drug, health and social factors, assessment and referral to appropriate interventions should occur as soon as possible on reception. Treatment should be coordinated with other services and support. [source] Cannabis and schizophrenia: model projections of the impact of the rise in cannabis use on historical and future trends in schizophrenia in England and WalesADDICTION, Issue 4 2007Matthew Hickman ABSTRACT Aims To estimate long-term trends in cannabis use and projections of schizophrenia assuming a causal relation between cannabis use and schizophrenia. Methods Trends in cannabis use were estimated from a national survey, 2003; and incidence of schizophrenia was derived from surveys in three English cities, 1997,99. A difference equation cohort model was fitted against estimates of schizophrenia incidence, trends in cannabis exposure and assumptions on association between cannabis and schizophrenia. The model projects trends in schizophrenia incidence, prevalence and attributable fraction of cannabis induced schizophrenia. Results Between 1970 and 2002 cannabis exposure increased: incidence by fourfold; period prevalence by 10-fold; and use among under 18-year-olds by 18-fold. In 1997,99 incidence and prevalence of schizophrenia were 17 per 100 000 and 0.63% among men and 7.3 per 100 000 and 0.23% among women, respectively. If cannabis use causes schizophrenia, earlier increases in cannabis use would lead to increases in overall schizophrenia incidence and prevalence of 29% and 12% among men between 1990 and 2010. By 2010 model projections which assume an association between schizophrenia and light and heavy users suggest that approximately one-quarter of new schizophrenia cases could be due to cannabis, whereas if the association is twofold and confined to heavy cannabis users, then approximately 10% of schizophrenia cases may be due to cannabis. Conclusions If cannabis use causes schizophrenia, and assuming other causes are unchanged, then relatively substantial increases in both prevalence and incidence of schizophrenia should be apparent by 2010. More accurate data on cannabis consumption and future monitoring of schizophrenia are critical. [source] Associations between tobacco and cannabis use in remote indigenous populations in Northern AustraliaADDICTION, Issue 3 2005Alan R. Clough ABSTRACT Aims To assess whether cannabis use, recently taken up by many indigenous Australians in remote communities, has reinforced tobacco use. Design Cross-sectional study. Setting Three eastern Arnhem Land communities (Northern Territory, NT); total population = 3384, in 2001. Participants From 1247 people aged 17,36 years, 190 (120 males, 70 females) were opportunistically recruited. Measurements Self-reported life-time and current tobacco, cannabis and other substance use were confirmed by local health workers and using clinic records. Participants reported level of substance use, frequency and duration (years used). Associations with tobacco use were calculated (odds ratios: OR) using logistic regression with age, sex, alcohol use and a history of petrol sniffing as confounders. Findings In univariate analyses current tobacco users were more likely than non-users to be using cannabis (OR = 3.1, 1.5,6.2, P = 0.002) and this association remained in multivariate analyses (OR = 3.0, 1.4,6.8, P = 0.006). Tobacco use was associated with the number of years of cannabis use (P = 0.035). The likelihood that tobacco users were also cannabis users increased as quantity of cannabis used increased (P = 0.008). Current tobacco use was no more likely in those who initiated cannabis from 1998 onwards than in those who initiated cannabis before 1998 (OR = 1.1, 0.4,3.2, P = 0.881). One-third of life-time users of both tobacco and cannabis initiated their use at or near the same time, and very few of these (12%) had discontinued either cannabis or tobacco. Conclusions Cannabis appears to have influenced the continued use of tobacco in these populations with possible additional burdens for cardiovascular and respiratory diseases and challenges for interventions. [source] Cannabis condemned: the proscription of Indian hempADDICTION, Issue 2 2003Robert Kendell ABSTRACT Aims To find out how cannabis came to be subject to international narcotics legislation. Method Examination of the records of the 1925 League of Nations' Second Opium Conference, of the 1894 Report of the Indian Hemp Drugs Commission and other contemporary documents. Findings Although cannabis (Indian hemp) was not on the agenda of the Second Opium Conference, a claim by the Egyptian delegation that it was as dangerous as opium, and should therefore be subject to the same international controls, was supported by several other countries. No formal evidence was produced and conference delegates had not been briefed about cannabis. The only objections came from Britain and other colonial powers. They did not dispute the claim that cannabis was comparable to opium, but they did want to avoid a commitment to eliminating its use in their Asian and African territories. [source] Cannabis -based medicine in treating cancer-related anorexia-cachexia syndromeFOCUS ON ALTERNATIVE AND COMPLEMENTARY THERAPIES AN EVIDENCE-BASED APPROACH, Issue 1 2007Article first published online: 14 JUN 2010 [source] Cluster Attacks Responsive to Recreational Cannabis and DronabinolHEADACHE, Issue 6 2009Matthew S. Robbins MD Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache. [source] The effects of cannabis abuse on the symptoms of schizophrenia: Patient perspectivesINTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING, Issue 4 2008William F. Costain ABSTRACT:, This study explored explanatory models used by individuals with schizophrenia in relation to continuing cannabis abuse. Cannabis is known to exacerbate positive symptoms, compound the effects of negative symptoms, and lead to relapse, having a negative effect upon quality of life. If this is so, why would people choose to continue the drug use? Most previous studies exploring this phenomenon have used quantitative methodology where the questions asked have been preset by the researchers and the subjective experience of the patient has been minimized. Qualitative methodology was utilized in this study in order to give voice to the patients' perspectives, and contribute to the knowledge of the frameworks of meanings employed by patients. The majority of participants in this study did not perceive that they had a mental illness and they held strong beliefs regarding the usefulness of cannabis. They gave explanations for their continuing cannabis use that expanded the understanding from previous studies. These included that they sought the drug effects of cannabis use for clarity of voices, control of symptoms, to feel normal, perceived improvement in cognitive function, reduced psychological pain and increased energy. These beliefs may influence a person's adherence with treatment and their future cannabis use. This research has implications for clinical practice as clinicians may lack insight into the importance of the phenomenological beliefs of a person with schizophrenia. This lack of insight by the clinician into the phenomenological beliefs may impact on the development of a therapeutic relationship. [source] Revising the Cannabis Use Disorders Identification Test (CUDIT) by means of Item Response TheoryINTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue 3 2010Beatrice Annaheim Abstract Cannabis use among adolescents and young adults has become a major public health challenge. Several European countries are currently developing short screening instruments to identify ,problematic' forms of cannabis use in general population surveys. One such instrument is the Cannabis Use Disorders Identification Test (CUDIT), a 10-item questionnaire based on the Alcohol Use Disorders Identification Test. Previous research found that some CUDIT items did not perform well psychometrically. In the interests of improving the psychometric properties of the CUDIT, this study replaces the poorly performing items with new items that specifically address cannabis use. Analyses are based on a sub-sample of 558 recent cannabis users from a representative population sample of 5722 individuals (aged 13,32) who were surveyed in the 2007 Swiss Cannabis Monitoring Study. Four new items were added to the original CUDIT. Psychometric properties of all 14 items, as well as the dimensionality of the supplemented CUDIT were then examined using Item Response Theory. Results indicate the unidimensionality of CUDIT and an improvement in its psychometric performance when three original items (usual hours being stoned; injuries; guilt) are replaced by new ones (motives for using cannabis; missing out leisure time activities; difficulties at work/school). However, improvements were limited to cannabis users with a high problem score. For epidemiological purposes, any further revision of CUDIT should therefore include a greater number of ,easier' items. Copyright © 2010 John Wiley & Sons, Ltd. [source] Cannabis: What Makes University Students More or Less Likely to Use It?JOURNAL OF APPLIED BIOBEHAVIORAL RESEARCH, Issue 2 2006Frances V. O'Callaghan University students' motivations for using or not using cannabis were investigated. Students (n = 189) aged 17 to 29 years completed a survey to assess their intention to use cannabis and their beliefs about (a) advantages and disadvantages of using cannabis; (b) their perceptions of what significant others think they should do in relation to cannabis use; and (c) factors that might encourage them to use or not use cannabis. Two weeks later, they completed a follow-up survey asking about their actual behavior over the previous 2 weeks. Compared to non-users, users believed more strongly that cannabis would help them fit in with their friends, feel relaxed, forget their worries, and enjoy themselves. They also believed that their close friends, partner/spouse, siblings, and workmates would approve of their using cannabis. Users believed that certain factors (e.g., force of habit, wanting to relax, feeling stressed, being around other people using cannabis) would encourage them to use, while non-users rated work and study as strong reasons for not using cannabis. Beliefs that are relevant to users and non-users in education campaigns can be targeted to reduce the negative consequences of use in tertiary settings. [source] Cannabis, cocaine and jobsJOURNAL OF APPLIED ECONOMETRICS, Issue 7 2006Jan C. van Ours This paper uses a dataset collected among inhabitants of Amsterdam, to study the employment effects of the use of cannabis and cocaine. For females no negative effects of drug use on the employment rate are found. For males there is a negative correlation between past cannabis and cocaine use and employment. However, after correcting for the effect of unobserved personal characteristics there is no negative effect of cannabis use or cocaine use on the employment status of males. Copyright © 2006 John Wiley & Sons, Ltd. [source] Heavy Episodic Drinking and Alcohol Consumption in French Colleges: The Role of Perceived Social NormsALCOHOLISM, Issue 1 2010Lionel Riou França Background:, The effect of normative perceptions (social norms) on heavy episodic drinking (HED) behavior is well known in the U.S. college setting, but little work is available in other cultural contexts. The objective of this study is therefore to assess whether social norms of alcohol use are related to HED in France, taking account of other influential predictors. Methods:, A cross-sectional survey was carried out among 731 second-year university students in the Paris region to explore the role of 29 potential alcohol use risk factors. The probability of heavy episodic drinking and the frequency of HED among heavy episodic drinkers were modeled independently. Monthly alcohol consumption was also assessed. Results:, Of the students, 56% overestimate peer student prevalence of HED (37% for alcohol drinking prevalence). HED frequency rises with perceived peer student prevalence of HED. Other social norms associated with HED are perceived friends' approval of HED (increasing both HED probability and HED frequency) and perceived friend prevalence of alcohol drinking (increasing HED probability only). Cannabis and tobacco use, academic discipline, gender, and the number of friends are also identified as being associated with HED. Conclusions:, Overestimation of peer student prevalence is not uncommon among French university students. Furthermore, perceived peer student prevalence of HED is linked to HED frequency, even after adjusting for other correlates. Interventions correcting misperceived prevalences of HED among peer students have therefore the potential to reduce the frequency of HED in this population. [source] The Prevalence and Significance of Cannabis Use in Patients Prescribed Chronic Opioid Therapy: A Review of the Extant LiteraturePAIN MEDICINE, Issue 8 2009Gary M. Reisfield MD ABSTRACT Background., Cannabis is the most widely consumed illicit drug in the United States. Its use, particularly in early initiates, is associated with subsequent development of other drug and alcohol use disorders. Objective., The authors examined the prevalence of cannabis use and the association between cannabis use and aberrant opioid-related behaviors in patients prescribed chronic opioid therapy for persistent pain. Methods., PubMed was queried for studies of chronic opioid therapy in which aberrant opioid-related behaviors were quantitatively examined and in which cannabis use data (as determined by cannabinoid-positive urine drug tests) were extricable from that of other substances of abuse. Results., The prevalence of cannabis use among patients prescribed chronic opioid therapy in these studies ranged from 6.2% to 39%, compared with 5.8% in the general United States population. Furthermore, cannabis use in chronic opioid patients shows statistically significant associations with present and future aberrant opioid-related behaviors. Conclusion., Cannabis use is prevalent in patients prescribed chronic opioid therapy and is associated with opioid misuse. Further research is necessary to clarify the strength and the nature of the association between cannabis use and opioid misuse, and to address additional questions about the consequences of cannabis use in the context of chronic opioid therapy. [source] Association study between cannabinoid receptor gene (CNR1) and pathogenesis and psychotic symptoms of mood disorders,AMERICAN JOURNAL OF MEDICAL GENETICS, Issue 3 2001Shih-Jen Tsai MD Abstract Cannabis can induce mood change and sometimes psychotic symptoms in normal persons. In brain, the main active ingredient of cannabis acts via the cannabinoid CB1 receptor (CNR1) which is located on chromosome 6q14-15. Linkage studies have suggested the presence of a bipolar disorder susceptibility locus on chromosome 6q. In this population based association study, we tested the hypothesis that a microsatellite polymorphism in the promoter region of the CNR1 gene confers susceptibility to mood disorders and psychotic features. We genotyped the CNR1 gene is 154 mood disorder patients and 165 normal controls. The results showed that the triplet repeat polymorphism in the promoter region of the CNR1 gene was not likely to be involved in the pathogenesis or in the psychotic symptoms of mood disorders. © 2001 Wiley-Liss, Inc. [source] Treatment of Cannabis Use Disorders: A Review of the LiteratureTHE AMERICAN JOURNAL ON ADDICTIONS, Issue 5 2007Benjamin R. Nordstrom MD Cannabis is the most widely used illicit drug in the United States. Despite the fact that there are large numbers of people with cannabis dependence, relatively little attention has been paid to the treatment of this condition. This article seeks to critically review the existing literature about the various psychosocial and pharmacologic treatments of cannabis dependence. We begin with a discussion of the early treatment literature which draws primarily from anecdotal experience and open, uncontrolled trials and proceed through two recent, large, randomized controlled trials of psychotherapies for the treatment of cannabis dependence. We conclude that while a number of psychotherapies have been found to be effective in treating this disorder, with the exception of adding vouchers to reinforce negative urine toxicology screens, no form of psychotherapy has been found to be more effective than any other. In addition, we review the only two clinical pharmacotherapy trials for cannabis dependence as well as the pre-clinical laboratory pharmacotherapy trials in cannabis dependent individuals. We also review pertinent dual-diagnosis pharmacotherapy trials and discuss potential future directions in treatment research for the pharmacotherapy of cannabis dependence. [source] Cannabis and Fantasies of Development: Revaluing Relations through Land in Rural Papua New GuineaTHE AUSTRALIAN JOURNAL OF ANTHROPOLOGY, Issue 1 2007Jamon Alex Halvaksz Over the past decade, marijuana has become a significant element within Papua New Guinea's communities, revealing an important connection to the broader political economy. For young men, fluctuating commodity prices, the intermittent exploitation of mineral wealth and a reluctant tourist economy only gives them a taste for development. Marijuana seems to offer its permanence. Somewhere between the harsh reality of local economic and ecological futures young men near the town of Wau (Morobe Province) imagine themselves as successful entrepreneurs in the emerging drug trade. In particular, I consider how young men imagine the planting of this illicit crop as mediating tensions between acting individually and acting communally. While most have yet to take action on these fantasies, they provide insight into the development aspirations of rural Papua New Guineans. In this paper, I examine these development fantasies as they speak to a broader political economy and transformations of local landscapes throughout rural Pacific communities. [source] Economic Relationship Between Alcohol and Cannabis RevisitedTHE ECONOMIC RECORD, Issue 248 2004Jenny Williams Consuming cannabis in combination with alcohol is common among Australian cannabis users. This paper investigates whether the economic relationship between cannabis and alcohol is affected by the manner in which these two substances are used. Our results indicate that cannabis and alcohol are economic complements for all cannabis users, but this relationship is stronger for cannabis users who tend to use alcohol and cannabis together, whom we refer to as polysubstance users. Separate analysis by gender suggests that cannabis consumption by polysubstance and non-polysubstance using males is more responsive to changes in the full price of alcohol than their female counterparts. [source] Cannabis, Alcohol and Cigarettes: Substitutes or Complements?THE ECONOMIC RECORD, Issue 236 2001Lisa Cameron This paper uses individual level data from the National Drug Strategy Household Surveys to estimate the price responsiveness of participation in cannabis, alcohol and cigarette use. In addition to own price effects, we estimate cross price effects and the impact of decriminalizing cannabis use. We find that participation is responsive to own prices. There is some evidence that cannabis is a substitute for alcohol and a complement to cigarettes, and that alcohol and cigarettes are complements. The liberalization of cannabis laws in South Australia may have led to a temporary increase in cannabis use among the over-30 age group. [source] Medical Marijuana 2010: It's Time to Fix the Regulatory VacuumTHE JOURNAL OF LAW, MEDICINE & ETHICS, Issue 3 2010Peter J. Cohen This article examines the history of assigning a banned status to medical marijuana; describes the politics of medical marijuana research; provides evidence of the scientifically demonstrated efficacy and safety of Cannabis for certain pathologic conditions; analyzes several vaguely worded state statutes governing the recommendation, distribution, and use of "medical marijuana" that render its use open to abuse; and recommends the development and enforcement of statutory and regulatory reforms that would bring state oversight of this drug into agreement with stringent federal regulation of other controlled substances with proven medical utility. [source] Cannabis Use and Sexual HealthTHE JOURNAL OF SEXUAL MEDICINE, Issue 2pt1 2010Anthony M.A. Smith PhD ABSTRACT Introduction., Cannabis is the most commonly used illicit substance worldwide. Despite this, its impact on sexual health is largely unknown. Aim., The aim of this article is to examine the association between cannabis use and a range of sexual health outcomes. Main Outcome Measures., The main outcome measures include the number of sexual partners in the past year, condom use at most recent vaginal or anal intercourse, diagnosis with a sexually transmissible infection in the previous year, and the occurrence of sexual problems. Methods., Method used in this article includes a computer-assisted telephone survey of 8,656 Australians aged 16,64 years resident in Australian households with a fixed telephone line. Results., Of the 8,650 who answered the questions about cannabis use, 754 (8.7%) reported cannabis use in the previous year with 126 (1.5%) reporting daily use, 126 reported (1.5%) weekly use, and 502 (5.8%) reported use less often than weekly. After adjusting for demographic factors, daily cannabis use compared with no use was associated with an increased likelihood of reporting two or more sexual partners in the previous year in both men (adjusted odds ratio 2.08, 95% confidence interval 1.11,3.89; P = 0.02) and women (2.58, 1.08,6.18; P = 0.03). Daily cannabis use was associated with reporting a diagnosis of a sexually transmissible infection in women but not men (7.19, 1.28,40.31; P = 0.02 and 1.45, 0.17,12.42; P = 0.74, respectively). Frequency of cannabis use was unrelated to sexual problems in women but daily use vs. no use was associated with increased reporting among men of an inability to reach orgasm (3.94, 1.71,9.07; P < 0.01), reaching orgasm too quickly (2.68, 1.41,5.08; P < 0.01), and too slowly (2.05, 1.02,4.12; P = 0.04). Conclusions., Frequent cannabis use is associated with higher numbers of sexual partners for both men and women, and difficulties in men's ability to orgasm as desired. Smith AMA, Ferris JA, Simpson JM, Shelley J, Pitts M, and Richters J. Cannabis use and sexual health. J Sex Med 2010;7:787,793. [source] Cannabis and Endocannabinoids: ,The Old Man and the Teenagers'CHEMISTRY & BIODIVERSITY, Issue 8 2007Didier First page of article [source] History of Cannabis and Its Preparations in Saga, Science, and SobriquetCHEMISTRY & BIODIVERSITY, Issue 8 2007Ethan Abstract Cannabis sativa L. is possibly one of the oldest plants cultivated by man, but has remained a source of controversy throughout its history. Whether pariah or panacea, this most versatile botanical has provided a mirror to medicine and has pointed the way in the last two decades toward a host of medical challenges from analgesia to weight loss through the discovery of its myriad biochemical attributes and the endocannabinoid system wherein many of its components operate. This study surveys the history of cannabis, its genetics and preparations. A review of cannabis usage in Ancient Egypt will serve as an archetype, while examining first mentions from various Old World cultures and their pertinence for contemporary scientific investigation. Cannabis historians of the past have provided promising clues to potential treatments for a wide array of currently puzzling medical syndromes including chronic pain, spasticity, cancer, seizure disorders, nausea, anorexia, and infectious disease that remain challenges for 21st century medicine. Information gleaned from the history of cannabis administration in its various forms may provide useful points of departure for research into novel delivery techniques and standardization of cannabis-based medicines that will allow their prescription for treatment of these intractable medical conditions. [source] Computer-based psychological treatment for comorbid depression and problematic alcohol and/or cannabis use: a randomized controlled trial of clinical efficacyADDICTION, Issue 3 2009Frances J. Kay-Lambkin ABSTRACT Aims To evaluate computer- versus therapist-delivered psychological treatment for people with comorbid depression and alcohol/cannabis use problems. Design Randomized controlled trial. Setting Community-based participants in the Hunter Region of New South Wales, Australia. Participants Ninety-seven people with comorbid major depression and alcohol/cannabis misuse. Intervention All participants received a brief intervention (BI) for depressive symptoms and substance misuse, followed by random assignment to: no further treatment (BI alone); or nine sessions of motivational interviewing and cognitive behaviour therapy (intensive MI/CBT). Participants allocated to the intensive MI/CBT condition were selected at random to receive their treatment ,live' (i.e. delivered by a psychologist) or via a computer-based program (with brief weekly input from a psychologist). Measurements Depression, alcohol/cannabis use and hazardous substance use index scores measured at baseline, and 3, 6 and 12 months post-baseline assessment. Findings (i) Depression responded better to intensive MI/CBT compared to BI alone, with ,live' treatment demonstrating a strong short-term beneficial effect which was matched by computer-based treatment at 12-month follow-up; (ii) problematic alcohol use responded well to BI alone and even better to the intensive MI/CBT intervention; (iii) intensive MI/CBT was significantly better than BI alone in reducing cannabis use and hazardous substance use, with computer-based therapy showing the largest treatment effect. Conclusions Computer-based treatment, targeting both depression and substance use simultaneously, results in at least equivalent 12-month outcomes relative to a ,live' intervention. For clinicians treating people with comorbid depression and alcohol problems, BIs addressing both issues appear to be an appropriate and efficacious treatment option. Primary care of those with comorbid depression and cannabis use problems could involve computer-based integrated interventions for depression and cannabis use, with brief regular contact with the clinician to check on progress. [source] | |||||||||||||||||||||||||