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Bronchial Airways (bronchial + airway)
Selected AbstractsAlveolar Macrophage Graded Hemosiderin Score from Bronchoalveolar Lavage in Horses with Exercise-Induced Pulmonary Hemorrhage and ControlsJOURNAL OF VETERINARY INTERNAL MEDICINE, Issue 3 2002Michele Y. Doucet The objective of this study was to determine if a quantitative scoring system for evaluation of hemosiderin content of alveolar macrophages obtained by bronchoalevolar lavage provides a more sensitive test for the detection of exercise-induced pulmonary hemorrhage (EIPH) in horses than does endoscopy of the lower airways. A sample population composed of 74 Standardbred racehorses aged 2,5 years was used. Horses were grouped as either control (EIPH-negative) or EIPH-positive based on history and repeated postexertional endoscopic evaluation of the bronchial airways. Bronchoalveolar lavage was performed and cytocen-trifuge slides were stained with Perl's Prussian blue. Alveolar macrophages were scored for hemosiderin content by a method described by Golde and associates to obtain the total hemosiderin score (THS). Test performance criteria were determined with a contingency table. All subjects had some degree of hemosiderin in the alveolar macrophages, regardless of group. The distribution of cells among the different grades followed a significantly different pattern for the control group versus horses with EIPH (P < .05). When using a THS of 75 as a cutoff point, the THS test was found to have a sensitivity of 94% and a specificity of 88%. The level of agreement beyond chance, between the EIPH status and the THS test result was very good (Cohen's kappa = 74%). The conclusion was made that careful assessment and scoring of alveolar macrophages for hemosiderin by means of the Golde scoring system shows promise as a more sensitive approach than repeated postexertional endoscopy alone to detect EIPH. [source] Relaxation and guided imagery as an intervention for children with asthma: A replicationPSYCHOLOGY IN THE SCHOOLS, Issue 7 2005Robin L. Dobson Asthma is a pervasive inflammatory disorder of the bronchial airways that causes the normal functioning of the airways to become overreactive. This disorder affects approximately 8 million children in schools per year and accounts for a significant amount of absences. Researchers have speculated that pharmacological interventions are alone insufficient or overaggressive in treating asthma, and numerous studies have demonstrated a connection between emotions and asthma. It has therefore been suggested that psychological interventions may be appropriate for this population. One such intervention, relaxation and guided imagery (RGI), that incorporates mental representations as well as the senses in a process of relaxing all the parts of the body has been shown to be effective with children with asthma. The current study served as a replication and extension of this previous research. The purpose of the investigation was to examine the effectiveness of RGI with an elementary school sample as well as determine the overall improvement in happiness, anxiety, and quality of life of the participants. Results demonstrated that RGI significantly improved the lung functioning of 3 out of 4 participants in the study. Furthermore, overall happiness improved for 1 participant in the study, state anxiety decreased for 2 of the 4 participants, and trait anxiety decreased for all 4 participants. © 2005 Wiley Periodicals, Inc. Psychol Schs 42: 707,720, 2005. [source] Morphological Analysis of the Lung of Neonatal YakANATOMIA, HISTOLOGIA, EMBRYOLOGIA, Issue 2 2010B. Yang Summary With 20 figures and 5 tables Although yaks play an important role as companion or pack and draught animals on Chinese plateaus in alpine and sub-alpine regions, morphological studies and anatomical data on the lung of yak are sparse. To provide anatomical descriptions and morphometric data, 10 one-day-old yaks were examined by means of dissection, light and electron microscopy. The measurements of lung were made on dissected specimens and histological sections. Unequal dichotomous branching was demonstrated in the dissected tracheobronchial tree. The diameters of bronchial airways and height of epithelium were measured, and showed that the variation of diameters in airways was always greater than that of height of epithelium. In addition, the thickness of muscularis, cartilage and adventitia was examined, as well as the number of goblet and Clara cells in airways. Ultrastructural studies showed that the surface epithelium was mainly composed of goblet, ciliated, Clara and basal cells, similar to that in other domestic animals. Under electron microscope, two distinctive types of ciliated cells could be seen in the tracheobronchial epithelium. The first type contained some mitochondria, distended smooth endoplasmic reticulum (SER), little rough endoplasmic reticulum (RER) and numerous vacuoles in electron-lucent cytoplasm. The second type had dense cytoplasm with abundant mitochondria, RER and no vacuoles. Both types were rich of glycogen granules. The goblet cells in neonatal yak lung had the following characteristic features: dentate nucleus in dense cytoplasm, with stacks of RER and numerous dense membrane-bounded mucous droplets, which were round or oval, often with an electron-lucent core. The droplets were not confluent. Glycogen granules were numerous, and Golgi complex was occasionally present. Clara cells were dome-shaped and usually protruded into the airway lumen. Large amounts of SER and many secretory droplets were found within the cytoplasm. Several typical ,clefts' were also found in the cytoplasm. [source] Airway microvascular extravasation and luminal entry of plasmaCLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, Issue 6 2003Lennart Greiff Summary Extravasation of plasma from postcapillary venules is a specific in vivo response to inflammatory insults. In the nasal and bronchial airways, extravasated plasma has a widespread distribution in the lamina propria, between the epithelial cells and in the airway lumen. This feature, in combination with the fact that the process involves extravasation of bulk plasma, with all peptides and proteins of plasma, indicates that plasma exudation contributes to the dramatic change of the mucosal milieu that characterizes airway inflammation. Accordingly, this process is of key importance to conditions such as allergic rhinitis and asthma. The means by which extravasated plasma participates in mucosal defence is physiological in the sense that it may operate on the surface of the epithelium without impairing its function as an absorption barrier. The flow of plasma into the airway lumen may thus wash away unwanted material from inter-epithelial cell spaces, exuded binding proteins may bind unwanted solutes non-specifically and extravasated immunoglobulins may neutralize allergens. In addition to the role as defence mechanism, extravasated plasma components may act as important pro-inflammatory factors. Furthermore, experimental data as well as observations in natural disease suggest that luminal levels of plasma proteins can be employed as an accessible index reflecting to what degree the airway mucosa is affected by inflammatory processes. [source] | ||||||||||