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Biologically Active Compounds (biologically + active_compound)
Selected AbstractsAlkoxy-5-nitrosopyrimidines: Useful Building Block for the Generation of Biologically Active CompoundsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 20 2010Antonio Marchal Abstract Several alkoxy-5-nitrosopyrimidines were synthesised and high regioselective and sequential nucleophilic aromatic substitution of methoxy groups in 2-amino-4,6-dimethoxy-5-nitrosopyrimidine was observed. The approach was applied to the synthesis of valuable polyfunctionalised aminopyrimidines capable of mimicking fused heterobicyclic derivatives of biological interest. In addition, new compounds were evaluated as antivirals and their usefulness as synthetic intermediates was demonstrated. [source] Amidrazones as Precursors of Biologically Active Compounds , Synthesis of Diaminopyrazoles for Evaluation of Anticancer ActivityARCHIV DER PHARMAZIE, Issue 1 2006Maria Teresa Cocco Abstract The regioselectivity of coupling phenyl isocyanate to 3-(2-acylhydrazino)-3-aminopropenenitriles and ethyl 3-(2-acylhydrazino)-3-aminopropenoates as simple access to aminopyrazole derivatives, endowed with potential antitumoral activity, is reported. 3-(2-Acylhydrazino)-3-aminopropenenitriles react with phenyl isocyanate to afford 3-amino-3-(2-acylhydrazino)-2-phenylaminocarbonyl-2-propenenitriles. These key intermediates were cyclized into 3,5-diaminopyrazole-4-carboxamide derivatives. Preliminary results of poor antiproliferative activities of these compounds are also reported. [source] ChemInform Abstract: Expedient Asymmetric Synthesis of (2S,3S)-Boc-phenylalanine Epoxide (X), a Key Intermediate for the Synthesis of Biologically Active Compounds.CHEMINFORM, Issue 12 2010Ramon Badorrey Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: The Doping Effect of Fluorinated Aromatic Hydrocarbon Solvents on the Performance of Common Olefin Metathesis Catalysts: Application in the Preparation of Biologically Active Compounds.CHEMINFORM, Issue 17 2009Cezary Samojlowicz Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Asymmetric Cyclopropanantion of Optically Active Vinyl Sulfoxides: A New Synthetic Approach to Biologically Active CompoundsCHEMINFORM, Issue 34 2005Wanda H. Midura Abstract For Abstract see ChemInform Abstract in Full Text. [source] Synthesis of 1-Nonanoyl/octadecanoyl-4-substituted Thiosemicarbazides and Substituted 1,2,4-Triazoles as Biologically Active Compounds.CHEMINFORM, Issue 11 2004Katica Colanceska-Ragenovic Abstract For Abstract see ChemInform Abstract in Full Text. [source] Synthesis of 1-Phenyl-3-(chromon-3-yl)prop-2-en-1-one Derivatives , A Novel Group of Biologically Active Compounds.CHEMINFORM, Issue 47 2002V. A. Tuskaev Abstract For Abstract see ChemInform Abstract in Full Text. [source] Pyrimidine as Constituent of Natural Biologically Active CompoundsCHEMISTRY & BIODIVERSITY, Issue 1 2005Irene This review describes the various manifestations of the pyrimidine system (alkylated, glycosylated, benzo-annelated.). These comprise pyrimidine nucleosides as well as alkaloids and antibiotics , some of them have been discovered and isolated from natural sources already long time ago, others have been reported very recently. A short overview on pyrimidine syntheses (prebiotic synthesis, biosynthesis, and metabolism) is given. The biological activities of most of the pyrimidine analogs are briefly described, and, in some cases, syntheses are formulated. [source] | ||||||||||||||||||||||